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Extract from the Register of European Patents

EP About this file: EP2678443

EP2678443 - METHOD FOR QUANTIFYING HUMAN DNA USING AN INTERNAL CONTROL [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  29.09.2017
Database last updated on 05.10.2024
Most recent event   Tooltip17.07.2020Lapse of the patent in a contracting state
New state(s): AL, IS		published on 19.08.2020  [2020/34]
Applicant(s)For all designated states
Qiagen GmbH
Qiagen Strasse 1
40724 Hilden / DE
For all designated states
QIAGEN Manchester Limited
Skelton House Lloyd Street North
Manchester M15 6SH / GB
[2014/01]
Inventor(s)01 / DI PASQUALE, Francesca
Derendorfer Strasse 70
40479 Düsseldorf / DE
02 / ENGEL, Holger
Käthe-Kollwitz-Weg 5
40724 Hilden / DE
03 / STRAUSS, Sascha
Bahnstrasse 8-10
42697 Solingen / DE
04 / THELWELL, Nicola, Jo
21 Norfolk Street
Glossop Derbyshire SK13 7QU / GB
 [2016/47]
Former [2014/01]01 / DI PASQUALE, Francesca
Derendorfer Strasse 70
40479 Düsseldorf / DE
02 / ENGEL, Holger
Käthe-Kollwitz-Weg 5
40724 Hilden / DE
03 / STRAU, Sascha
Bahnstrasse 8-10
42697 Solingen / DE
04 / THELWELL, Nicola, Jo
21 Norfolk Street
Glossop Derbyshire SK13 7QU / GB
Representative(s)CH Kilger Anwaltspartnerschaft mbB
Fasanenstraße 29
10719 Berlin / DE
[N/P]
Former [2016/47]CH Kilger Anwaltspartnerschaft mbB
Fasanenstrasse 29
10719 Berlin / DE
Former [2014/01]Fanelli Haag Kilger PLLC
Fasanenstrasse 29
10719 Berlin / DE
Application number, filing date12709012.420.02.2012
[2016/47]
WO2012EP00833
Priority number, dateEP2011015517821.02.2011         Original published format: EP 11155178
US201261588975P20.01.2012         Original published format: US 201261588975 P
[2014/01]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2012113577
Date:30.08.2012
Language:EN
[2012/35]
Type: A1 Application with search report 
No.:EP2678443
Date:01.01.2014
Language:EN
The application published by WIPO in one of the EPO official languages on 30.08.2012 takes the place of the publication of the European patent application.
[2014/01]
Type: B1 Patent specification 
No.:EP2678443
Date:23.11.2016
Language:EN
[2016/47]
Search report(s)International search report - published on:EP30.08.2012
ClassificationIPC:C12Q1/68
[2014/01]
CPC:
C12Q1/6851 (EP,CN,US); C12Q1/6888 (EP,CN,US); C12Q1/6879 (US);
C12Q2525/151 (CN); C12Q2545/101 (CN); C12Q2561/113 (CN);
C12Q2600/16 (EP,CN,US); C12Q2600/166 (EP,CN,US) (-)
C-Set:
C12Q1/6851, C12Q2525/151, C12Q2545/101, C12Q2561/113 (CN,EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2014/01]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:VERFAHREN ZUR QUANTIFIZIERUNG MENSCHLICHER DNA MITTELS EINER INTERNEN KONTROLLE[2016/18]
English:METHOD FOR QUANTIFYING HUMAN DNA USING AN INTERNAL CONTROL[2014/01]
French:PROCÉDÉ DE QUANTIFICATION D'ADN HUMAIN AU MOYEN D'UN TÉMOIN INTERNE[2014/01]
Former [2014/01]VERFAHREN ZUR QUANTIFIZIERUNG MENSCHLICHER DNA MITTELS EINER INTERNEN STEUERUNG
Entry into regional phase18.09.2013National basic fee paid 
18.09.2013Designation fee(s) paid 
18.09.2013Examination fee paid 
Examination procedure18.09.2013Examination requested  [2014/01]
18.03.2014Amendment by applicant (claims and/or description)
10.06.2014Despatch of a communication from the examining division (Time limit: M04)
05.08.2014Reply to a communication from the examining division
08.09.2014Despatch of a communication from the examining division (Time limit: M04)
24.10.2014Reply to a communication from the examining division
06.03.2015Despatch of a communication from the examining division (Time limit: M04)
10.07.2015Reply to a communication from the examining division
19.11.2015Despatch of a communication from the examining division (Time limit: M02)
25.11.2015Reply to a communication from the examining division
02.06.2016Communication of intention to grant the patent
11.10.2016Fee for grant paid
11.10.2016Fee for publishing/printing paid
11.10.2016Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  10.06.2014
Opposition(s)24.08.2017No opposition filed within time limit [2017/44]
Fees paidRenewal fee
20.02.2014Renewal fee patent year 03
23.02.2015Renewal fee patent year 04
22.02.2016Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU20.02.2012
AL23.11.2016
AT23.11.2016
BE23.11.2016
CY23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
HR23.11.2016
IT23.11.2016
LT23.11.2016
LV23.11.2016
MC23.11.2016
MK23.11.2016
NL23.11.2016
RS23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
SM23.11.2016
TR23.11.2016
IE20.02.2017
LU20.02.2017
MT20.02.2017
BG23.02.2017
NO23.02.2017
GR24.02.2017
IS23.03.2017
PT23.03.2017
[2020/33]
Former [2020/15]HU20.02.2012
AT23.11.2016
BE23.11.2016
CY23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
HR23.11.2016
IT23.11.2016
LT23.11.2016
LV23.11.2016
MC23.11.2016
MK23.11.2016
NL23.11.2016
RS23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
SM23.11.2016
TR23.11.2016
IE20.02.2017
LU20.02.2017
MT20.02.2017
BG23.02.2017
NO23.02.2017
GR24.02.2017
PT23.03.2017
Former [2019/51]HU20.02.2012
AT23.11.2016
BE23.11.2016
CY23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
HR23.11.2016
IT23.11.2016
LT23.11.2016
LV23.11.2016
MC23.11.2016
MK23.11.2016
NL23.11.2016
RS23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
SM23.11.2016
IE20.02.2017
LU20.02.2017
MT20.02.2017
BG23.02.2017
NO23.02.2017
GR24.02.2017
PT23.03.2017
Former [2019/46]HU20.02.2012
AT23.11.2016
BE23.11.2016
CY23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
HR23.11.2016
IT23.11.2016
LT23.11.2016
LV23.11.2016
MC23.11.2016
NL23.11.2016
RS23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
SM23.11.2016
IE20.02.2017
LU20.02.2017
MT20.02.2017
BG23.02.2017
NO23.02.2017
GR24.02.2017
PT23.03.2017
Former [2019/31]HU20.02.2012
AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
HR23.11.2016
IT23.11.2016
LT23.11.2016
LV23.11.2016
MC23.11.2016
NL23.11.2016
RS23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
SM23.11.2016
IE20.02.2017
LU20.02.2017
MT20.02.2017
BG23.02.2017
NO23.02.2017
GR24.02.2017
PT23.03.2017
Former [2018/43]AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
HR23.11.2016
IT23.11.2016
LT23.11.2016
LV23.11.2016
MC23.11.2016
NL23.11.2016
RS23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
SM23.11.2016
IE20.02.2017
LU20.02.2017
MT20.02.2017
BG23.02.2017
NO23.02.2017
GR24.02.2017
PT23.03.2017
Former [2018/13]AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
HR23.11.2016
IT23.11.2016
LT23.11.2016
LV23.11.2016
MC23.11.2016
NL23.11.2016
RS23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
SM23.11.2016
IE20.02.2017
LU20.02.2017
BG23.02.2017
NO23.02.2017
GR24.02.2017
PT23.03.2017
Former [2018/04]AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
HR23.11.2016
IT23.11.2016
LT23.11.2016
LV23.11.2016
MC23.11.2016
NL23.11.2016
RS23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
SM23.11.2016
LU20.02.2017
BG23.02.2017
NO23.02.2017
GR24.02.2017
PT23.03.2017
Former [2017/52]AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
HR23.11.2016
IT23.11.2016
LT23.11.2016
LV23.11.2016
MC23.11.2016
NL23.11.2016
RS23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
SM23.11.2016
BG23.02.2017
NO23.02.2017
GR24.02.2017
PT23.03.2017
Former [2017/42]AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
HR23.11.2016
IT23.11.2016
LT23.11.2016
LV23.11.2016
MC23.11.2016
NL23.11.2016
RS23.11.2016
SE23.11.2016
SK23.11.2016
SM23.11.2016
BG23.02.2017
NO23.02.2017
GR24.02.2017
PT23.03.2017
Former [2017/38]AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
HR23.11.2016
IT23.11.2016
LT23.11.2016
LV23.11.2016
NL23.11.2016
RS23.11.2016
SE23.11.2016
SK23.11.2016
SM23.11.2016
BG23.02.2017
NO23.02.2017
GR24.02.2017
PT23.03.2017
Former [2017/36]AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
HR23.11.2016
LT23.11.2016
LV23.11.2016
NL23.11.2016
RS23.11.2016
SE23.11.2016
SK23.11.2016
NO23.02.2017
GR24.02.2017
PT23.03.2017
Former [2017/33]AT23.11.2016
DK23.11.2016
ES23.11.2016
HR23.11.2016
LT23.11.2016
LV23.11.2016
NL23.11.2016
RS23.11.2016
SE23.11.2016
NO23.02.2017
GR24.02.2017
BE28.02.2017
PT23.03.2017
Former [2017/26]AT23.11.2016
ES23.11.2016
HR23.11.2016
LT23.11.2016
LV23.11.2016
NL23.11.2016
RS23.11.2016
SE23.11.2016
NO23.02.2017
GR24.02.2017
BE28.02.2017
PT23.03.2017
Former [2017/12]LV23.11.2016
Cited inInternational search[XYI]EP0714987  (IMMUNO AG [AT]) [X] 17 * examples 1-3; claim 1 * [Y] 1,3-10 [I] 18;
 [XI]WO03075837  (US ARMY MED RES MAT COMMAND [US], et al) [X] 17 * Examples * * paragraphs [0009] , [0010] , [0027] , [0070] * [I] 15,16,18;
 [X]US2007134655  (BENTWICH ITZHAK [IL]) [X] 17,18 * sequences 191099,88031,185375,80049 *;
 [XAI]WO2007126377  (VYTAL DIAGNOSTICS AB [SE], et al) [X] 17 * example 1 * [A] 2 [I] 18;
 [XI]US7374927  (PALMA JOHN F [US], et al) [X] 17 * sequences 35254, 35262, 35667, 35668 * [I] 18;
 [XYI]  - NIEDERSTATTER ET AL, "A modular real-time PCR concept for determining the quantity and quality of human nuclear and mitochondrial DNA", 20070201, (20070201), vol. 1, no. 1, pages 29 - 34, XP005942483 [X] 17 * abstract * * Materials and methods; Results and discussion * [Y] 1,3-10 [I] 18
 [XYI]  - SWANGO K L ET AL, "A quantitative PCR assay for the assessment of DNA degradation in forensic samples", FORENSIC SCIENCE INTERNATIONAL, ELSEVIER SCIENTIFIC PUBLISHERS IRELAND LTD, IE, vol. 158, no. 1, doi:DOI:10.1016/J.FORSCIINT.2005.04.034, ISSN 0379-0738, (20060420), pages 14 - 26, (20060420), XP025086123 [X] 17 * abstract * [Y] 1,3-10 [I] 18

DOI:   http://dx.doi.org/10.1016/j.forsciint.2005.04.034
    [ ] - "Sequence 35254 from patent US 7374927.", EMBL, (20080818), Database accession no. EA815487, URL: EBI [ ] * compound . *
    [ ] - "Sequence 35262 from patent US 7374927.", EMBL, (20080818), Database accession no. EA815495, URL: EBI [ ] * compound . *
    [ ] - "Sequence 35667 from patent US 7374927.", EMBL, (20080818), Database accession no. EA815900, URL: EBI [ ] * compound . *
    [ ] - "Sequence 35668 from patent US 7374927.", EMBL, (20080818), Database accession no. EA815901, URL: EBI [ ] * compound . *
 [Y]  - P. H. SUDMANT ET AL, "Diversity of Human Copy Number Variation and Multicopy Genes", SCIENCE, (20101029), vol. 330, no. 6004, doi:10.1126/science.1197005, ISSN 0036-8075, pages 641 - 646, XP055003891 [Y] 1,3-10,12,14,19 * the whole document *

DOI:   http://dx.doi.org/10.1126/science.1197005
 [I]  - "Homo sapiens cosmid clone XXcos-2185C13 from 7, complete sequence", EMBL, (20020227), XP002627315 [I] 11,13,18 * nts 16636-18635 *
    [ ] - "Sequence 191099 from patent US 7618814.", EMBL, (20091225), Database accession no. GV191099, URL: EBI [ ] * sequence . *
    [ ] - "Sequence 88031 from patent US 7618814.", EMBL, (20091225), Database accession no. GV088031, URL: EBI [ ] * sequence . *
    [ ] - "Sequence 185375 from patent US 7618814.", EMBL, (20091225), Database accession no. GV185375, URL: EBI [ ] * sequence . *
    [ ] - "Sequence 80049 from patent US 7618814.", EMBL, (20091225), Database accession no. GV080049, URL: EBI [ ] * sequence . *
 [I]  - "Homo sapiens chromosome Y clone RP11-363H7, WORKING DRAFT SEQUENCE", Nucleotide, NCBI, (20000817), Database accession no. AC011304, URL: http://www.ncbi.nlm.nih.gov/nuccore, XP002677807 [I] 12,14 * Nucleotides 81696-81825 *
 [Y]  - KRENKE B E ET AL, "Developmental validation of a real-time PCR assay for the simultaneous quantification of total human and male DNA", FORENSIC SCIENCE INTERNATIONAL: GENETICS, ELSEVIER BV, NETHERLANDS, vol. 3, no. 1, doi:10.1016/J.FSIGEN.2008.07.004, ISSN 1872-4973, (20081201), pages 14 - 21, (20081126), XP025694574 [Y] 1,3-10,19 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.fsigen.2008.07.004
 [XI]  - THELWELL N ET AL, "Mode of action and application of Scorpion primers to mutation detection", NUCLEIC ACIDS RESEARCH SPECIAL PUBLICATION, OXFORD UNIVERSITY PRESS, SURREY, GB, (20001001), vol. 28, no. 19, doi:10.1093/NAR/28.19.3752, ISSN 0305-1048, pages 3752 - 3761, XP002247004 [X] 17 * abstract * [I] 15,16,18

DOI:   http://dx.doi.org/10.1093/nar/28.19.3752
 [XI]  - JAYNE A. BATES ET AL, "Scorpion ARMS primers for SNP real-time PCR detection and quantification of Pyrenophora teres", MOLECULAR PLANT PATHOLOGY, (20010901), vol. 2, no. 5, doi:10.1046/j.1464-6722.2001.00074.x, ISSN 1464-6722, pages 275 - 280, XP055002650 [X] 17 * abstract * * page 275, column 1, paragraph 1 * * page 279, column 2 * [I] 15,16,18

DOI:   http://dx.doi.org/10.1046/j.1464-6722.2001.00074.x
 [XYI]  - PIERCE K E ET AL, "Real-time PCR using molecular beacons for accurate detection of the Y chromosome in single human blastomeres.", MOLECULAR HUMAN REPRODUCTION DEC 2000 LNKD- PUBMED:11101699, (200012), vol. 6, no. 12, ISSN 1360-9947, pages 1155 - 1164, XP002677808 [X] 17 * abstract * * page 1158, column 1, paragraph 2 * [Y] 1,3-10,12,14,19 [I] 18

DOI:   http://dx.doi.org/10.1093/molehr/6.12.1155
ExaminationWO2012038503
by applicantUS4458006
 US2009017453
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.