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Extract from the Register of European Patents

EP About this file: EP2691514

EP2691514 - CELLULAR SUBSTRATE FOR NUCLEAR REPROGRAMMING [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  13.07.2018
Database last updated on 30.09.2024
FormerThe patent has been granted
Status updated on  04.08.2017
FormerGrant of patent is intended
Status updated on  27.03.2017
Most recent event   Tooltip17.07.2020Lapse of the patent in a contracting state
New state(s): AL		published on 19.08.2020  [2020/34]
Applicant(s)For all designated states
Cambridge Enterprise Limited
The Old Schools
Trinity Lane
Cambridge
Cambridgeshire CB2 1TN / GB
[2017/36]
Former [2014/06]For all designated states
Cambridge Enterprise Ltd.
The Old Schools Trinity Lane Cambridge
Cambridgeshire CB2 1TN / GB
Inventor(s)01 / MORRELL, Nicholas
Department of Medicine
Level 5, Addenbrooke's Hospital (Box 157)
Hills Road
Cambridge, Cambridgeshire CB2 2QQ / GB
02 / ORMISTON, Mark
Department of Medicine
Level 5, Addenbrooke's Hospital (Box 157)
Hills Road
Cambridge, Cambridgeshire CB2 2QQ / GB
03 / RANA, Amer
Department of Medicine
Level 5, Addenbrooke's Hospital (Box 157)
Hills Road
Cambridge, Cambridgeshire CB2 2QQ / GB
04 / VALLIER, Ludovic
Anne McLaren Laboratory for Regenerative Medicine
West Forvie Building
Robinson Way
Addenbrookes Hospital
Cambridge, Cambridgeshire CB2 0SZ / GB
 [2017/36]
Former [2014/06]01 / MORRELL, Nicholas
Department of Medicine
Level 5, Addenbrooke's Hospital (Box 157)
Hills Road
Cambridge, Cambridgeshire CB2 2QQ / GB
02 / ORMISTON, Mark
Department of Medicine
Level 5, Addenbrooke's Hospital (Box 157)
Hills Road
Cambridge, Cambridgeshire CB2 2QQ / GB
03 / RANA, Amer
Department of Medicine
Level 5, Addenbrooke's Hospital (Box 157)
Hills Road
Cambridge, Cambridgeshire CB2 2QQ / GB
04 / VALLIER, Ludovic
Anne McLaren Laboratory for Regenerative Medicine
West Forvie Building
Robinson Way
Addenbrookes Hospital
Cambridge, Cambridgeshire CB2 0SZ / GB
Representative(s)Sutcliffe, Nicholas Robert, et al
Mewburn Ellis LLP
City Tower
40 Basinghall Street
London EC2V 5DE / GB
[2017/36]
Former [2014/06]Sutcliffe, Nicholas Robert, et al
Mewburn Ellis LLP
33 Gutter Lane
London
EC2V 8AS / GB
Application number, filing date12718729.230.03.2012
[2017/36]
WO2012GB50718
Priority number, dateGB2011000541330.03.2011         Original published format: GB 201105413
[2014/06]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2012131387
Date:04.10.2012
Language:EN
[2012/40]
Type: A1 Application with search report 
No.:EP2691514
Date:05.02.2014
Language:EN
The application published by WIPO in one of the EPO official languages on 04.10.2012 takes the place of the publication of the European patent application.
[2014/06]
Type: B1 Patent specification 
No.:EP2691514
Date:06.09.2017
Language:EN
[2017/36]
Search report(s)International search report - published on:EP04.10.2012
ClassificationIPC:C12N5/074
[2017/16]
CPC:
C12N5/0696 (EP,US); C12N2501/602 (EP,US); C12N2501/603 (EP,US);
C12N2501/604 (EP,US); C12N2501/606 (EP,US); C12N2506/28 (EP,US);
C12N2510/00 (EP,US) (-)
Former IPC [2014/06]C12N5/078
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2014/06]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:ZELLULÄRES SUBSTRAT ZUR KERNREPROGRAMMIERUNG[2017/16]
English:CELLULAR SUBSTRATE FOR NUCLEAR REPROGRAMMING[2014/06]
French:SUBSTRAT CELLULAIRE POUR LA REPROGRAMMATION NUCLÉAIRE[2017/16]
Former [2014/06]ZELLULARES SUBSTRAT FÜR DIE NUKLEÄRE REPROGRAMMIERUNG
Former [2014/06]SUBSTRAT CELLULAIRE POUR REPROGRAMMATION NUCLÉAIRE
Entry into regional phase08.10.2013National basic fee paid 
08.10.2013Designation fee(s) paid 
08.10.2013Examination fee paid 
Examination procedure25.09.2013Amendment by applicant (claims and/or description)
08.10.2013Examination requested  [2014/06]
30.10.2014Despatch of a communication from the examining division (Time limit: M06)
11.05.2015Reply to a communication from the examining division
19.10.2015Despatch of a communication from the examining division (Time limit: M06)
30.05.2016Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
22.07.2016Reply to a communication from the examining division
28.03.2017Communication of intention to grant the patent
24.07.2017Receipt of the translation of the claim(s)
25.07.2017Fee for grant paid
25.07.2017Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  30.10.2014
Opposition(s)07.06.2018No opposition filed within time limit [2018/33]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
22.07.2016Request for further processing filed
22.07.2016Full payment received (date of receipt of payment)
Request granted
03.08.2016Decision despatched
Fees paidRenewal fee
25.03.2014Renewal fee patent year 03
24.03.2015Renewal fee patent year 04
21.03.2016Renewal fee patent year 05
23.03.2017Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU30.03.2012
AL06.09.2017
AT06.09.2017
CY06.09.2017
CZ06.09.2017
DK06.09.2017
EE06.09.2017
ES06.09.2017
FI06.09.2017
HR06.09.2017
IT06.09.2017
LT06.09.2017
LV06.09.2017
MC06.09.2017
MK06.09.2017
PL06.09.2017
PT06.09.2017
RO06.09.2017
RS06.09.2017
SI06.09.2017
SK06.09.2017
SM06.09.2017
TR06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
IS06.01.2018
IE30.03.2018
LU30.03.2018
MT30.03.2018
BE31.03.2018
[2020/34]
Former [2020/31]HU30.03.2012
AT06.09.2017
CY06.09.2017
CZ06.09.2017
DK06.09.2017
EE06.09.2017
ES06.09.2017
FI06.09.2017
HR06.09.2017
IT06.09.2017
LT06.09.2017
LV06.09.2017
MC06.09.2017
MK06.09.2017
PL06.09.2017
PT06.09.2017
RO06.09.2017
RS06.09.2017
SI06.09.2017
SK06.09.2017
SM06.09.2017
TR06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
IS06.01.2018
IE30.03.2018
LU30.03.2018
MT30.03.2018
BE31.03.2018
Former [2020/27]HU30.03.2012
AT06.09.2017
CZ06.09.2017
DK06.09.2017
EE06.09.2017
ES06.09.2017
FI06.09.2017
HR06.09.2017
IT06.09.2017
LT06.09.2017
LV06.09.2017
MC06.09.2017
PL06.09.2017
PT06.09.2017
RO06.09.2017
RS06.09.2017
SI06.09.2017
SK06.09.2017
SM06.09.2017
TR06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
IS06.01.2018
IE30.03.2018
LU30.03.2018
MT30.03.2018
BE31.03.2018
Former [2020/16]AT06.09.2017
CZ06.09.2017
DK06.09.2017
EE06.09.2017
ES06.09.2017
FI06.09.2017
HR06.09.2017
IT06.09.2017
LT06.09.2017
LV06.09.2017
MC06.09.2017
PL06.09.2017
RO06.09.2017
RS06.09.2017
SI06.09.2017
SK06.09.2017
SM06.09.2017
TR06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
IS06.01.2018
IE30.03.2018
LU30.03.2018
MT30.03.2018
BE31.03.2018
Former [2020/08]AT06.09.2017
CZ06.09.2017
DK06.09.2017
EE06.09.2017
ES06.09.2017
FI06.09.2017
HR06.09.2017
IT06.09.2017
LT06.09.2017
LV06.09.2017
MC06.09.2017
PL06.09.2017
RO06.09.2017
RS06.09.2017
SI06.09.2017
SK06.09.2017
SM06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
IS06.01.2018
IE30.03.2018
LU30.03.2018
MT30.03.2018
BE31.03.2018
Former [2019/12]AT06.09.2017
CZ06.09.2017
DK06.09.2017
EE06.09.2017
ES06.09.2017
FI06.09.2017
HR06.09.2017
IT06.09.2017
LT06.09.2017
LV06.09.2017
MC06.09.2017
PL06.09.2017
RO06.09.2017
RS06.09.2017
SI06.09.2017
SK06.09.2017
SM06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
IS06.01.2018
IE30.03.2018
LU30.03.2018
BE31.03.2018
Former [2019/09]AT06.09.2017
CZ06.09.2017
DK06.09.2017
EE06.09.2017
ES06.09.2017
FI06.09.2017
HR06.09.2017
IT06.09.2017
LT06.09.2017
LV06.09.2017
MC06.09.2017
PL06.09.2017
RO06.09.2017
RS06.09.2017
SI06.09.2017
SK06.09.2017
SM06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
IS06.01.2018
IE30.03.2018
LU30.03.2018
Former [2019/04]AT06.09.2017
CZ06.09.2017
DK06.09.2017
EE06.09.2017
ES06.09.2017
FI06.09.2017
HR06.09.2017
IT06.09.2017
LT06.09.2017
LV06.09.2017
MC06.09.2017
PL06.09.2017
RO06.09.2017
RS06.09.2017
SI06.09.2017
SK06.09.2017
SM06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
IS06.01.2018
LU30.03.2018
Former [2018/52]AT06.09.2017
CZ06.09.2017
DK06.09.2017
EE06.09.2017
ES06.09.2017
FI06.09.2017
HR06.09.2017
IT06.09.2017
LT06.09.2017
LV06.09.2017
MC06.09.2017
PL06.09.2017
RO06.09.2017
RS06.09.2017
SI06.09.2017
SK06.09.2017
SM06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
IS06.01.2018
Former [2018/39]AT06.09.2017
CZ06.09.2017
DK06.09.2017
EE06.09.2017
ES06.09.2017
FI06.09.2017
HR06.09.2017
IT06.09.2017
LT06.09.2017
LV06.09.2017
PL06.09.2017
RO06.09.2017
RS06.09.2017
SI06.09.2017
SK06.09.2017
SM06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
IS06.01.2018
Former [2018/35]AT06.09.2017
CZ06.09.2017
DK06.09.2017
EE06.09.2017
ES06.09.2017
FI06.09.2017
HR06.09.2017
IT06.09.2017
LT06.09.2017
LV06.09.2017
PL06.09.2017
RO06.09.2017
RS06.09.2017
SK06.09.2017
SM06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
IS06.01.2018
Former [2018/24]AT06.09.2017
CZ06.09.2017
EE06.09.2017
ES06.09.2017
FI06.09.2017
HR06.09.2017
IT06.09.2017
LT06.09.2017
LV06.09.2017
PL06.09.2017
RO06.09.2017
RS06.09.2017
SK06.09.2017
SM06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
IS06.01.2018
Former [2018/23]AT06.09.2017
CZ06.09.2017
EE06.09.2017
ES06.09.2017
FI06.09.2017
HR06.09.2017
LT06.09.2017
LV06.09.2017
PL06.09.2017
RO06.09.2017
RS06.09.2017
SK06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
IS06.01.2018
Former [2018/21]CZ06.09.2017
ES06.09.2017
FI06.09.2017
HR06.09.2017
LT06.09.2017
LV06.09.2017
RS06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
Former [2018/12]ES06.09.2017
FI06.09.2017
HR06.09.2017
LT06.09.2017
LV06.09.2017
RS06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
Former [2018/11]ES06.09.2017
FI06.09.2017
HR06.09.2017
LT06.09.2017
RS06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
Former [2018/08]FI06.09.2017
LT06.09.2017
NO06.12.2017
Former [2018/07]LT06.09.2017
NO06.12.2017
Cited inInternational search[Y]WO2011032166  (UNIV JOHNS HOPKINS [US], et al) [Y] 1-39 * claims 1-31 *;
 [X]  - PESCE MAURIZIO ET AL, "Endothelial and cardiac progenitors: boosting, conditioning and (re)programming for cardiovascular repair.", PHARMACOLOGY & THERAPEUTICS JAN 2011 LNKD- PUBMED:21035506, (201101), vol. 129, no. 1, ISSN 1879-016X, pages 50 - 61, XP027562598 [X] 1-39 * page 51, column 1, paragraph 2 *
 [Y]  - PEARSON JEREMY D, "Endothelial progenitor cells--an evolving story.", MICROVASCULAR RESEARCH MAY 2010 LNKD- PUBMED:20043930, (201005), vol. 79, no. 3, ISSN 1095-9319, pages 162 - 168, XP027014621 [Y] 1-39 * page 163, column 1, paragraph 3 *
 [Y]  - PEARSON J D, "Endothelial progenitor cells - hype or hope?", JOURNAL OF THROMBOSIS AND HAEMOSTASIS, WILEY INTERSCIENCE, ENGLAND, vol. 7, no. 2, doi:10.1111/J.1538-7836.2008.03214.X, ISSN 1538-7836, (20090201), pages 255 - 262, (20090127), XP009160305 [Y] 1-39 * the whole document *

DOI:   http://dx.doi.org/10.1111/j.1538-7836.2008.03214.x
 [A]  - XIE XINXING ET AL, "Another possible cell source for cardiac regenerative medicine: reprogramming adult fibroblasts to cardiomyocytes and endothelial progenitor cells.", MEDICAL HYPOTHESES MAR 2011 LNKD- PUBMED:21087827, (201011), vol. 76, no. 3, ISSN 1532-2777, pages 365 - 367, XP028357559 [A] 1-39 * abstract *

DOI:   http://dx.doi.org/10.1016/j.mehy.2010.10.041
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.