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Extract from the Register of European Patents

EP About this file: EP2661507

EP2661507 - NONINVASIVE PRENATAL GENOTYPING OF FETAL SEX CHROMOSOMES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  12.02.2021
Database last updated on 14.06.2024
FormerThe patent has been granted
Status updated on  06.03.2020
FormerGrant of patent is intended
Status updated on  18.09.2019
FormerExamination is in progress
Status updated on  31.01.2019
Most recent event   Tooltip27.04.2024Lapse of the patent in a contracting state
New state(s): MK		published on 29.05.2024  [2024/22]
Applicant(s)For all designated states
The Chinese University Of Hong Kong
Shatin, N.T.
Hong Kong / CN
[2020/15]
Former [2013/46]For all designated states
The Chinese University Of Hong Kong
Shatin, N.T.
Hong Kong / CN
Inventor(s)01 / LO, Yuk Ming Dennis
4th Floor
7 King Tak Street Homantin
Kowloon Hong Kong / CN
02 / CHIU, Wai, Kwun, Rossa
House 31
Double Haven 52 Ma Lok Path
Shatin
New Territories
Hong Kong / CN
03 / CHAN, Kwan, Chee
Flat A, 13/F, Block 34
Broadway Street
Mei Foo Sun Chuen
Kowloon
Hong Kong / CN
04 / TSUI, Bo, Yin
Rm H, 2/F, Block 3
Bayshore Towers
Ma On Shan
New Territories
Hong Kong / CN
 [2013/46]
Representative(s)J A Kemp LLP
80 Turnmill Street
London EC1M 5QU / GB
[N/P]
Former [2020/15]J A Kemp LLP
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Former [2014/18]Roques, Sarah Elizabeth
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Former [2013/46]Harrison, Susan Joan, et al
Mewburn Ellis LLP
33 Gutter Lane
London
EC2V 8AS / GB
Application number, filing date12732095.005.01.2012
[2020/15]
WO2012IB00015
Priority number, dateUS201161430032P05.01.2011         Original published format: US 201161430032 P
US201161475632P14.04.2011         Original published format: US 201161475632 P
[2013/46]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2012093331
Date:12.07.2012
Language:EN
[2012/28]
Type: A1 Application with search report 
No.:EP2661507
Date:13.11.2013
Language:EN
The application published by WIPO in one of the EPO official languages on 12.07.2012 takes the place of the publication of the European patent application.
[2013/46]
Type: B1 Patent specification 
No.:EP2661507
Date:08.04.2020
Language:EN
[2020/15]
Search report(s)International search report - published on:AU12.07.2012
(Supplementary) European search report - dispatched on:EP25.11.2015
ClassificationIPC:G16B20/20
[2019/40]
CPC:
C12Q1/6883 (EP,US); G16B20/20 (EP,US); G16B20/00 (US);
G16B20/10 (EP); G16B20/50 (EP); G16B30/00 (US);
G16B40/00 (EP,US); C12Q2600/156 (EP,US); C12Q2600/158 (EP,US) (-)
Former IPC [2015/52]G06F19/00
Former IPC [2013/46]C12Q1/68, G06F19/00
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/46]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:NICHTINVASIVE PRÄNATALE GENOTYPISIERUNG FÖTALER GESCHLECHTSCHROMOSOMEN[2013/46]
English:NONINVASIVE PRENATAL GENOTYPING OF FETAL SEX CHROMOSOMES[2013/46]
French:GÉNOTYPAGE PRÉNATAL NON INVASIF DE CHROMOSOMES SEXUELS FÉTAUX[2019/42]
Former [2013/46]GÉNOTYPAGE PRÉNATAL NON INVASIF DE CHROMOSOMES SEXUELS F TAUX
Entry into regional phase29.07.2013National basic fee paid 
29.07.2013Search fee paid 
29.07.2013Designation fee(s) paid 
29.07.2013Examination fee paid 
Examination procedure29.07.2013Examination requested  [2013/46]
13.06.2016Amendment by applicant (claims and/or description)
04.02.2019Despatch of a communication from the examining division (Time limit: M06)
15.07.2019Reply to a communication from the examining division
19.09.2019Communication of intention to grant the patent
20.12.2019Fee for grant paid
20.12.2019Fee for publishing/printing paid
20.12.2019Receipt of the translation of the claim(s)
Divisional application(s)EP20151773.7  / EP3680909
EP21172847.2  / EP3901955
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  04.02.2019
Opposition(s)12.01.2021No opposition filed within time limit [2021/11]
Fees paidRenewal fee
21.01.2014Renewal fee patent year 03
13.01.2015Renewal fee patent year 04
11.01.2016Renewal fee patent year 05
11.01.2017Renewal fee patent year 06
15.01.2018Renewal fee patent year 07
15.01.2019Renewal fee patent year 08
14.01.2020Renewal fee patent year 09
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU05.01.2012
AL08.04.2020
AT08.04.2020
CY08.04.2020
CZ08.04.2020
DK08.04.2020
EE08.04.2020
ES08.04.2020
FI08.04.2020
HR08.04.2020
IT08.04.2020
LT08.04.2020
LV08.04.2020
MC08.04.2020
MK08.04.2020
NL08.04.2020
PL08.04.2020
RO08.04.2020
RS08.04.2020
SE08.04.2020
SI08.04.2020
SK08.04.2020
SM08.04.2020
BG08.07.2020
NO08.07.2020
GR09.07.2020
IS08.08.2020
PT17.08.2020
IE05.01.2021
LU05.01.2021
[2024/22]
Former [2023/27]HU05.01.2012
AL08.04.2020
AT08.04.2020
CY08.04.2020
CZ08.04.2020
DK08.04.2020
EE08.04.2020
ES08.04.2020
FI08.04.2020
HR08.04.2020
IT08.04.2020
LT08.04.2020
LV08.04.2020
MC08.04.2020
NL08.04.2020
PL08.04.2020
RO08.04.2020
RS08.04.2020
SE08.04.2020
SI08.04.2020
SK08.04.2020
SM08.04.2020
BG08.07.2020
NO08.07.2020
GR09.07.2020
IS08.08.2020
PT17.08.2020
IE05.01.2021
LU05.01.2021
Former [2023/24]AL08.04.2020
AT08.04.2020
CY08.04.2020
CZ08.04.2020
DK08.04.2020
EE08.04.2020
ES08.04.2020
FI08.04.2020
HR08.04.2020
IT08.04.2020
LT08.04.2020
LV08.04.2020
MC08.04.2020
NL08.04.2020
PL08.04.2020
RO08.04.2020
RS08.04.2020
SE08.04.2020
SI08.04.2020
SK08.04.2020
SM08.04.2020
BG08.07.2020
NO08.07.2020
GR09.07.2020
IS08.08.2020
PT17.08.2020
IE05.01.2021
LU05.01.2021
Former [2022/07]AL08.04.2020
AT08.04.2020
CZ08.04.2020
DK08.04.2020
EE08.04.2020
ES08.04.2020
FI08.04.2020
HR08.04.2020
IT08.04.2020
LT08.04.2020
LV08.04.2020
MC08.04.2020
NL08.04.2020
PL08.04.2020
RO08.04.2020
RS08.04.2020
SE08.04.2020
SI08.04.2020
SK08.04.2020
SM08.04.2020
BG08.07.2020
NO08.07.2020
GR09.07.2020
IS08.08.2020
PT17.08.2020
IE05.01.2021
LU05.01.2021
Former [2021/43]AL08.04.2020
AT08.04.2020
CZ08.04.2020
DK08.04.2020
EE08.04.2020
ES08.04.2020
FI08.04.2020
HR08.04.2020
IT08.04.2020
LT08.04.2020
LV08.04.2020
MC08.04.2020
NL08.04.2020
PL08.04.2020
RO08.04.2020
RS08.04.2020
SE08.04.2020
SI08.04.2020
SK08.04.2020
SM08.04.2020
BG08.07.2020
NO08.07.2020
GR09.07.2020
IS08.08.2020
PT17.08.2020
LU05.01.2021
Former [2021/40]AL08.04.2020
AT08.04.2020
CZ08.04.2020
DK08.04.2020
EE08.04.2020
ES08.04.2020
FI08.04.2020
HR08.04.2020
IT08.04.2020
LT08.04.2020
LV08.04.2020
MC08.04.2020
NL08.04.2020
PL08.04.2020
RO08.04.2020
RS08.04.2020
SE08.04.2020
SI08.04.2020
SK08.04.2020
SM08.04.2020
BG08.07.2020
NO08.07.2020
GR09.07.2020
IS08.08.2020
PT17.08.2020
Former [2021/24]AL08.04.2020
AT08.04.2020
CZ08.04.2020
DK08.04.2020
EE08.04.2020
ES08.04.2020
FI08.04.2020
HR08.04.2020
IT08.04.2020
LT08.04.2020
LV08.04.2020
NL08.04.2020
PL08.04.2020
RO08.04.2020
RS08.04.2020
SE08.04.2020
SI08.04.2020
SK08.04.2020
SM08.04.2020
BG08.07.2020
NO08.07.2020
GR09.07.2020
IS08.08.2020
PT17.08.2020
Former [2021/10]AL08.04.2020
AT08.04.2020
CZ08.04.2020
DK08.04.2020
EE08.04.2020
ES08.04.2020
FI08.04.2020
HR08.04.2020
IT08.04.2020
LT08.04.2020
LV08.04.2020
NL08.04.2020
PL08.04.2020
RO08.04.2020
RS08.04.2020
SE08.04.2020
SK08.04.2020
SM08.04.2020
BG08.07.2020
NO08.07.2020
GR09.07.2020
IS08.08.2020
PT17.08.2020
Former [2021/09]AL08.04.2020
AT08.04.2020
CZ08.04.2020
DK08.04.2020
EE08.04.2020
ES08.04.2020
FI08.04.2020
HR08.04.2020
IT08.04.2020
LT08.04.2020
LV08.04.2020
NL08.04.2020
RO08.04.2020
RS08.04.2020
SE08.04.2020
SM08.04.2020
BG08.07.2020
NO08.07.2020
GR09.07.2020
IS08.08.2020
PT17.08.2020
Former [2021/08]AL08.04.2020
DK08.04.2020
ES08.04.2020
FI08.04.2020
HR08.04.2020
LT08.04.2020
LV08.04.2020
NL08.04.2020
RO08.04.2020
RS08.04.2020
SE08.04.2020
SM08.04.2020
BG08.07.2020
NO08.07.2020
GR09.07.2020
IS08.08.2020
PT17.08.2020
Former [2021/04]AL08.04.2020
FI08.04.2020
HR08.04.2020
LT08.04.2020
LV08.04.2020
NL08.04.2020
RS08.04.2020
SE08.04.2020
BG08.07.2020
NO08.07.2020
GR09.07.2020
IS08.08.2020
PT17.08.2020
Former [2021/01]FI08.04.2020
HR08.04.2020
LT08.04.2020
LV08.04.2020
NL08.04.2020
RS08.04.2020
SE08.04.2020
BG08.07.2020
NO08.07.2020
GR09.07.2020
IS08.08.2020
PT17.08.2020
Former [2020/51]FI08.04.2020
HR08.04.2020
LT08.04.2020
LV08.04.2020
NL08.04.2020
RS08.04.2020
SE08.04.2020
NO08.07.2020
GR09.07.2020
IS08.08.2020
PT17.08.2020
Former [2020/50]FI08.04.2020
HR08.04.2020
LT08.04.2020
LV08.04.2020
NL08.04.2020
SE08.04.2020
NO08.07.2020
GR09.07.2020
IS08.08.2020
PT17.08.2020
Former [2020/48]FI08.04.2020
LT08.04.2020
NL08.04.2020
SE08.04.2020
NO08.07.2020
IS08.08.2020
PT17.08.2020
Former [2020/47]LT08.04.2020
NO08.07.2020
IS08.08.2020
Former [2020/46]IS08.08.2020
Documents cited:Search[I]  - NOUREDDINE EL KAROUI1 ET AL, "Getting more from digital SNP data", STATISTICS IN MEDICINE, WILEY, NEW YORK, NY, US, vol. 25, doi:10.1002/SIM.2379, ISSN 0277-6715, (20060101), pages 3124 - 3133, (20060105), XP007905913 [I] 1-15 * whole document, in particular plate 4, appendix A.2 *

DOI:   http://dx.doi.org/10.1002/sim.2379
International search[A]  - LUN, F. M. F. ET AL., "Noninvasive prenatal diagnosis of monogenic diseases by digital size selection and relative mutation dosage on DNA in maternal plasma", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE USA, (20081216), vol. 105, no. 50, pages 19920 - 19925, XP002620453

DOI:   http://dx.doi.org/10.1073/pnas.0810373105
 [A]  - CHIU, R. W. K. ET AL., "Application of fetal DNA in maternal plasma for noninvasive prenatal diagnosis", EXPERT REVIEW OF MOLECULAR DIAGNOSTICS, (200201), vol. 2, no. 1, pages 32 - 40, XP008171176

DOI:   http://dx.doi.org/10.1586/14737159.2.1.32
 [XP]  - TSUI, N. B. Y. ET AL., "Noninvasive prenatal diagnosis of hemophilia by microfluidics digital PCR analysis of maternal plasma DNA", BLOOD, (20110331), vol. 117, no. 13, pages 3684 - 3691, XP055129825

DOI:   http://dx.doi.org/10.1182/blood-2010-10-310789
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