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Extract from the Register of European Patents

EP About this file: EP2723360

EP2723360 - CCR2 ANTAGONIST PEPTIDES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  06.04.2018
Database last updated on 14.06.2024
FormerThe patent has been granted
Status updated on  28.04.2017
FormerGrant of patent is intended
Status updated on  15.12.2016
Most recent event   Tooltip17.07.2020Lapse of the patent in a contracting state
New state(s): AL
published on 19.08.2020  [2020/34]
Applicant(s)For all designated states
Université Pierre et Marie Curie (Paris 6)
4, Place Jussieu
75005 Paris / FR
[2014/18]
Inventor(s)01 / COMBADIERE, Christophe
18 rue de Réage
F-77700 Magny Le Hongre / FR
02 / SENNLAUB, Florian
117 Bd Voltaire
F-75011 Paris / FR
03 / AUVYNET, Constance
1 rue Mayet
F-75006 Paris / FR
04 / CHEMTOB, Sylvain
6885 Banting Rd
Cote St Luc, Québec H4W 1G1 / CA
05 / QUINIOU, Christiane
4574 Euclide-Brien Apt. 204
Montreal, Québec / CA
 [2014/18]
Representative(s)Chajmowicz, Marion, et al
Becker & Associés
25, Rue Louis Le Grand
75002 Paris / FR
[N/P]
Former [2014/18]Chajmowicz, Marion, et al
Becker & Associés
25, rue Louis Le Grand
75002 Paris / FR
Application number, filing date12733026.426.06.2012
[2017/22]
WO2012EP62379
Priority number, dateEP2011030581627.06.2011         Original published format: EP 11305816
[2014/18]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2013000922
Date:03.01.2013
Language:EN
[2013/01]
Type: A1 Application with search report 
No.:EP2723360
Date:30.04.2014
Language:EN
The application published by WIPO in one of the EPO official languages on 03.01.2013 takes the place of the publication of the European patent application.
[2014/18]
Type: B1 Patent specification 
No.:EP2723360
Date:31.05.2017
Language:EN
[2017/22]
Search report(s)International search report - published on:EP03.01.2013
(Supplementary) European search report - dispatched on:EP24.02.2015
ClassificationIPC:A61K38/04, C07K7/00, A61K38/00
[2014/18]
CPC:
C07K14/7158 (EP,US); A61K38/1793 (EP,US); A61K47/60 (EP,US);
A61P1/00 (EP); A61P1/02 (EP); A61P1/04 (EP);
A61P11/00 (EP); A61P11/06 (EP); A61P13/12 (EP);
A61P17/04 (EP); A61P17/06 (EP); A61P19/02 (EP);
A61P25/00 (EP); A61P25/04 (EP); A61P27/02 (EP);
A61P27/14 (EP); A61P29/00 (EP); A61P3/10 (EP);
A61P31/00 (EP); A61P31/06 (EP); A61P35/00 (EP);
A61P35/02 (EP); A61P37/06 (EP); A61P37/08 (EP);
A61P9/10 (EP); C07K7/06 (EP,US); C07K7/08 (US);
A61K38/00 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2014/18]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:CCR2-ANTAGONISTENPEPTIDE[2014/18]
English:CCR2 ANTAGONIST PEPTIDES[2014/18]
French:PEPTIDES ANTAGONISTES DE CCR2[2014/18]
Entry into regional phase24.01.2014National basic fee paid 
24.01.2014Designation fee(s) paid 
24.01.2014Examination fee paid 
Examination procedure24.01.2014Amendment by applicant (claims and/or description)
24.01.2014Examination requested  [2014/18]
24.02.2015Despatch of a communication from the examining division to which search results under Rule 164(2) EPC are annexed (Time limit: M04) [2015/13]
24.02.2015Despatch of a communication from the examining division (Time limit: M04)
25.06.2015Reply to a communication from the examining division
29.07.2015Despatch of a communication from the examining division (Time limit: M06)
18.01.2016Reply to a communication from the examining division
28.01.2016Despatch of a communication from the examining division (Time limit: M06)
13.07.2016Reply to a communication from the examining division
26.07.2016Despatch of a communication from the examining division (Time limit: M04)
07.10.2016Reply to a communication from the examining division
16.12.2016Communication of intention to grant the patent
18.04.2017Fee for grant paid
18.04.2017Fee for publishing/printing paid
18.04.2017Receipt of the translation of the claim(s)
Divisional application(s)EP17170870.4  / EP3257519
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  24.02.2015
Opposition(s)01.03.2018No opposition filed within time limit [2018/19]
Fees paidRenewal fee
28.11.2014Renewal fee patent year 03
18.06.2015Renewal fee patent year 04
13.06.2016Renewal fee patent year 05
Penalty fee
Additional fee for renewal fee
30.06.201403   M06   Fee paid on   28.11.2014
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See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU26.06.2012
AL31.05.2017
AT31.05.2017
CY31.05.2017
CZ31.05.2017
EE31.05.2017
FI31.05.2017
HR31.05.2017
LT31.05.2017
LV31.05.2017
MC31.05.2017
MK31.05.2017
NL31.05.2017
PL31.05.2017
PT31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SI31.05.2017
SK31.05.2017
SM31.05.2017
TR31.05.2017
IE26.06.2017
LU26.06.2017
MT26.06.2017
BE30.06.2017
CH30.06.2017
LI30.06.2017
BG31.08.2017
GR01.09.2017
IS30.09.2017
[2020/34]
Former [2020/27]HU26.06.2012
AT31.05.2017
CY31.05.2017
CZ31.05.2017
EE31.05.2017
FI31.05.2017
HR31.05.2017
LT31.05.2017
LV31.05.2017
MC31.05.2017
MK31.05.2017
NL31.05.2017
PL31.05.2017
PT31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SI31.05.2017
SK31.05.2017
SM31.05.2017
TR31.05.2017
IE26.06.2017
LU26.06.2017
MT26.06.2017
BE30.06.2017
CH30.06.2017
LI30.06.2017
BG31.08.2017
GR01.09.2017
IS30.09.2017
Former [2020/15]HU26.06.2012
AT31.05.2017
CY31.05.2017
CZ31.05.2017
EE31.05.2017
FI31.05.2017
HR31.05.2017
LT31.05.2017
LV31.05.2017
MC31.05.2017
MK31.05.2017
NL31.05.2017
PL31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SI31.05.2017
SK31.05.2017
SM31.05.2017
TR31.05.2017
IE26.06.2017
LU26.06.2017
MT26.06.2017
BE30.06.2017
CH30.06.2017
LI30.06.2017
BG31.08.2017
GR01.09.2017
IS30.09.2017
Former [2019/51]HU26.06.2012
AT31.05.2017
CY31.05.2017
CZ31.05.2017
EE31.05.2017
FI31.05.2017
HR31.05.2017
LT31.05.2017
LV31.05.2017
MC31.05.2017
MK31.05.2017
NL31.05.2017
PL31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SI31.05.2017
SK31.05.2017
SM31.05.2017
IE26.06.2017
LU26.06.2017
MT26.06.2017
BE30.06.2017
CH30.06.2017
LI30.06.2017
BG31.08.2017
GR01.09.2017
IS30.09.2017
Former [2019/46]HU26.06.2012
AT31.05.2017
CY31.05.2017
CZ31.05.2017
EE31.05.2017
FI31.05.2017
HR31.05.2017
LT31.05.2017
LV31.05.2017
MC31.05.2017
NL31.05.2017
PL31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SI31.05.2017
SK31.05.2017
SM31.05.2017
IE26.06.2017
LU26.06.2017
MT26.06.2017
BE30.06.2017
CH30.06.2017
LI30.06.2017
BG31.08.2017
GR01.09.2017
IS30.09.2017
Former [2019/31]HU26.06.2012
AT31.05.2017
CZ31.05.2017
EE31.05.2017
FI31.05.2017
HR31.05.2017
LT31.05.2017
LV31.05.2017
MC31.05.2017
NL31.05.2017
PL31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SI31.05.2017
SK31.05.2017
SM31.05.2017
IE26.06.2017
LU26.06.2017
MT26.06.2017
BE30.06.2017
CH30.06.2017
LI30.06.2017
BG31.08.2017
GR01.09.2017
IS30.09.2017
Former [2019/30]AT31.05.2017
CZ31.05.2017
EE31.05.2017
FI31.05.2017
HR31.05.2017
LT31.05.2017
LV31.05.2017
MC31.05.2017
NL31.05.2017
PL31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SI31.05.2017
SK31.05.2017
SM31.05.2017
IE26.06.2017
LU26.06.2017
MT26.06.2017
BE30.06.2017
CH30.06.2017
LI30.06.2017
BG31.08.2017
GR01.09.2017
IS30.09.2017
Former [2018/43]AT31.05.2017
CZ31.05.2017
EE31.05.2017
FI31.05.2017
HR31.05.2017
LT31.05.2017
LV31.05.2017
NL31.05.2017
PL31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SI31.05.2017
SK31.05.2017
SM31.05.2017
IE26.06.2017
LU26.06.2017
MT26.06.2017
BE30.06.2017
CH30.06.2017
LI30.06.2017
BG31.08.2017
GR01.09.2017
IS30.09.2017
Former [2018/39]AT31.05.2017
CZ31.05.2017
EE31.05.2017
FI31.05.2017
HR31.05.2017
LT31.05.2017
LV31.05.2017
NL31.05.2017
PL31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SI31.05.2017
SK31.05.2017
SM31.05.2017
IE26.06.2017
LU26.06.2017
BE30.06.2017
CH30.06.2017
LI30.06.2017
BG31.08.2017
GR01.09.2017
IS30.09.2017
Former [2018/23]AT31.05.2017
CZ31.05.2017
EE31.05.2017
FI31.05.2017
HR31.05.2017
LT31.05.2017
LV31.05.2017
NL31.05.2017
PL31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SI31.05.2017
SK31.05.2017
SM31.05.2017
IE26.06.2017
LU26.06.2017
CH30.06.2017
LI30.06.2017
BG31.08.2017
GR01.09.2017
IS30.09.2017
Former [2018/21]AT31.05.2017
CZ31.05.2017
EE31.05.2017
FI31.05.2017
HR31.05.2017
LT31.05.2017
LV31.05.2017
NL31.05.2017
PL31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SK31.05.2017
SM31.05.2017
LU26.06.2017
CH30.06.2017
LI30.06.2017
BG31.08.2017
GR01.09.2017
IS30.09.2017
Former [2018/11]AT31.05.2017
CZ31.05.2017
EE31.05.2017
FI31.05.2017
HR31.05.2017
LT31.05.2017
LV31.05.2017
NL31.05.2017
PL31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SK31.05.2017
SM31.05.2017
BG31.08.2017
GR01.09.2017
IS30.09.2017
Former [2018/10]AT31.05.2017
CZ31.05.2017
EE31.05.2017
FI31.05.2017
HR31.05.2017
LT31.05.2017
LV31.05.2017
NL31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SK31.05.2017
BG31.08.2017
GR01.09.2017
IS30.09.2017
Former [2018/09]AT31.05.2017
EE31.05.2017
FI31.05.2017
HR31.05.2017
LT31.05.2017
LV31.05.2017
NL31.05.2017
RS31.05.2017
SE31.05.2017
BG31.08.2017
GR01.09.2017
IS30.09.2017
Former [2017/52]AT31.05.2017
FI31.05.2017
HR31.05.2017
LT31.05.2017
LV31.05.2017
NL31.05.2017
RS31.05.2017
SE31.05.2017
BG31.08.2017
GR01.09.2017
IS30.09.2017
Former [2017/50]AT31.05.2017
FI31.05.2017
HR31.05.2017
LT31.05.2017
LV31.05.2017
RS31.05.2017
SE31.05.2017
BG31.08.2017
GR01.09.2017
IS30.09.2017
Former [2017/49]AT31.05.2017
FI31.05.2017
HR31.05.2017
LT31.05.2017
GR01.09.2017
IS30.09.2017
Documents cited:Search[X]WO9845322  (ROYAL NETHERLANDS ACADEMY OF A [NL], et al) [X] 1-3,5 * figure 6 *
International search[X]US2005037430  (KHAN NISAR AHMED [NL], et al) [X] 1,4,8,9,12 * page 6, column l, paragraph 61; sequence 257 *;
 [X]WO0131006  (UNIV NEBRASKA [US], et al) [X] 1,8,9,12 * sequence 17 *;
 [X]WO2009106073  (DAKO DENMARK AS [DK], et al) [X] 1,8,9,12 * sequence 39804 *;
 [Y]  - STRUTHERS M ET AL, "CCR2 Antagonists", CURRENT TOPICS IN MEDICINAL CHEMISTRY, BENTHAM SCIENCE PUBLISHERS LTD, NETHERLANDS, (20100101), vol. 10, no. 13, ISSN 1568-0266, pages 1278 - 1298, XP002641076 [Y] 1-17 * the whole document * * page 1292 - page 1293 * * page 1293, column r, paragraph 4 *
 [Y]  - XIA MINGDE ET AL, "Recent developments in CCR2 antagonists.", EXPERT OPINION ON THERAPEUTIC PATENTS MAR 2009 LNKD- PUBMED:19441905, (200903), vol. 19, no. 3, ISSN 1744-7674, pages 295 - 303, XP002660853 [Y] 1-17 * the whole document * * page 301 *

DOI:   http://dx.doi.org/10.1517/13543770902755129
 [Y]  - GONG J-H ET AL, "AN ANTAGONIST OF MONOCYTE CHEMOATTRACTANT PROTEIN 1 (MCP-1) INHIBITS ARTHRITIS IN THE MRL-LPR MOUSE MODEL", THE JOURNAL OF EXPERIMENTAL MEDICINE, ROCKEFELLER UNIVERSITY PRESS, US, (19970101), vol. 180, no. 1, doi:10.1084/JEM.186.1.131, ISSN 0022-1007, pages 131 - 137, XP002919550 [Y] 1-17 * the whole document *

DOI:   http://dx.doi.org/10.1084/jem.186.1.131
 [Y]  - MCQUIBBAN G ANGUS ET AL, "Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo.", BLOOD 15 AUG 2002 LNKD- PUBMED:12149192, (20020815), vol. 100, no. 4, ISSN 0006-4971, pages 1160 - 1167, XP002660854 [Y] 1-17 * the whole document * * page 1162 - page 1163 *
ExaminationWO9845322
by applicantUS7566539
 US2007184015
    - ROLLINS B J, "Monocyte chemoattractant protein 1: a potential regulator of monocyte recruitment in inflammatory disease", MOL. MED. TODAY, (1996), vol. 2, page 198
    - DAWSON J ET AL., "Targeting monocyte chemoattractant protein-1 signaling in disease", EXPERT OPIN. THER. TARGETS, (200302), vol. 7, no. 1, pages 35 - 48
    - BRODMERKEL ET AL., J. IMMUNOL, (2005), vol. 175, pages 5370 - 7378
    - WALENSKY ET AL., SCIENCE, (2004), vol. 305, pages 1466 - 1470
    - VANHOYE ET AL., BIOCHEMISTRY, (2004), vol. 43, no. 26, pages 8391 - 409
    - EPHREM ET AL., BLOOD, (20080115), vol. 111, no. 2, pages 715 - 22
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.