EP2689020 - MICROBIAL PRODUCTION OF CHEMICAL PRODUCTS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 22.03.2019 Database last updated on 24.08.2024 | |
Former | The patent has been granted Status updated on 13.04.2018 | ||
Former | Grant of patent is intended Status updated on 28.02.2018 | ||
Former | Examination is in progress Status updated on 23.01.2018 | ||
Former | Grant of patent is intended Status updated on 21.09.2017 | ||
Former | Examination is in progress Status updated on 18.11.2016 | Most recent event Tooltip | 01.07.2022 | Lapse of the patent in a contracting state New state(s): MK | published on 03.08.2022 [2022/31] | Applicant(s) | For all designated states OPX Biotechnologies Inc. 2425 55th Street Suite 100 Boulder, CO 80301 / US | [2018/20] |
Former [2014/05] | For all designated states OPX Biotechnologies Inc. 2425 55th Street Suite 100 Boulder, CO 80301 / US | Inventor(s) | 01 /
LYNCH, Michael, D. 2425 55th Street, Suite 100 Boulder, CO 80301 / US | 02 /
LIPSCOMB, Tanya, E.w. 2425 55th Street, Suite 100 Boulder, CO 80301 / US | 03 /
TRAHAN, Ashley, D. 2425 55th Street, Suite 100 Boulder, CO 80301 / US | 04 /
SINGH, Amar 2425 55th Street, Suite 100 Boulder, CO 80301 / US | 05 /
WOLTER, Travis 2425 55th Street, Suite 100 Boulder, CO 80301 / US | [2014/05] | Representative(s) | Gowshall, Jonathan Vallance Forresters IP LLP Skygarden Erika-Mann-Strasse 11 80636 München / DE | [2018/20] |
Former [2014/05] | Longland, Emma Louise avidity IP Kestrel House Falconry Court Baker's Lane Epping, Essex CM16 5DQ / GB | Application number, filing date | 12759932.2 | 22.03.2012 | [2018/20] | WO2012US30209 | Priority number, date | US201161466363P | 22.03.2011 Original published format: US 201161466363 P | US201161466433P | 22.03.2011 Original published format: US 201161466433 P | US201161539378P | 26.09.2011 Original published format: US 201161539378 P | US201161539162P | 26.09.2011 Original published format: US 201161539162 P | [2014/05] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2012129450 | Date: | 27.09.2012 | Language: | EN | [2012/39] | Type: | A1 Application with search report | No.: | EP2689020 | Date: | 29.01.2014 | Language: | EN | The application published by WIPO in one of the EPO official languages on 27.09.2012 takes the place of the publication of the European patent application. | [2014/05] | Type: | B1 Patent specification | No.: | EP2689020 | Date: | 16.05.2018 | Language: | EN | [2018/20] | Search report(s) | International search report - published on: | US | 27.09.2012 | (Supplementary) European search report - dispatched on: | EP | 01.12.2014 | Classification | IPC: | C12P1/00 | [2014/05] | CPC: |
C12P7/6409 (EP,US);
C07C53/126 (US);
C12N15/70 (US);
C12N9/001 (EP,US);
C12N9/1029 (EP,US);
C12P13/14 (EP,US);
C12P7/00 (EP,US);
C12P7/22 (EP,US);
C12P7/42 (EP,US);
C12P7/52 (EP,US);
C12P7/625 (EP,US);
C12Y103/01 (EP,US);
C12Y203/01041 (EP,US)
(-)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2014/05] | Extension states | BA | Not yet paid | ME | Not yet paid | Title | German: | MIKROBIELLE HERSTELLUNG CHEMISCHER PRODUKTE UND ZUSAMMENSETZUNGEN DARAUS SOWIE VERFAHREN UND SYSTEME DAFÜR | [2014/05] | English: | MICROBIAL PRODUCTION OF CHEMICAL PRODUCTS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | [2014/05] | French: | PRODUCTION MICROBIENNE DE PRODUITS CHIMIQUES, ET COMPOSITIONS, PROCÉDÉS ET SYSTÈMES ASSOCIÉS | [2014/05] | Entry into regional phase | 30.09.2013 | National basic fee paid | 30.09.2013 | Search fee paid | 30.09.2013 | Designation fee(s) paid | 30.09.2013 | Examination fee paid | Examination procedure | 30.09.2013 | Examination requested [2014/05] | 29.06.2015 | Amendment by applicant (claims and/or description) | 30.10.2015 | Despatch of a communication from the examining division (Time limit: M06) | 05.05.2016 | Reply to a communication from the examining division | 19.05.2016 | Despatch of a communication from the examining division (Time limit: M06) | 15.11.2016 | Reply to a communication from the examining division | 19.01.2017 | Despatch of a communication from the examining division (Time limit: M04) | 15.05.2017 | Reply to a communication from the examining division | 22.09.2017 | Communication of intention to grant the patent | 22.01.2018 | Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO | 22.01.2018 | Fee for grant paid | 22.01.2018 | Fee for publishing/printing paid | 07.03.2018 | Communication of intention to grant the patent | 04.04.2018 | Receipt of the translation of the claim(s) | Divisional application(s) | EP18172179.6 / EP3385388 | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 30.10.2015 | Opposition(s) | 19.02.2019 | No opposition filed within time limit [2019/17] | Fees paid | Renewal fee | 12.03.2014 | Renewal fee patent year 03 | 10.03.2015 | Renewal fee patent year 04 | 10.03.2016 | Renewal fee patent year 05 | 10.03.2017 | Renewal fee patent year 06 | 13.03.2018 | Renewal fee patent year 07 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 22.03.2012 | AL | 16.05.2018 | AT | 16.05.2018 | CY | 16.05.2018 | CZ | 16.05.2018 | DK | 16.05.2018 | EE | 16.05.2018 | ES | 16.05.2018 | FI | 16.05.2018 | HR | 16.05.2018 | IT | 16.05.2018 | LT | 16.05.2018 | LV | 16.05.2018 | MC | 16.05.2018 | MK | 16.05.2018 | PL | 16.05.2018 | RO | 16.05.2018 | RS | 16.05.2018 | SE | 16.05.2018 | SI | 16.05.2018 | SK | 16.05.2018 | SM | 16.05.2018 | TR | 16.05.2018 | BG | 16.08.2018 | NO | 16.08.2018 | GR | 17.08.2018 | IS | 16.09.2018 | PT | 17.09.2018 | [2022/31] |
Former [2021/32] | HU | 22.03.2012 | |
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NO | 16.08.2018 | Documents cited: | Search | [X]WO2007093848 (AFFINIUM PHARM INC [CA], et al) [X] 13,14* figure 10A *; | [Y] - XUEFENG LU ET AL, "Overproduction of free fatty acids in E. coli: Implications for biodiesel production", METABOLIC ENGINEERING, (20081101), vol. 10, no. 6, doi:10.1016/j.ymben.2008.08.006, ISSN 1096-7176, pages 333 - 339, XP055100754 [Y] 1-12,15 * the whole document * * figure 1 * DOI: http://dx.doi.org/10.1016/j.ymben.2008.08.006 | [Y] - XIN MENG ET AL, "Increasing fatty acid production inby simulating the lipid accumulation of oleaginous microorganisms", JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY ; OFFICIAL JOURNAL OF THE SOCIETY FOR INDUSTRIAL MICROBIOLOGY, SPRINGER, BERLIN, DE, (20101026), vol. 38, no. 8, doi:10.1007/S10295-010-0861-Z, ISSN 1476-5535, pages 919 - 925, XP019928933 [Y] 1-12,15 * the whole document * DOI: http://dx.doi.org/10.1007/s10295-010-0861-z | International search | [X] - ZHA ET AL., "Improving cellular malonyl-CoA level in Escherichia coli via metabolic engineering", METAB..ENG., (200905), vol. 11, no. 3, pages 192 - 198, XP026034671 DOI: http://dx.doi.org/10.1016/j.ymben.2009.01.005 | [A] - FOWLER ET AL., "Increased Malonyl Coenzyme A Biosynthesis by Tuning the Escherichia coli Metabolic Network and Its Application to Flavanone Production", APPL. ENVIRON. MICROBIOL., (200909), vol. 75, no. 18, pages 5831 - 5839, XP055003952 DOI: http://dx.doi.org/10.1128/AEM.00270-09 | by applicant | US2469701 | US2798053 | US3687885 | US3891591 | US3904685 | US3915921 | US4268641 | US4301266 | US4666983 | US4685915 | US4708997 | US4734478 | US4857610 | US4985518 | US5009653 | US5093472 | US5135677 | US5145906 | US5180798 | US5331059 | US5342899 | US5350799 | US5426199 | US5470928 | US5510307 | US5558656 | US5817870 | US5827255 | US6355412 | WO0242418 | US6509156 | US6534679 | US6593116 | US6709919 | US2005222458 | US6960455 | US2007031918 | US7186856 | US2007219390 | US2008274523 | US2009076297 | US2009111151 | WO2010011874 | US7678869 | US2010291644 | US2011171702 | - BELLION ET AL., Microb. Growth Cl Compd. (Int. Symp.), INTERCEPT, (1993), pages 415 - 32 | - SULTER ET AL., ARCH. MICROBIOL., (1990), vol. 153, pages 485 - 489 | - B. ALBERTS ET AL., Molecular Biology of the Cell, 3rd Ed.,, GARLAND PUBLISHING, (1994), pages 42 - 45,66-74 | - D. L. NELSON; M. M. COX, Principles of Biochemistry 3rd Ed.,, WORTH PUBLISHERS, (2000), pages 527 - 658 | - L. STRYER, Biochemistry, 4th ed.,, W. H. FREEMAN AND CO., (1995), pages 463 - 650 | - DESHPANDE, MUKUND V., APPL. BIOCHEM. BIOTECHNOL., (1992), vol. 36, page 227 | - J. E. BAILEY; D. F. 01 LIS, Biochemical Engineering Fundamentals, 2nd ed, MCGRAW HILL, (1986), pages 533 - 657 | - BOWIE, J. U. ET AL., "Deciphering the Message in Protein Sequences: Tolerance to Amino Acid Substitutions", SCIENCE, (1990), vol. 247, doi:doi:10.1126/science.2315699, pages 1306 - 1310, XP002939052 DOI: http://dx.doi.org/10.1126/science.2315699 | - BRUTLAG ET AL., COMP. APP. BIOSCI., (1990), vol. 6, pages 237 - 245 | - Laboratory Manual Third Edition, COLD SPRING HARBOR LABORATORY PRESS, (2001), vol. 1-3 | - EPPINK ET AL., J MOL. BIOL., (1999), vol. 292, no. 1, pages 87 - 96 | - HALL; TOMSETT, MICROBIOLOGY, (2000), vol. 146, pages 1399 - 406 | - DOHR ET AL., PROC. NATL. ACAD. SCI., (2001), vol. 98, no. 1, pages 81 - 86 | - RICHARD J. HEATH; CHARLES 0. ROCK, "Enoyl-Acyl Carrier Protein (fabl) Plays a Determinant Role in Completing Cycles of Fatty Acid Elongation in Escherichia coli", J. BIOL. CHEM., (1995), vol. 270, no. 44, pages 26538 - 26543, XP001319003 | - MICROBIOLOGICAL REVIEWS, (199309), vol. 57, no. 3, pages 522 - 542 | - K. MAGNUSON ET AL., Regulation of Fatty Acid Biosynthesis in Escherichia coli, AMERICAN SOCIETY FOR MICROBIOLOGY | - W. ZHA ET AL., "Improving cellular malonyl-CoA level in Escherichia coli via metabolic engineering", METABOLIC ENGINEERING, (2009), vol. 11, doi:doi:10.1016/j.ymben.2009.01.005, pages 192 - 198, XP026034671 DOI: http://dx.doi.org/10.1016/j.ymben.2009.01.005 | - BEGUIN, P; AUBERT, J-P, FEMS MICROBIAL. REV., (1994), vol. 13, pages 25 - 58 | - OHIMA, K. ET AL., BIOTECHNOL. GENET. ENG. REV., (1997), vol. 14, page 365414 | - LEE ET AL., CELL, (2006), vol. 126, pages 691 - 699 | - CRONAN, CELL, (2006), page 126 | - OKAMURA ET AL., PNAS, (2010), vol. 107, page 25 | - JOONG KYUN KIM ET AL., "Extractive Recovery of Products from Fermentation Broths", BIOTECHNOL. BIOPROCESS ENG., (1999), doi:doi:10.1007/BF02931905, pages 1 - 11, XP002725590 DOI: http://dx.doi.org/10.1007/BF02931905 | - LAMBERT ET AL., AEM, vol. 73, no. 4, pages 1126 - 1135 | - SAMBROOK; RUSSELL, Molecular Cloning: A Laboratory Manual, Third Edition, COLD SPRING HARBOR LABORATORY PRESS, (2001), vol. 1-3 | - COWAN, P.J. ET AL., J. BACTERIOL., (1991), vol. 173, pages 7464 - 7470 | - "Membrane Separations in the Recovery of Biofuels and Biochemicals - An Update Review", STEPHEN A. LEEPER, Separation and Purification Technology, MARCEL DEKKER, (1992), pages 99 - 194 | US20090246141 |