blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register Resource Book
European Patent Register – pocket guide
FAQ - European Patent Register
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP2688575

EP2688575 - LITHIUM COMPOSITIONS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  27.01.2017
Database last updated on 18.10.2024
Most recent event   Tooltip12.10.2018Lapse of the patent in a contracting state
New state(s): AL		published on 14.11.2018  [2018/46]
Applicant(s)For all designated states
University of South Florida
Division of Patents and Licensing 3802 Spectrum Blvd., Suite 100
Tampa, FL 33612 / US
[2014/05]
Inventor(s)01 / ZAWOROTKO, Michael J.
4202 East Fowler Avenue
Tampa Florida 33620 / US
02 / SHYTLE, Roland D.
4202 East Fowler Avenue
Tampa Florida 33620 / US
03 / ONG, Tien Teng
4202 East Fowler Avenue
Tampa Florida 33620 / US
04 / KAVURU, Padmini
4202 East Fowler Avenue
Tampa Florida 33620 / US
05 / CANTWELL, Ryan N.
4202 East Fowler Avenue
Tampa Florida 33620 / US
06 / NGUYEN, Tranhha
4202 East Fowler Avenue
Tampa Florida 33620 / US
07 / SMITH, Adam John
4202 East Fowler Avenue
Tampa Florida 33620 / US
 [2014/05]
Representative(s)Smaggasgale, Gillian Helen
WP Thompson
138 Fetter Lane
London EC4A 1BT / GB
[N/P]
Former [2014/05]Smaggasgale, Gillian Helen
WP Thompson
55 Drury Lane
London WC2B 5SQ / GB
Application number, filing date12760816.426.03.2012
[2016/12]
WO2012US30586
Priority number, dateUS201161467272P24.03.2011         Original published format: US 201161467272 P
[2014/05]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2012129568
Date:27.09.2012
Language:EN
[2012/39]
Type: A2 Application without search report 
No.:EP2688575
Date:29.01.2014
Language:EN
The application published by WIPO in one of the EPO official languages on 27.09.2012 takes the place of the publication of the European patent application.
[2014/05]
Type: B1 Patent specification 
No.:EP2688575
Date:23.03.2016
Language:EN
[2016/12]
Search report(s)International search report - published on:KR22.11.2012
(Supplementary) European search report - dispatched on:EP05.08.2014
ClassificationIPC:A61K33/14, A61K33/10, A61K9/16, A61K9/20, A61K9/48, A61K9/08, A61K45/06, A61K33/00, A61K47/18, A61K47/22, A61K9/14
[2015/41]
CPC:
A61K33/14 (EP,US); A61K33/00 (EP,US); A61K45/06 (EP,US);
A61K47/22 (US); A61P25/20 (EP); A61P25/22 (EP);
A61P25/24 (EP); A61K2300/00 (US); A61K9/145 (EP,US) (-)
C-Set:
A61K33/00, A61K2300/00 (EP);
A61K33/14, A61K2300/00 (EP)
Former IPC [2014/36]A61K33/14, A61K33/10, A61K9/16, A61K9/20, A61K9/48, A61K9/08, A61K45/06, A61K33/00
Former IPC [2014/05]A61K33/14, A61K33/10, A61K9/16, A61K9/20, A61K9/48
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2014/05]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:LITHIUMZUSAMMENSETZUNGEN[2014/05]
English:LITHIUM COMPOSITIONS[2014/05]
French:COMPOSITIONS À BASE DE LITHIUM[2014/05]
Entry into regional phase18.09.2013National basic fee paid 
18.09.2013Search fee paid 
18.09.2013Designation fee(s) paid 
18.09.2013Examination fee paid 
Examination procedure18.09.2013Examination requested  [2014/05]
27.02.2015Amendment by applicant (claims and/or description)
08.05.2015Despatch of a communication from the examining division (Time limit: M04)
21.08.2015Reply to a communication from the examining division
21.10.2015Communication of intention to grant the patent
02.02.2016Fee for grant paid
02.02.2016Fee for publishing/printing paid
02.02.2016Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  08.05.2015
Opposition(s)02.01.2017No opposition filed within time limit [2017/09]
Fees paidRenewal fee
27.03.2014Renewal fee patent year 03
27.03.2015Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU26.03.2012
AL23.03.2016
AT23.03.2016
BE23.03.2016
CY23.03.2016
CZ23.03.2016
DK23.03.2016
EE23.03.2016
ES23.03.2016
FI23.03.2016
HR23.03.2016
IT23.03.2016
LT23.03.2016
LV23.03.2016
MC23.03.2016
MK23.03.2016
NL23.03.2016
PL23.03.2016
RO23.03.2016
RS23.03.2016
SE23.03.2016
SI23.03.2016
SK23.03.2016
SM23.03.2016
TR23.03.2016
LU26.03.2016
CH31.03.2016
LI31.03.2016
MT31.03.2016
FR23.05.2016
BG23.06.2016
NO23.06.2016
GR24.06.2016
IS23.07.2016
PT25.07.2016
DE01.10.2016
[2018/46]
Former [2018/31]HU26.03.2012
AT23.03.2016
BE23.03.2016
CY23.03.2016
CZ23.03.2016
DK23.03.2016
EE23.03.2016
ES23.03.2016
FI23.03.2016
HR23.03.2016
IT23.03.2016
LT23.03.2016
LV23.03.2016
MC23.03.2016
MK23.03.2016
NL23.03.2016
PL23.03.2016
RO23.03.2016
RS23.03.2016
SE23.03.2016
SI23.03.2016
SK23.03.2016
SM23.03.2016
TR23.03.2016
LU26.03.2016
CH31.03.2016
LI31.03.2016
MT31.03.2016
FR23.05.2016
BG23.06.2016
NO23.06.2016
GR24.06.2016
IS23.07.2016
PT25.07.2016
DE01.10.2016
Former [2018/29]HU26.03.2012
AT23.03.2016
BE23.03.2016
CY23.03.2016
CZ23.03.2016
DK23.03.2016
EE23.03.2016
ES23.03.2016
FI23.03.2016
HR23.03.2016
IT23.03.2016
LT23.03.2016
LV23.03.2016
MC23.03.2016
MK23.03.2016
MT23.03.2016
NL23.03.2016
PL23.03.2016
RO23.03.2016
RS23.03.2016
SE23.03.2016
SI23.03.2016
SK23.03.2016
SM23.03.2016
TR23.03.2016
LU26.03.2016
CH31.03.2016
LI31.03.2016
FR23.05.2016
BG23.06.2016
NO23.06.2016
GR24.06.2016
IS23.07.2016
PT25.07.2016
DE01.10.2016
Former [2018/28]HU26.03.2012
AT23.03.2016
BE23.03.2016
CY23.03.2016
CZ23.03.2016
DK23.03.2016
EE23.03.2016
ES23.03.2016
FI23.03.2016
HR23.03.2016
IT23.03.2016
LT23.03.2016
LV23.03.2016
MC23.03.2016
MK23.03.2016
MT23.03.2016
NL23.03.2016
PL23.03.2016
RO23.03.2016
RS23.03.2016
SE23.03.2016
SI23.03.2016
SK23.03.2016
SM23.03.2016
CH31.03.2016
LI31.03.2016
FR23.05.2016
BG23.06.2016
NO23.06.2016
GR24.06.2016
IS23.07.2016
PT25.07.2016
DE01.10.2016
Former [2017/47]AT23.03.2016
BE23.03.2016
CZ23.03.2016
DK23.03.2016
EE23.03.2016
ES23.03.2016
FI23.03.2016
HR23.03.2016
IT23.03.2016
LT23.03.2016
LV23.03.2016
MT23.03.2016
NL23.03.2016
PL23.03.2016
RO23.03.2016
RS23.03.2016
SE23.03.2016
SI23.03.2016
SK23.03.2016
SM23.03.2016
CH31.03.2016
LI31.03.2016
FR23.05.2016
BG23.06.2016
NO23.06.2016
GR24.06.2016
IS23.07.2016
PT25.07.2016
DE01.10.2016
Former [2017/26]AT23.03.2016
BE23.03.2016
CZ23.03.2016
DK23.03.2016
EE23.03.2016
ES23.03.2016
FI23.03.2016
HR23.03.2016
IT23.03.2016
LT23.03.2016
LV23.03.2016
NL23.03.2016
PL23.03.2016
RO23.03.2016
RS23.03.2016
SE23.03.2016
SI23.03.2016
SK23.03.2016
SM23.03.2016
CH31.03.2016
LI31.03.2016
FR23.05.2016
BG23.06.2016
NO23.06.2016
GR24.06.2016
IS23.07.2016
PT25.07.2016
DE01.10.2016
Former [2017/19]AT23.03.2016
BE23.03.2016
CZ23.03.2016
DK23.03.2016
EE23.03.2016
ES23.03.2016
FI23.03.2016
HR23.03.2016
IT23.03.2016
LT23.03.2016
LV23.03.2016
NL23.03.2016
PL23.03.2016
RO23.03.2016
RS23.03.2016
SE23.03.2016
SK23.03.2016
SM23.03.2016
CH31.03.2016
LI31.03.2016
BG23.06.2016
NO23.06.2016
GR24.06.2016
IS23.07.2016
PT25.07.2016
DE01.10.2016
Former [2017/08]AT23.03.2016
BE23.03.2016
CZ23.03.2016
DK23.03.2016
EE23.03.2016
ES23.03.2016
FI23.03.2016
HR23.03.2016
IT23.03.2016
LT23.03.2016
LV23.03.2016
NL23.03.2016
PL23.03.2016
RO23.03.2016
RS23.03.2016
SE23.03.2016
SK23.03.2016
SM23.03.2016
CH31.03.2016
LI31.03.2016
NO23.06.2016
GR24.06.2016
IS23.07.2016
PT25.07.2016
DE01.10.2016
Former [2017/07]AT23.03.2016
BE23.03.2016
CZ23.03.2016
DK23.03.2016
EE23.03.2016
ES23.03.2016
FI23.03.2016
HR23.03.2016
IT23.03.2016
LT23.03.2016
LV23.03.2016
NL23.03.2016
PL23.03.2016
RO23.03.2016
RS23.03.2016
SE23.03.2016
SK23.03.2016
SM23.03.2016
CH31.03.2016
LI31.03.2016
NO23.06.2016
GR24.06.2016
IS23.07.2016
PT25.07.2016
Former [2017/03]AT23.03.2016
BE23.03.2016
CZ23.03.2016
EE23.03.2016
ES23.03.2016
FI23.03.2016
HR23.03.2016
IT23.03.2016
LT23.03.2016
LV23.03.2016
NL23.03.2016
PL23.03.2016
RO23.03.2016
RS23.03.2016
SE23.03.2016
SK23.03.2016
SM23.03.2016
NO23.06.2016
GR24.06.2016
IS23.07.2016
PT25.07.2016
Former [2016/51]AT23.03.2016
CZ23.03.2016
EE23.03.2016
ES23.03.2016
FI23.03.2016
HR23.03.2016
LT23.03.2016
LV23.03.2016
NL23.03.2016
PL23.03.2016
RO23.03.2016
RS23.03.2016
SE23.03.2016
SK23.03.2016
SM23.03.2016
BE31.03.2016
NO23.06.2016
GR24.06.2016
IS23.07.2016
PT25.07.2016
Former [2016/50]AT23.03.2016
CZ23.03.2016
EE23.03.2016
ES23.03.2016
FI23.03.2016
HR23.03.2016
LT23.03.2016
LV23.03.2016
NL23.03.2016
PL23.03.2016
RO23.03.2016
RS23.03.2016
SE23.03.2016
SK23.03.2016
SM23.03.2016
BE31.03.2016
NO23.06.2016
GR24.06.2016
IS23.07.2016
Former [2016/49]EE23.03.2016
FI23.03.2016
HR23.03.2016
LT23.03.2016
LV23.03.2016
NL23.03.2016
PL23.03.2016
RS23.03.2016
SE23.03.2016
BE31.03.2016
NO23.06.2016
GR24.06.2016
IS23.07.2016
Former [2016/48]FI23.03.2016
HR23.03.2016
LT23.03.2016
LV23.03.2016
NL23.03.2016
RS23.03.2016
SE23.03.2016
BE31.03.2016
NO23.06.2016
GR24.06.2016
IS23.07.2016
Former [2016/40]FI23.03.2016
HR23.03.2016
LT23.03.2016
LV23.03.2016
NL23.03.2016
RS23.03.2016
SE23.03.2016
BE31.03.2016
NO23.06.2016
GR24.06.2016
Former [2016/39]FI23.03.2016
HR23.03.2016
LT23.03.2016
LV23.03.2016
RS23.03.2016
SE23.03.2016
BE31.03.2016
NO23.06.2016
GR24.06.2016
Former [2016/36]FI23.03.2016
HR23.03.2016
LT23.03.2016
BE31.03.2016
NO23.06.2016
GR24.06.2016
Former [2016/35]FI23.03.2016
HR23.03.2016
NO23.06.2016
GR24.06.2016
Documents cited:Search[X]  - TOM CHLUPAT ET AL, "Structure and properties of lithium-butyl amidinates", JOURNAL OF ORGANOMETALLIC CHEMISTRY, ELSEVIER-SEQUOIA S.A. LAUSANNE, CH, vol. 696, no. 11, doi:10.1016/J.JORGANCHEM.2011.02.026, ISSN 0022-328X, (20110222), pages 2346 - 2354, (20110302), XP028201038 [X] 14 * abstract * * page 2348, column 2, paragraph 2 *

DOI:   http://dx.doi.org/10.1016/j.jorganchem.2011.02.026
 [A]  - P. KAVURU ET AL., "Hierarchy of Supramolecular Synthons: Persistent Hydrogen Bonds Between Carboxylates and Weakly Acidic Hydroxyl Moieties in Cocrystals of Zwitterions", CRYSTAL GROWTH & DESIGN, (20100707), vol. 10, no. 8, doi:10.1021/cg100484a, pages 3568 - 3584, XP002727753 [A] 1-15 * abstract *

DOI:   http://dx.doi.org/10.1021/cg100484a
 [A]  - H.D. CLARKE ET AL., "Structure-Stability Relationships in Cocrystal Hydrates: Does the Promiscuity of Water Make Crystalline Hydrates the Nemesis of Crystal Engineering?", CRYSTAL GROWTH & DESIGN, (20100330), vol. 10, no. 5, doi:10.1021/cg901345u, pages 2152 - 2167, XP002727754 [A] 1-15 * abstract *

DOI:   http://dx.doi.org/10.1021/cg901345u
 [A]  - SHAN N ET AL, "The role of cocrystals in pharmaceutical science", DRUG DISCOVERY TODAY, ELSEVIER, RAHWAY, NJ, US, vol. 13, no. 9-10, doi:10.1016/J.DRUDIS.2008.03.004, ISSN 1359-6446, (20080501), pages 440 - 446, (20080422), XP022649919 [A] 1-15 * abstract *

DOI:   http://dx.doi.org/10.1016/j.drudis.2008.03.004
 [XP]  - SHYTLE R D ET AL, "A Novel Lithium Cocrystal With Improved Oral Bioavailability and Targeted Brain Delivery", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (2012), Database accession no. PREV201200490850, XP002727755 [XP] 1-13 * abstract *
    [ ] - CELL TRANSPLANTATION, 19TH ANNUAL MEETING OF THE AMERICAN-SOCIETY-FOR-NEURAL-THERAPY-AND-REPAIR; CLEARWATER BEACH, FL, USA; APRIL 26 -28, 2012, (2012), vol. 21, no. 4, ISSN 0963-6897(print), page 792
 [XP]  - SMITH ADAM J ET AL, "Improving lithium therapeutics by crystal engineering of novel ionic cocrystals.", MOLECULAR PHARMACEUTICS 2 DEC 2013, (20131202), vol. 10, no. 12, ISSN 1543-8392, pages 4728 - 4738, XP002727756 [XP] 1-13 * the whole document *

DOI:   http://dx.doi.org/10.1021/mp400571a
 [XP]  - ONG TIEN TENG ET AL, "2:1 cocrystals of homochiral and achiral amino acid zwitterions with Li+ salts: water-stable zeolitic and diamondoid metal-organic materials.", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 22 JUN 2011, (20110622), vol. 133, no. 24, ISSN 1520-5126, pages 9224 - 9227, XP002727757 [XP] 14,15 * the whole document *

DOI:   http://dx.doi.org/10.1021/ja203002w
International search[A]US2004176335  (CHILDS SCOTT L [US]);
 [A]WO2004078163  (TRANSFORM PHARMACEUTICALS INC [US], et al);
 [A]US2010204204  (ZAWOROTKO MICHAEL [US], et al);
 [X]  - T. UMA DEVI ET AL., "Synthesis, crystal growth and characterization of L-proline lithium chloride monohydrate: a new semiorganic nonlinear optical material", CRYSTAL GROWTH & DESIGN, (2009), vol. 9, no. 3, pages 1370 - 1374, XP055123496

DOI:   http://dx.doi.org/10.1021/cg800589m
 [X]  - J. BARAN ET AL., "Bis(glycine) lithium nitrate - a new non-centrosymmetric crystal: X-ray structure, vibrational spectra and DSC investigations", JOURNAL OF MOLECULAR STRUCTURE, (2009), vol. 927, no. 1/3, pages 43 - 53, XP026119909

DOI:   http://dx.doi.org/10.1016/j.molstruc.2008.11.049
by applicant   - TOM CHLUPAT ET AL., "Structure and properties of lithium-butyl amidinates", JOURNAL OF ORGANOMETALLIC CHEMISTRY, (20110222), vol. 696, no. 11, doi:doi:10.1016/j.jorganchem.2011.02.026, pages 2346 - 2354, XP028201038

DOI:   http://dx.doi.org/10.1016/j.jorganchem.2011.02.026
    - T. UMA DEVI ET AL., "Synthesis, Crystal growth and characterization of L-proline lithium chloride monohydrate: a new semiorganic nonlinear optical material", CRYSTAL GROWTH & DESIGN, (2009), vol. 9, no. 3, doi:doi:10.1021/cg800589m, pages 1370 - 1374, XP055123496

DOI:   http://dx.doi.org/10.1021/cg800589m
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.