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Extract from the Register of European Patents

EP About this file: EP2691512

EP2691512 - ENRICHED POPULATIONS OF CARDIOMYOCYTE LINEAGE CELLS FROM PLURIPOTENT STEM CELLS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  06.03.2020
Database last updated on 20.05.2024
FormerThe patent has been granted
Status updated on  29.03.2019
FormerGrant of patent is intended
Status updated on  04.12.2018
FormerExamination is in progress
Status updated on  14.11.2016
Most recent event   Tooltip08.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 10.08.2022  [2022/32]
Applicant(s)For all designated states
Asterias Biotherapeutics, Inc.
6300 Dumbarton Circle
Fremont CA 94555 / US
[2019/16]
Former [2014/24]For all designated states
Asterias Biotherapeutics, Inc.
230 Constitution Drive
Menlo Park, CA 94025 / US
Former [2014/06]For all designated states
GERON CORPORATION
149 Commonwealth Drive
Menlo Park, CA 94025 / US
Inventor(s)01 / O'SULLIVAN, Christopher
986 Shoal Drive
San Mateo, CA 94404 / US
02 / NISHIMOTO, Kevin
225 9th Street 305
San Mateo, CA 94401 / US
03 / REDDY, Anita
411 Old Ranch Ct.
San Ramon, CA 94582 / US
 [2014/06]
Representative(s)Bassil, Nicholas Charles, et al
Kilburn & Strode LLP
Lacon London
84 Theobalds Road
London WC1X 8NL / GB
[2019/18]
Former [2014/06]Bassil, Nicholas Charles, et al
Kilburn & Strode LLP
20 Red Lion Street
London WC1R 4PJ / GB
Application number, filing date12763669.428.03.2012
[2019/18]
WO2012US30799
Priority number, dateUS201161468952P29.03.2011         Original published format: US 201161468952 P
[2014/06]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2012135253
Date:04.10.2012
Language:EN
[2012/40]
Type: A1 Application with search report 
No.:EP2691512
Date:05.02.2014
Language:EN
The application published by WIPO in one of the EPO official languages on 04.10.2012 takes the place of the publication of the European patent application.
[2014/06]
Type: B1 Patent specification 
No.:EP2691512
Date:01.05.2019
Language:EN
[2019/18]
Search report(s)International search report - published on:US04.10.2012
(Supplementary) European search report - dispatched on:EP23.01.2014
ClassificationIPC:C12N5/077, C12N5/0775, C12N13/00, C12N5/00
[2018/48]
CPC:
C12N5/0657 (EP,US); C12N13/00 (US); C12N5/0081 (EP,US);
C12N5/0662 (EP,US); C12N2501/998 (US); C12N2506/02 (EP,US)
Former IPC [2014/06]C12N5/00
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2014/06]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:ANGEREICHERTE POPULATIONEN VON HERZMUSKELZELLEN AUS PLURIPOTENTEN STAMMZELLEN[2014/06]
English:ENRICHED POPULATIONS OF CARDIOMYOCYTE LINEAGE CELLS FROM PLURIPOTENT STEM CELLS[2014/06]
French:POPULATIONS ENRICHIES DE CELLULES DE LIGNÉE CARDIOMYOCYTAIRE ISSUES DE CELLULES SOUCHES PLURIPOTENTES[2014/06]
Entry into regional phase28.10.2013National basic fee paid 
28.10.2013Search fee paid 
28.10.2013Designation fee(s) paid 
28.10.2013Examination fee paid 
Examination procedure28.10.2013Examination requested  [2014/06]
13.08.2014Amendment by applicant (claims and/or description)
17.02.2015Despatch of a communication from the examining division (Time limit: M06)
03.12.2015Reply to a communication from the examining division
08.07.2016Despatch of a communication from the examining division (Time limit: M06)
14.02.2017Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
24.04.2017Reply to a communication from the examining division
16.11.2017Despatch of a communication from the examining division (Time limit: M06)
17.05.2018Reply to a communication from the examining division
05.12.2018Communication of intention to grant the patent
21.03.2019Fee for grant paid
21.03.2019Fee for publishing/printing paid
21.03.2019Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  17.02.2015
Opposition(s)04.02.2020No opposition filed within time limit [2020/15]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
24.04.2017Request for further processing filed
24.04.2017Full payment received (date of receipt of payment)
Request granted
16.05.2017Decision despatched
The application is deemed to be withdrawn due to failure to reply to the examination report
03.12.2015Request for further processing filed
03.12.2015Full payment received (date of receipt of payment)
Request granted
14.12.2015Decision despatched
Fees paidRenewal fee
08.09.2014Renewal fee patent year 03
10.03.2015Renewal fee patent year 04
30.03.2016Renewal fee patent year 05
27.03.2017Renewal fee patent year 06
26.03.2018Renewal fee patent year 07
13.03.2019Renewal fee patent year 08
Penalty fee
Additional fee for renewal fee
31.03.201403   M06   Fee paid on   08.09.2014
Opt-out from the exclusive  Tooltip
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU28.03.2012
AL01.05.2019
AT01.05.2019
CY01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
MC01.05.2019
MK01.05.2019
MT01.05.2019
NL01.05.2019
PL01.05.2019
RO01.05.2019
RS01.05.2019
SE01.05.2019
SI01.05.2019
SK01.05.2019
SM01.05.2019
TR01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
[2022/32]
Former [2022/27]HU28.03.2012
AL01.05.2019
AT01.05.2019
CY01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
MC01.05.2019
MT01.05.2019
NL01.05.2019
PL01.05.2019
RO01.05.2019
RS01.05.2019
SE01.05.2019
SI01.05.2019
SK01.05.2019
SM01.05.2019
TR01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
Former [2020/49]AL01.05.2019
AT01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
MC01.05.2019
NL01.05.2019
PL01.05.2019
RO01.05.2019
RS01.05.2019
SE01.05.2019
SI01.05.2019
SK01.05.2019
SM01.05.2019
TR01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
Former [2020/25]AL01.05.2019
AT01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
PL01.05.2019
RO01.05.2019
RS01.05.2019
SE01.05.2019
SI01.05.2019
SK01.05.2019
SM01.05.2019
TR01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
Former [2020/17]AL01.05.2019
AT01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
RO01.05.2019
RS01.05.2019
SE01.05.2019
SK01.05.2019
SM01.05.2019
TR01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
Former [2020/14]AL01.05.2019
AT01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
RO01.05.2019
RS01.05.2019
SE01.05.2019
SK01.05.2019
SM01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
Former [2020/12]AL01.05.2019
AT01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
RO01.05.2019
RS01.05.2019
SE01.05.2019
SK01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
Former [2020/11]AL01.05.2019
AT01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
RO01.05.2019
RS01.05.2019
SE01.05.2019
SK01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
Former [2020/10]AL01.05.2019
AT01.05.2019
CZ01.05.2019
DK01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
RO01.05.2019
RS01.05.2019
SE01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
Former [2020/09]AL01.05.2019
CZ01.05.2019
DK01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
RS01.05.2019
SE01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
Former [2020/04]AL01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
RS01.05.2019
SE01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
Former [2019/51]AL01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
RS01.05.2019
SE01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
PT01.09.2019
Former [2019/50]AL01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
RS01.05.2019
SE01.05.2019
NO01.08.2019
GR02.08.2019
PT01.09.2019
Former [2019/49]AL01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
LT01.05.2019
NL01.05.2019
SE01.05.2019
NO01.08.2019
PT01.09.2019
Former [2019/48]ES01.05.2019
FI01.05.2019
LT01.05.2019
SE01.05.2019
NO01.08.2019
PT01.09.2019
Former [2019/47]ES01.05.2019
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NO01.08.2019
Documents cited:Search[Y]WO2008048931  (CELULA INC [US], et al) [Y] 1-18 * claims 1,18 *;
 [Y]WO2009017460  (ES CELL INT PTE LTD [SG], et al) [Y] 1-18 * claims 1,4,7 *;
 [XP]WO2012024782  (UNIV HEALTH NETWORK [CA], et al) [XP] 1-18 * claims 1,16,17,30 *
 [Y]  - MICHAEL A LAFLAMME ET AL, "Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts", NATURE BIOTECHNOLOGY, (20070901), vol. 25, no. 9, doi:10.1038/nbt1327, ISSN 1087-0156, pages 1015 - 1024, XP055008206 [Y] 1-18 * page 1021, column 2, paragraph 2 *

DOI:   http://dx.doi.org/10.1038/nbt1327
 [Y]  - FLAVIUS C PASCUT ET AL, "Noninvasive Detection and Imaging of Molecular Markers in Live Cardiomyocytes Derived from Human Embryonic Stem Cells", BIOPHYSICAL JOURNAL, CELL PRESS, US, vol. 100, no. 1, doi:10.1016/J.BPJ.2010.11.043, ISSN 0006-3495, (20101123), pages 251 - 259, (20101206), XP028153686 [Y] 1-18 * page 252, column 2, paragraph 3 *

DOI:   http://dx.doi.org/10.1016/j.bpj.2010.11.043
 [Y]  - HONDA M ET AL, "N-cadherin is a useful marker for the progenitor of cardiomyocytes differentiated from mouse ES cells in serum-free condition", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 351, no. 4, doi:10.1016/J.BBRC.2006.10.126, ISSN 0006-291X, (20061229), pages 877 - 882, (20061229), XP024925771 [Y] 1-18 * page 878, column 2, paragraph 2; figures 1,3 *

DOI:   http://dx.doi.org/10.1016/j.bbrc.2006.10.126
 [Y]  - CHUNHUI XU ET AL, "Efficient generation and cryopreservation of cardiomyocytes derived from human embryonic stem cells", REGENERATIVE MEDICINE, (20110101), vol. 6, no. 1, doi:10.2217/rme.10.91, ISSN 1746-0751, pages 53 - 66, XP055096219 [Y] 1-18 * page 3, paragraph 1 *

DOI:   http://dx.doi.org/10.2217/rme.10.91
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