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Extract from the Register of European Patents

EP About this file: EP2783214

EP2783214 - PROTEOMIC IDENTIFICATION OF ANTIBODIES [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  12.01.2018
Database last updated on 21.09.2024
FormerExamination is in progress
Status updated on  20.03.2017
Most recent event   Tooltip12.01.2018Application deemed to be withdrawnpublished on 14.02.2018  [2018/07]
Applicant(s)For all designated states
The Board of Regents of The University of Texas System
201 West 7th Street
Austin, TX 78701 / US
[2014/40]
Inventor(s)01 / LAVINDER, Jason
c/o The University of Texas at Austin
1 University Station C0800
Austin, TX 78712-6975 / US
02 / WINE, Yariv
c/o The University of Texas at Austin
1 University Station C0800
Austin, TX 78712-6975 / US
03 / BOUTZ, Danny
c/o The University of Texas at Austin
1 University Station C0800
Austin, TX 78712-6975 / US
04 / MARCOTTE, Edward
c/o The University of Texas at Austin
1 University Station C0800
Austin, TX 78712-6975 / US
05 / GEORGIOU, George
c/o The University of Texas at Austin
1 University Station C0800
Austin, TX 78712-6975 / US
 [2014/40]
Representative(s)Boult Wade Tennant LLP
Salisbury Square House
8 Salisbury Square
London EC4Y 8AP / GB
[N/P]
Former [2014/40]Callaghan, Dayle Anne
Rouse IP Limited
11th Floor, Exchange Tower
1 Harbour Exchange Square
London E14 9GE / GB
Application number, filing date12799408.523.11.2012
WO2012US66454
Priority number, dateUS201161563380P23.11.2011         Original published format: US 201161563380 P
[2014/40]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2013078455
Date:30.05.2013
Language:EN
[2013/22]
Type: A2 Application without search report 
No.:EP2783214
Date:01.10.2014
Language:EN
The application published by WIPO in one of the EPO official languages on 30.05.2013 takes the place of the publication of the European patent application.
[2014/40]
Search report(s)International search report - published on:EP31.10.2013
ClassificationIPC:G01N33/531, G01N33/68
[2014/40]
CPC:
G01N33/6857 (EP,US); C12Q1/6874 (US); G01N33/531 (EP,US);
G01N33/6848 (EP,US); G01N33/6854 (EP,US); C40B30/04 (US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2014/40]
TitleGerman:PROTEOMISCHER NACHWEIS VON ANTIKÖRPERN[2014/40]
English:PROTEOMIC IDENTIFICATION OF ANTIBODIES[2014/40]
French:IDENTIFICATION PROTÉOMIQUE D'ANTICORPS[2014/40]
Entry into regional phase23.05.2014National basic fee paid 
23.05.2014Designation fee(s) paid 
23.05.2014Examination fee paid 
Examination procedure23.05.2014Examination requested  [2014/40]
12.01.2015Amendment by applicant (claims and/or description)
05.02.2016Despatch of a communication from the examining division (Time limit: M06)
12.08.2016Reply to a communication from the examining division
07.03.2017Despatch of a communication from the examining division (Time limit: M06)
19.09.2017Application deemed to be withdrawn, date of legal effect  [2018/07]
12.10.2017Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2018/07]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  05.02.2016
Fees paidRenewal fee
22.10.2014Renewal fee patent year 03
10.11.2015Renewal fee patent year 04
10.11.2016Renewal fee patent year 05
13.11.2017Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[XP]WO2011146514  (UNIV TEXAS [US], et al) [XP] 1-24,48-57 * the whole document *;
 [I]  - REDDY SAI T ET AL, "Monoclonal antibodies isolated without screening by analyzing the variable-gene repertoire of plasma cells", NATURE BIOTECHNOLOGY, (201009), vol. 28, no. 9, ISSN 1087-0156, page 965, XP002693037 [I] 1-24,48-57 * abstract *

DOI:   http://dx.doi.org/10.1038/nbt.1673
 [I]  - FISCHER NICOLAS, "Sequencing antibody repertoires The next generation", MABS, (201101), vol. 3, no. 1, pages 17 - 20, XP002693038 [I] 1-24,48-57 * abstr, fig 1; p 19, col 1, para 1 *

DOI:   http://dx.doi.org/10.4161/mabs.3.1.14169
 [A]  - NAZABAL A ET AL, "Immunoassays with direct mass spectrometric detection", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, (20060601), vol. 78, no. 11, doi:10.1021/AC0519108, ISSN 0003-2700, pages 3562 - 3570, XP002438305 [A] 1-24,48-57 * the whole document *

DOI:   http://dx.doi.org/10.1021/ac0519108
 [Y]  - RAVETCH J V ET AL, "STRUCTURE OF THE HUMAN IMMUNOGLOBULIN MU LOCUS: CHARACTERIZATION OFEMBRYONIC AND REARRANGED J AND D GENES", CELL, CELL PRESS, US, (19811201), vol. 27, no. IT-02, doi:10.1016/0092-8674(81)90400-1, ISSN 0092-8674, pages 583 - 591, XP000925548 [Y] 25-47 * abstract *

DOI:   http://dx.doi.org/10.1016/0092-8674(81)90400-1
 [Y]  - WILLIS T G ET AL, "Rapid molecular cloning of rearrangements of the IGHJ locus using long-distance inverse polymerase chain reaction", BLOOD, (1997), vol. 90, no. 6, ISSN 0006-4971, pages 2456 - 2464, XP002701130 [Y] 25-47 * abstract *
 [XP]  - WAN CHEUNG CHEUNG ET AL, "A proteomics approach for the identification and cloning of monoclonal antibodies from serum", NATURE BIOTECHNOLOGY, (20120101), doi:10.1038/nbt.2167, ISSN 1087-0156, XP055026189 [XP] 1-24,48-57 * the whole document *

DOI:   http://dx.doi.org/10.1038/nbt.2167
 [XP]  - SHUJI SATO ET AL, "Proteomics-directed cloning of circulating antiviral human monoclonal antibodies", NATURE BIOTECHNOLOGY, (20121101), vol. 30, no. 11, doi:10.1038/nbt.2406, ISSN 1087-0156, pages 1039 - 1043, XP055054091 [XP] 1-24,48-57 * the whole document *

DOI:   http://dx.doi.org/10.1038/nbt.2406
 [XP]  - ALESSIO MAIOLICA ET AL, "Targeted proteome investigation via selected reaction monitoring mass spectrometry", JOURNAL OF PROTEOMICS, ELSEVIER, AMSTERDAM, NL, vol. 75, no. 12, doi:10.1016/J.JPROT.2012.04.048, ISSN 1874-3919, (20120429), pages 3495 - 3513, (20120508), XP028430290 [XP] 1-24,48-57 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.jprot.2012.04.048
 [T]  - Y. WINE ET AL, "Molecular deconvolution of the monoclonal antibodies that comprise the polyclonal serum response", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, (20130219), vol. 110, no. 8, doi:10.1073/pnas.1213737110, ISSN 0027-8424, pages 2993 - 2998, XP055054078

DOI:   http://dx.doi.org/10.1073/pnas.1213737110
 [T]  - BRANDON J DEKOSKY ET AL, "High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire", NATURE BIOTECHNOLOGY, (20130101), vol. 31, no. 2, doi:10.1038/nbt.2492, ISSN 1087-0156, pages 166 - 169, XP055054081

DOI:   http://dx.doi.org/10.1038/nbt.2492
 [IP]  - H. MOUQUET ET AL, "PNAS Plus: Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, (20121120), vol. 109, no. 47, doi:10.1073/pnas.1217207109, ISSN 0027-8424, pages E3268 - E3277, XP055068116 [IP] 1-57 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.1217207109
 [IP]  - IPPOLITO GREGORY C ET AL, "Antibody Repertoires in Humanized NOD-scid-IL2R gamma(null) Mice and Human B Cells Reveals Human-Like Diversification and Tolerance Checkpoints in the Mouse", PLOS ONE, (201204), vol. 7, no. 4, XP002701124 [IP] 1-57 * the whole document *

DOI:   http://dx.doi.org/10.1371/JOURNAL.PONE.0035497
by applicantEP0239400
 EP0171496
 EP0173494
 EP0194276
 WO8901782
 WO8901974
 WO8902465
 US8043621
    - BROWNING ET AL., NATURE, (1955), vol. 175, pages 570 - 575
    - CLACKSON ET AL., NATURE, (1991), vol. 352, pages 624 - 628
    - COBAUGH ET AL., J. MOL. BIOL., (2008), vol. 378, no. 3, pages 622 - 633
    - COX ET AL., PROTEIN SCI., (2007), vol. 16, pages 379 - 390
    - DE COSTA ET AL., J. PROTEOME RES., (2010), vol. 9, pages 2937 - 2945
    - DEKKER ET AL., ANALY. BIOANALYT. CHEM., (2011), vol. 399, pages 1081 - 1091
    - FELDHAUS ET AL., NAT. BIOTECHNOL., (2003), vol. 21, pages 163 - 170
    - FOX ET AL., METHODS MOL. BIOL., (2009), vol. 553, pages 79 - 108
    - GAO ET AL., NUCLEIC ACIDS RES., (2003), vol. 31, page E143
    - GIBSON ET AL., "Enzymatic assembly of DNA molecules up to several hundred kilobases", NAT. METHODS., (2009), vol. 6, doi:doi:10.1038/nmeth.1318, pages 343 - 345, XP055224105

DOI:   http://dx.doi.org/10.1038/nmeth.1318
    - HARLOW; LANE, Antibodies: A Laboratory Manual, COLD SPRING HARBOR LABORATORY, (1988), pages 346 - 348
    - HARVEY ET AL., PROC. NATL. ACAD. SCI. USA, (2004), vol. 101, pages 9193 - 9198
    - HAYHURST ET AL., J. IMMUNOL. METHODS, (2003), vol. 276, pages 185 - 196
    - HOOGENBOOM, NAT. BIOTECHNOL., (2005), vol. 23, pages 1105 - 1116
    - HOSSE ET AL., PROTEIN SCI., (2006), vol. 15, pages 14 - 27
    - HU ET AL., J. MASS. SPECTROM., (2005), vol. 40, pages 430 - 443
    - HUNT ET AL., PROC. NATL. ACAD. SCI. USA, (1986), vol. 83, pages 6233 - 6237
    - IPPOLITO ET AL., PLOS ONE, (2012), vol. 7, no. 4, page E35497
    - ISHIHAMA ET AL., MOL. CELL PROTEOMICS, (2005), vol. 4, pages 1265 - 1272
    - JACKSON ET AL., ADV. IMMUNOL., (2008), vol. 98, pages 151 - 224
    - JIN ET AL., NAT. MED., (2009), vol. 15, pages 1088 - 1092
    - KANTHA, J. MED., (1991), vol. 40, pages 35 - 39
    - KELLER ET AL., ANAL. CHEM., (2002), vol. 74, pages 5383 - 5392
    - KOHLER; MILSTEIN, NATURE, (1975), vol. 256, pages 495 - 497
    - KREBBER ET AL., J. IMMUNOL. METHODS, (1997), vol. 201, pages 35 - 55
    - KRETZSCHMAR; VON RUDEN, CURR. OPIN. BIOTECH., (2002), vol. 13, pages 598 - 602
    - KWAKKENBOS ET AL., NAT. MED., (2010), vol. 16, pages 123 - 128
    - LINK ET AL., NAT. BIOTECHNOL., (1999), vol. 17, pages 676 - 682
    - LIU ET AL., ANAL. CHEM., (2004), vol. 76, pages 4193 - 4201
    - LOVE ET AL., NAT. BIOTECHNOL., (2006), vol. 24, pages 703 - 707
    - LU ET AL., NAT. BIOTECHNOL., (2007), vol. 25, pages 117 - 124
    - MALMSTROEM ET AL., NATURE, (2009), vol. 460, pages 762 - U112
    - MALMSTROM ET AL., NATURE, (2009), vol. 460, no. 7256, pages 762 - 5
    - MARCOTTE, NAT. BIOTECHNOL., (2007), vol. 25, pages 755 - 757
    - MAZOR ET AL., J. IMMUNOL. METHODS, (2007), vol. 321, pages 41 - 59
    - MAZOR ET AL., NAT. BIOTECHNOL., (2007), vol. 25, pages 563 - 565
    - MEIJER ET AL., J MOLEC. BIOL., (2006), vol. 358, pages 764 - 772
    - NESVIZHSKII ET AL., ANAL. CHEM., (2003), vol. 75, pages 4646 - 4658
    - OLSEN ET AL., NAT. METHODS, (2007), vol. 4, pages 709 - 712
    - ONG; MANN, NAT. CHEM. BIOL., (2005), vol. 1, pages 252 - 262
    - PANDEY; MANN, NATURE, (2000), vol. 405, pages 837 - 846
    - PERSSON ET AL., J MOL. BIOL., (2006), vol. 357, pages 607 - 20
    - RADBRUCH ET AL., NAT. REV. IMMUNOL., (2006), vol. 6, pages 741 - 750
    - REDDY ET AL., NAT. BIOTECHNOL., (2010), vol. 28, pages 965 - U920
    - SCHAFFITZEL ET AL., J. IMMUNOL. METH., (1999), vol. 231, pages 119 - 135
    - SCHEID ET AL., NATURE, (2009), vol. 458, pages 636 - 640
    - SHEVCHENKO ET AL., PROC. NATL. ACAD. SCI. USA, (1996), vol. 93, pages 14440 - 14445
    - SILVA ET AL., MOL. CELL PROTEOMICS, (2006), vol. 5, no. 4, pages 589 - 607
    - SILVA ET AL., MOL. CELL PROTEOMICS, (2006), vol. 5, pages 144 - 156
    - SMITH ET AL., NAT. PROTOC., (2009), vol. 4, pages 372 - 384
    - TATUSOVA ET AL., FEMS MICROBIOL LETT., (1999), vol. 174, no. 2, pages 247 - 50
    - TRAGGIAI ET AL., NAT. MED., (2004), vol. 10, pages 871 - 875
    - VOGEL; MARCOTTE, NATURE PROTOCOLS, (2008), vol. 3, pages 1444 - 1451
    - WASHBURN ET AL., NAT. BIOTECHNOL., (2001), vol. 19, pages 242 - 247
    - WEINSTEIN ET AL., SCIENCE, (2009), vol. 324, pages 807 - 810
    - WRAMMERT ET AL., NATURE, (2008), vol. 453, pages 667 - 671
    - ZAHND ET AL., NAT. METHODS, (2007), vol. 4, pages 269 - 279
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