EP2791683 - BIOMARKERS AND PARAMETERS FOR PREECLAMPSIA [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 21.09.2018 Database last updated on 28.05.2024 | |
Former | The patent has been granted Status updated on 13.10.2017 | ||
Former | Grant of patent is intended Status updated on 15.06.2017 | ||
Former | Examination is in progress Status updated on 22.11.2016 | Most recent event Tooltip | 17.07.2020 | Lapse of the patent in a contracting state New state(s): AL, IS | published on 19.08.2020 [2020/34] | Applicant(s) | For all designated states Mycartis N.V. Technologiepark 4 9052 Gent / BE | [2017/46] |
Former [2014/44] | For all designated states Mycartis N.V. Technologiepark 4 9052 Gent / BE | ||
Former [2014/43] | For all designated states Pronota NV Technologiepark 4 9052 Zwijnaarde / BE | Inventor(s) | 01 /
THOMAS, Gregoire Van Duysestraat 42 B-9160 Lokeren / BE | 02 /
TUYTTEN, Robin Snugboro Glanmire Village, Glanmire, Co. Cork / IE | 03 /
MOERMAN, Piet Pontstraat 87 B-9831 Deurle / BE | [2014/43] | Representative(s) | Denjean, Eric Cabinet Laurent et Charras Le Contemporain 50, chemin de la Bruyère 69574 Dardilly / FR | [2017/46] |
Former [2014/43] | Boxall, Sarah Jane Boxall IPM Ltd 9 King Street Sandwich Kent CT13 9BT / GB | Application number, filing date | 12812560.6 | 14.12.2012 | [2017/46] | WO2012EP75643 | Priority number, date | EP20110193847 | 15.12.2011 Original published format: EP 11193847 | US201161576273P | 15.12.2011 Original published format: US 201161576273 P | EP20120168955 | 22.05.2012 Original published format: EP 12168955 | US201261650145P | 22.05.2012 Original published format: US 201261650145 P | [2014/43] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO2013087887 | Date: | 20.06.2013 | Language: | EN | [2013/25] | Type: | A2 Application without search report | No.: | EP2791683 | Date: | 22.10.2014 | Language: | EN | The application published by WIPO in one of the EPO official languages on 20.06.2013 takes the place of the publication of the European patent application. | [2014/43] | Type: | B1 Patent specification | No.: | EP2791683 | Date: | 15.11.2017 | Language: | EN | [2017/46] | Search report(s) | International search report - published on: | EP | 24.10.2013 | Classification | IPC: | G01N33/68 | [2014/43] | CPC: |
G01N33/689 (EP,CN,US);
G01N33/68 (RU);
G01N2800/368 (EP,CN,US);
G01N2800/60 (EP,CN,US)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2014/43] | Extension states | BA | Not yet paid | ME | Not yet paid | Title | German: | BIOMARKER UND PARAMETER FÜR PRÄEKLAMPSIE | [2014/43] | English: | BIOMARKERS AND PARAMETERS FOR PREECLAMPSIA | [2014/43] | French: | BIOMARQUEURS ET PARAMÈTRES POUR PRÉ-ÉCLAMPSIE | [2014/43] | Entry into regional phase | 02.07.2014 | National basic fee paid | 02.07.2014 | Designation fee(s) paid | 02.07.2014 | Examination fee paid | Examination procedure | 02.07.2014 | Examination requested [2014/43] | 25.02.2015 | Amendment by applicant (claims and/or description) | 18.08.2015 | Despatch of a communication from the examining division (Time limit: M04) | 27.01.2016 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time | 04.04.2016 | Reply to a communication from the examining division | 04.05.2016 | Despatch of a communication from the examining division (Time limit: M06) | 14.11.2016 | Reply to a communication from the examining division | 12.06.2017 | Communication of intention to grant the patent | 03.10.2017 | Fee for grant paid | 03.10.2017 | Fee for publishing/printing paid | 03.10.2017 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 18.08.2015 | Opposition(s) | 17.08.2018 | No opposition filed within time limit [2018/43] | Request for further processing for: | The application is deemed to be withdrawn due to failure to reply to the examination report | 04.04.2016 | Request for further processing filed | 04.04.2016 | Full payment received (date of receipt of payment) Request granted | 21.04.2016 | Decision despatched | Fees paid | Renewal fee | 22.12.2014 | Renewal fee patent year 03 | 04.04.2016 | Renewal fee patent year 04 | 30.11.2016 | Renewal fee patent year 05 | Penalty fee | Additional fee for renewal fee | 31.12.2015 | 04   M06   Fee paid on   04.04.2016 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 14.12.2012 | AL | 15.11.2017 | AT | 15.11.2017 | CY | 15.11.2017 | CZ | 15.11.2017 | DK | 15.11.2017 | EE | 15.11.2017 | ES | 15.11.2017 | FI | 15.11.2017 | HR | 15.11.2017 | IT | 15.11.2017 | LT | 15.11.2017 | LV | 15.11.2017 | MC | 15.11.2017 | MK | 15.11.2017 | NL | 15.11.2017 | PL | 15.11.2017 | PT | 15.11.2017 | RO | 15.11.2017 | RS | 15.11.2017 | SE | 15.11.2017 | SI | 15.11.2017 | SK | 15.11.2017 | SM | 15.11.2017 | TR | 15.11.2017 | IE | 14.12.2017 | LU | 14.12.2017 | MT | 14.12.2017 | BG | 15.02.2018 | NO | 15.02.2018 | GR | 16.02.2018 | IS | 15.03.2018 | [2020/33] |
Former [2020/28] | HU | 14.12.2012 | |
AT | 15.11.2017 | ||
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CZ | 15.11.2017 | ||
DK | 15.11.2017 | ||
EE | 15.11.2017 | ||
ES | 15.11.2017 | ||
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PT | 15.11.2017 | ||
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TR | 15.11.2017 | ||
IE | 14.12.2017 | ||
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MT | 14.12.2017 | ||
BG | 15.02.2018 | ||
NO | 15.02.2018 | ||
GR | 16.02.2018 | ||
Former [2020/16] | HU | 14.12.2012 | |
AT | 15.11.2017 | ||
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CZ | 15.11.2017 | ||
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ES | 15.11.2017 | ||
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SM | 15.11.2017 | ||
TR | 15.11.2017 | ||
IE | 14.12.2017 | ||
LU | 14.12.2017 | ||
MT | 14.12.2017 | ||
BG | 15.02.2018 | ||
NO | 15.02.2018 | ||
GR | 16.02.2018 | ||
Former [2019/51] | HU | 14.12.2012 | |
AT | 15.11.2017 | ||
CY | 15.11.2017 | ||
CZ | 15.11.2017 | ||
DK | 15.11.2017 | ||
EE | 15.11.2017 | ||
ES | 15.11.2017 | ||
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MK | 15.11.2017 | ||
NL | 15.11.2017 | ||
PL | 15.11.2017 | ||
RO | 15.11.2017 | ||
RS | 15.11.2017 | ||
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SM | 15.11.2017 | ||
IE | 14.12.2017 | ||
LU | 14.12.2017 | ||
MT | 14.12.2017 | ||
BG | 15.02.2018 | ||
NO | 15.02.2018 | ||
GR | 16.02.2018 | ||
Former [2019/31] | HU | 14.12.2012 | |
AT | 15.11.2017 | ||
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CZ | 15.11.2017 | ||
DK | 15.11.2017 | ||
EE | 15.11.2017 | ||
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SK | 15.11.2017 | ||
SM | 15.11.2017 | ||
IE | 14.12.2017 | ||
LU | 14.12.2017 | ||
MT | 14.12.2017 | ||
BG | 15.02.2018 | ||
NO | 15.02.2018 | ||
GR | 16.02.2018 | ||
Former [2019/30] | AT | 15.11.2017 | |
CY | 15.11.2017 | ||
CZ | 15.11.2017 | ||
DK | 15.11.2017 | ||
EE | 15.11.2017 | ||
ES | 15.11.2017 | ||
FI | 15.11.2017 | ||
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MC | 15.11.2017 | ||
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PL | 15.11.2017 | ||
RO | 15.11.2017 | ||
RS | 15.11.2017 | ||
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SI | 15.11.2017 | ||
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SM | 15.11.2017 | ||
IE | 14.12.2017 | ||
LU | 14.12.2017 | ||
MT | 14.12.2017 | ||
BG | 15.02.2018 | ||
NO | 15.02.2018 | ||
GR | 16.02.2018 | ||
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CY | 15.11.2017 | ||
CZ | 15.11.2017 | ||
DK | 15.11.2017 | ||
EE | 15.11.2017 | ||
ES | 15.11.2017 | ||
FI | 15.11.2017 | ||
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LT | 15.11.2017 | ||
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NL | 15.11.2017 | ||
PL | 15.11.2017 | ||
RO | 15.11.2017 | ||
RS | 15.11.2017 | ||
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SI | 15.11.2017 | ||
SK | 15.11.2017 | ||
SM | 15.11.2017 | ||
IE | 14.12.2017 | ||
LU | 14.12.2017 | ||
MT | 14.12.2017 | ||
BG | 15.02.2018 | ||
NO | 15.02.2018 | ||
GR | 16.02.2018 | ||
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CZ | 15.11.2017 | ||
DK | 15.11.2017 | ||
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ES | 15.11.2017 | ||
FI | 15.11.2017 | ||
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LT | 15.11.2017 | ||
LV | 15.11.2017 | ||
NL | 15.11.2017 | ||
PL | 15.11.2017 | ||
RO | 15.11.2017 | ||
RS | 15.11.2017 | ||
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SK | 15.11.2017 | ||
SM | 15.11.2017 | ||
IE | 14.12.2017 | ||
LU | 14.12.2017 | ||
MT | 14.12.2017 | ||
BG | 15.02.2018 | ||
NO | 15.02.2018 | ||
GR | 16.02.2018 | ||
Former [2018/43] | AT | 15.11.2017 | |
CY | 15.11.2017 | ||
CZ | 15.11.2017 | ||
DK | 15.11.2017 | ||
EE | 15.11.2017 | ||
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HR | 15.11.2017 | ||
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LT | 15.11.2017 | ||
LV | 15.11.2017 | ||
NL | 15.11.2017 | ||
PL | 15.11.2017 | ||
RO | 15.11.2017 | ||
RS | 15.11.2017 | ||
SE | 15.11.2017 | ||
SK | 15.11.2017 | ||
SM | 15.11.2017 | ||
LU | 14.12.2017 | ||
MT | 14.12.2017 | ||
BG | 15.02.2018 | ||
NO | 15.02.2018 | ||
GR | 16.02.2018 | ||
Former [2018/40] | AT | 15.11.2017 | |
CY | 15.11.2017 | ||
CZ | 15.11.2017 | ||
DK | 15.11.2017 | ||
EE | 15.11.2017 | ||
ES | 15.11.2017 | ||
FI | 15.11.2017 | ||
HR | 15.11.2017 | ||
IT | 15.11.2017 | ||
LT | 15.11.2017 | ||
LV | 15.11.2017 | ||
NL | 15.11.2017 | ||
PL | 15.11.2017 | ||
RO | 15.11.2017 | ||
RS | 15.11.2017 | ||
SE | 15.11.2017 | ||
SK | 15.11.2017 | ||
SM | 15.11.2017 | ||
BG | 15.02.2018 | ||
NO | 15.02.2018 | ||
GR | 16.02.2018 | ||
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CY | 15.11.2017 | ||
CZ | 15.11.2017 | ||
DK | 15.11.2017 | ||
EE | 15.11.2017 | ||
ES | 15.11.2017 | ||
FI | 15.11.2017 | ||
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IT | 15.11.2017 | ||
LT | 15.11.2017 | ||
LV | 15.11.2017 | ||
NL | 15.11.2017 | ||
PL | 15.11.2017 | ||
RS | 15.11.2017 | ||
SE | 15.11.2017 | ||
SK | 15.11.2017 | ||
SM | 15.11.2017 | ||
BG | 15.02.2018 | ||
NO | 15.02.2018 | ||
GR | 16.02.2018 | ||
Former [2018/37] | AT | 15.11.2017 | |
CY | 15.11.2017 | ||
CZ | 15.11.2017 | ||
DK | 15.11.2017 | ||
EE | 15.11.2017 | ||
ES | 15.11.2017 | ||
FI | 15.11.2017 | ||
HR | 15.11.2017 | ||
LT | 15.11.2017 | ||
LV | 15.11.2017 | ||
NL | 15.11.2017 | ||
PL | 15.11.2017 | ||
RS | 15.11.2017 | ||
SE | 15.11.2017 | ||
SK | 15.11.2017 | ||
SM | 15.11.2017 | ||
BG | 15.02.2018 | ||
NO | 15.02.2018 | ||
GR | 16.02.2018 | ||
Former [2018/35] | AT | 15.11.2017 | |
CY | 15.11.2017 | ||
CZ | 15.11.2017 | ||
DK | 15.11.2017 | ||
EE | 15.11.2017 | ||
ES | 15.11.2017 | ||
FI | 15.11.2017 | ||
HR | 15.11.2017 | ||
LT | 15.11.2017 | ||
LV | 15.11.2017 | ||
NL | 15.11.2017 | ||
RS | 15.11.2017 | ||
SE | 15.11.2017 | ||
SK | 15.11.2017 | ||
BG | 15.02.2018 | ||
NO | 15.02.2018 | ||
GR | 16.02.2018 | ||
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NL | 15.11.2017 | ||
RS | 15.11.2017 | ||
SE | 15.11.2017 | ||
BG | 15.02.2018 | ||
NO | 15.02.2018 | ||
GR | 16.02.2018 | ||
Former [2018/23] | AT | 15.11.2017 | |
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FI | 15.11.2017 | ||
HR | 15.11.2017 | ||
LT | 15.11.2017 | ||
NL | 15.11.2017 | ||
RS | 15.11.2017 | ||
SE | 15.11.2017 | ||
NO | 15.02.2018 | ||
GR | 16.02.2018 | ||
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LT | 15.11.2017 | ||
NL | 15.11.2017 | ||
NO | 15.02.2018 | Cited in | International search | [XD]WO2011128357 (PRONOTA NV [BE], et al) [XD] 1,18,20-23 * claims; Figure 1 *; | [Y]KR20100088217 (UNIV KONKUK IND COOP CORP [KR]) [Y] 1,18,20-23 * abstract *; | [XY]WO2004008946 (BETH ISRAEL HOSPITAL [US], et al) [X] 23 * claims 34-38; abstract * [Y] 1,18,20-22; | [XDY]WO2009094665 (PERKINELMER HEALTH SCI INC [US], et al) [XD] 23 * claims ; abstract; page 19, last paragraph-page 20, paragraph 4 * [Y] 1,18,20-22; | [XY]WO2010059952 (PERKINELMER HEALTH SCI INC [US], et al) [X] 23 * claims, abstract * [Y] 1,18,20-22; | [Y] - JISOOK PARK ET AL, "Discovery of the serum biomarker proteins in severe preeclampsia by proteomic analysis", EXPERIMENTAL AND MOLECULAR MEDICINE, (20110101), vol. 43, no. 7, doi:10.3858/emm.2011.43.7.047, ISSN 1226-3613, page 427, XP055019907 [Y] 1,18,20-23 * abstract; figures 3; discussion * DOI: http://dx.doi.org/10.3858/emm.2011.43.7.047 | [Y] - ROHRA, "Biochemical screening for the prediction of preeclampsia", JOURNAL OF THE PAKISTAN MEDICAL ASSOCIATION, (20050101), vol. 55, no. 2, ISSN 0030-9982, page 79, XP055045761 [Y] 1,18,20-23 * the whole document * | [A] - KAAJA R, "Predictors and risk factors of pre-eclampsia", MINERVA GINECOLOGICA, TORINO, IT, (20081001), vol. 60, no. 5, ISSN 0026-4784, pages 421 - 429, XP009156780 [A] 1,18,20-23 * abstract; table 2; paragraph "biochemical predictors of pre-eclampsia" * | [A] - LEWITT ET AL, "Regulation of insulin-like growth factor-binding protein-3 ternary complex formation in pregnancy", JOURNAL OF ENDOCRINOLOGY, (19981101), vol. 159, no. 2, doi:10.1677/joe.0.1590265, ISSN 0022-0795, pages 265 - 274, XP055001958 [A] 1,18,20-23 * the whole document * DOI: http://dx.doi.org/10.1677/joe.0.1590265 | by applicant | WO2009094665 | WO2011128357 | WO2009097584 | WO2009108073 | US2006105415 | US4816567 | US5270163 | US5578577 | US5141850 | US4775636 | US4853335 | US4859612 | US5079172 | US5202267 | US5514602 | US5616467 | US5681775 | US6107045 | US6974706 | US5108889 | US6027944 | US6482156 | US6511814 | US5824268 | US5726010 | US6001658 | US2008090305 | US2003109067 | - SOLOMON; SEELY, ENDOCRINOL METAB CLIN NORTH AM, (2006), vol. 35, no. 1, pages 157 - 71,VII | - SIBAI; BARTON, AM J OBSTET GYNECOL, (2007), vol. 196, no. 6 | - ROBERTS ET AL., HYPERTENSION, (2003), vol. 41, no. 3, pages 37 - 45 | - CONDE-AGUDELO ET AL., OBSTET GYNECOL, (2004), vol. 104, pages 1367 - 91 | - LEWITT ET AL., JOURNAL OF ENDOCRINOLOGY, (1998), vol. 159, page 265 | - MISTRY ET AL., HYPERTENSION, (2008), vol. 52, page 881 | - RAYMAN ET AL., AM J OBSTET GYNECOL, (2003), vol. 189, page 1343 | - BUJOLD ET AL., OBSTET GYNECOL, (2010), vol. 116, pages 402 - 14 | - MAYNARD ET AL., J CLIN INVEST, (2003), vol. 111, no. 5, pages 649 - 58 | - POLLIOTTI ET AL., OBSTET GYNECOL, (2003), vol. 101, pages 1266 - 74 | - ALBERTI ET AL., DIABETIC MEDICINE, (2006), vol. 23, pages 469 - 480 | - LANCET, vol. 366, pages 1059 - 1062 | - CRUZ ET AL., "Applications of Machine Learning in Cancer Prediction and Prognosis", CANCER INFORMATICS, (2007), vol. 2, pages 59 - 77 | - LOWRY ET AL., J BIOL CHEM, (1951), vol. 193, page 265 | - HARTREE, ANAL BIOCHEM, (1972), vol. 48, pages 422 - 427 | - KOHLER ET AL., NATURE, (1975), vol. 256, page 495 | - CLACKSON ET AL., NATURE, (1991), vol. 352, pages 624 - 628 | - MARKS ET AL., J MOL BIOL, (1991), vol. 222, pages 581 - 597 | - "Antibody Engineering: Methods and Protocols", LO,, Methods in Molecular Biology, HUMANA PRESS, (2004), vol. 248 | - ELLINGTON; SZOSTAK, NATURE, (1990), vol. 346, pages 818 - 822 | - TUERK; GOLD, SCIENCE, (1990), vol. 249, pages 505 - 510 | - HORWELL, TRENDS BIOTECHNOL, (1995), vol. 13, pages 132 - 134 | - G. FRENS, 1973 NATURE PHYSICAL SCIENCE, (1973), vol. 241, page 20 | - NIELSEN; GEIERSTANGER, J IMMUNOL METHODS, (2004), vol. 290, pages 107 - 20 | - LING ET AL., EXPERT REV MOL DIAGN, (2007), vol. 7, pages 87 - 98 | - "Mass Spectrometry of Proteins and Peptides", CHAPMAN,, Methods in Molecular Biology, HUMANA PRESS, (2000), vol. 146 | - BIEMANN, METHODS ENZYMOL, (1990), vol. 193, pages 455 - 79 | - "Biological Mass Spectrometry", BURLINGAME,, Methods in Enzymology, ACADEMIC PRESS, (2005), vol. 402 | - KUHN ET AL., PROTEOMICS, (2004), vol. 4, pages 1175 - 86 | - ZHONG ET AL., PRENATAL DIAGNOSIS, (2010), vol. 30, pages 293 - 308 | - ROYSTON ET AL., "Prognosis and prognostic research: Developing a prognostic model", BMJ 2009, (2009), vol. 338, page B604 | - TIBSHIRANI, "Regression shrinkage and selection via the lasso", J. ROYAL. STATIST. SOC B., (1996), vol. 58, no. 1, pages 267 - 288 | - BMJ, (2011), vol. 342, page D1875 |