EP2744487 - NO- AND H2S- RELEASING COMPOUNDS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 11.08.2017 Database last updated on 24.08.2024 | Most recent event Tooltip | 17.07.2020 | Lapse of the patent in a contracting state New state(s): AL | published on 19.08.2020 [2020/34] | Applicant(s) | For all designated states Research Foundation of the City University of New York 230 West 41st Street New York, NY 10036 / US | [N/P] |
Former [2014/26] | For all designated states Research Foundation Of The City University Of New York 230 West 41st Street New York, NY 10036 / US | Inventor(s) | 01 /
KASHFI, Khosrow City University of New York Medical School Department of Physiology Pharmacology and Neuroscience Harris Hall, Suite 301, 138th Street&Convent Ave New York, NY 10031 / US | 02 /
KODELA, Ravinder City University of New York Medical School Department of Physiology Pharmacology and Neuroscience Harris Hall, Suite 301, 138th Street&Convent Ave New York, NY 10031 / US | [2014/26] | Representative(s) | V.O. P.O. Box 87930 2508 DH Den Haag / NL | [2016/40] |
Former [2014/26] | Jansen, Cornelis Marinus V.O. Johan de Wittlaan 7 2517 JR Den Haag / NL | Application number, filing date | 12824542.0 | 15.08.2012 | [2016/40] | WO2012US50922 | Priority number, date | US201161523513P | 15.08.2011 Original published format: US 201161523513 P | US201261615700P | 26.03.2012 Original published format: US 201261615700 P | US201261635624P | 19.04.2012 Original published format: US 201261635624 P | [2014/26] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO2013025790 | Date: | 21.02.2013 | Language: | EN | [2013/08] | Type: | A2 Application without search report | No.: | EP2744487 | Date: | 25.06.2014 | Language: | EN | The application published by WIPO in one of the EPO official languages on 21.02.2013 takes the place of the publication of the European patent application. | [2014/26] | Type: | B1 Patent specification | No.: | EP2744487 | Date: | 05.10.2016 | Language: | EN | [2016/40] | Search report(s) | International search report - published on: | US | 10.05.2013 | (Supplementary) European search report - dispatched on: | EP | 27.01.2015 | Classification | IPC: | A61K31/385, C07D339/04, A61P29/00 | [2015/09] | CPC: |
A61K31/655 (EP,US);
C07C203/04 (US);
A61P29/00 (EP);
C07C327/48 (US);
C07C331/28 (US);
C07D271/08 (US);
C07D339/04 (EP,US);
C07D413/12 (US);
C07F9/65583 (US);
C07F9/6578 (US)
(-)
|
Former IPC [2014/26] | A61K31/13, A01N33/24 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2014/26] | Extension states | BA | Not yet paid | ME | Not yet paid | Title | German: | NO- UND H2S-FREISETZENDE VERBINDUNGEN | [2014/26] | English: | NO- AND H2S- RELEASING COMPOUNDS | [2014/26] | French: | COMPOSÉS LIBÉRANT NO ET H2S | [2014/26] | Entry into regional phase | 13.08.2013 | National basic fee paid | 13.08.2013 | Search fee paid | 13.08.2013 | Designation fee(s) paid | 13.08.2013 | Examination fee paid | Examination procedure | 13.08.2013 | Examination requested [2014/26] | 13.07.2015 | Amendment by applicant (claims and/or description) | 14.09.2015 | Despatch of a communication from the examining division (Time limit: M06) | 19.02.2016 | Reply to a communication from the examining division | 30.03.2016 | Despatch of a communication from the examining division (Time limit: M04) | 04.05.2016 | Reply to a communication from the examining division | 29.06.2016 | Communication of intention to grant the patent | 06.07.2016 | Fee for grant paid | 06.07.2016 | Fee for publishing/printing paid | 06.07.2016 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 14.09.2015 | Opposition(s) | 06.07.2017 | No opposition filed within time limit [2017/37] | Fees paid | Renewal fee | 31.07.2014 | Renewal fee patent year 03 | 27.08.2015 | Renewal fee patent year 04 | 29.08.2016 | Renewal fee patent year 05 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 15.08.2012 | AL | 05.10.2016 | AT | 05.10.2016 | BE | 05.10.2016 | CY | 05.10.2016 | CZ | 05.10.2016 | DK | 05.10.2016 | EE | 05.10.2016 | ES | 05.10.2016 | FI | 05.10.2016 | HR | 05.10.2016 | IT | 05.10.2016 | LT | 05.10.2016 | LV | 05.10.2016 | MC | 05.10.2016 | MK | 05.10.2016 | NL | 05.10.2016 | PL | 05.10.2016 | RO | 05.10.2016 | RS | 05.10.2016 | SE | 05.10.2016 | SI | 05.10.2016 | SK | 05.10.2016 | SM | 05.10.2016 | TR | 05.10.2016 | BG | 05.01.2017 | NO | 05.01.2017 | GR | 06.01.2017 | IS | 05.02.2017 | PT | 06.02.2017 | [2020/34] |
Former [2020/15] | HU | 15.08.2012 | |
AT | 05.10.2016 | ||
BE | 05.10.2016 | ||
CY | 05.10.2016 | ||
CZ | 05.10.2016 | ||
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EE | 05.10.2016 | ||
ES | 05.10.2016 | ||
FI | 05.10.2016 | ||
HR | 05.10.2016 | ||
IT | 05.10.2016 | ||
LT | 05.10.2016 | ||
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MK | 05.10.2016 | ||
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PL | 05.10.2016 | ||
RO | 05.10.2016 | ||
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SE | 05.10.2016 | ||
SI | 05.10.2016 | ||
SK | 05.10.2016 | ||
SM | 05.10.2016 | ||
TR | 05.10.2016 | ||
BG | 05.01.2017 | ||
NO | 05.01.2017 | ||
GR | 06.01.2017 | ||
IS | 05.02.2017 | ||
PT | 06.02.2017 | ||
Former [2019/51] | HU | 15.08.2012 | |
AT | 05.10.2016 | ||
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MK | 05.10.2016 | ||
NL | 05.10.2016 | ||
PL | 05.10.2016 | ||
RO | 05.10.2016 | ||
RS | 05.10.2016 | ||
SE | 05.10.2016 | ||
SI | 05.10.2016 | ||
SK | 05.10.2016 | ||
SM | 05.10.2016 | ||
BG | 05.01.2017 | ||
NO | 05.01.2017 | ||
GR | 06.01.2017 | ||
IS | 05.02.2017 | ||
PT | 06.02.2017 | ||
Former [2019/46] | HU | 15.08.2012 | |
AT | 05.10.2016 | ||
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CY | 05.10.2016 | ||
CZ | 05.10.2016 | ||
DK | 05.10.2016 | ||
EE | 05.10.2016 | ||
ES | 05.10.2016 | ||
FI | 05.10.2016 | ||
HR | 05.10.2016 | ||
IT | 05.10.2016 | ||
LT | 05.10.2016 | ||
LV | 05.10.2016 | ||
MC | 05.10.2016 | ||
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PL | 05.10.2016 | ||
RO | 05.10.2016 | ||
RS | 05.10.2016 | ||
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SI | 05.10.2016 | ||
SK | 05.10.2016 | ||
SM | 05.10.2016 | ||
BG | 05.01.2017 | ||
NO | 05.01.2017 | ||
GR | 06.01.2017 | ||
IS | 05.02.2017 | ||
PT | 06.02.2017 | ||
Former [2019/31] | HU | 15.08.2012 | |
AT | 05.10.2016 | ||
BE | 05.10.2016 | ||
CZ | 05.10.2016 | ||
DK | 05.10.2016 | ||
EE | 05.10.2016 | ||
ES | 05.10.2016 | ||
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IT | 05.10.2016 | ||
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MC | 05.10.2016 | ||
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PL | 05.10.2016 | ||
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SK | 05.10.2016 | ||
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BG | 05.01.2017 | ||
NO | 05.01.2017 | ||
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IS | 05.02.2017 | ||
PT | 06.02.2017 | ||
Former [2018/18] | AT | 05.10.2016 | |
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LT | 05.10.2016 | ||
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MC | 05.10.2016 | ||
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PL | 05.10.2016 | ||
RO | 05.10.2016 | ||
RS | 05.10.2016 | ||
SE | 05.10.2016 | ||
SI | 05.10.2016 | ||
SK | 05.10.2016 | ||
SM | 05.10.2016 | ||
BG | 05.01.2017 | ||
NO | 05.01.2017 | ||
GR | 06.01.2017 | ||
IS | 05.02.2017 | ||
PT | 06.02.2017 | ||
Former [2017/52] | AT | 05.10.2016 | |
BE | 05.10.2016 | ||
CZ | 05.10.2016 | ||
DK | 05.10.2016 | ||
EE | 05.10.2016 | ||
ES | 05.10.2016 | ||
FI | 05.10.2016 | ||
HR | 05.10.2016 | ||
IT | 05.10.2016 | ||
LT | 05.10.2016 | ||
LV | 05.10.2016 | ||
NL | 05.10.2016 | ||
PL | 05.10.2016 | ||
RO | 05.10.2016 | ||
RS | 05.10.2016 | ||
SE | 05.10.2016 | ||
SI | 05.10.2016 | ||
SK | 05.10.2016 | ||
SM | 05.10.2016 | ||
BG | 05.01.2017 | ||
NO | 05.01.2017 | ||
GR | 06.01.2017 | ||
IS | 05.02.2017 | ||
PT | 06.02.2017 | ||
Former [2017/38] | AT | 05.10.2016 | |
BE | 05.10.2016 | ||
CZ | 05.10.2016 | ||
DK | 05.10.2016 | ||
EE | 05.10.2016 | ||
ES | 05.10.2016 | ||
FI | 05.10.2016 | ||
HR | 05.10.2016 | ||
IT | 05.10.2016 | ||
LT | 05.10.2016 | ||
LV | 05.10.2016 | ||
NL | 05.10.2016 | ||
PL | 05.10.2016 | ||
RO | 05.10.2016 | ||
RS | 05.10.2016 | ||
SE | 05.10.2016 | ||
SK | 05.10.2016 | ||
SM | 05.10.2016 | ||
BG | 05.01.2017 | ||
NO | 05.01.2017 | ||
GR | 06.01.2017 | ||
IS | 05.02.2017 | ||
PT | 06.02.2017 | ||
Former [2017/37] | AT | 05.10.2016 | |
BE | 05.10.2016 | ||
CZ | 05.10.2016 | ||
DK | 05.10.2016 | ||
EE | 05.10.2016 | ||
ES | 05.10.2016 | ||
FI | 05.10.2016 | ||
HR | 05.10.2016 | ||
IT | 05.10.2016 | ||
LT | 05.10.2016 | ||
LV | 05.10.2016 | ||
NL | 05.10.2016 | ||
PL | 05.10.2016 | ||
RO | 05.10.2016 | ||
RS | 05.10.2016 | ||
SE | 05.10.2016 | ||
SK | 05.10.2016 | ||
SM | 05.10.2016 | ||
NO | 05.01.2017 | ||
GR | 06.01.2017 | ||
IS | 05.02.2017 | ||
PT | 06.02.2017 | ||
Former [2017/36] | AT | 05.10.2016 | |
BE | 05.10.2016 | ||
CZ | 05.10.2016 | ||
DK | 05.10.2016 | ||
EE | 05.10.2016 | ||
ES | 05.10.2016 | ||
FI | 05.10.2016 | ||
HR | 05.10.2016 | ||
LT | 05.10.2016 | ||
LV | 05.10.2016 | ||
NL | 05.10.2016 | ||
PL | 05.10.2016 | ||
RO | 05.10.2016 | ||
RS | 05.10.2016 | ||
SE | 05.10.2016 | ||
SK | 05.10.2016 | ||
NO | 05.01.2017 | ||
GR | 06.01.2017 | ||
IS | 05.02.2017 | ||
PT | 06.02.2017 | ||
Former [2017/34] | AT | 05.10.2016 | |
BE | 05.10.2016 | ||
CZ | 05.10.2016 | ||
DK | 05.10.2016 | ||
ES | 05.10.2016 | ||
FI | 05.10.2016 | ||
HR | 05.10.2016 | ||
LT | 05.10.2016 | ||
LV | 05.10.2016 | ||
NL | 05.10.2016 | ||
PL | 05.10.2016 | ||
RS | 05.10.2016 | ||
SE | 05.10.2016 | ||
NO | 05.01.2017 | ||
GR | 06.01.2017 | ||
IS | 05.02.2017 | ||
PT | 06.02.2017 | ||
Former [2017/33] | AT | 05.10.2016 | |
BE | 05.10.2016 | ||
DK | 05.10.2016 | ||
ES | 05.10.2016 | ||
FI | 05.10.2016 | ||
HR | 05.10.2016 | ||
LT | 05.10.2016 | ||
LV | 05.10.2016 | ||
NL | 05.10.2016 | ||
PL | 05.10.2016 | ||
RS | 05.10.2016 | ||
SE | 05.10.2016 | ||
NO | 05.01.2017 | ||
GR | 06.01.2017 | ||
IS | 05.02.2017 | ||
PT | 06.02.2017 | ||
Former [2017/26] | AT | 05.10.2016 | |
BE | 05.10.2016 | ||
ES | 05.10.2016 | ||
FI | 05.10.2016 | ||
HR | 05.10.2016 | ||
LT | 05.10.2016 | ||
LV | 05.10.2016 | ||
NL | 05.10.2016 | ||
PL | 05.10.2016 | ||
RS | 05.10.2016 | ||
SE | 05.10.2016 | ||
NO | 05.01.2017 | ||
GR | 06.01.2017 | ||
IS | 05.02.2017 | ||
PT | 06.02.2017 | ||
Former [2017/12] | LV | 05.10.2016 | Documents cited: | Search | [I]WO2006111791 (CTG PHARMA S R L [IT], et al) [I] 1-20* page 6, line 5 - line 13; claims 1,4,5 * | International search | [X]US2007275905 (WALLACE JOHN L [CA], et al); | [Y]US2008293781 (GASCO ALBERTO [IT], et al); | [Y]US2010210607 (WALLACE JOHN [CA], et al); | [XP] - CHATTOPADHYAY ET AL., "NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide- releasing hybrid is a potent inhibitor of colon cancer cell growth in vitro and in a xenograft mouse model.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, (2012), vol. 419, pages 523 - 528, XP055136912 DOI: http://dx.doi.org/10.1016/j.bbrc.2012.02.051 | [A] - LAZZARATO ET AL., "New Nitric Oxide or Hydrogen Sulfide Releasing Aspirins.", J. MED. CHEM., 2011, (20110621), vol. 54, pages 5478 - 5484, XP055016631 DOI: http://dx.doi.org/10.1021/jm2004514 | by applicant | WO2006111791 | US2007275905 | - "Anti-Inflammatory Agents as Cancer Therapeutics", K. KASHFI, Contemporary Aspects of Biomedical Research: Drug Discovery, Advances in Pharmacol, ELSEVIER, INC., (2009), vol. 57, pages 31 - 89 | - J. PHARM. SCI., (1977), vol. 66, page 2 | - WINTER ET AL., PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE, (1962), vol. 111, pages 544 - 547 | - KODELA ET AL., ACS MED. CHEM. LETT., (2012), vol. 3, no. 3, pages 257 - 262 | - PENNING ET AL., J. MED. CHEM., (1997), vol. 40, pages 1347 - 1365 | - CHATTOPADHYAY ET AL., BIOCHEMICAL PHARMACOLOGY, (2012), vol. 83, no. 6, pages 715 - 722 | - KASHFI ET AL., J. PHARMACOL. EXP. THER., (2005), vol. 312, pages 978 - 988 | - BHATIA ET AL., FASEB. J., (2005), vol. 19, pages 1196 - 1198 | - HUANG ET AL., J. MOL. BIOL., (2010), vol. 396, pages 708 - 718 | - OLSON, BIOCHIM. BIOPHYS. ACTA, (2009), vol. 1787, pages 856 - 863 | - KULMACZ ET AL., PROSTAGLANDINS, (1983), vol. 25, pages 531 - 540 | - CHATTOPADHYAY ET AL., BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, (2012), vol. 419, no. 3, pages 523 - 528 | - DELEON ET AL., ANAL. BIOCHEM., (2012), vol. 421, pages 203 - 207 | - MEADE ET AL., J. BIOL. CHEM., (1993), vol. 268, pages 6610 - 6614 | - RIENDEAU ET AL., CAN. J. PHYSIOL. PHARMACOL., (1997), vol. 75, pages 1088 - 1095 | - BEST R ET AL., BR J PHARMACOL, (1984), vol. 82, pages 107 - 116 | - CHATTOPADHYAY M ET AL., J PHARMACOL EXP THER., (2010), vol. 335, pages 443 - 50 | - LI L ET AL., FREE RADIO BIOL MED, (2007), vol. 42, pages 706 - 19 | - HUANG S ET AL., JMOL BIOL, (2010), vol. 396, pages 708 - 18 | - LEE ZW ET AL., PLOS ONE, (2011), vol. 6, no. 6, page E21077 | - PINTO L ET AL., PHARM PHARMACOL COMMUNICATION, (1988), vol. 4, pages 502 - 505 | - KULMACZ RJ ET AL., PROSTAGLANDINS, (1983), vol. 25, pages 531 - 540 |