EP2753605 - COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 07.02.2020 Database last updated on 14.06.2024 | |
Former | The patent has been granted Status updated on 22.02.2019 | ||
Former | Grant of patent is intended Status updated on 04.10.2018 | ||
Former | Examination is in progress Status updated on 17.11.2017 | Most recent event Tooltip | 01.07.2022 | Lapse of the patent in a contracting state New state(s): MK | published on 03.08.2022 [2022/31] | Applicant(s) | For all designated states Lantheus Medical Imaging, Inc. 331 Treble Cove Road North Billerica, MA 01862 / US | [2014/29] | Inventor(s) | 01 /
RADEKE, Heike, S. 15 Seaver Farm Lane South Grafton, MA 01560 / US | 02 /
CESATI, Richard, R. 63 Nashua Road Pepperell, MA 01463 / US | 03 /
PUROHIT, Ajay 33 Country Village Lane Sudbury, MA 01776-1638 / US | 04 /
HARRIS, Thomas, D. 56 Zion Hill Road Salem, NH 03079 / US | 05 /
ROBINSON, Simon, P. 22 Kettell Plain Road Stow, MA 01775 / US | 06 /
YU, Ming 360 Littleton Road Chelmsford, MA 01824 / US | 07 /
CASEBIER, David, S. 161 Ember Lane Carlisle, MA 01741 / US | 08 /
HU, Carol, Hui 209 Riverwoods Drive New Hope, PA 18938 / US | 09 /
BROEKEMA, Matthias 209 Riverwoods Drive New Hope, PA 18938 / US | 10 /
ONTHANK, David, C. 21 Kirk Farm Road Groton, MA 01450 / US | [2014/29] | Representative(s) | Carpmaels & Ransford LLP One Southampton Row London WC1B 5HA / GB | [2014/29] | Application number, filing date | 12829763.7 | 07.09.2012 | [2019/13] | WO2012US54309 | Priority number, date | US201161533133P | 09.09.2011 Original published format: US 201161533133 P | US201261656492P | 06.06.2012 Original published format: US 201261656492 P | US201261656489P | 06.06.2012 Original published format: US 201261656489 P | [2014/29] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO2013036869 | Date: | 14.03.2013 | Language: | EN | [2013/11] | Type: | A2 Application without search report | No.: | EP2753605 | Date: | 16.07.2014 | Language: | EN | The application published by WIPO in one of the EPO official languages on 14.03.2013 takes the place of the publication of the European patent application. | [2014/29] | Type: | B1 Patent specification | No.: | EP2753605 | Date: | 27.03.2019 | Language: | EN | [2019/13] | Search report(s) | International search report - published on: | KR | 02.05.2013 | (Supplementary) European search report - dispatched on: | EP | 22.06.2015 | Classification | IPC: | C07D233/44, A61K49/00, A61K49/06, C07C257/14, A61K51/04, C07C279/04, C07C279/06, C07C279/08, C07C279/12, C07C279/14, C07C281/18, C07D233/46, C07C217/70, C07D209/14 | [2015/30] | CPC: |
A61P9/06 (EP);
C07D233/46 (EP,CN,KR,US);
C07C257/14 (EP,CN,US);
A61K51/0459 (US);
A61K51/04 (US);
A61K51/0453 (KR,US);
A61K51/0497 (US);
C07B59/001 (KR);
C07B59/002 (KR);
C07C217/70 (EP,CN,US);
C07C279/04 (EP,CN,US);
C07C279/06 (EP,CN,KR,US);
C07C279/08 (EP,CN,US);
C07C279/10 (KR);
C07C279/12 (EP,CN,US);
C07C279/14 (EP,CN,US);
C07C281/18 (EP,CN,US);
C07C291/00 (CN);
C07D209/08 (CN);
C07D209/14 (EP,CN,KR,US);
C07D233/48 (CN);
C07D233/88 (CN);
C07D235/30 (CN);
C07D239/42 (CN);
C07D249/04 (CN);
C07D249/14 (CN);
C07D263/56 (CN);
C07D265/30 (CN);
C07D277/42 (CN);
C07D295/073 (CN);
C07D295/096 (CN);
C07D295/215 (CN);
A61K51/041 (US);
|
Former IPC [2014/29] | C07D233/44, A61K49/00, A61K49/06 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2014/29] | Extension states | BA | Not yet paid | ME | Not yet paid | Title | German: | ZUSAMMENSETZUNGEN, VERFAHREN UND SYSTEME ZUR SYNTHESE UND VERWENDUNG VON KONTRASTMITTELN | [2014/29] | English: | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | [2014/29] | French: | COMPOSITIONS, PROCÉDÉS ET SYSTÈMES DE SYNTHÈSE ET D'UTILISATION D'AGENTS D'IMAGERIE | [2014/29] | Entry into regional phase | 08.04.2014 | National basic fee paid | 08.04.2014 | Search fee paid | 08.04.2014 | Designation fee(s) paid | 08.04.2014 | Examination fee paid | Examination procedure | 08.04.2014 | Examination requested [2014/29] | 19.01.2016 | Amendment by applicant (claims and/or description) | 15.11.2017 | Despatch of a communication from the examining division (Time limit: M06) | 21.05.2018 | Reply to a communication from the examining division | 05.10.2018 | Communication of intention to grant the patent | 15.02.2019 | Fee for grant paid | 15.02.2019 | Fee for publishing/printing paid | 15.02.2019 | Receipt of the translation of the claim(s) | Divisional application(s) | EP19165299.9 / EP3567029 | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 15.11.2017 | Opposition(s) | 03.01.2020 | No opposition filed within time limit [2020/11] | Fees paid | Renewal fee | 29.09.2014 | Renewal fee patent year 03 | 28.09.2015 | Renewal fee patent year 04 | 27.09.2016 | Renewal fee patent year 05 | 27.09.2017 | Renewal fee patent year 06 | 27.09.2018 | Renewal fee patent year 07 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 07.09.2012 | AL | 27.03.2019 | AT | 27.03.2019 | CY | 27.03.2019 | CZ | 27.03.2019 | EE | 27.03.2019 | HR | 27.03.2019 | LT | 27.03.2019 | LV | 27.03.2019 | MC | 27.03.2019 | MK | 27.03.2019 | MT | 27.03.2019 | PL | 27.03.2019 | RO | 27.03.2019 | RS | 27.03.2019 | SI | 27.03.2019 | SK | 27.03.2019 | SM | 27.03.2019 | TR | 27.03.2019 | BG | 27.06.2019 | GR | 28.06.2019 | IS | 27.07.2019 | PT | 27.07.2019 | IE | 07.09.2019 | LU | 07.09.2019 | BE | 30.09.2019 | CH | 30.09.2019 | LI | 30.09.2019 | [2022/31] |
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CH | 30.09.2019 | ||
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Former [2019/33] | LT | 27.03.2019 | Documents cited: | Search | [Y]WO2008083056 (BRISTOL MYERS SQUIBB PHARMA CO [US], et al) [Y] 1-14 * page 1, paragraphs 1, 2 * * page 2, paragraph 6 * * page 6, paragraph 15 * * page 10, paragraph 25 * * page 16, paragraph 44 * * page 21, paragraphs 51, 52 ** page 73; claims 20-25 *; | [Y]WO2011097649 (LANTHEUS MEDICAL IMAGING INC [US], et al) [Y] 1-14 * page 32 - page 38 * * page 71, paragraphs 1st, 3rd * | International search | [A]WO0009115 (SMITHKLINE BEECHAM CORP [US], et al); | [X]US2006127309 (RAFFEL DAVID M [US], et al); | [X]WO2008083056 (BRISTOL MYERS SQUIBB PHARMA CO [US], et al); | [XP]WO2011143360 (LANTHEUS MEDICAL IMAGING INC [US], et al); | [A] - RAFFEL, D.V. ET AL., "Radiolabeled phenethylguanidines: Novel Imaging Agents for cardiac Sympathetic Neurons and Adrenergic Tumors.", J. MED. CHEM., (2007), vol. 50, no. 9, pages 2078 - 2088, XP002506339 DOI: http://dx.doi.org/10.1021/JM061398Y | by applicant | US4270537 | US4596556 | US4790824 | US4886499 | US4940460 | US4941880 | US5015235 | US5064413 | US5141496 | US5190521 | US5312335 | US5328483 | US5334144 | US5339163 | US5383851 | US5417662 | US5466220 | US5480381 | US5503627 | US5520639 | US5527288 | US5569189 | US5599302 | WO9713537 | US5649912 | WO9737705 | US5704911 | US5893397 | WO9934850 | US5993412 | US6511648 | WO2005079391 | WO2005105159 | WO2008083056 | WO2011005322 | WO2011097649 | - BELETSKAYA et al., Synthesis, (20070000), pages 2534 - 2538 | - HUBBARD et al., J. Org. Chem., (20080000), vol. 73, pages 316 - 319 | - FILIMONOV et al., Org. Lett., (20080000), vol. 10, pages 3961 - 3964 | - KRASNOKUTSKAYA et al., Synthesis, (20070000), pages 81 - 84 | - A. KLAPARS; S. L. BUCHWALD, J. Am. Chem. Soc., (20020000), vol. 124, pages 14844 - 14845 | - THIEBES et al., Syntett, (19980000), pages 141 - 142 | - MURPHY et al., J. Am. Chem. Soc., (20070000), vol. 129, pages 15434 - 15435 | - THOMPSON et al., Synthesis, (20050000), pages 547 - 550 | - G. W. KABALKA; A. R. MEREDDY, Organometallics, (20040000), vol. 23, pages 4519 - 4521 | - KRASZKIEWICZ et al., Synthesis, (20060000), pages 1195 - 1199 | - GANGULY et al., Synthesis, (20100000), pages 1467 - 1472 | - ISKRA et al., Synthesis, (20040000), pages 1869 - 1873 | - CASTANET, Tetrahedron Lett., (20020000), vol. 43, pages 5047 - 5048 | - PRAKASH, J. Am. Chem. Soc., (20040000), vol. 126, pages 15570 - 15776 | - LULINSKI et al., Synthesis, (20040000), pages 441 - 445 | - GANGULY, Synthesis, (20050000), pages 1103 - 1108 | - RAJESH et al., Org. Chem., (20070000), vol. 72, pages 5867 - 5869 | - BENGEL FM; SCHWAIGER M, "Assessment of cardiac sympathetic neuronal function using PET imaging", J Nucl Cardiol, (20040000), vol. 11, no. 5, doi:doi:10.1016/j.nuclcard.2004.06.133, pages 603 - 16, XP004592870 DOI: http://dx.doi.org/10.1016/j.nuclcard.2004.06.133 | - HENNEMAN MM; BENGEL FM; VAN DER WALL EE; KNUUTI J; BAX JJ, "Cardiac neuronal imaging: application in the evaluation of cardiac disease", J Nucl Cardiol., (20080000), vol. 15, no. 3, doi:doi:10.1016/j.nuclcard.2008.02.023, pages 442 - 55, XP022676108 DOI: http://dx.doi.org/10.1016/j.nuclcard.2008.02.023 | - TRAVIN MI, "Cardiac neuronal imaging at the edge of clinical application", Cardiol Clin., (20090000), vol. 27, no. 2, pages 311 - 27 | - CARRIO I., "Cardiac neurotransmission imaging", JNucl Med., (20010000), vol. 42, no. 7, pages 1062 - 76, XP002597251 | - "Periodic Table of the Elements, CAS version", Handbook of Chemistry and Physics, 75th ed, . | - BERGE et al., "describe pharmaceutically acceptable salts in detail", J. Pharmaceutical Sciences, (19770000), vol. 66, pages 1 - 19 | - Wilen S.H. et al, Tetrahedron, vol. 33, page 2725 | - WILEN, S.H., Tables of Resolving Agents and Optical Resolutions, Univ. of Notre Dame Press, (19720000), page 268 | WO2011US24109 |