EP2763674 - SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF CANCERS, INCLUDING HEPATOCELLULAR CARCINOMA, AND AS INHIBITORS OF HEPATITIS VIRUS REPLICATION [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 13.01.2017 Database last updated on 19.10.2024 | Most recent event Tooltip | 13.01.2017 | Application deemed to be withdrawn | published on 15.02.2017 [2017/07] | Applicant(s) | For all designated states Baruch S. Blumberg Institute The Pennsylvania Biotechnology Center 3805 Old Easton Road Doylestown PA 18902 / US | For all designated states Drexel University 3141 Chestnut Street Philadelphia Pennsylvania 19104 / US | [2015/23] |
Former [2014/33] | For all designated states Institute for Hepatitis and Virus Research The Pennsylvania Biotechnology Center 3805 Old Easton Road Doylestown, PA 18902 / US | Inventor(s) | 01 /
CUCONATI, Andrea 204 Weldy Avenue Oreland, PA 19075 / US | 02 /
XU, Xiaodong 4564 Summer Hill Drive Doylestown, PA 18902 / US | 03 /
BLOCK, Timothy, M. 80 Foxcroft Drive Doylestown, PA 18901 / US | [2014/33] | Representative(s) | Kelly, Donal Morgan FRKelly 27 Clyde Road Dublin D04 F838 / IE | [N/P] |
Former [2014/33] | Kelly, Donal Morgan FRKelly 27 Clyde Road Dublin 4 / IE | Application number, filing date | 12838333.8 | 04.10.2012 | WO2012US58674 | Priority number, date | US201161542907P | 04.10.2011 Original published format: US 201161542907 P | [2014/33] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2013052613 | Date: | 11.04.2013 | Language: | EN | [2013/15] | Type: | A1 Application with search report | No.: | EP2763674 | Date: | 13.08.2014 | Language: | EN | The application published by WIPO in one of the EPO official languages on 11.04.2013 takes the place of the publication of the European patent application. | [2014/33] | Search report(s) | International search report - published on: | US | 11.04.2013 | (Supplementary) European search report - dispatched on: | EP | 26.03.2015 | Classification | IPC: | A61K31/425, A61K31/426, C07D417/04, C07D417/12, A61K31/427, A61P35/00, A61P31/12, C07D277/42, C07D417/14, C07D487/04, C07D495/04 | [2015/17] | CPC: |
C07D417/14 (EP,US);
A61K31/425 (EP,US);
A61K31/426 (EP,US);
A61P1/16 (EP);
A61P31/12 (EP);
A61P31/14 (EP);
A61P31/20 (EP);
A61P35/00 (EP);
A61P35/02 (EP);
A61P35/04 (EP);
A61P43/00 (EP);
C07D277/42 (EP,US);
C07D417/04 (EP,US);
C07D417/12 (EP,US);
C07D487/04 (EP,US);
|
Former IPC [2015/15] | A61K31/425, A61K31/426, C07D417/00, C07D417/02, A61K31/427, A61P35/00, A61P31/12 | ||
Former IPC [2014/33] | A61K31/425, A61K31/426, C07D417/00, C07D417/02 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2014/33] | Title | German: | SUBSTITUIERTE AMINOTHIAZOLE ALS HEMMER VON KREBSZELLEN EINSCHLIESSLICH HEPATOZELLULÄRER KARZINOME UND ALS HEPATITIS-VIRUS-REPLIKATIONSHEMMER | [2014/33] | English: | SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF CANCERS, INCLUDING HEPATOCELLULAR CARCINOMA, AND AS INHIBITORS OF HEPATITIS VIRUS REPLICATION | [2014/33] | French: | AMINOTHIAZOLES SUBSTITUÉS EN TANT QU'INHIBITEURS DE CANCERS, NOTAMMENT LE CARCINOME HÉPATOCELLULAIRE, ET EN TANT QU'INHIBITEURS DE LA RÉPLICATION DU VIRUS DE L'HÉPATITE | [2014/33] | Entry into regional phase | 06.05.2014 | National basic fee paid | 06.05.2014 | Search fee paid | 06.05.2014 | Designation fee(s) paid | 06.05.2014 | Examination fee paid | Examination procedure | 06.05.2014 | Examination requested [2014/33] | 12.10.2015 | Amendment by applicant (claims and/or description) | 01.03.2016 | Despatch of a communication from the examining division (Time limit: M06) | 13.09.2016 | Application deemed to be withdrawn, date of legal effect [2017/07] | 11.10.2016 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2017/07] | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 01.03.2016 | Fees paid | Renewal fee | 25.09.2014 | Renewal fee patent year 03 | 12.10.2015 | Renewal fee patent year 04 | Penalty fee | Additional fee for renewal fee | 31.10.2016 | 05   M06   Not yet paid |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [XY]WO03015773 (JANSSEN PHARMACEUTICA NV [BE], et al) [X] 1-5,9-13 * page 25, lines 24, 34-37 - page 26, lines 1-3; examples 38, 39, 54 * [Y] 1-13; | [XY]WO2005099673 (ICAGEN INC [US], et al) [X] 1-5,9-13 * page 3, line 14; page 6, line 8; page 27, line 10; claim 20;; compounds 9.2t, 9.2w, 9.2x, 9.2y, 9.2aa, 11.2a * [Y] 1-13; | [XY]WO2007103550 (ACHILLION PHARMACEUTICALS INC [US], et al) [X] 1-5,9-13 * paragraphs [0153] , [0188]; claim - * [Y] 1-13; | [XY]WO2008083098 (UNIV JOHNS HOPKINS [US], et al) [X] 1-5,9-13 * paragraphs [0011] , [0017] , [0082] , [0083]; compounds (I), (II) * [Y] 1-13; | [XY]WO2009114552 (UNIV LELAND STANFORD JUNIOR [US], et al) [X] 1-5,9-13 * paragraphs [0202] - [0205]; table 1; compounds 3,13,73 * [Y] 1-13; | [XY]WO2010111711 (ZACHARON PHARMACEUTICALS INC [US], et al) [X] 1-5,9-13 * paragraphs [00188] , [00189]; figure 36A * [Y] 1-13; | [XY] - HAY, MICHAEL P. ET AL, "4-Pyridylanilinothiazoles That Selectively Target von Hippel-Lindau Deficient Renal Cell Carcinoma Cells by Inducing Autophagic Cell Death", JOURNAL OF MEDICINAL CHEMISTRY, (2010), vol. 53, no. 2, doi:10.1021/JM901457W, pages 787 - 797, XP002736467 [X] 1-5,9-13 * compounds 1, 9, 56, 80 * [Y] 1-13 DOI: http://dx.doi.org/10.1021/JM901457W 10.1021/JM901457W | [AP] - DIGHE, SATISH N. ET AL, "A remarkably high-speed solution-phase combinatorial synthesis of 2-substituted-amino-4-aryl thiazoles in polar solvents in the absence of a catalyst under ambient conditions and study of their antimicrobial activities", ISRN ORGANIC CHEMISTRY 434613, 6 PP. CODEN: IOCSBF; ISSN: 2090-5157 URL: HTTP://DOWNLOADS.HINDAWI.COM/ISRN/OC/2011/434613.PDF, (2011), vol. 2011, no. 434613, doi:10.5402/2011/434613, XP002736468 [AP] 1-13 * compound thiazole 3b (disclaimed);; table 3 * DOI: http://dx.doi.org/10.5402/2011/434613 10.5402/2011/434613 | International search | [X]US2005227989 (WANG XIAODONG [US], et al); | [A]US2007203147 (COBURN CRAIG A [US], et al); | [X]US2007213301 (ZHANG SOUMING [US], et al) |