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Extract from the Register of European Patents

EP About this file: EP2771012

EP2771012 - NEW COMPOUNDS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  10.06.2016
Database last updated on 06.07.2024
Most recent event   Tooltip10.06.2016Application deemed to be withdrawnpublished on 13.07.2016  [2016/28]
Applicant(s)For all designated states
GlaxoSmithKline Intellectual Property (No. 2) Limited
980 Great West Road
Brentford, Middlesex TW8 9GS / GB
[2016/21]
Former [2014/36]For all designated states
Glaxosmithkline Intellectual Property (No. 2) Limited
980 Great West Road
Brentford, Middlesex TW8 9GS / GB
Inventor(s)01 / HENDRICKSON, Thomas, Francis
5852 Crest Drive
Encinitas, CA 92024 / US
02 / HO, Koc-Kan
2836 Valley View Avenue
Holladay, UT 84417 / US
03 / SAUNDERS, Michael, David
10864 Berrywood Court
Sandy, UT 84070 / US
04 / STEVENS, Brian, John
1766 East Princeton Avenue
Salt Lake City, UT 84108 / US
05 / SWIERCZEK, Krzysztof
7843 Tiger Court
West Jordan, UT 84081 / US
06 / WRIGHT, Kevin, Bret
9018 Kings Hill Place
Cottonwood Heights, UT 84121 / US
 [2014/36]
Representative(s)Reed, Michael Antony
GlaxoSmithKline
Global Patents (CN925.1)
980 Great West Road
Brentford, Middlesex TW8 9GS / GB
[2014/36]
Application number, filing date12843835.523.10.2012
WO2012US61439
Priority number, dateUS201161550679P24.10.2011         Original published format: US 201161550679 P
[2014/36]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2013062943
Date:02.05.2013
Language:EN
[2013/18]
Type: A1 Application with search report 
No.:EP2771012
Date:03.09.2014
Language:EN
The application published by WIPO in one of the EPO official languages on 02.05.2013 takes the place of the publication of the European patent application.
[2014/36]
Search report(s)International search report - published on:US02.05.2013
(Supplementary) European search report - dispatched on:EP28.05.2015
ClassificationIPC:A61K31/52, C07D473/34, C07H19/16, A61P35/00
[2015/26]
CPC:
C07D473/34 (EP,US); C07H19/16 (US); A61K31/7052 (EP,US);
A61K31/706 (EP,US); A61K31/7064 (EP,US); A61K31/7076 (EP,US);
A61P35/00 (EP) (-)
Former IPC [2014/36]A61K31/52
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2014/36]
Extension statesBA22.04.2014
ME22.04.2014
TitleGerman:NEUE VERBINDUNGEN[2014/36]
English:NEW COMPOUNDS[2014/36]
French:NOUVEAUX COMPOSÉS[2014/36]
Entry into regional phase22.04.2014National basic fee paid 
22.04.2014Search fee paid 
22.04.2014Designation fee(s) paid 
22.04.2014Examination fee paid 
Examination procedure22.04.2014Amendment by applicant (claims and/or description)
22.04.2014Examination requested  [2014/36]
05.01.2016Application deemed to be withdrawn, date of legal effect  [2016/28]
02.02.2016Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2016/28]
Fees paidRenewal fee
07.10.2014Renewal fee patent year 03
07.10.2015Renewal fee patent year 04
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[X]WO0140799  (CV THERAPEUTICS INC [US], et al) [X] 1-4,7,8,10,14 * pages 8f; formula 1; compounds (27) and (28) in example 4 on pages 54f *;
 [X]WO03074083  (PFIZER [US], et al) [X] 1-3,6-8,10,13-15 * the whole document, in particular the claims; examples 2(B)6, 2(B)14, 2(F)3, 2(F)16, 2(F)19, 2(G)9, 2(G)61, 2(G)69 *;
 [X]WO2004016635  (CV THERAPEUTICS INC [US]) [X] 1,2,6-8,10,13,14 * in particular claims 1 and 20; example 9; page 55 *;
 [X]WO2007067559  (UNIV MINNESOTA [US], et al) [X] 1-3,7,10,13,14 * claims; compounds 139 and 146 in examples 15 and 16 and in schemes 16 and 17 *;
 [X]  - KUNG P P ET AL, "Design, synthesis, and biological evaluation of novel human 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP) substrates", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, AMSTERDAM, NL, vol. 15, no. 11, ISSN 0960-894X, (20050602), pages 2829 - 2833, (20050602), XP027801098 [X] 1-4,6,10,14,15 * the whole document, in particular second paragraph in right-hand column on page 2832; compounds 17 and 24 in table 2 *
 [X]  - MALIK A ET AL., "Coumaroyl Adenosine and Lignan Glycoside from Amaranthus spinosus L.", POLISH JOURNAL OF CHEMISTRY, (2006), vol. 80, pages 259 - 263, XP002739312 [X] 1-3,7,10,13,14 * compound 2 on pages 260-263; page 259 first paragraph; page 263 "extraction and isolation" *
 [X]  - MORIS F ET AL, "A USEFUL AND VERSATILE PROCEDURE FOR THE ACYLATION OF NUCLEOSIDES THROUGH AN ENZYMIC REACTION", THE JOURNAL OF ORGANIC CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, (19930101), vol. 58, no. 3, doi:10.1021/JO00055A018, ISSN 0022-3263, pages 653 - 660, XP009054627 [X] 1-3,7,9,10 * schemes I and II; entry 8 in table III, entry 3h in table IV and entries 7g and 7h in table VII as well as on pages 658-660 *

DOI:   http://dx.doi.org/10.1021/jo00055a018
 [X]  - ANDREW MARSH ET AL, "Atom Transfer Polymerization: Use of Uridine and Adenosine Derivatized Monomers and Initiators", MACROMOLECULES, (19991201), vol. 32, no. 26, doi:10.1021/ma991438q, ISSN 0024-9297, pages 8725 - 8731, XP055187711 [X] 1-3,7,10 * compound 5 in figures 1,2 and on page 8726 *

DOI:   http://dx.doi.org/10.1021/ma991438q
 [X]  - AFZAL KHAN ET AL, "Hydrogen Bond Template-Directed Polymerization of Protected 5'-Acryloylnucleosides", MACROMOLECULES, (19991001), vol. 32, no. 20, doi:10.1021/ma990283j, ISSN 0024-9297, pages 6560 - 6564, XP055187885 [X] 1-3,7,9,10 * scheme 1 with B=adenine; page 6561, left-hand column, third paragraph; second pararaph on the right-hand column of the same page *

DOI:   http://dx.doi.org/10.1021/ma990283j
 [X]  - TAKAMURA T ET AL, "Synthesis and antitumor activities of N6,N6-dimethyladenosine carboxylate analogues", CHEMICAL AND PHARMACEUTICAL BULLETIN, PHARMACEUTICAL SOCIETY OF JAPAN, JP, (19890101), vol. 37, no. 10, ISSN 0009-2363, pages 2828 - 2831, XP002181857 [X] 1,2,10,14,15 * compound 3q in chart 1, table I and right-hand column on page 2830; table II a) *
 [X]  - REGISTRY, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, (20020905), Database accession no. 446850631, XP002739313 [X] 1-3,7,9,10 * compound with registry number 446850-63-1 *
International search[Y]US2008132525  (WAHHAB AMAL [CA], et al);
 [Y]  - SIEDLECKI ET AL., "Establishment and functional validation of a structural homology model for human DNA methyltransferase 1", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, (20030627), vol. 306, no. 2, pages 558 - 563, XP055066318

DOI:   http://dx.doi.org/10.1016/S0006-291X(03)01000-3
 [A]  - COHEN ET AL., "Determinants of cofactor binding to DNA methyltransferases: insights from a systematic series of structural variants of S-adenosylhomocysteine", ORG.BIOMOL.CHEM., (2005), vol. 3, no. 1, pages 152 - 161, XP002412376

DOI:   http://dx.doi.org/10.1039/b415446k
 [A]  - YANG ET AL., "Structure of the bacteriophage T4DNA adenine methyltransferase", NATURE STRUCTURAL BIOLOGY, (200310), vol. 10, no. 10, pages 849 - 855, XP008119541

DOI:   http://dx.doi.org/10.1038/nsb973
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