EP2788354 - FUNCTIONALISATION OF CAGE AMINE LIGANDS FOR METALLO-RADIOPHARMACEUTICALS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 06.10.2017 Database last updated on 24.08.2024 | Most recent event Tooltip | 17.07.2020 | Lapse of the patent in a contracting state New state(s): AL | published on 19.08.2020 [2020/34] | Applicant(s) | For all designated states The University of Melbourne 205-211 Grattan Street Carlton, Victoria 3053 / AU | [2016/48] |
Former [2014/42] | For all designated states The University Of Melbourne 205-211 Grattan Street Carlton, Victoria 3053 / AU | Inventor(s) | 01 /
DONNELLY, Paul c/- UoM Commercial Ltd The University of Melbourne Victoria 3010 / AU | 02 /
PATERSON, Brett C/- UoM Commercial Ltd The University of Melbourne Victoria 3010 / AU | [2014/42] | Representative(s) | Regimbeau 20, rue de Chazelles 75847 Paris Cedex 17 / FR | [2014/42] | Application number, filing date | 12856248.5 | 06.12.2012 | [2016/48] | WO2012AU01483 | Priority number, date | US201161567255P | 06.12.2011 Original published format: US 201161567255 P | [2014/42] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2013082655 | Date: | 13.06.2013 | Language: | EN | [2013/24] | Type: | A1 Application with search report | No.: | EP2788354 | Date: | 15.10.2014 | Language: | EN | The application published by WIPO in one of the EPO official languages on 13.06.2013 takes the place of the publication of the European patent application. | [2014/42] | Type: | B1 Patent specification | No.: | EP2788354 | Date: | 30.11.2016 | Language: | EN | [2016/48] | Search report(s) | International search report - published on: | AU | 13.06.2013 | (Supplementary) European search report - dispatched on: | EP | 15.05.2015 | Classification | IPC: | C07D487/08, A61K51/06, A61K51/08 | [2014/42] | CPC: |
A61K51/0482 (EP,US);
A61K47/547 (EP,US);
A61K51/082 (EP,US);
A61K51/088 (EP,US);
C07D487/08 (EP,US)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2014/42] | Extension states | BA | Not yet paid | ME | Not yet paid | Title | German: | FUNKTIONALISIERUNG VON CAGE-AMINLIGANDEN FÜR METALLO-RADIOPHARMAZEUTIKA | [2014/42] | English: | FUNCTIONALISATION OF CAGE AMINE LIGANDS FOR METALLO-RADIOPHARMACEUTICALS | [2014/42] | French: | FONCTIONNALISATION DE LIGANDS AMINE À EFFET DE CAGE POUR PRODUITS MÉTALLO-RADIOPHARMACEUTIQUES | [2014/42] | Entry into regional phase | 03.07.2014 | National basic fee paid | 03.07.2014 | Search fee paid | 03.07.2014 | Designation fee(s) paid | 03.07.2014 | Examination fee paid | Examination procedure | 03.07.2014 | Examination requested [2014/42] | 08.12.2015 | Amendment by applicant (claims and/or description) | 20.06.2016 | Communication of intention to grant the patent | 18.10.2016 | Fee for grant paid | 18.10.2016 | Fee for publishing/printing paid | 18.10.2016 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 20.06.2016 | Opposition(s) | 31.08.2017 | No opposition filed within time limit [2017/45] | Fees paid | Renewal fee | 11.12.2014 | Renewal fee patent year 03 | 10.12.2015 | Renewal fee patent year 04 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 06.12.2012 | AL | 30.11.2016 | CY | 30.11.2016 | CZ | 30.11.2016 | EE | 30.11.2016 | HR | 30.11.2016 | IS | 30.11.2016 | LT | 30.11.2016 | LV | 30.11.2016 | MC | 30.11.2016 | MK | 30.11.2016 | PL | 30.11.2016 | RO | 30.11.2016 | RS | 30.11.2016 | SI | 30.11.2016 | SK | 30.11.2016 | SM | 30.11.2016 | TR | 30.11.2016 | LU | 06.12.2016 | MT | 06.12.2016 | BG | 28.02.2017 | GR | 01.03.2017 | [2020/34] |
Former [2018/45] | HU | 06.12.2012 | |
CY | 30.11.2016 | ||
CZ | 30.11.2016 | ||
EE | 30.11.2016 | ||
HR | 30.11.2016 | ||
IS | 30.11.2016 | ||
LT | 30.11.2016 | ||
LV | 30.11.2016 | ||
MC | 30.11.2016 | ||
MK | 30.11.2016 | ||
PL | 30.11.2016 | ||
RO | 30.11.2016 | ||
RS | 30.11.2016 | ||
SI | 30.11.2016 | ||
SK | 30.11.2016 | ||
SM | 30.11.2016 | ||
TR | 30.11.2016 | ||
LU | 06.12.2016 | ||
MT | 06.12.2016 | ||
BG | 28.02.2017 | ||
GR | 01.03.2017 | ||
Former [2018/43] | HU | 06.12.2012 | |
CY | 30.11.2016 | ||
CZ | 30.11.2016 | ||
EE | 30.11.2016 | ||
HR | 30.11.2016 | ||
IS | 30.11.2016 | ||
LT | 30.11.2016 | ||
LV | 30.11.2016 | ||
MC | 30.11.2016 | ||
MK | 30.11.2016 | ||
PL | 30.11.2016 | ||
RO | 30.11.2016 | ||
RS | 30.11.2016 | ||
SI | 30.11.2016 | ||
SK | 30.11.2016 | ||
SM | 30.11.2016 | ||
LU | 06.12.2016 | ||
MT | 06.12.2016 | ||
BG | 28.02.2017 | ||
GR | 01.03.2017 | ||
Former [2018/30] | HU | 06.12.2012 | |
CY | 30.11.2016 | ||
CZ | 30.11.2016 | ||
EE | 30.11.2016 | ||
HR | 30.11.2016 | ||
IS | 30.11.2016 | ||
LT | 30.11.2016 | ||
LV | 30.11.2016 | ||
MC | 30.11.2016 | ||
MK | 30.11.2016 | ||
PL | 30.11.2016 | ||
RO | 30.11.2016 | ||
RS | 30.11.2016 | ||
SI | 30.11.2016 | ||
SK | 30.11.2016 | ||
SM | 30.11.2016 | ||
LU | 06.12.2016 | ||
BG | 28.02.2017 | ||
GR | 01.03.2017 | ||
Former [2017/49] | CZ | 30.11.2016 | |
EE | 30.11.2016 | ||
HR | 30.11.2016 | ||
LT | 30.11.2016 | ||
LV | 30.11.2016 | ||
MC | 30.11.2016 | ||
PL | 30.11.2016 | ||
RO | 30.11.2016 | ||
RS | 30.11.2016 | ||
SI | 30.11.2016 | ||
SK | 30.11.2016 | ||
SM | 30.11.2016 | ||
LU | 06.12.2016 | ||
BG | 28.02.2017 | ||
GR | 01.03.2017 | ||
Former [2017/42] | CZ | 30.11.2016 | |
EE | 30.11.2016 | ||
HR | 30.11.2016 | ||
LT | 30.11.2016 | ||
LV | 30.11.2016 | ||
MC | 30.11.2016 | ||
PL | 30.11.2016 | ||
RO | 30.11.2016 | ||
RS | 30.11.2016 | ||
SK | 30.11.2016 | ||
SM | 30.11.2016 | ||
BG | 28.02.2017 | ||
GR | 01.03.2017 | ||
Former [2017/37] | CZ | 30.11.2016 | |
EE | 30.11.2016 | ||
HR | 30.11.2016 | ||
LT | 30.11.2016 | ||
LV | 30.11.2016 | ||
PL | 30.11.2016 | ||
RO | 30.11.2016 | ||
RS | 30.11.2016 | ||
SK | 30.11.2016 | ||
SM | 30.11.2016 | ||
GR | 01.03.2017 | ||
Former [2017/26] | HR | 30.11.2016 | |
LT | 30.11.2016 | ||
LV | 30.11.2016 | ||
PL | 30.11.2016 | ||
RS | 30.11.2016 | ||
GR | 01.03.2017 | ||
Former [2017/12] | LV | 30.11.2016 | Documents cited: | Search | [A]WO2010063069 (UNIV MELBOURNE [AU], et al) [A] 1-17 * the whole document *; | [A] - NADINE DI BARTOLO ET AL, "New 64Cu PET imaging agents for personalised medicine and drug development using the hexa-aza cage, SarAr", ORGANIC & BIOMOLECULAR CHEMISTRY, (20060101), vol. 4, no. 17, doi:10.1039/b605615f, ISSN 1477-0520, page 3350, XP055187005 [A] 1-17 * the whole document * DOI: http://dx.doi.org/10.1039/b605615f | [A] - Voss D.S. ET AL, "Positron emission tomography (PET) imaging of neuroblastoma and melanoma with Cu-SarAr immunoconjugates", Proceedings of the National Academy of Sciences of the United States of America, vol. 104, no. 44, (20070101), URL: http://www.pnas.org/content/104/44/17489.full.pdf, (20150430), XP055187006 [A] 1-17 * the whole document * | [AP] - MAGGIE S. COOPER ET AL, "Comparison of 64 Cu-Complexing Bifunctional Chelators for Radioimmunoconjugation: Labeling Efficiency, Specific Activity, and in Vitro / in Vivo Stability", BIOCONJUGATE CHEMISTRY, (20120516), vol. 23, no. 5, doi:10.1021/bc300037w, ISSN 1043-1802, pages 1029 - 1039, XP055187002 [AP] 1-17 * the whole document * DOI: http://dx.doi.org/10.1021/bc300037w | [A] - MICHELLE T. MA ET AL, "A new bifunctional chelator for copper radiopharmaceuticals: a cage amine ligand with a carboxylate functional group for conjugation to peptides", CHEMICAL COMMUNICATIONS, (20090101), no. 22, doi:10.1039/b903426a, ISSN 1359-7345, page 3237, XP055057963 [A] 1-17 * the whole document * DOI: http://dx.doi.org/10.1039/b903426a | International search | [X]WO2010063069 (UNIV MELBOURNE [AU], et al); | [X] - JARRETT, B. R. ET AL., "Synthesis of 64Cu-Labeled Magnetic Nanoparticles for Multimodal Imaging", BIOCONJUGATE CHEMISTRY, (2008), vol. 19, pages 1496 - 1504, XP002547464 DOI: http://dx.doi.org/10.1021/BC800108V | [X] - MA, M. T. ET AL., "A New Bifunctional Chelator for Copper Radiopharmaceuticals: A Cage Amine Ligand with a Carboxylate Functional Group for Conjugation to Peptides", CHEMICAL COMMUNICATIONS, (2009), vol. 22, pages 3237 - 3239, XP055057963 DOI: http://dx.doi.org/10.1039/b903426a | [X] - HUANG, CHIUN-WEI ET AL., "Biological Stability Evaluation of the alpha2beta1 Receptor Imaging Agents: Diamsar and DOTA Conjugated DGEA Peptide", BIOCONJUGATE CHEMISTRY, (2011), vol. 22, no. 2, pages 256 - 263, XP055071397 DOI: http://dx.doi.org/10.1021/bc100388g | [X] - WEI, LIHUI. ET AL., "64Cu-Labeled CB-TE2A and Diamsar-Conjugated RGD Peptide Analogs for Targeting Angiogenesis: Comparison of their Biological Activity", NUCLEAR MEDICINE AND BIOLOGY, (2009), vol. 36, no. 3, pages 277 - 285, XP026029883 DOI: http://dx.doi.org/10.1016/j.nucmedbio.2008.12.008 | [X] - MA, M. T. ET AL., "Macrobicyclic Cage Amine Ligands for Copper Radiopharmaceuticals: A Single Bivalent Cage Amine Containing Two Lys3-bombesin Targeting Peptides", INORGANIC CHEMISTRY, (2011), vol. 50, no. 14, pages 6701 - 6710, XP055071399 DOI: http://dx.doi.org/10.1021/ic200681s |