Extract from the Register of European Patents

EP About this file: EP2798058

EP2798058 - METHODS AND COMPOSITIONS FOR THE CLINICAL DERIVATION OF AN ALLOGENIC CELL AND THERAPEUTIC USES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  24.08.2018
Database last updated on 11.04.2026
FormerThe patent has been granted
Status updated on  15.09.2017
FormerGrant of patent is intended
Status updated on  24.04.2017
FormerExamination is in progress
Status updated on  07.11.2016
Most recent event   Tooltip17.07.2020Lapse of the patent in a contracting state
New state(s): AL
published on 19.08.2020  [2020/34]
Applicant(s)For all designated states
Patel, Amit
1040 Chartwell Court
Salt Lake City, Utah 84103 / US
[2014/45]
Inventor(s)01 / see applicant
...
 [2014/45]
Representative(s)Walker, Ross Thomson
Forresters IP LLP
Skygarden
Erika-Mann-Strasse 11
80636 München / DE
[2017/42]
Former [2014/45]Walker, Ross Thomson
Forresters
Skygarden
Erika-Mann-Strasse 11
80636 München / DE
Application number, filing date12862921.931.12.2012
[2017/42]
WO2012US72331
Priority number, dateUS201161582070P30.12.2011         Original published format: US 201161582070 P
US201261591211P26.01.2012         Original published format: US 201261591211 P
[2014/45]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2013102219
Date:04.07.2013
Language:EN
[2013/27]
Type: A1 Application with search report 
No.:EP2798058
Date:05.11.2014
Language:EN
The application published by WIPO in one of the EPO official languages on 04.07.2013 takes the place of the publication of the European patent application.
[2014/45]
Type: B1 Patent specification 
No.:EP2798058
Date:18.10.2017
Language:EN
[2017/42]
Search report(s)International search report - published on:KR04.07.2013
(Supplementary) European search report - dispatched on:EP22.04.2015
ClassificationIPC:C12N5/073, C12N5/0735, A61K35/12, A61K35/51
[2015/21]
CPC:
C12N5/0665 (EP); C12N5/0682 (US); A61K35/51 (EP,US);
A61P1/16 (EP); A61P11/00 (EP); A61P11/06 (EP);
A61P13/12 (EP); A61P15/10 (EP); A61P17/02 (EP);
A61P19/00 (EP); A61P19/02 (EP); A61P25/00 (EP);
A61P3/10 (EP); A61P37/02 (EP); A61P37/06 (EP);
A61P39/00 (EP); A61P9/00 (EP); A61P9/10 (EP);
C12N5/0605 (US); C12N5/0653 (US); C12N5/0654 (US);
C12N5/0655 (US); C12N5/0657 (US) (-)
Former IPC [2014/45]C12N5/073, C12N5/0735, A61K35/12
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2014/45]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:VERFAHREN UND ZUSAMMENSETZUNGEN FÜR DIE KLINISCHE ABLEITUNG EINER ALLOGENEN ZELLE UND THERAPEUTISCHE VERWENDUNGEN[2014/45]
English:METHODS AND COMPOSITIONS FOR THE CLINICAL DERIVATION OF AN ALLOGENIC CELL AND THERAPEUTIC USES[2014/45]
French:MÉTHODES ET COMPOSITIONS PERMETTANT L'OBTENTION, À DES FINS CLINIQUES, D'UNE CELLULE ALLOGÈNE ET SES UTILISATIONS THÉRAPEUTIQUES[2014/45]
Entry into regional phase03.07.2014National basic fee paid 
03.07.2014Search fee paid 
03.07.2014Designation fee(s) paid 
03.07.2014Examination fee paid 
Examination procedure03.07.2014Examination requested  [2014/45]
23.11.2015Amendment by applicant (claims and/or description)
18.02.2016Despatch of a communication from the examining division (Time limit: M06)
26.08.2016Reply to a communication from the examining division
27.10.2016Despatch of a communication from the examining division (Time limit: M04)
06.03.2017Reply to a communication from the examining division
25.04.2017Communication of intention to grant the patent
05.09.2017Fee for grant paid
05.09.2017Fee for publishing/printing paid
05.09.2017Receipt of the translation of the claim(s)
Divisional application(s)EP17191442.7  / EP3321355
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  18.02.2016
Opposition(s)19.07.2018No opposition filed within time limit [2018/39]
Fees paidRenewal fee
29.12.2014Renewal fee patent year 03
28.12.2015Renewal fee patent year 04
27.12.2016Renewal fee patent year 05
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Lapses during opposition  TooltipHU31.12.2012
AL18.10.2017
AT18.10.2017
CY18.10.2017
CZ18.10.2017
DK18.10.2017
EE18.10.2017
FI18.10.2017
HR18.10.2017
LT18.10.2017
LV18.10.2017
MC18.10.2017
MK18.10.2017
PL18.10.2017
PT18.10.2017
RO18.10.2017
RS18.10.2017
SI18.10.2017
SK18.10.2017
SM18.10.2017
TR18.10.2017
CH31.12.2017
IE31.12.2017
LI31.12.2017
LU31.12.2017
MT31.12.2017
BG18.01.2018
NO18.01.2018
GR19.01.2018
IS18.02.2018
[2020/34]
Former [2020/28]HU31.12.2012
AT18.10.2017
CY18.10.2017
CZ18.10.2017
DK18.10.2017
EE18.10.2017
FI18.10.2017
HR18.10.2017
LT18.10.2017
LV18.10.2017
MC18.10.2017
MK18.10.2017
PL18.10.2017
PT18.10.2017
RO18.10.2017
RS18.10.2017
SI18.10.2017
SK18.10.2017
SM18.10.2017
TR18.10.2017
CH31.12.2017
IE31.12.2017
LI31.12.2017
LU31.12.2017
MT31.12.2017
BG18.01.2018
NO18.01.2018
GR19.01.2018
IS18.02.2018
Former [2020/16]HU31.12.2012
AT18.10.2017
CY18.10.2017
CZ18.10.2017
DK18.10.2017
EE18.10.2017
FI18.10.2017
HR18.10.2017
LT18.10.2017
LV18.10.2017
MC18.10.2017
MK18.10.2017
PL18.10.2017
RO18.10.2017
RS18.10.2017
SI18.10.2017
SK18.10.2017
SM18.10.2017
TR18.10.2017
CH31.12.2017
IE31.12.2017
LI31.12.2017
LU31.12.2017
MT31.12.2017
BG18.01.2018
NO18.01.2018
GR19.01.2018
IS18.02.2018
Former [2019/51]HU31.12.2012
AT18.10.2017
CY18.10.2017
CZ18.10.2017
DK18.10.2017
EE18.10.2017
FI18.10.2017
HR18.10.2017
LT18.10.2017
LV18.10.2017
MC18.10.2017
MK18.10.2017
PL18.10.2017
RO18.10.2017
RS18.10.2017
SI18.10.2017
SK18.10.2017
SM18.10.2017
CH31.12.2017
IE31.12.2017
LI31.12.2017
LU31.12.2017
MT31.12.2017
BG18.01.2018
NO18.01.2018
GR19.01.2018
IS18.02.2018
Former [2019/47]HU31.12.2012
AT18.10.2017
CY18.10.2017
CZ18.10.2017
DK18.10.2017
EE18.10.2017
FI18.10.2017
HR18.10.2017
LT18.10.2017
LV18.10.2017
MC18.10.2017
PL18.10.2017
RO18.10.2017
RS18.10.2017
SI18.10.2017
SK18.10.2017
SM18.10.2017
CH31.12.2017
IE31.12.2017
LI31.12.2017
LU31.12.2017
MT31.12.2017
BG18.01.2018
NO18.01.2018
GR19.01.2018
IS18.02.2018
Former [2019/31]HU31.12.2012
AT18.10.2017
CZ18.10.2017
DK18.10.2017
EE18.10.2017
FI18.10.2017
HR18.10.2017
LT18.10.2017
LV18.10.2017
MC18.10.2017
PL18.10.2017
RO18.10.2017
RS18.10.2017
SI18.10.2017
SK18.10.2017
SM18.10.2017
CH31.12.2017
IE31.12.2017
LI31.12.2017
LU31.12.2017
MT31.12.2017
BG18.01.2018
NO18.01.2018
GR19.01.2018
IS18.02.2018
Former [2019/30]AT18.10.2017
CZ18.10.2017
DK18.10.2017
EE18.10.2017
FI18.10.2017
HR18.10.2017
LT18.10.2017
LV18.10.2017
MC18.10.2017
PL18.10.2017
RO18.10.2017
RS18.10.2017
SI18.10.2017
SK18.10.2017
SM18.10.2017
CH31.12.2017
IE31.12.2017
LI31.12.2017
LU31.12.2017
MT31.12.2017
BG18.01.2018
NO18.01.2018
GR19.01.2018
IS18.02.2018
Former [2018/52]AT18.10.2017
CZ18.10.2017
DK18.10.2017
EE18.10.2017
FI18.10.2017
HR18.10.2017
LT18.10.2017
LV18.10.2017
PL18.10.2017
RO18.10.2017
RS18.10.2017
SI18.10.2017
SK18.10.2017
SM18.10.2017
CH31.12.2017
IE31.12.2017
LI31.12.2017
LU31.12.2017
MT31.12.2017
BG18.01.2018
NO18.01.2018
GR19.01.2018
IS18.02.2018
Former [2018/45]AT18.10.2017
CZ18.10.2017
DK18.10.2017
EE18.10.2017
FI18.10.2017
HR18.10.2017
LT18.10.2017
LV18.10.2017
PL18.10.2017
RO18.10.2017
RS18.10.2017
SK18.10.2017
SM18.10.2017
IE31.12.2017
LU31.12.2017
MT31.12.2017
BG18.01.2018
NO18.01.2018
GR19.01.2018
IS18.02.2018
Former [2018/43]AT18.10.2017
CZ18.10.2017
DK18.10.2017
EE18.10.2017
FI18.10.2017
HR18.10.2017
LT18.10.2017
LV18.10.2017
PL18.10.2017
RO18.10.2017
RS18.10.2017
SK18.10.2017
SM18.10.2017
LU31.12.2017
MT31.12.2017
BG18.01.2018
NO18.01.2018
GR19.01.2018
IS18.02.2018
Former [2018/40]AT18.10.2017
CZ18.10.2017
DK18.10.2017
EE18.10.2017
FI18.10.2017
HR18.10.2017
LT18.10.2017
LV18.10.2017
PL18.10.2017
RO18.10.2017
RS18.10.2017
SK18.10.2017
SM18.10.2017
BG18.01.2018
NO18.01.2018
GR19.01.2018
IS18.02.2018
Former [2018/37]AT18.10.2017
CZ18.10.2017
DK18.10.2017
EE18.10.2017
FI18.10.2017
HR18.10.2017
LT18.10.2017
LV18.10.2017
PL18.10.2017
RS18.10.2017
SK18.10.2017
SM18.10.2017
BG18.01.2018
NO18.01.2018
GR19.01.2018
IS18.02.2018
Former [2018/35]AT18.10.2017
CZ18.10.2017
DK18.10.2017
EE18.10.2017
FI18.10.2017
HR18.10.2017
LT18.10.2017
LV18.10.2017
RS18.10.2017
SK18.10.2017
BG18.01.2018
NO18.01.2018
GR19.01.2018
IS18.02.2018
Former [2018/24]AT18.10.2017
FI18.10.2017
HR18.10.2017
LT18.10.2017
LV18.10.2017
RS18.10.2017
BG18.01.2018
NO18.01.2018
GR19.01.2018
IS18.02.2018
Former [2018/22]FI18.10.2017
LT18.10.2017
NO18.01.2018
Documents cited:Search[XY] WO2011038133  (DAVINCI BIOSCIENCES LLC et al.) [X] 1,4,6,7,9,10,13-15 * the whole document * * claims 1-33 * * page 1, line 12 - page 3, line 15 * * figures 1, 2 * * page 5, lines 12-23; examples 1-3 *[Y] 1-15
 [XY] WO2006019357  (CELLRES CORP PTE LTD et al.) [X] 10,11,13-15 * the whole document * * example 2 * * page 20, paragraphs [0071], [0072], [0073]; example 2 * * page 22, paragraph [0080]; figure 9 *[Y] 1-15
 [Y] CN101890050  (UNIV JIANGSU et al.) [Y] 1-15 * the whole document *
 [XP]   AMIT N. PATEL ET AL: "Mesenchymal Stem Cell Population Isolated From the Subepithelial Layer of Umbilical Cord Tissue", CELL TRANSPLANTATION, vol. 22, no. 3, 12 September 2012 (2012-09-12), pages 513 - 519, XP055181229, ISSN: 0963-6897, DOI: 10.3727/096368912X655064 [XP] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.3727/096368912X655064
 [XY]   JESCHKE M G ET AL: "Umbilical cord lining membrane and wharton's jelly-derived mesenchymal stem cells: The similarities and differences", OPEN TISSUE ENGINEERING AND REGENERATIVE MEDICINE JOURNAL 2011 BENTHAM SCIENCE PUBLISHERS B.V. NLD,, vol. 4, no. SPEC. ISSUE 1, 1 January 2011 (2011-01-01), pages 21 - 27, XP002696906, ISSN: 1875-0435 [X] 1,4,6,7,9 * the whole document * * page 22, column r, paragraph l - page 22, column r, paragraph 1 * * 3. SUB-AMNION-DERIVED CELLS; page 23, column l, paragraph 3 - column r, paragraph 2 * * page 23; table 1 *[Y] 1-15

DOI:   http://dx.doi.org/10.2174/1875043501104010021
 [XY]   KITA K ET AL: "Isolation and characterization of mesenchymal stem cells from the sub-amniotic human umbilical cord lining membrane", STEM CELLS AND DEVELOPMENT, MARY ANN LIEBERT, INC, NEW ROCHELLE, NY, US, vol. 19, no. 4, 1 April 2010 (2010-04-01), pages 491 - 502, XP002696905, ISSN: 1557-8534, [retrieved on 20090727], DOI: 10.1089/SCD.2009.0192 [X] 1,4,6,7,9-11,13-15 * the whole document * * page 492, column l, paragraph 2 - column r, paragraph 1 * * figure 1C * * page 494, column r, paragraph l - page 498, column l, paragraph 1 *[Y] 1-15

DOI:   http://dx.doi.org/10.1089/scd.2009.0192
 [XY]   TOBIAS DEUSE ET AL: "Immunogenicity and Immunomodulatory Properties of Umbilical Cord Lining Mesenchymal Stem Cells", CELL TRANSPLANTATION, vol. 20, no. 5, 1 May 2011 (2011-05-01), US, pages 655 - 667, XP055181577, ISSN: 0963-6897, DOI: 10.3727/096368910X536473 [X] 1,4,6,7,9 * the whole document * [Y] 1-15

DOI:   http://dx.doi.org/10.3727/096368910X536473
 [Y]   CHIARA CAPELLI ET AL: "Minimally manipulated whole human umbilical cord is a rich source of clinical-grade human mesenchymal stromal cells expanded in human platelet lysate", CYTOTHERAPY, vol. 13, no. 7, 1 August 2011 (2011-08-01), GB, pages 786 - 801, XP055181970, ISSN: 1465-3249, DOI: 10.3109/14653249.2011.563294 [Y] 1-15 * the whole document * * page 787, column r, paragraphs 2-5 * * page 790, column r, paragraph l - page 792, column l, paragraph 1 * * page 795, column l, paragraph 2 - page 796, column l, paragraph 1 *

DOI:   http://dx.doi.org/10.3109/14653249.2011.563294
 [Y]   RUENN CHAI LAI ET AL: "Mesenchymal stem cell exosome: a novel stem cell-based therapy for cardiovascular disease", REGENERATIVE MEDICINE, vol. 6, no. 4, 1 July 2011 (2011-07-01), pages 481 - 492, XP055182152, ISSN: 1746-0751, DOI: 10.2217/rme.11.35 [Y] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.2217/rme.11.35
International search[A] US2011312091  (ZHAO BAONA et al.) [A]
 [A] US2010216237  (GANCHAS SOARES RITA ISABEL et al.) [A]
 [A] KR20090109575   [A]
 [A]   CAO, FU-JIANG ET AL.: "Human umbilical cord mesenchymal stem cells and the t reatment of spinal cord injury", CHINESE MEDICAL JOURNAL, vol. 122, no. 2, January 2009 (2009-01-01), pages 225 - 231, XP003031523 [A]
 [A]   QIAO, CHUN ET AL.: "Human mesenchymal stem cells isolated from the umbilical cord", CELL BIOLOGY INTERNATIONAL, vol. 32, no. 1, January 2008 (2008-01-01), pages 8 - 15, XP022489072 [A]

DOI:   http://dx.doi.org/10.1016/j.cellbi.2007.08.002
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