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Extract from the Register of European Patents

EP About this file: EP2639239

EP2639239 - Removal of Protein Aggregates from Biopharmaceutical Preparations in a Flow-Through Mode [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  13.07.2018
Database last updated on 08.10.2024
FormerThe patent has been granted
Status updated on  04.08.2017
FormerGrant of patent is intended
Status updated on  02.04.2017
Most recent event   Tooltip17.07.2020Lapse of the patent in a contracting state
New state(s): AL		published on 19.08.2020  [2020/34]
Applicant(s)For all designated states
Merck Patent GmbH
Frankfurter Strasse 250
64293 Darmstadt / DE
[2013/45]
Former [2013/38]For all designated states
EMD Millipore Corporation
290 Concord Road
Billerica, MA 01821 / US
Inventor(s)01 / Kozlov, Mikhail
c/o EMD Millipore Corporation
290 Concordia Road
Billerica, MA 01821 / US
02 / Cataldo, William
c/o EMD Millipore Corporation
290 Concordia Road
Billerica, MA 01821 / US
03 / Potty, Ajish
c/o EMD Millipore Corporation
290 Concordia Road
Billerica, MA 01821 / US
04 / Galipeau, Kevin
c/o EMD Millipore Corporation
290 Concordia Road
Billerica, MA 01821 / US
05 / Hamzik, James
c/o EMD Millipore Corporation
290 Concordia Road
Billerica, MA 01821 / US
06 / Umana, Joaquin
c/o EMD Millipore Corporation
290 Concordia Road
Billerica, MA 01821 / US
07 / Peeck, Lars
c/o EMD Millipore Corporation
290 Concordia Road
Billerica, MA 01821 / US
 [2017/36]
Former [2013/38]01 / Kozlov, Mikhail
c/o EMD Millipore Corporation
290 Concord Road
Billerica, MA 01821 / US
02 / Cataldo, William
c/o EMD Millipore Corporation
290 Concord Road
Billerica, MA 01821 / US
03 / Potty, Ajish
c/o EMD Millipore Corporation
290 Concord Road
Billerica, MA 01821 / US
04 / Galipeau, Kevin
c/o EMD Millipore Corporation
290 Concord Road
Billerica, MA 01821 / US
05 / Hamzik, James
c/o EMD Millipore Corporation
290 Concord Road
Billerica, MA 01821 / US
06 / Umana, Joaquin
c/o EMD Millipore Corporation
290 Concord Road
Billerica, MA 01821 / US
07 / Peeck, Lars
c/o EMD Millipore Corporation
290 Concord Road
Billerica, MA 01821 / US
Representative(s)Kirkham, Nicholas Andrew, et al
Graham Watt & Co. LLP
St. Botolph's House
7-9 St. Botolph's Road
Sevenoaks, Kent TN13 3AJ / GB
[2017/36]
Former [2013/38]Kirkham, Nicholas Andrew, et al
Graham Watt & Co. LLP
St. Botolph's House
7-9 St. Botolph's Road
Sevenoaks
Kent TN13 3AJ / GB
Application number, filing date13275053.012.03.2013
[2013/38]
Priority number, dateUS201261609533P12.03.2012         Original published format: US 201261609533 P
US201261666578P29.06.2012         Original published format: US 201261666578 P
[2013/38]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP2639239
Date:18.09.2013
Language:EN
[2013/38]
Type: A3 Search report 
No.:EP2639239
Date:20.11.2013
Language:EN
[2013/47]
Type: B1 Patent specification 
No.:EP2639239
Date:06.09.2017
Language:EN
[2017/36]
Search report(s)(Supplementary) European search report - dispatched on:EP21.10.2013
ClassificationIPC:C07K1/16, C07K1/18
[2017/17]
CPC:
B01D15/362 (EP,KR,US); C08F220/585 (EP,KR); C07K1/22 (US);
B01J39/20 (EP,KR,US); B01J39/26 (EP,US); B01J41/20 (EP,US);
B01J47/026 (EP,US); C07K1/165 (EP,US); C07K1/18 (EP,KR,US);
C07K16/00 (US); C08F220/56 (KR); C08F222/385 (KR);
B01D15/363 (EP,US); B01D15/3809 (EP,US) (-)
C-Set:
C08F220/585, C08F222/385 (EP);
B01D15/363, B01D15/362 (US,EP);
B01D15/3809, B01D15/362 (US,EP);
B01D15/3809, B01D15/363, B01D15/362 (EP,US)
Former IPC [2013/38]C07K1/16, B01D15/36, B01J20/26, B01J20/32, C07K1/18
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/36]
Former [2013/38]AL,  AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  RS,  SE,  SI,  SK,  SM,  TR 
TitleGerman:Beseitigung von Proteinaggregaten aus biopharmazeutischen Präparaten in einem Durchflussmodus[2013/38]
English:Removal of Protein Aggregates from Biopharmaceutical Preparations in a Flow-Through Mode[2013/38]
French:Élimination d'agrégats de protéines à partir de préparations biopharmaceutiques dans un mode de transfert[2013/38]
Examination procedure20.05.2014Amendment by applicant (claims and/or description)
20.05.2014Examination requested  [2014/26]
18.06.2015Despatch of a communication from the examining division (Time limit: M04)
23.10.2015Reply to a communication from the examining division
29.04.2016Despatch of a communication from the examining division (Time limit: M04)
07.09.2016Reply to a communication from the examining division
03.04.2017Communication of intention to grant the patent
25.07.2017Fee for grant paid
25.07.2017Fee for publishing/printing paid
25.07.2017Receipt of the translation of the claim(s)
Divisional application(s)EP17188443.0  / EP3312190
EP20176384.4
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  18.06.2015
Opposition(s)07.06.2018No opposition filed within time limit [2018/33]
Fees paidRenewal fee
10.03.2015Renewal fee patent year 03
10.03.2016Renewal fee patent year 04
10.03.2017Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU12.03.2013
AL06.09.2017
CY06.09.2017
DK06.09.2017
EE06.09.2017
FI06.09.2017
HR06.09.2017
LT06.09.2017
LV06.09.2017
MC06.09.2017
MK06.09.2017
PT06.09.2017
RO06.09.2017
RS06.09.2017
SM06.09.2017
TR06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
IS06.01.2018
LU12.03.2018
MT12.03.2018
[2020/34]
Former [2020/31]HU12.03.2013
CY06.09.2017
DK06.09.2017
EE06.09.2017
FI06.09.2017
HR06.09.2017
LT06.09.2017
LV06.09.2017
MC06.09.2017
MK06.09.2017
PT06.09.2017
RO06.09.2017
RS06.09.2017
SM06.09.2017
TR06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
IS06.01.2018
LU12.03.2018
MT12.03.2018
Former [2020/27]HU12.03.2013
DK06.09.2017
EE06.09.2017
FI06.09.2017
HR06.09.2017
LT06.09.2017
LV06.09.2017
MC06.09.2017
PT06.09.2017
RO06.09.2017
RS06.09.2017
SM06.09.2017
TR06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
IS06.01.2018
LU12.03.2018
MT12.03.2018
Former [2020/16]DK06.09.2017
EE06.09.2017
FI06.09.2017
HR06.09.2017
LT06.09.2017
LV06.09.2017
MC06.09.2017
RO06.09.2017
RS06.09.2017
SM06.09.2017
TR06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
IS06.01.2018
LU12.03.2018
MT12.03.2018
Former [2020/08]DK06.09.2017
EE06.09.2017
FI06.09.2017
HR06.09.2017
LT06.09.2017
LV06.09.2017
MC06.09.2017
RO06.09.2017
RS06.09.2017
SM06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
IS06.01.2018
LU12.03.2018
MT12.03.2018
Former [2019/04]DK06.09.2017
EE06.09.2017
FI06.09.2017
HR06.09.2017
LT06.09.2017
LV06.09.2017
MC06.09.2017
RO06.09.2017
RS06.09.2017
SM06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
IS06.01.2018
LU12.03.2018
Former [2018/52]DK06.09.2017
EE06.09.2017
FI06.09.2017
HR06.09.2017
LT06.09.2017
LV06.09.2017
MC06.09.2017
RO06.09.2017
RS06.09.2017
SM06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
IS06.01.2018
Former [2018/35]DK06.09.2017
EE06.09.2017
FI06.09.2017
HR06.09.2017
LT06.09.2017
LV06.09.2017
RO06.09.2017
RS06.09.2017
SM06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
IS06.01.2018
Former [2018/24]EE06.09.2017
FI06.09.2017
HR06.09.2017
LT06.09.2017
LV06.09.2017
RO06.09.2017
RS06.09.2017
SM06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
IS06.01.2018
Former [2018/12]FI06.09.2017
HR06.09.2017
LT06.09.2017
LV06.09.2017
RS06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
Former [2018/11]FI06.09.2017
HR06.09.2017
LT06.09.2017
RS06.09.2017
BG06.12.2017
NO06.12.2017
GR07.12.2017
Former [2018/08]FI06.09.2017
LT06.09.2017
NO06.12.2017
Former [2018/07]LT06.09.2017
NO06.12.2017
Documents cited:Search[A]WO2005042131  (AMERSHAM BIOSCIENCES AB [SE], et al) [A] 1-12,14,15 * table 1 *;
 [XD]WO2010098867  (MILLIPORE CORP [US], et al) [XD] 1-12,14,15 * whole document, in particular claims 40, 45, paragraph [072] *;
 [A]WO2012015908  (MILLIPORE CORP [US], et al) [A] 1-12,14,15 * figure 1e; example 29; table 4 *;
 [A]WO2012013682  (UCB PHARMA SA [BE], et al) [A] 1-12,14,15 * examples 1,2 *;
 [A]  - MARINA URMANN ET AL, "Influence of protein and stationary phase properties on proteinmatrix-interaction in cation exchange chromatography", JOURNAL OF CHROMATOGRAPHY, ELSEVIER SCIENCE PUBLISHERS B.V, NL, vol. 1218, no. 31, doi:10.1016/J.CHROMA.2011.05.085, ISSN 0021-9673, (20110523), pages 5136 - 5145, (20110530), XP028236727 [A] 1-12,14,15 * table 1 *

DOI:   http://dx.doi.org/10.1016/j.chroma.2011.05.085
ExaminationUS6783937
 DE102006061327
 WO2008113460
 WO2010133527
 US2011136925
    - TANG ET AL, "Novel cell sheet carriers using polyion complex gel modified membranes for tissue engineering technology for cell sheet manipulation and transplantation", REACTIVE & FUNCTIONAL POLYMERS, ELSEVIER SCIENCE PUBLISHERS BV, NL, (20071016), vol. 67, no. 11, doi:10.1016/J.REACTFUNCTPOLYM.2007.07.058, ISSN 1381-5148, pages 1388 - 1397, XP022300764

DOI:   http://dx.doi.org/10.1016/j.reactfunctpolym.2007.07.058
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.