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Extract from the Register of European Patents

EP About this file: EP2802350

EP2802350 - CONTROLLED DELIVERY OF TLR AGONISTS IN STRUCTURAL POLYMERIC DEVICES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  26.10.2018
Database last updated on 07.03.2026
FormerThe patent has been granted
Status updated on  17.11.2017
FormerGrant of patent is intended
Status updated on  08.11.2017
FormerExamination is in progress
Status updated on  18.10.2017
FormerGrant of patent is intended
Status updated on  22.06.2017
Most recent event   Tooltip17.07.2020Lapse of the patent in a contracting state
New state(s): AL		published on 19.08.2020  [2020/34]
Applicant(s)For all designated states
President and Fellows of Harvard College
17 Quincy Street
Cambridge, MA 02138 / US
For all designated states
Dana-Farber Cancer Institute, Inc.
450 Brookline Avenue
Boston, MA 02215 / US
[2017/51]
Former [2014/47]For all designated states
President and Fellows of Harvard College
17 Quincy Street
Cambridge, MA 02138 / US
For all designated states
Dana-Farber Cancer Institute, Inc.
450 Brookline Avenue
Boston, MA 02215 / US
Inventor(s)01 / ALI, Omar, Abdel-Rahman
700 Huron Ave., Apt. 15
Cambridge, MA 02138 / US
02 / DRANOFF, Glenn
28 Outlook Drive
Lexington, MA 02421 / US
03 / MOONEY, David, J.
27 Powers Road
Sudbury, MA 01776 / US
 [2014/47]
Representative(s)Lock, Graham James, et al
Fry Heath & Spence LLP
Unit A, Faraday Court
Faraday Road
Crawley, West Sussex RH10 9PU / GB
[2017/51]
Former [2014/47]Mintz Levin Cohn Ferris Glovsky and Popeo LLP
Alder Castle
10 Noble Street
London EC2V 7JX / GB
Application number, filing date13702535.914.01.2013
[2017/51]
WO2013US21478
Priority number, dateUS201261586624P13.01.2012         Original published format: US 201261586624 P
[2014/47]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2013106852
Date:18.07.2013
Language:EN
[2013/29]
Type: A1 Application with search report 
No.:EP2802350
Date:19.11.2014
Language:EN
The application published by WIPO in one of the EPO official languages on 18.07.2013 takes the place of the publication of the European patent application.
[2014/47]
Type: B1 Patent specification 
No.:EP2802350
Date:20.12.2017
Language:EN
[2017/51]
Search report(s)International search report - published on:EP18.07.2013
ClassificationIPC:A61K39/39, A61K9/16
[2014/47]
CPC:
A61K39/0011 (EP,US); A61K9/1647 (EP); A61P35/00 (EP);
A61K2039/54 (EP); A61K2039/55522 (EP); A61K2039/55555 (EP);
A61K2039/55561 (EP); Y02A50/30 (EP) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2014/47]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:KONTROLLIERTE ABGABE VON TLR-AGONISTEN IN STRUKTURIERTEN POLYMEREN VORRICHTUNGEN[2014/47]
English:CONTROLLED DELIVERY OF TLR AGONISTS IN STRUCTURAL POLYMERIC DEVICES[2014/47]
French:ADMINISTRATION RÉGULÉE D'AGONISTES DE TLR DANS DES DISPOSITIFS POLYMÈRES STRUCTURAUX[2014/47]
Entry into regional phase12.08.2014National basic fee paid 
12.08.2014Designation fee(s) paid 
12.08.2014Examination fee paid 
Examination procedure12.08.2014Examination requested  [2014/47]
02.04.2015Amendment by applicant (claims and/or description)
15.07.2016Despatch of a communication from the examining division (Time limit: M02)
16.09.2016Reply to a communication from the examining division
23.06.2017Communication of intention to grant the patent
18.10.2017Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
18.10.2017Fee for grant paid
18.10.2017Fee for publishing/printing paid
08.11.2017Information about intention to grant a patent
08.11.2017Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  15.07.2016
Opposition(s)21.09.2018No opposition filed within time limit [2018/48]
Fees paidRenewal fee
27.01.2015Renewal fee patent year 03
27.01.2016Renewal fee patent year 04
27.01.2017Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU14.01.2013
AL20.12.2017
AT20.12.2017
CY20.12.2017
CZ20.12.2017
DK20.12.2017
EE20.12.2017
ES20.12.2017
FI20.12.2017
HR20.12.2017
IT20.12.2017
LT20.12.2017
LV20.12.2017
MC20.12.2017
MK20.12.2017
NL20.12.2017
PL20.12.2017
PT20.12.2017
RO20.12.2017
RS20.12.2017
SE20.12.2017
SI20.12.2017
SK20.12.2017
SM20.12.2017
TR20.12.2017
IE14.01.2018
LU14.01.2018
MT14.01.2018
BE31.01.2018
CH31.01.2018
LI31.01.2018
BG20.03.2018
NO20.03.2018
GR21.03.2018
IS20.04.2018
[2020/34]
Former [2020/31]HU14.01.2013
AT20.12.2017
CY20.12.2017
CZ20.12.2017
DK20.12.2017
EE20.12.2017
ES20.12.2017
FI20.12.2017
HR20.12.2017
IT20.12.2017
LT20.12.2017
LV20.12.2017
MC20.12.2017
MK20.12.2017
NL20.12.2017
PL20.12.2017
PT20.12.2017
RO20.12.2017
RS20.12.2017
SE20.12.2017
SI20.12.2017
SK20.12.2017
SM20.12.2017
TR20.12.2017
IE14.01.2018
LU14.01.2018
MT14.01.2018
BE31.01.2018
CH31.01.2018
LI31.01.2018
BG20.03.2018
NO20.03.2018
GR21.03.2018
IS20.04.2018
Former [2020/28]HU14.01.2013
AT20.12.2017
CY20.12.2017
CZ20.12.2017
DK20.12.2017
EE20.12.2017
ES20.12.2017
FI20.12.2017
HR20.12.2017
IT20.12.2017
LT20.12.2017
LV20.12.2017
MC20.12.2017
NL20.12.2017
PL20.12.2017
PT20.12.2017
RO20.12.2017
RS20.12.2017
SE20.12.2017
SI20.12.2017
SK20.12.2017
SM20.12.2017
TR20.12.2017
IE14.01.2018
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MT14.01.2018
BE31.01.2018
CH31.01.2018
LI31.01.2018
BG20.03.2018
NO20.03.2018
GR21.03.2018
IS20.04.2018
Former [2020/16]AT20.12.2017
CY20.12.2017
CZ20.12.2017
DK20.12.2017
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FI20.12.2017
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IT20.12.2017
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IE14.01.2018
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MT14.01.2018
BE31.01.2018
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BG20.03.2018
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Former [2020/08]AT20.12.2017
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FI20.12.2017
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IE14.01.2018
LU14.01.2018
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BG20.03.2018
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GR21.03.2018
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Former [2019/35]AT20.12.2017
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CZ20.12.2017
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EE20.12.2017
ES20.12.2017
FI20.12.2017
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NL20.12.2017
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RO20.12.2017
RS20.12.2017
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SI20.12.2017
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IE14.01.2018
LU14.01.2018
BE31.01.2018
CH31.01.2018
LI31.01.2018
BG20.03.2018
NO20.03.2018
GR21.03.2018
IS20.04.2018
Former [2019/13]AT20.12.2017
CY20.12.2017
CZ20.12.2017
DK20.12.2017
EE20.12.2017
FI20.12.2017
HR20.12.2017
IT20.12.2017
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PL20.12.2017
RO20.12.2017
RS20.12.2017
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SI20.12.2017
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IE14.01.2018
LU14.01.2018
BE31.01.2018
CH31.01.2018
LI31.01.2018
BG20.03.2018
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GR21.03.2018
IS20.04.2018
Former [2019/09]AT20.12.2017
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DK20.12.2017
EE20.12.2017
FI20.12.2017
HR20.12.2017
IT20.12.2017
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MC20.12.2017
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PL20.12.2017
RO20.12.2017
RS20.12.2017
SE20.12.2017
SK20.12.2017
SM20.12.2017
IE14.01.2018
LU14.01.2018
BE31.01.2018
CH31.01.2018
LI31.01.2018
BG20.03.2018
NO20.03.2018
GR21.03.2018
IS20.04.2018
Former [2018/51]AT20.12.2017
CY20.12.2017
CZ20.12.2017
DK20.12.2017
EE20.12.2017
FI20.12.2017
HR20.12.2017
IT20.12.2017
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MC20.12.2017
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PL20.12.2017
RO20.12.2017
RS20.12.2017
SE20.12.2017
SK20.12.2017
SM20.12.2017
LU14.01.2018
BE31.01.2018
CH31.01.2018
LI31.01.2018
BG20.03.2018
NO20.03.2018
GR21.03.2018
IS20.04.2018
Former [2018/50]AT20.12.2017
CY20.12.2017
CZ20.12.2017
EE20.12.2017
FI20.12.2017
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IT20.12.2017
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LU14.01.2018
BE31.01.2018
BG20.03.2018
NO20.03.2018
GR21.03.2018
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Former [2018/47]AT20.12.2017
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EE20.12.2017
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LU14.01.2018
BG20.03.2018
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Former [2018/44]AT20.12.2017
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BG20.03.2018
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Former [2018/39]AT20.12.2017
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EE20.12.2017
FI20.12.2017
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RS20.12.2017
SE20.12.2017
SK20.12.2017
SM20.12.2017
BG20.03.2018
NO20.03.2018
GR21.03.2018
IS20.04.2018
Former [2018/38]AT20.12.2017
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EE20.12.2017
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HR20.12.2017
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SM20.12.2017
BG20.03.2018
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Cited inInternational search[X]   KRISHNAMACHARI YOGITA ET AL: "PLGA microparticles that co-deliver antigen and toll like receptor ligand adjuvants for applications in cancer immunotherapy", INTERNET CITATION, 11 November 2009 (2009-11-11), pages 1, XP002670678, Retrieved from the Internet [retrieved on 20120301]
 [Y]   AIALA SALVADOR ET AL: "Combination of immune stimulating adjuvants with poly(lactide-co-glycolide) microspheres enhances the immune response of vaccines", VACCINE, ELSEVIER LTD, GB, vol. 30, no. 3, 15 November 2011 (2011-11-15), pages 589 - 596, XP028348171, ISSN: 0264-410X, [retrieved on 20111122], DOI: 10.1016/J.VACCINE.2011.11.057

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 [Y]   MARIE-LUCE DE TEMMERMAN ET AL: "Particulate vaccines: on the quest for optimal delivery and immune response", DRUG DISCOVERY TODAY, vol. 16, no. 13, July 2011 (2011-07-01), pages 569 - 582, XP028231719, ISSN: 1359-6446, [retrieved on 20110504], DOI: 10.1016/J.DRUDIS.2011.04.006

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DOI:   http://dx.doi.org/10.1016/j.addr.2011.05.021
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