EP2807151 - APOPTOSIS SIGNAL-REGULATING KINASE INHIBITOR [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 23.09.2016 Database last updated on 27.07.2024 | Most recent event Tooltip | 23.09.2016 | No opposition filed within time limit | published on 26.10.2016 [2016/43] | Applicant(s) | For all designated states Gilead Sciences, Inc. 333 Lakeside Drive Foster City, CA 94404 / US | [2014/49] | Inventor(s) | 01 /
NOTTE, Gregory 21 Otay Avenue San Mateo, CA 94403 / US | [2014/49] | Representative(s) | Lumsden, Stuart Edward Henry Marks & Clerk LLP 90 Long Acre London WC2E 9RA / GB | [2015/47] |
Former [2014/49] | Lumsden, Stuart Edward Henry Marks & Clerk LLP 90 Long Acre GB-London WC2E 9RA / GB | Application number, filing date | 13703675.2 | 24.01.2013 | [2015/47] | WO2013US22997 | Priority number, date | US201261591710P | 27.01.2012 Original published format: US 201261591710 P | [2014/49] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2013112741 | Date: | 01.08.2013 | Language: | EN | [2013/31] | Type: | A1 Application with search report | No.: | EP2807151 | Date: | 03.12.2014 | Language: | EN | The application published by WIPO in one of the EPO official languages on 01.08.2013 takes the place of the publication of the European patent application. | [2014/49] | Type: | B1 Patent specification | No.: | EP2807151 | Date: | 18.11.2015 | Language: | EN | [2015/47] | Search report(s) | International search report - published on: | EP | 01.08.2013 | Classification | IPC: | C07D233/56, C07D401/04, C07D401/14, A61K31/4436, A61K31/4164, A61P31/12 | [2014/49] | CPC: |
C07D401/14 (EP,CN,KR,US);
A61K31/4164 (KR);
A61K31/4436 (KR);
A61K31/4439 (EP,US);
A61K45/06 (US);
A61K9/0053 (US);
A61K9/20 (US);
A61P1/16 (EP);
A61P11/00 (EP);
A61P13/12 (EP);
A61P19/04 (EP);
A61P3/10 (EP);
A61P31/00 (EP);
A61P31/12 (EP);
A61P43/00 (EP);
A61P9/00 (EP);
C07D213/56 (EP,US);
C07D233/56 (EP,CN,KR,US);
C07D401/04 (EP,CN,KR,US)
(-)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2014/49] | Extension states | BA | 31.07.2014 | ME | 31.07.2014 | Title | German: | APOPTOSESIGNALREGULIERENDER KINASEHEMMER | [2014/49] | English: | APOPTOSIS SIGNAL-REGULATING KINASE INHIBITOR | [2014/49] | French: | INHIBITEUR DE LA KINASE RÉGULANT LES SIGNAUX DE L'APOPTOSE | [2014/49] | Entry into regional phase | 31.07.2014 | National basic fee paid | 31.07.2014 | Designation fee(s) paid | 31.07.2014 | Examination fee paid | Examination procedure | 31.07.2014 | Examination requested [2014/49] | 23.02.2015 | Amendment by applicant (claims and/or description) | 21.05.2015 | Communication of intention to grant the patent | 30.09.2015 | Fee for grant paid | 30.09.2015 | Fee for publishing/printing paid | 30.09.2015 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 21.05.2015 | Opposition(s) | 19.08.2016 | No opposition filed within time limit [2016/43] | Fees paid | Renewal fee | 27.01.2015 | Renewal fee patent year 03 |
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Former [2016/25] | LV | 18.11.2015 | Cited in | International search | [A]WO2011008709 (GILEAD SCIENCES INC [US], et al) [A] 1-12 * the whole document *; | [A]WO2012003387 (GILEAD SCIENCES INC [US], et al) [A] 1-12* the whole document * | by applicant | US2007276050 | WO2009027283 | US2011009410 | - ICHIJO, H.; NISHIDA, E.; IRIE, K.; DIJKE, P. T.; SAITOH, M.; MORIGUCHI, T.; MATSUMOTO, K.; MIYAZONO, K.; GOTOH, Y., SCIENCE, (1997), vol. 275, pages 90 - 94 | - HATTORI, K.; NAGURO, I.; RUNCHEL, C.; ICHIJO, H., CELL COMM. SIGNAL., (2009), vol. 7, pages 1 - 10 | - TAKEDA, K.; NOGUCHI, T.; NAGURO, I.; ICHIJO, H., ANNU. REV. PHARMACOL. TOXICOL., (2007), vol. 48, pages 1 - 8,27 | - NAGAI, H.; NOGUCHI, T.; TAKEDA, K.; ICHIJO, I., J. BIOCHEM. MOL. BIOL., (2007), vol. 40, pages 1 - 6 | - WATANABE ET AL., BBRC, (2005), vol. 333, pages 562 - 567 | - ZHANG ET AL., LIFE SCI, (2003), vol. 74, pages 37 - 43 | - TERADA ET AL., BBRC, (2007), vol. 364, pages 1043 - 49 | - SINGH DK; WINOCOUR P; FARRINGTON K., "Oxidative stress in early diabetic nephropathy: fueling the fire", NAT REV ENDOCRINOL, (201103), vol. 7, no. 3, pages 176 - 184 | - BROWNLEE M., "Biochemistry and molecular cell biology of diabetic complications", NATURE, (20011213), vol. 414, no. 6865, pages 813 - 820 | - MIMURA I; NANGAKU M.; 2010 NOV, "The suffocating kidney: tubulointerstitial hypoxia in end-stage renal disease", NAT REV NEPHROL, vol. 6, no. 11, pages 667 - 678 | - HUNG KY ET AL., "N- acetylcysteine-mediated antioxidation prevents hyperglycemia-induced apoptosis and collagen synthesis in rat mesangial cells", AM JNEPHROL, (2009), vol. 29, no. 3, pages 192 - 202 | - SCHAINUCK LI ET AL., "Structural-functional correlations in renal disease. Part II: The correlations", HUM PATHOL, (1970), vol. 1, pages 631 - 641 | - CHEVALIER ET AL., "Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy", KIDNEY INTERNATIONAL, (2009), vol. 75, pages 1145 - 1152 | - DE B, I ET AL., "Temporal trends in the prevalence of diabetic kidney disease in the United States", JAMA, (20110622), vol. 305, no. 24, pages 2532 - 2539 | - BERGE, JOURNAL OFPHARMACEUTICAL SCIENCE, (197701), vol. 66, no. 1 | - G.S. BANKER & C.T. RHODES,, Modern Pharmaceutics 3rd Ed., MARCEL DEKKER, INC. | - STAMBE ET AL., "The Role ofp38 Mitogen-Activated Protein Kinase Activation in Renal Fibrosis", JAM SOC NEPHROL, (2004), vol. 15, pages 370 - 379 |