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Extract from the Register of European Patents

EP About this file: EP2828295

EP2828295 - ANTI-IL-1BETA AGENT FOR USE IN THE TREATMENT OR THE PREVENTION OF AORTIC ANEURYSM [Right-click to bookmark this link]
Former [2015/05]METHOD AND PHARMACEUTICAL COMPOSITION FOR USE IN THE TREATMENT OR THE PREVENTION OF ANEURYSM
[2017/36]
StatusThe application is deemed to be withdrawn
Status updated on  29.06.2018
Database last updated on 19.10.2024
FormerGrant of patent is intended
Status updated on  21.09.2017
FormerExamination is in progress
Status updated on  11.01.2017
Most recent event   Tooltip29.06.2018Application deemed to be withdrawnpublished on 01.08.2018  [2018/31]
Applicant(s)For all designated states
INSERM (Institut National de la Santé et de la Recherche Médicale)
101, rue de Tolbiac
75013 Paris / FR
For all designated states
Université Paris Descartes
12, rue de l'Ecole de Médecine
75006 Paris / FR
[2017/42]
Former [2015/05]For all designated states
INSERM - Institut National de la Santé et de la Recherche Médicale
101, rue de Tolbiac
75013 Paris / FR
For all designated states
Université Paris Descartes
12, rue de l'Ecole de Médecine
75006 Paris / FR
Inventor(s)01 / MALLAT, Ziad
U970 PARCC
GH Georges Pompidou Broussais
56 rue Leblanc
75015 Paris / FR
02 / TALEB, Soraya
U970 PARCC
GH Georges Pompidou Broussais
56 rue Leblanc
75015 Paris / FR
03 / TEDGUI, Alain
U970 PARCC
GH Georges Pompidou Broussais
56 rue Leblanc
75015 Paris / FR
[N/P]
Former [2015/05]01 / MALLAT, Ziad
U970 Parcc
GH Georges Pompidou Broussais
56 rue Leblanc
F-75015 Paris / FR
02 / TALEB, Soraya
U970 Parcc
GH Georges Pompidou Broussais
56 rue Leblanc
F-75015 Paris / FR
03 / TEDGUI, Alain
U970 Parcc
GH Georges Pompidou Broussais
56 rue Leblanc
F-75015 Paris / FR
Representative(s)Hirsch, Denise Marie
Inserm Transfert IP Department 7 rue Watt
75013 Paris / FR
[2015/05]
Application number, filing date13709446.215.03.2013
WO2013EP55385
Priority number, dateEP2012030532319.03.2012         Original published format: EP 12305323
[2015/05]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2013139701
Date:26.09.2013
Language:EN
[2013/39]
Type: A1 Application with search report 
No.:EP2828295
Date:28.01.2015
Language:EN
The application published by WIPO in one of the EPO official languages on 26.09.2013 takes the place of the publication of the European patent application.
[2015/05]
Search report(s)International search report - published on:EP26.09.2013
ClassificationIPC:C07K16/24, A61P9/00
[2015/05]
CPC:
C07K16/245 (EP,US); A61K38/2006 (EP,US); A61P43/00 (EP);
A61P9/00 (EP); A61P9/14 (EP); A61K2039/505 (EP,US);
C07K2317/76 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2015/05]
TitleGerman:ANTI-IL-1BETA MITTEL ZUR VERWENDUNG BEI DER BEHANDLUNG ODER VORBEUGUNG VON AORTENANEURYSMEN[2017/36]
English:ANTI-IL-1BETA AGENT FOR USE IN THE TREATMENT OR THE PREVENTION OF AORTIC ANEURYSM[2017/36]
French:AGENT CONTRE IL-1BETA DESTINÉ À ÊTRE UTILISÉ DANS LE TRAITEMENT OU LA PRÉVENTION D'UN ANÉURISME AORTIQUE[2017/36]
Former [2015/05]VERFAHREN UND PHARMAZEUTISCHE ZUSAMMENSETZUNG ZUR VERWENDUNG BEI DER BEHANDLUNG ODER VORBEUGUNG VON ANEURYSMEN
Former [2015/05]METHOD AND PHARMACEUTICAL COMPOSITION FOR USE IN THE TREATMENT OR THE PREVENTION OF ANEURYSM
Former [2015/05]MÉTHODE ET COMPOSITION PHARMACEUTIQUE DESTINÉE À ÊTRE UTILISÉE DANS LE TRAITEMENT OU LA PRÉVENTION D'UN ANÉVRISME
Entry into regional phase03.09.2014National basic fee paid 
03.09.2014Designation fee(s) paid 
03.09.2014Examination fee paid 
Examination procedure03.09.2014Amendment by applicant (claims and/or description)
03.09.2014Examination requested  [2015/05]
11.08.2015Despatch of a communication from the examining division (Time limit: M06)
22.02.2016Reply to a communication from the examining division
12.10.2016Despatch of a communication from the examining division (Time limit: M06)
05.04.2017Reply to a communication from the examining division
22.09.2017Communication of intention to grant the patent
03.02.2018Application deemed to be withdrawn, date of legal effect  [2018/31]
13.03.2018Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time  [2018/31]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  11.08.2015
Fees paidRenewal fee
24.03.2015Renewal fee patent year 03
23.03.2016Renewal fee patent year 04
23.03.2017Renewal fee patent year 05
Penalty fee
Additional fee for renewal fee
31.03.201806   M06   Not yet paid
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Cited inInternational search[I]  - MORIWAKI TAKUYA ET AL, "Impaired progression of cerebral aneurysms in interleukin-1 beta-deficient mice", STROKE, (200603), vol. 37, no. 3, ISSN 0039-2499, pages 900 - 905, XP009162227 [I] 1-3 * the whole document * * in particular abstract figures *

DOI:   http://dx.doi.org/10.1161/​01.STR.0000204028.39783.d9
 [I]  - LEE YOUNGHO ET AL, "Interleukin-1[beta] is crucial for the induction of coronary artery inflammation in a mouse model of Kawasaki disease", CIRCULATION, LIPPINCOT WILLIAMS AND WILKINS, BALTIMORE, US, (20120223), vol. 125, no. 12, ISSN 1524-4539, pages 1542 - 1550, XP009162210 [I] 1-3 * abstract * * published online February 23, 2012 *

DOI:   http://dx.doi.org/10.1161/CIRCULATIONAHA.111.072769
 [A]  - LEI ZHANG ET AL, "Overexpression of interleukin-1 and interferon- in type I thoracic aortic dissections and ascending thoracic aortic aneurysms: possible correlation with matrix metalloproteinase-9 expression and apoptosis of aortic media cells", EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, SPRINGER VERLAG, BERLIN, DE, vol. 40, no. 1, doi:10.1016/J.EJCTS.2010.09.019, ISSN 1010-7940, (20100905), pages 17 - 22, (20100917), XP028228425 [A] 1-3 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.ejcts.2010.09.019
 [A]  - WANG YU ET AL, "TGF-beta activity protects against inflammatory aortic aneurysm progression and complications in angiotensin II-infused mice", JOURNAL OF CLINICAL INVESTIGATION, (201002), vol. 120, no. 2, ISSN 0021-9738, pages 422 - 432, XP009162240 [A] 1-3 * the whole document *
Examination   - CHURCH LEIGH D ET AL, "Canakinumab: a human anti-IL-1[beta] monoclonal antibody for the treatment of cryopyrin-associated periodic syndromes.", EXPERT REVIEW OF CLINICAL IMMUNOLOGY NOV 2010, (201011), vol. 6, no. 6, ISSN 1744-8409, pages 831 - 841, XP009185686

DOI:   http://dx.doi.org/10.1586/eci.10.66
    - HUMPHREY J D ET AL, "Intracranial and abdominal aortic aneurysms: similarities, differences, and need for a new class of computational models.", ANNUAL REVIEW OF BIOMEDICAL ENGINEERING 2008, (2008), vol. 10, ISSN 1523-9829, pages 221 - 246
    - ZAMBROWICZ BRIAN P ET AL, "Knockouts model the 100 best-selling drugs--will they model the next 100?", NATURE REVIEWS. DRUG DISCOVERY JAN 2003, (200301), vol. 2, no. 1, doi:doi:10.1038/nrd987, ISSN 1474-1776, pages 38 - 51, XP002451004

DOI:   http://dx.doi.org/10.1038/nrd987
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.