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Extract from the Register of European Patents

EP About this file: EP2836506

EP2836506 - MUTANT LYSENIN PORES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  23.02.2018
Database last updated on 08.06.2024
FormerThe patent has been granted
Status updated on  17.03.2017
FormerGrant of patent is intended
Status updated on  04.03.2017
Most recent event   Tooltip17.07.2020Lapse of the patent in a contracting state
New state(s): AL		published on 19.08.2020  [2020/34]
Applicant(s)For all designated states
Oxford Nanopore Technologies Limited
Edmund Cartwright House
4 Robert Robinson Avenue
Oxford Science Park
Oxford OX4 4GA / GB
[2017/16]
Former [2015/08]For all designated states
Oxford Nanopore Technologies Limited
Edmund Cartwright House
4 Robert Robinson Avenue
Oxford Science Park
Oxford OX4 4GA / GB
Inventor(s)01 / BRUCE, Mark
Oxford Nanopore Technologies Limited
Edmund Cartwright House
4 Robert Robinson Avenue
Oxford Science Park
Oxford Oxfordshire OX4 4GA / GB
02 / CLARKE, James
Oxford Nanopore Technolgies Limited
Edmund Cartwright House
4 Robert Robinson Avenue
Oxford Science Park
Oxford Oxfordshire OX4 4GA / GB
03 / HERON, Andrew
Oxford Nanopore Technologies Limited
Edmund Cartwright House
4 Robert Robinson Avenue
Oxford Science Park
Oxford Oxfordshire OX4 4GA / GB
04 / JAYASINGHE, Lakmal
Oxford Nanopore Technologies Limited
Edmund Cartwright House
4 Robert Robinson Avenue
Oxford Science Park
Oxford Oxfordshire OX4 4GA / GB
05 / WALLACE, Elizabeth Jayne
Oxford Nanopore Technologies Limited
Edmund Cartwright House
4 Robert Robinson Avenue
Oxford Science Park
Oxford Oxfordshire OX4 4GA / GB
 [2017/13]
Former [2015/08]01 / BRUCE, Mark
Oxford Nanopore Technologies Limited
Edmund Cartwright House
4 Robert Robinson Avenue
Oxford Science Park
Oxford Oxfordshire OX4 4GA / GB
02 / CLARKE, James
Oxford Nanopore Technolgies Limited
Edmund Cartwright House
4 Robert Robinson Avenue
Oxford Science Park
Oxford Oxfordshire OX4 4GA / GB
03 / HERON, Andrew
Oxford Nanopore Technologies Limited
Edmund Cartwright House
4 Robert Robinson Avenue
Oxford Science Park
Oxford Oxfordshire OX4 4GA / GB
04 / JAYASINGHE, Lakmal
Oxford Nanopore Technologies Limited
Edmund Cartwright House
4 Robert Robinson Avenue
Oxford Science Park
Oxford Oxfordshire OX4 4GA / GB
05 / WALLACE, Jayne
Oxford Nanopore Technologies Limited
Edmund Cartwright House
4 Robert Robinson Avenue
Oxford Science Park
Oxford Oxfordshire OX4 4GA / GB
Representative(s)J A Kemp LLP
80 Turnmill Street
London EC1M 5QU / GB
[N/P]
Former [2017/16]Tuxworth, Pamela M.
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Former [2015/08]Chapman, Lee Phillip
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Application number, filing date13711464.115.03.2013
[2017/16]
WO2013GB50667
Priority number, dateUS201261622174P10.04.2012         Original published format: US 201261622174 P
[2015/08]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2013153359
Date:17.10.2013
Language:EN
[2013/42]
Type: A1 Application with search report 
No.:EP2836506
Date:18.02.2015
Language:EN
The application published by WIPO in one of the EPO official languages on 17.10.2013 takes the place of the publication of the European patent application.
[2015/08]
Type: B1 Patent specification 
No.:EP2836506
Date:19.04.2017
Language:EN
[2017/16]
Search report(s)International search report - published on:EP17.10.2013
ClassificationIPC:C07K14/435, C12Q1/00
[2015/08]
CPC:
C07K14/43536 (EP,CN,US); C12Q1/6869 (EP,CN,US); G01N27/447 (US);
C07K2319/55 (US)
C-Set:
C12Q1/6869, C12Q2565/631 (CN)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2015/08]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:LYSENIN MUTANT POREN[2016/45]
English:MUTANT LYSENIN PORES[2015/08]
French:PORES DE MUTANTS DE LYSENIN[2016/45]
Former [2015/08]MUTANTE LYSENINPOREN
Former [2015/08]PORES FORMÉS DE LYSENINE MUTANTE
Entry into regional phase06.11.2014National basic fee paid 
06.11.2014Designation fee(s) paid 
06.11.2014Examination fee paid 
Examination procedure06.11.2014Examination requested  [2015/08]
17.07.2015Despatch of communication that the application is deemed to be withdrawn, reason: reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report not received in time
17.07.2015Despatch of communication of loss of particular rights: Claims {1}
24.09.2015Amendment by applicant (claims and/or description)
12.02.2016Despatch of a communication from the examining division (Time limit: M04)
10.06.2016Reply to a communication from the examining division
25.10.2016Communication of intention to grant the patent
01.03.2017Fee for grant paid
01.03.2017Fee for publishing/printing paid
01.03.2017Receipt of the translation of the claim(s)
Divisional application(s)EP17157441.1  / EP3192804
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  12.02.2016
Opposition(s)22.01.2018No opposition filed within time limit [2018/13]
Request for further processing for:24.09.2015Request for further processing filed
24.09.2015Full payment received (date of receipt of payment)
Request granted
07.10.2015Decision despatched
Fees paidRenewal fee
10.03.2015Renewal fee patent year 03
10.03.2016Renewal fee patent year 04
10.03.2017Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU15.03.2013
AL19.04.2017
AT19.04.2017
CY19.04.2017
CZ19.04.2017
DK19.04.2017
EE19.04.2017
ES19.04.2017
FI19.04.2017
HR19.04.2017
IT19.04.2017
LT19.04.2017
LV19.04.2017
MC19.04.2017
MK19.04.2017
PL19.04.2017
PT19.04.2017
RO19.04.2017
RS19.04.2017
SE19.04.2017
SI19.04.2017
SK19.04.2017
SM19.04.2017
TR19.04.2017
BG19.07.2017
NO19.07.2017
GR20.07.2017
IS19.08.2017
[2020/34]
Former [2020/31]HU15.03.2013
AT19.04.2017
CY19.04.2017
CZ19.04.2017
DK19.04.2017
EE19.04.2017
ES19.04.2017
FI19.04.2017
HR19.04.2017
IT19.04.2017
LT19.04.2017
LV19.04.2017
MC19.04.2017
MK19.04.2017
PL19.04.2017
PT19.04.2017
RO19.04.2017
RS19.04.2017
SE19.04.2017
SI19.04.2017
SK19.04.2017
SM19.04.2017
TR19.04.2017
BG19.07.2017
NO19.07.2017
GR20.07.2017
IS19.08.2017
Former [2020/30]HU15.03.2013
AT19.04.2017
CZ19.04.2017
DK19.04.2017
EE19.04.2017
ES19.04.2017
FI19.04.2017
HR19.04.2017
IT19.04.2017
LT19.04.2017
LV19.04.2017
MC19.04.2017
PL19.04.2017
PT19.04.2017
RO19.04.2017
RS19.04.2017
SE19.04.2017
SI19.04.2017
SK19.04.2017
SM19.04.2017
TR19.04.2017
BG19.07.2017
NO19.07.2017
GR20.07.2017
IS19.08.2017
Former [2020/28]AT19.04.2017
CZ19.04.2017
DK19.04.2017
EE19.04.2017
ES19.04.2017
FI19.04.2017
HR19.04.2017
IT19.04.2017
LT19.04.2017
LV19.04.2017
MC19.04.2017
PL19.04.2017
PT19.04.2017
RO19.04.2017
RS19.04.2017
SE19.04.2017
SI19.04.2017
SK19.04.2017
SM19.04.2017
TR19.04.2017
BG19.07.2017
NO19.07.2017
GR20.07.2017
IS19.08.2017
Former [2020/15]AT19.04.2017
CZ19.04.2017
DK19.04.2017
EE19.04.2017
ES19.04.2017
FI19.04.2017
HR19.04.2017
IT19.04.2017
LT19.04.2017
LV19.04.2017
MC19.04.2017
PL19.04.2017
RO19.04.2017
RS19.04.2017
SE19.04.2017
SI19.04.2017
SK19.04.2017
SM19.04.2017
TR19.04.2017
BG19.07.2017
NO19.07.2017
GR20.07.2017
IS19.08.2017
Former [2018/52]AT19.04.2017
CZ19.04.2017
DK19.04.2017
EE19.04.2017
ES19.04.2017
FI19.04.2017
HR19.04.2017
IT19.04.2017
LT19.04.2017
LV19.04.2017
MC19.04.2017
PL19.04.2017
RO19.04.2017
RS19.04.2017
SE19.04.2017
SI19.04.2017
SK19.04.2017
SM19.04.2017
BG19.07.2017
NO19.07.2017
GR20.07.2017
IS19.08.2017
Former [2018/25]AT19.04.2017
CZ19.04.2017
DK19.04.2017
EE19.04.2017
ES19.04.2017
FI19.04.2017
HR19.04.2017
IT19.04.2017
LT19.04.2017
LV19.04.2017
PL19.04.2017
RO19.04.2017
RS19.04.2017
SE19.04.2017
SI19.04.2017
SK19.04.2017
SM19.04.2017
BG19.07.2017
NO19.07.2017
GR20.07.2017
IS19.08.2017
Former [2018/11]AT19.04.2017
CZ19.04.2017
DK19.04.2017
EE19.04.2017
ES19.04.2017
FI19.04.2017
HR19.04.2017
IT19.04.2017
LT19.04.2017
LV19.04.2017
PL19.04.2017
RO19.04.2017
RS19.04.2017
SE19.04.2017
SK19.04.2017
SM19.04.2017
BG19.07.2017
NO19.07.2017
GR20.07.2017
IS19.08.2017
Former [2018/10]AT19.04.2017
CZ19.04.2017
DK19.04.2017
EE19.04.2017
ES19.04.2017
FI19.04.2017
HR19.04.2017
LT19.04.2017
LV19.04.2017
PL19.04.2017
RO19.04.2017
RS19.04.2017
SE19.04.2017
SK19.04.2017
BG19.07.2017
NO19.07.2017
GR20.07.2017
IS19.08.2017
Former [2018/09]AT19.04.2017
DK19.04.2017
EE19.04.2017
ES19.04.2017
FI19.04.2017
HR19.04.2017
LT19.04.2017
LV19.04.2017
PL19.04.2017
RS19.04.2017
SE19.04.2017
BG19.07.2017
NO19.07.2017
GR20.07.2017
IS19.08.2017
Former [2017/50]AT19.04.2017
ES19.04.2017
FI19.04.2017
HR19.04.2017
LT19.04.2017
LV19.04.2017
PL19.04.2017
RS19.04.2017
SE19.04.2017
BG19.07.2017
NO19.07.2017
GR20.07.2017
IS19.08.2017
Former [2017/49]AT19.04.2017
ES19.04.2017
FI19.04.2017
HR19.04.2017
LT19.04.2017
NO19.07.2017
GR20.07.2017
IS19.08.2017
Cited inInternational search[X]US2002168725  (KOBAYASHI TOSHIHIDE [JP], et al) [X] 1-7 * the whole document *;
 [I]  - TAKAAKI AOKI ET AL, "Single channel properties of lysenin measured in artificial lipid bilayers and their applications to biomolecule detection", PROCEEDINGS OF THE JAPAN ACADEMY, SERIES B, (20100101), vol. 86, no. 9, doi:10.2183/pjab.86.920, ISSN 0386-2208, pages 920 - 925, XP055065726 [I] 1-7 * the whole document *

DOI:   http://dx.doi.org/10.2183/pjab.86.920
 [A]  - DANIEL FOLOGEA ET AL, "Potential analytical applications of lysenin channels for detection of multivalent ions", ANALYTICAL AND BIOANALYTICAL CHEMISTRY, SPRINGER, BERLIN, DE, (20110805), vol. 401, no. 6, doi:10.1007/S00216-011-5277-8, ISSN 1618-2650, pages 1871 - 1879, XP019951845 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1007/s00216-011-5277-8
 [A]  - IDE T ET AL, "Lysenin forms a voltage-dependent channel in artificial lipid bilayer membranes", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 346, no. 1, doi:10.1016/J.BBRC.2006.05.115, ISSN 0006-291X, (20060721), pages 288 - 292, (20060721), XP024925317 [A] 1-50 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.bbrc.2006.05.115
 [AP]  - SKOÄAJ ET AL, "The sensing of membrane microdomains based on pore-forming toxins.", CURRENT MEDICINAL CHEMISTRY, (20130101), vol. 20, no. 4, ISSN 0929-8673, pages 491 - 501, XP055066940 [AP] 1-50 * the whole document *
 [AP]  - LUIGI DE COLIBUS ET AL, "Structures of Lysenin Reveal a Shared Evolutionary Origin for Pore-Forming Proteins And Its Mode of Sphingomyelin Recognition", STRUCTURE, (20120901), vol. 20, no. 9, doi:10.1016/j.str.2012.06.011, ISSN 0969-2126, pages 1498 - 1507, XP055066958 [AP] 1-50 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.str.2012.06.011
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.