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Extract from the Register of European Patents

EP About this file: EP2864342

EP2864342 - 1,1'-[[(SUBSTITUTED ALKYL)IMINO]BIS(ALKYLENE)]BIS-FERROCENES AND THEIR USE IN ELECTROCHEMICAL ASSAYS BY LABELLING SUBSTRATES OF INTEREST [Right-click to bookmark this link]
Former [2015/18]1,1 '-[[(SUBSTITUTED ALKYL)IMINO]BIS(ALKYLENE)]BIS-FERROCENES AND THEIR USE IN I ELECTROCHEMICAL ASSAYS BY LABELLING SUBSTRATES OF INTEREST
[2020/43]
StatusNo opposition filed within time limit
Status updated on  10.06.2022
Database last updated on 05.10.2024
FormerThe patent has been granted
Status updated on  02.07.2021
FormerGrant of patent is intended
Status updated on  12.04.2021
FormerExamination is in progress
Status updated on  16.02.2021
FormerGrant of patent is intended
Status updated on  19.10.2020
FormerExamination is in progress
Status updated on  15.06.2018
Most recent event   Tooltip06.09.2024Lapse of the patent in a contracting state
New state(s): MT		published on 09.10.2024 [2024/41]
Applicant(s)For all designated states
Binx Health Limited
Derby Court Epsom Square
White Horse Business Park
Trowbridge
BA14 0XG / GB
[2021/26]
Former [2015/18]For all designated states
Atlas Genetics Limited
Derby Court Epsom Square
White Horse Business Park
Trowbridge, Wiltshire BA14 0XG / GB
Inventor(s)01 / MARSH, Barrie
c/o Atlas Genetics Limited
Derby Court
Epsom Square
White Horse Business Park
Trowbridge Wiltshire BA14 0XG / GB
02 / FROST, Christopher
c/o University of Bath
Claverton Down
Bath
Bath and North East Somerset BA14 7AY / GB
03 / PEARCE, David
c/o Altas Genetics Limited
Derby Court
Epsom Square
White Horse Business Park
Trowbridge Wiltshire BA14 0XG / GB
 [2015/18]
Representative(s)Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[2015/18]
Application number, filing date13731474.621.06.2013
[2021/31]
WO2013GB51643
Priority number, dateGB2012001115722.06.2012         Original published format: GB 201211157
[2015/18]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2013190328
Date:27.12.2013
Language:EN
[2013/52]
Type: A1 Application with search report 
No.:EP2864342
Date:29.04.2015
Language:EN
The application published by WIPO in one of the EPO official languages on 27.12.2013 takes the place of the publication of the European patent application.
[2015/18]
Type: B1 Patent specification 
No.:EP2864342
Date:04.08.2021
Language:EN
[2021/31]
Search report(s)International search report - published on:EP27.12.2013
ClassificationIPC:C07F17/02, C12Q1/68, G01N27/00, C12Q1/6816
[2020/43]
CPC:
C07F17/02 (EP,CN,US); G01N33/58 (US); C12Q1/6816 (EP,CN,US)
C-Set:
C12Q1/6816, C12Q2563/113 (CN,EP,US)
Former IPC [2015/18]C07F17/02, C12Q1/68, G01N27/00
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2015/18]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:1,1'-[[(SUBSTITUIERTE ALKYL)IMINO](BIS)(ALKYLEN)]BIS-FERROCENE UND DEREN VERWENDUNG BEI ELEKTROCHEMISCHEN TESTVERFAHREN DURCH MARKIERUNG VON BESTIMMTEN SUBSTRATEN[2015/18]
English:1,1'-[[(SUBSTITUTED ALKYL)IMINO]BIS(ALKYLENE)]BIS-FERROCENES AND THEIR USE IN ELECTROCHEMICAL ASSAYS BY LABELLING SUBSTRATES OF INTEREST[2020/43]
French:1,1'-[[(ALKYLE SUBSTITUÉ)IMINO]BIS(ALKYLÈNE)]BIS-FERROCÈNES ET LEUR UTILISATION DANS DES DOSAGES ÉLECTROCHIMIQUES PAR MARQUAGE DE SUBSTRATS D'INTÉRÊT[2015/18]
Former [2015/18]1,1 '-[[(SUBSTITUTED ALKYL)IMINO]BIS(ALKYLENE)]BIS-FERROCENES AND THEIR USE IN I ELECTROCHEMICAL ASSAYS BY LABELLING SUBSTRATES OF INTEREST
Entry into regional phase19.01.2015National basic fee paid 
19.01.2015Designation fee(s) paid 
19.01.2015Examination fee paid 
Examination procedure19.01.2015Amendment by applicant (claims and/or description)
19.01.2015Examination requested  [2015/18]
14.06.2018Despatch of a communication from the examining division (Time limit: M06)
31.01.2019Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
10.04.2019Reply to a communication from the examining division
24.04.2020Despatch of a communication from the examining division (Time limit: M04)
03.09.2020Reply to a communication from the examining division
20.10.2020Communication of intention to grant the patent
15.02.2021Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
13.04.2021Communication of intention to grant the patent
13.05.2021Fee for grant paid
13.05.2021Fee for publishing/printing paid
13.05.2021Receipt of the translation of the claim(s)
Divisional application(s)EP21188839.1  / EP3974435
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  14.06.2018
Opposition(s)06.05.2022No opposition filed within time limit [2022/28]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
10.04.2019Request for further processing filed
10.04.2019Full payment received (date of receipt of payment)
Request granted
25.04.2019Decision despatched
Fees paidRenewal fee
10.06.2015Renewal fee patent year 03
10.06.2016Renewal fee patent year 04
16.06.2017Renewal fee patent year 05
11.06.2018Renewal fee patent year 06
27.06.2019Renewal fee patent year 07
29.06.2020Renewal fee patent year 08
28.06.2021Renewal fee patent year 09
Opt-out from the exclusive  Tooltip
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU21.06.2013
AL04.08.2021
AT04.08.2021
CY04.08.2021
CZ04.08.2021
DK04.08.2021
EE04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
MC04.08.2021
MK04.08.2021
MT04.08.2021
NL04.08.2021
PL04.08.2021
RO04.08.2021
RS04.08.2021
SE04.08.2021
SI04.08.2021
SK04.08.2021
SM04.08.2021
TR04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
[2024/41]
Former [2024/29]HU21.06.2013
AL04.08.2021
AT04.08.2021
CY04.08.2021
CZ04.08.2021
DK04.08.2021
EE04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
MC04.08.2021
MK04.08.2021
NL04.08.2021
PL04.08.2021
RO04.08.2021
RS04.08.2021
SE04.08.2021
SI04.08.2021
SK04.08.2021
SM04.08.2021
TR04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
Former [2024/22]HU21.06.2013
AL04.08.2021
AT04.08.2021
CY04.08.2021
CZ04.08.2021
DK04.08.2021
EE04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
MC04.08.2021
MK04.08.2021
NL04.08.2021
PL04.08.2021
RO04.08.2021
RS04.08.2021
SE04.08.2021
SI04.08.2021
SK04.08.2021
SM04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
Former [2024/20]HU21.06.2013
AL04.08.2021
AT04.08.2021
CY04.08.2021
CZ04.08.2021
DK04.08.2021
EE04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
MC04.08.2021
NL04.08.2021
PL04.08.2021
RO04.08.2021
RS04.08.2021
SE04.08.2021
SI04.08.2021
SK04.08.2021
SM04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
Former [2024/18]HU21.06.2013
AL04.08.2021
AT04.08.2021
CZ04.08.2021
DK04.08.2021
EE04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
MC04.08.2021
NL04.08.2021
PL04.08.2021
RO04.08.2021
RS04.08.2021
SE04.08.2021
SI04.08.2021
SK04.08.2021
SM04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
Former [2023/08]AL04.08.2021
AT04.08.2021
CZ04.08.2021
DK04.08.2021
EE04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
MC04.08.2021
NL04.08.2021
PL04.08.2021
RO04.08.2021
RS04.08.2021
SE04.08.2021
SI04.08.2021
SK04.08.2021
SM04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
Former [2022/36]AL04.08.2021
AT04.08.2021
CZ04.08.2021
DK04.08.2021
EE04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
NL04.08.2021
PL04.08.2021
RO04.08.2021
RS04.08.2021
SE04.08.2021
SI04.08.2021
SK04.08.2021
SM04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
Former [2022/29]AL04.08.2021
AT04.08.2021
CZ04.08.2021
DK04.08.2021
EE04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
NL04.08.2021
PL04.08.2021
RO04.08.2021
RS04.08.2021
SE04.08.2021
SK04.08.2021
SM04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
Former [2022/26]AT04.08.2021
CZ04.08.2021
DK04.08.2021
EE04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
NL04.08.2021
PL04.08.2021
RO04.08.2021
RS04.08.2021
SE04.08.2021
SK04.08.2021
SM04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
Former [2022/24]AT04.08.2021
CZ04.08.2021
DK04.08.2021
EE04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
NL04.08.2021
PL04.08.2021
RO04.08.2021
RS04.08.2021
SE04.08.2021
SK04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
Former [2022/21]AT04.08.2021
DK04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
NL04.08.2021
PL04.08.2021
RS04.08.2021
SE04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
Former [2022/16]AT04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
NL04.08.2021
PL04.08.2021
RS04.08.2021
SE04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
Former [2022/10]AT04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
PL04.08.2021
RS04.08.2021
SE04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
Former [2022/09]AT04.08.2021
FI04.08.2021
LT04.08.2021
RS04.08.2021
SE04.08.2021
BG04.11.2021
NO04.11.2021
PT06.12.2021
Former [2022/08]AT04.08.2021
FI04.08.2021
LT04.08.2021
SE04.08.2021
BG04.11.2021
NO04.11.2021
Former [2022/07]AT04.08.2021
LT04.08.2021
NO04.11.2021
Cited inInternational search[A]WO2005005657  (MOLECULAR SENSING PLC [GB], et al) [A] 1-54 * page 8; compounds formula I, IIa * * page 23; example 3b * * Method of detection,using eletrochemically active marker:;; claims 1-9 *;
 [A]WO2011073675  (ATLAS GENETICS LTD [GB], et al) [A] 1-54 * page 34; compounds Formula VII, VIII * * Method of detecting genetic material using electrochemically active marker:;; claims 1-5 *;
 [IP]WO2012085591  (ATLAS GENETICS LTD [GB], et al) [IP] 1-54* page 46, column left, line 1; claim 30; compounds Bromo-compound *;
 [X]  - HU, XIANG PING ET AL, "Synthesis and potential application of novel C2-symmetrical bis(ferrocenyl) P2N ligand", CA, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, Database accession no. 2004:39098, URL: STN, XP002713991 [X] 13-17,24-29,31,35,37,38 * abstract * * (2R,2''R)-1,1''-[(methylimino)di-(1R)-ethylidiene]bis[2-(diphenylphosphino)-ferrocene *
 [X]  - DONG-JEI CHO ET AL, "Chiral C2-symmetric bisferrocenyldiamines as ligands for transition metal catalyzed asymmetric cyclopropanation and aziridination", TETRAHEDRON: ASYMMETRY, (1999), vol. 10, no. 19, doi:10.1016/S0957-4166(99)00423-1, ISSN 0957-4166, pages 3833 - 3848, XP055081769 [X] 13-17,24-29,31,35,37,38 * compounds 3a, 3c *

DOI:   http://dx.doi.org/10.1016/S0957-4166(99)00423-1
 [X]  - MARTIN LAMAČ ET AL, "Preparation of planar-chiral multidonor phosphanylferrocene carboxamides and their application as ligands for palladium-catalysed asymmetric allylic alkylation", APPLIED ORGANOMETALLIC CHEMISTRY, (20100122), doi:10.1002/aoc.1616, ISSN 0268-2605, pages n/a - n/a, XP055081777 [X] 13-17,24-29,31,35,37,38 * Scheme 1:;; compound 5 *

DOI:   http://dx.doi.org/10.1002/aoc.1616
 [X]  - KUHNERT J ET AL, "Phosphinoferrocenyl-terminated amidoamines: Synthesis and catalytic utilization in palladium-mediated C-C bond forming reactions", JOURNAL OF MOLECULAR CATALYSIS A: CHEMICAL, ELSEVIER, AMSTERDAM, NL, vol. 285, no. 1-2, doi:10.1016/J.MOLCATA.2008.01.026, ISSN 1381-1169, (20080418), pages 41 - 47, (20080120), XP022656042 [X] 13-17,24-29,31,35,37,38 * compound P3 *

DOI:   http://dx.doi.org/10.1016/j.molcata.2008.01.026
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.