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Extract from the Register of European Patents

EP About this file: EP2802872

EP2802872 - MECHANICAL BIOMARKERS FOR OOCYTE AND EMBRYO VIABILITY [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  13.04.2018
Database last updated on 03.09.2024
FormerGrant of patent is intended
Status updated on  04.07.2017
FormerExamination is in progress
Status updated on  20.03.2017
Most recent event   Tooltip13.04.2018Application deemed to be withdrawnpublished on 16.05.2018  [2018/20]
Applicant(s)For all designated states
The Board of Trustees of the Leland Stanford Junior University
1705 El Camino Real
Palo Alto, CA 94306 / US
[N/P]
Former [2014/47]For all designated states
The Board of Trustees of the Leland Stanford Junior University
1705 El Camino Real
Palo Alto, CA 94306 / US
Inventor(s)01 / ZARNESCU, Livia
446 Grant Avenue
Palo Alto, California 94306 / US
02 / CAMARILLO, David, B.
186 Seacliff Drive
Aptos, California 95003 / US
03 / HAN, Jinnuo
439 Del Medio Avenue-Apt. 13
Mountain View, California 94040 / US
04 / PERA, Renee, Reijo, A.
298 Cuesta Drive
Los Altos, California 94022 / US
05 / CHAVEZ, Shawn, L.
4128 Margery Drive
Fremont, California 94538 / US
06 / BEHR, Barry
2039 Barbara Drive
Palo Alto, California 94303 / US
 [2014/47]
Representative(s)Teall, Charlotte
Forresters IP LLP
Skygarden
Erika-Mann-Strasse 11
80636 München / DE
[N/P]
Former [2014/47]Teall, Charlotte
Forresters
Skygarden
Erika-Mann-Strasse 11
80636 München / DE
Application number, filing date13736056.611.01.2013
WO2013US21292
Priority number, dateUS201261586561P13.01.2012         Original published format: US 201261586561 P
[2014/47]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2013106753
Date:18.07.2013
Language:EN
[2013/29]
Type: A1 Application with search report 
No.:EP2802872
Date:19.11.2014
Language:EN
The application published by WIPO in one of the EPO official languages on 18.07.2013 takes the place of the publication of the European patent application.
[2014/47]
Search report(s)International search report - published on:KR18.07.2013
(Supplementary) European search report - dispatched on:EP11.08.2015
ClassificationIPC:G01N33/483, A61B17/435, C12M3/00, C12M1/42, C12M1/34, G01N33/68
[2017/27]
CPC:
G01N33/4833 (EP,US); A61B17/435 (EP,US); C12M21/06 (EP,US);
C12M35/04 (EP,US); C12M41/46 (EP,US); G01N33/689 (EP,US);
G01N33/483 (EP,US) (-)
Former IPC [2014/47]G01N33/483, G01N33/48
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2014/47]
TitleGerman:MECHANISCHE BIOMARKER FÜR DIE LEBENSFÄHIGKEIT VON OOZYTEN UND EMBRYOS[2014/47]
English:MECHANICAL BIOMARKERS FOR OOCYTE AND EMBRYO VIABILITY[2014/47]
French:BIOMARQUEURS MÉCANIQUES POUR LA VIABILITÉ D'UN OVOCYTE ET D'UN EMBRYON[2014/47]
Entry into regional phase11.08.2014National basic fee paid 
11.08.2014Search fee paid 
11.08.2014Designation fee(s) paid 
11.08.2014Examination fee paid 
Examination procedure11.08.2014Examination requested  [2014/47]
23.02.2016Amendment by applicant (claims and/or description)
14.10.2016Despatch of a communication from the examining division (Time limit: M04)
11.05.2017Reply to a communication from the examining division
05.07.2017Communication of intention to grant the patent
16.11.2017Application deemed to be withdrawn, date of legal effect  [2018/20]
03.01.2018Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time  [2018/20]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  14.10.2016
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
11.05.2017Request for further processing filed
11.05.2017Full payment received (date of receipt of payment)
Request granted
24.05.2017Decision despatched
Fees paidRenewal fee
27.04.2015Renewal fee patent year 03
01.01.2016Renewal fee patent year 04
30.01.2017Renewal fee patent year 05
Penalty fee
Additional fee for renewal fee
31.01.201503   M06   Fee paid on   27.04.2015
31.01.201806   M06   Not yet paid
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[XI]  - M. KHALILIAN ET AL, "Estimating Young's modulus of zona pellucida by micropipette aspiration in combination with theoretical models of ovum", REVIEWS IN ENDOCRINE AND METABOLIC DISORDERS, (20091014), vol. 3, no. 1, doi:10.1023/A:1012744617241, ISSN 1389-9155, pages 19 - 694, XP055159451 [X] 1-3,6,11,13-15 * page 688, column l, lines 31-44 * * Sections 2.3-2.5 * [I] 4,5,7-10,12

DOI:   http://dx.doi.org/10.1098/rsif.2009.0380
 [X]  - XINYU LIU ET AL, "In-situ mechanical characterization of mouse oocytes using a cell holding device", MICRO ELECTRO MECHANICAL SYSTEMS (MEMS), 2010 IEEE 23RD INTERNATIONAL CONFERENCE ON, IEEE, PISCATAWAY, NJ, USA, (20100124), ISBN 978-1-4244-5761-8, pages 947 - 950, XP031655084 [X] 1,14 * Section "Device, Design, Fabrication, and Calibration" * * Section "Force Analysis" *
 [A]  - J. D. PAJEROWSKI ET AL, "Physical plasticity of the nucleus in stem cell differentiation", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, (20071002), vol. 104, no. 40, doi:10.1073/pnas.0702576104, ISSN 0027-8424, pages 15619 - 15624, XP055159457 [A] 1-15 * abstract * * Section "Plastic Flow of Nuclei and Nucleoli Maps into Chromatin Fiber" *

DOI:   http://dx.doi.org/10.1073/pnas.0702576104
 [A]  - FARSHID GUILAK ET AL, "Viscoelastic Properties of the Cell Nucleus", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, (20000324), vol. 269, no. 3, doi:10.1006/bbrc.2000.2360, ISSN 0006-291X, pages 781 - 786, XP055206084 [A] 1-15 * Section "Isolation of culture of cells" * * Section "Viscoleastic testing" * * Section "Results";; figure 4 *

DOI:   http://dx.doi.org/10.1006/bbrc.2000.2360
 [A]  - MURAYAMA Y ET AL, "Micro-mechanical sensing platform for the characterization of the elastic properties of the ovum via uniaxial measurement", JOURNAL OF BIOMECHANICS, PERGAMON PRESS, NEW YORK, NY, US, (20040101), vol. 37, no. 1, doi:10.1016/S0021-9290(03)00242-2, ISSN 0021-9290, pages 67 - 72, XP004895597 [A] 1-15 * abstract *

DOI:   http://dx.doi.org/10.1016/S0021-9290(03)00242-2
 [A]  - YOSHINOBU MURAYAMA ET AL, "Elasticity Measurement of Zona Pellucida Using a Micro Tactile Sensor to Evaluate Embryo Quality", JOURNAL OF MAMMALIAN OVA RESEARCH, (200804), vol. 25, no. 1, doi:10.1274/jmor.25.8, ISSN 1341-7738, pages 8 - 16, XP055206006 [A] 1-15 * Section "Conclusion" *

DOI:   http://dx.doi.org/10.1274/jmor.25.8
International search[X]  - KHALILIAN ET AL., "Estimating young' s modulus of zona pellucia by micropipette aspiration in combination with theoretical models of ovem", JOURNAL OF THE RORAL SOCIETY, (2010), vol. 7, no. 45, pages 687 - 694, XP055159451

DOI:   http://dx.doi.org/10.1098/rsif.2009.0380
 [A]  - MOHR ET AL., "The use of fluorescein diacetate to assess embryo viability in the mouse", JOURNAL OF REPRODUCTION AND FERTILITY, (1980), vol. 58, no. 1, pages 189 - 196, XP055159452

DOI:   http://dx.doi.org/10.1530/jrf.0.0580189
 [A]  - KONG ET AL., "Comparison of open pulled straw (OPS) vs glass micropipette (GMP) vitrification in mouse blastocysts", THERIOGENOLOGY, (2000), vol. 53, no. 9, pages 1817 - 1826, XP055159454
 [A]  - VAZIRI ET AL., "Mechanics and deformation of the nucleus in micropipette aspiration experiment", JOURNAL OF BIOMECHANICS, (2007), vol. 40, no. 9, pages 2053 - 2062, XP022104131
 [A]  - PAJEROWSKI ET AL., "Physical plasticity of the nucleus in stem cell differentiation", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, (2007), vol. 104, no. 40, pages 15619 - 15624, XP055159457

DOI:   http://dx.doi.org/10.1073/pnas.0702576104
by applicant   - BEHR ET AL., HUMAN REPRODUCTION, (1999), vol. 14, no. 2, pages 454 - 7
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.