EP2870152 - AMIDE OR UREA SUBSTITUTED BENZOTHIAZOLE DERIVATIVES AS INHIBITORS OF ENDOTHELIAL LIPASE [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 04.08.2017 Database last updated on 02.08.2024 | Most recent event Tooltip | 06.03.2020 | Lapse of the patent in a contracting state New state(s): TR | published on 08.04.2020 [2020/15] | Applicant(s) | For all designated states Bristol-Myers Squibb Company Route 206 and Province Line Road Princeton, NJ 08543 / US | [2015/20] | Inventor(s) | 01 /
PI, Zulan c/o Bristol-Myers Squibb Company 311 Pennington-Rocky Hill Road Pennington, New Jersey 08534 / US | 02 /
QIAO, Jennifer X. c/o Bristol-Myers Squibb Company 311 Pennington-Rocky Hill Road Pennington, New Jersey 08534 / US | 03 /
TORA, George O. c/o Bristol-Myers Squibb Company 311 Pennington-Rocky Hill Road Pennington, New Jersey 08534 / US | 04 /
WANG, Tammy C. c/o Bristol-Myers Squibb Company 311 Pennington-Rocky Hill Road Pennington, New Jersey 08534 / US | [2015/20] | Representative(s) | Reitstötter Kinzebach Patentanwälte Sternwartstraße 4 81679 München / DE | [N/P] |
Former [2015/20] | Reitstötter Kinzebach Patentanwälte Sternwartstrasse 4 81679 München / DE | Application number, filing date | 13737767.7 | 03.07.2013 | [2016/39] | WO2013US49194 | Priority number, date | US201261669266P | 09.07.2012 Original published format: US 201261669266 P | [2015/20] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2014011461 | Date: | 16.01.2014 | Language: | EN | [2014/03] | Type: | A1 Application with search report | No.: | EP2870152 | Date: | 13.05.2015 | Language: | EN | The application published by WIPO in one of the EPO official languages on 16.01.2014 takes the place of the publication of the European patent application. | [2015/20] | Type: | B1 Patent specification | No.: | EP2870152 | Date: | 28.09.2016 | Language: | EN | [2016/39] | Search report(s) | International search report - published on: | EP | 16.01.2014 | Classification | IPC: | C07D417/06, C07D417/14, A61K31/428, A61K31/4439, A61K31/515, A61P3/06, A61P9/10, A61P9/12, A61P25/28 | [2015/20] | CPC: |
C07D417/14 (EP,US);
A61P25/28 (EP);
A61P3/06 (EP);
A61P9/10 (EP);
A61P9/12 (EP);
C07D417/06 (EP,US)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2015/20] | Extension states | BA | Not yet paid | ME | Not yet paid | Title | German: | AMID- ODER HARNSTOFF-SUBSTITUIERTE BENZOTHIAZOLDERIVATE ALS INHIBITOREN VON ENDOTHELLIPASE | [2016/14] | English: | AMIDE OR UREA SUBSTITUTED BENZOTHIAZOLE DERIVATIVES AS INHIBITORS OF ENDOTHELIAL LIPASE | [2015/20] | French: | DÉRIVÉS DE BENZOTHIAZOLE SUBSTITUÉES PAR UN GROUPE D'AMIDE OU D'URÉE EN TANT QU'INHIBITEURS DE LA LIPASE ENDOTHÉLIALE | [2016/14] |
Former [2015/20] | AMID- ODER HARNSTOFFSUBSTITUIERTE BENZOTHIAZOLDERIVATE ALS ENDOTHELLIPASEHEMMER | ||
Former [2015/20] | DÉRIVÉS DE BENZOTHIAZOLE SUBSTITUÉS PAR AMIDE OU URÉE EN TANT QU'INHIBITEURS DE LIPASE ENDOTHÉLIALE | Entry into regional phase | 03.02.2015 | National basic fee paid | 03.02.2015 | Designation fee(s) paid | 03.02.2015 | Examination fee paid | Examination procedure | 03.02.2015 | Examination requested [2015/20] | 28.09.2015 | Amendment by applicant (claims and/or description) | 19.04.2016 | Communication of intention to grant the patent | 16.08.2016 | Fee for grant paid | 16.08.2016 | Fee for publishing/printing paid | 16.08.2016 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 19.04.2016 | Opposition(s) | 29.06.2017 | No opposition filed within time limit [2017/36] | Fees paid | Renewal fee | 10.07.2015 | Renewal fee patent year 03 | 11.07.2016 | Renewal fee patent year 04 |
Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 03.07.2013 | AL | 28.09.2016 | AT | 28.09.2016 | BE | 28.09.2016 | CY | 28.09.2016 | CZ | 28.09.2016 | DK | 28.09.2016 | EE | 28.09.2016 | ES | 28.09.2016 | FI | 28.09.2016 | HR | 28.09.2016 | IT | 28.09.2016 | LT | 28.09.2016 | LV | 28.09.2016 | MC | 28.09.2016 | MK | 28.09.2016 | NL | 28.09.2016 | PL | 28.09.2016 | RO | 28.09.2016 | RS | 28.09.2016 | SE | 28.09.2016 | SI | 28.09.2016 | SK | 28.09.2016 | SM | 28.09.2016 | TR | 28.09.2016 | BG | 28.12.2016 | NO | 28.12.2016 | GR | 29.12.2016 | IS | 28.01.2017 | PT | 30.01.2017 | [2020/15] |
Former [2019/51] | HU | 03.07.2013 | |
AL | 28.09.2016 | ||
AT | 28.09.2016 | ||
BE | 28.09.2016 | ||
CY | 28.09.2016 | ||
CZ | 28.09.2016 | ||
DK | 28.09.2016 | ||
EE | 28.09.2016 | ||
ES | 28.09.2016 | ||
FI | 28.09.2016 | ||
HR | 28.09.2016 | ||
IT | 28.09.2016 | ||
LT | 28.09.2016 | ||
LV | 28.09.2016 | ||
MC | 28.09.2016 | ||
MK | 28.09.2016 | ||
NL | 28.09.2016 | ||
PL | 28.09.2016 | ||
RO | 28.09.2016 | ||
RS | 28.09.2016 | ||
SE | 28.09.2016 | ||
SI | 28.09.2016 | ||
SK | 28.09.2016 | ||
SM | 28.09.2016 | ||
BG | 28.12.2016 | ||
NO | 28.12.2016 | ||
GR | 29.12.2016 | ||
IS | 28.01.2017 | ||
PT | 30.01.2017 | ||
Former [2019/47] | HU | 03.07.2013 | |
AL | 28.09.2016 | ||
AT | 28.09.2016 | ||
BE | 28.09.2016 | ||
CY | 28.09.2016 | ||
CZ | 28.09.2016 | ||
DK | 28.09.2016 | ||
EE | 28.09.2016 | ||
ES | 28.09.2016 | ||
FI | 28.09.2016 | ||
HR | 28.09.2016 | ||
IT | 28.09.2016 | ||
LT | 28.09.2016 | ||
LV | 28.09.2016 | ||
MC | 28.09.2016 | ||
NL | 28.09.2016 | ||
PL | 28.09.2016 | ||
RO | 28.09.2016 | ||
RS | 28.09.2016 | ||
SE | 28.09.2016 | ||
SI | 28.09.2016 | ||
SK | 28.09.2016 | ||
SM | 28.09.2016 | ||
BG | 28.12.2016 | ||
NO | 28.12.2016 | ||
GR | 29.12.2016 | ||
IS | 28.01.2017 | ||
PT | 30.01.2017 | ||
Former [2019/31] | HU | 03.07.2013 | |
AL | 28.09.2016 | ||
AT | 28.09.2016 | ||
BE | 28.09.2016 | ||
CZ | 28.09.2016 | ||
DK | 28.09.2016 | ||
EE | 28.09.2016 | ||
ES | 28.09.2016 | ||
FI | 28.09.2016 | ||
HR | 28.09.2016 | ||
IT | 28.09.2016 | ||
LT | 28.09.2016 | ||
LV | 28.09.2016 | ||
MC | 28.09.2016 | ||
NL | 28.09.2016 | ||
PL | 28.09.2016 | ||
RO | 28.09.2016 | ||
RS | 28.09.2016 | ||
SE | 28.09.2016 | ||
SI | 28.09.2016 | ||
SK | 28.09.2016 | ||
SM | 28.09.2016 | ||
BG | 28.12.2016 | ||
NO | 28.12.2016 | ||
GR | 29.12.2016 | ||
IS | 28.01.2017 | ||
PT | 30.01.2017 | ||
Former [2019/30] | AL | 28.09.2016 | |
AT | 28.09.2016 | ||
BE | 28.09.2016 | ||
CZ | 28.09.2016 | ||
DK | 28.09.2016 | ||
EE | 28.09.2016 | ||
ES | 28.09.2016 | ||
FI | 28.09.2016 | ||
HR | 28.09.2016 | ||
IT | 28.09.2016 | ||
LT | 28.09.2016 | ||
LV | 28.09.2016 | ||
MC | 28.09.2016 | ||
NL | 28.09.2016 | ||
PL | 28.09.2016 | ||
RO | 28.09.2016 | ||
RS | 28.09.2016 | ||
SE | 28.09.2016 | ||
SI | 28.09.2016 | ||
SK | 28.09.2016 | ||
SM | 28.09.2016 | ||
BG | 28.12.2016 | ||
NO | 28.12.2016 | ||
GR | 29.12.2016 | ||
IS | 28.01.2017 | ||
PT | 30.01.2017 | ||
Former [2018/47] | AL | 28.09.2016 | |
AT | 28.09.2016 | ||
BE | 28.09.2016 | ||
CZ | 28.09.2016 | ||
DK | 28.09.2016 | ||
EE | 28.09.2016 | ||
ES | 28.09.2016 | ||
FI | 28.09.2016 | ||
HR | 28.09.2016 | ||
IT | 28.09.2016 | ||
LT | 28.09.2016 | ||
LV | 28.09.2016 | ||
NL | 28.09.2016 | ||
PL | 28.09.2016 | ||
RO | 28.09.2016 | ||
RS | 28.09.2016 | ||
SE | 28.09.2016 | ||
SI | 28.09.2016 | ||
SK | 28.09.2016 | ||
SM | 28.09.2016 | ||
BG | 28.12.2016 | ||
NO | 28.12.2016 | ||
GR | 29.12.2016 | ||
IS | 28.01.2017 | ||
PT | 30.01.2017 | ||
Former [2017/52] | AT | 28.09.2016 | |
BE | 28.09.2016 | ||
CZ | 28.09.2016 | ||
DK | 28.09.2016 | ||
EE | 28.09.2016 | ||
ES | 28.09.2016 | ||
FI | 28.09.2016 | ||
HR | 28.09.2016 | ||
IT | 28.09.2016 | ||
LT | 28.09.2016 | ||
LV | 28.09.2016 | ||
NL | 28.09.2016 | ||
PL | 28.09.2016 | ||
RO | 28.09.2016 | ||
RS | 28.09.2016 | ||
SE | 28.09.2016 | ||
SI | 28.09.2016 | ||
SK | 28.09.2016 | ||
SM | 28.09.2016 | ||
BG | 28.12.2016 | ||
NO | 28.12.2016 | ||
GR | 29.12.2016 | ||
IS | 28.01.2017 | ||
PT | 30.01.2017 | ||
Former [2017/34] | AT | 28.09.2016 | |
BE | 28.09.2016 | ||
CZ | 28.09.2016 | ||
DK | 28.09.2016 | ||
EE | 28.09.2016 | ||
ES | 28.09.2016 | ||
FI | 28.09.2016 | ||
HR | 28.09.2016 | ||
IT | 28.09.2016 | ||
LT | 28.09.2016 | ||
LV | 28.09.2016 | ||
NL | 28.09.2016 | ||
PL | 28.09.2016 | ||
RO | 28.09.2016 | ||
RS | 28.09.2016 | ||
SE | 28.09.2016 | ||
SK | 28.09.2016 | ||
SM | 28.09.2016 | ||
BG | 28.12.2016 | ||
NO | 28.12.2016 | ||
GR | 29.12.2016 | ||
IS | 28.01.2017 | ||
PT | 30.01.2017 | ||
Former [2017/32] | AT | 28.09.2016 | |
BE | 28.09.2016 | ||
CZ | 28.09.2016 | ||
EE | 28.09.2016 | ||
ES | 28.09.2016 | ||
FI | 28.09.2016 | ||
HR | 28.09.2016 | ||
IT | 28.09.2016 | ||
LT | 28.09.2016 | ||
LV | 28.09.2016 | ||
NL | 28.09.2016 | ||
PL | 28.09.2016 | ||
RO | 28.09.2016 | ||
RS | 28.09.2016 | ||
SE | 28.09.2016 | ||
SK | 28.09.2016 | ||
SM | 28.09.2016 | ||
BG | 28.12.2016 | ||
NO | 28.12.2016 | ||
GR | 29.12.2016 | ||
IS | 28.01.2017 | ||
PT | 30.01.2017 | ||
Former [2017/13] | FI | 28.09.2016 | |
HR | 28.09.2016 | ||
LT | 28.09.2016 | ||
LV | 28.09.2016 | ||
NL | 28.09.2016 | ||
RS | 28.09.2016 | ||
SE | 28.09.2016 | ||
NO | 28.12.2016 | ||
GR | 29.12.2016 | ||
Former [2017/11] | FI | 28.09.2016 | |
HR | 28.09.2016 | ||
LT | 28.09.2016 | ||
RS | 28.09.2016 | ||
SE | 28.09.2016 | ||
NO | 28.12.2016 | ||
GR | 29.12.2016 | ||
Former [2017/10] | FI | 28.09.2016 | |
HR | 28.09.2016 | ||
LT | 28.09.2016 | ||
RS | 28.09.2016 | ||
SE | 28.09.2016 | ||
NO | 28.12.2016 | ||
Former [2017/09] | FI | 28.09.2016 | |
LT | 28.09.2016 | ||
NO | 28.12.2016 | ||
Former [2017/07] | LT | 28.09.2016 | Cited in | International search | [A]CA2784710 (SHIONOGI & CO [JP]) [A] 1-12 * claim 1 *; | [AD]WO2012081563 (SHIONOGI & CO [JP], et al) [AD] 1-12* claim 1 * | by applicant | WO9932611 | WO2004093872 | WO2004094393 | WO2004094394 | US2006211755 | WO2007042178 | US7217727 | WO2007110215 | WO2007110216 | US2008287448 | US2009054478 | US2009076068 | US7595403 | WO2009123164 | WO2009133834 | WO2010044441 | WO2011074560 | US2011251386 | WO2012081563 | US2012253040 | WO2012173099 | - ROSS, R., NATURE, (1993), vol. 362, no. 6423, pages 801 - 809 | - GORDON, D.J. ET AL., N. ENGL. J. MED., (1989), vol. 321, no. 19, pages 1311 - 1316 | - JIN, W. ET AL., TRENDS ENDOCRINOL. METAB., (2002), vol. 13, no. 4, pages 174 - 178 | - WONG, H. ET AL., J. LIPID RES., (2002), vol. 43, pages 993 - 999 | - HIRATA, K. ET AL., J. BIOL. CHEM., (1999), vol. 274, no. 20, pages 14170 - 14175 | - JAYE, M. ET AL., NAT. GENET., (1999), vol. 21, pages 424 - 428 | - MCCOY, M.G., J. LIPID RES., (2002), vol. 43, pages 921 - 929 | - WIDDER, K. ET AL.,, Methods in Enzymology, ACADEMIC PRESS, (1985), vol. 112, pages 309 - 396 | - "Design and Application of Prodrugs", BUNDGAARD, H. ET AL., A Textbook of Drug Design and Development, HARWOOD ACADEMIC PUBLISHERS, (1991), pages 113 - 191 | - BUNDGAARD, H., ADV. DRUG DELIV. REV., (1992), vol. 8, pages 1 - 38 | - BUNDGAARD, H. ET AL., I PHARM. SCI., (1988), vol. 77, page 285 | - KAKEYA, N. ET AL., CHEM. PHARM. BULL., (1984), vol. 32, page 692 | - "Prodrugs and Targeted Delivery", Methods and Principles in Medicinal Chemistry, WILEY-VCH, (2011), vol. 47 | - FOLKMAN, J. ET AL., SCIENCE, (1987), vol. 235, pages 442 - 447 | - YANAGISAWA, M. ET AL., NATURE, (1988), vol. 332, no. 6163, pages 411 - 415 | - FOLKMAN, J. ET AL., J. BIOL. CHEM., (1992), vol. 267, no. 16, pages 10931 - 10934 | - JANSSENS, S.P. ET AL., J. BIOL. CHEM., (1992), vol. 267, no. 21, pages 14519 - 14522 | - LAMAS, S. ET AL., PROC. NATL. ACAD. SCI. U.S.A., (1992), vol. 89, no. 14, pages 6348 - 6352 | - LUSCHER, T.F. ET AL., HYPERTENSION, (1992), vol. 19, no. 2, pages 117 - 130 | - WILLIAMS ET AL., AM. REV. RESPIR. DIS., (1992), vol. 146, pages S45 - S50 | - BEVILACQUA, M.P. ET AL., J. CLIN. INVEST., (1993), vol. 91, no. 2, pages 379 - 387 | - CIRCULATION, (2012), vol. 125, pages E2 - E220 | - GORDON, D.J. ET AL., CIRCULATION, (1989), vol. 79, no. 1, pages 8 - 15 | - DELEMOS, A.S. ET AL., CIRCULATION, (2002), vol. 106, no. 11, pages 1321 - 1326 | - STRAUSS, J.G. ET AL., BIOCHEM. J., (2002), vol. 368, pages 69 - 79 |