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Extract from the Register of European Patents

EP About this file: EP2829281

EP2829281 - LPS VACCINE [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  22.11.2019
Database last updated on 24.07.2024
FormerThe patent has been granted
Status updated on  14.12.2018
FormerGrant of patent is intended
Status updated on  07.12.2018
FormerExamination is in progress
Status updated on  31.10.2018
FormerGrant of patent is intended
Status updated on  14.06.2018
FormerExamination is in progress
Status updated on  25.11.2016
Most recent event   Tooltip01.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 03.08.2022  [2022/31]
Applicant(s)For all designated states
KM Biologics Co., Ltd.
1-6-1 Okubo
Kita-ku
Kumamoto-shi
Kumamoto 860-8568 / JP
[2018/46]
Former [2015/05]For all designated states
The Chemo-Sero-Therapeutic Research Institute
1-6-1 Okubo, Kita-ku
Kumamoto-shi
Kumamoto 860-8568 / JP
Inventor(s)01 / SAKAMOTO, Ryuichi
c/o KM BIOLOGICS CO., LTD
1-6-1 Okubo, Kita-ku
Kumamoto-shi Kumamoto 860-8568 / JP
02 / SAKAGUCHI, Masashi
c/o KM BIOLOGICS CO., LTD
1314-1 Kyokushi-Kawabe
Kikuchi-shi Kumamoto 869-1298 / JP
 [2019/03]
Former [2015/05]01 / SAKAMOTO, Ryuichi
c/o THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE
1-6-1 Okubo, Kita-ku
Kunamoto-shi Kunamoto 860-8568 / JP
02 / SAKAGUCHI, Masashi
c/o THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE
KIKUCHI RESEARCH CENTER
1314-1 Kyokushi-Kawabe
Kikuchi-shi Kumamoto 869-1298 / JP
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[2019/03]
Former [2015/05]Vossius & Partner
Siebertstrasse 4
81675 München / DE
Application number, filing date13763687.419.02.2013
[2019/03]
WO2013JP54038
Priority number, dateJP2012006516222.03.2012         Original published format: JP 2012065162
[2015/05]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2013140919
Date:26.09.2013
Language:JA
[2013/39]
Type: A1 Application with search report 
No.:EP2829281
Date:28.01.2015
Language:EN
[2015/05]
Type: B1 Patent specification 
No.:EP2829281
Date:16.01.2019
Language:EN
[2019/03]
Search report(s)International search report - published on:JP26.09.2013
(Supplementary) European search report - dispatched on:EP13.10.2015
ClassificationIPC:A61K39/295, A61K39/00, A61K39/04, C12N7/00, A61K39/02, A61K39/112, A61K39/102
[2018/08]
CPC:
A61K39/0275 (EP,US); A61K39/02 (RU); A61K39/0208 (US);
A61K39/0241 (US); A61K39/025 (EP,US); A61K39/04 (US);
A61K39/102 (EP,US); A61K39/215 (US); A61K39/235 (US);
A61K39/295 (EP,US); A61P31/00 (EP); A61P31/04 (EP);
C12N7/00 (US); A61K2039/552 (EP,US); A61K2039/6037 (US);
A61K2039/70 (EP,US); A61K39/17 (US); C12N2710/10234 (US);
C12N2710/10271 (US); C12N2770/20034 (US); C12N2770/20071 (US);
Y02A50/30 (EP,US) (-)
Former IPC [2015/05]A61K39/02, A61K39/102, A61K39/108, A61K39/112, A61K39/12, A61K39/17, A61P31/00
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2015/05]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:LPS-IMPFSTOFF[2015/05]
English:LPS VACCINE[2015/05]
French:VACCIN CONTRE DES LIPOPOLYSACCHARIDES (LPS)[2015/05]
Entry into regional phase19.09.2014Translation filed 
19.09.2014National basic fee paid 
19.09.2014Search fee paid 
19.09.2014Designation fee(s) paid 
19.09.2014Examination fee paid 
Examination procedure09.09.2013Request for preliminary examination filed
International Preliminary Examining Authority: JP
19.09.2014Examination requested  [2015/05]
02.03.2016Amendment by applicant (claims and/or description)
26.07.2016Despatch of a communication from the examining division (Time limit: M04)
23.11.2016Reply to a communication from the examining division
11.01.2018Date of oral proceedings
22.05.2018Minutes of oral proceedings despatched
15.06.2018Communication of intention to grant the patent
23.10.2018Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
23.10.2018Fee for grant paid
23.10.2018Fee for publishing/printing paid
23.10.2018Receipt of the translation of the claim(s)
07.12.2018Information about intention to grant a patent
07.12.2018Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  26.07.2016
Opposition(s)17.10.2019No opposition filed within time limit [2019/52]
Fees paidRenewal fee
20.02.2015Renewal fee patent year 03
22.02.2016Renewal fee patent year 04
21.02.2017Renewal fee patent year 05
23.02.2018Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU19.02.2013
AL16.01.2019
AT16.01.2019
CY16.01.2019
CZ16.01.2019
DK16.01.2019
EE16.01.2019
FI16.01.2019
HR16.01.2019
IT16.01.2019
LT16.01.2019
LV16.01.2019
MC16.01.2019
MK16.01.2019
NL16.01.2019
PL16.01.2019
RO16.01.2019
RS16.01.2019
SE16.01.2019
SI16.01.2019
SK16.01.2019
SM16.01.2019
TR16.01.2019
IE19.02.2019
LU19.02.2019
MT19.02.2019
BE28.02.2019
CH28.02.2019
LI28.02.2019
BG16.04.2019
GB16.04.2019
NO16.04.2019
GR17.04.2019
IS16.05.2019
PT16.05.2019
[2022/31]
Former [2021/32]HU19.02.2013
AL16.01.2019
AT16.01.2019
CY16.01.2019
CZ16.01.2019
DK16.01.2019
EE16.01.2019
FI16.01.2019
HR16.01.2019
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TR16.01.2019
IE19.02.2019
LU19.02.2019
MT19.02.2019
BE28.02.2019
CH28.02.2019
LI28.02.2019
BG16.04.2019
GB16.04.2019
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PL16.01.2019
RO16.01.2019
RS16.01.2019
SE16.01.2019
SI16.01.2019
SK16.01.2019
SM16.01.2019
TR16.01.2019
IE19.02.2019
LU19.02.2019
MT19.02.2019
BE28.02.2019
CH28.02.2019
LI28.02.2019
BG16.04.2019
GB16.04.2019
NO16.04.2019
GR17.04.2019
IS16.05.2019
PT16.05.2019
Former [2020/29]AL16.01.2019
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SI16.01.2019
SK16.01.2019
SM16.01.2019
TR16.01.2019
IE19.02.2019
LU19.02.2019
MT19.02.2019
BE28.02.2019
CH28.02.2019
LI28.02.2019
BG16.04.2019
GB16.04.2019
NO16.04.2019
GR17.04.2019
IS16.05.2019
PT16.05.2019
Former [2020/17]AL16.01.2019
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PL16.01.2019
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RS16.01.2019
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SM16.01.2019
TR16.01.2019
IE19.02.2019
LU19.02.2019
BE28.02.2019
CH28.02.2019
LI28.02.2019
BG16.04.2019
GB16.04.2019
NO16.04.2019
GR17.04.2019
IS16.05.2019
PT16.05.2019
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EE16.01.2019
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MC16.01.2019
NL16.01.2019
PL16.01.2019
RO16.01.2019
RS16.01.2019
SE16.01.2019
SI16.01.2019
SK16.01.2019
SM16.01.2019
IE19.02.2019
LU19.02.2019
BE28.02.2019
CH28.02.2019
LI28.02.2019
BG16.04.2019
GB16.04.2019
NO16.04.2019
GR17.04.2019
IS16.05.2019
PT16.05.2019
Former [2020/09]AL16.01.2019
AT16.01.2019
CZ16.01.2019
DK16.01.2019
EE16.01.2019
FI16.01.2019
HR16.01.2019
IT16.01.2019
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LV16.01.2019
MC16.01.2019
NL16.01.2019
PL16.01.2019
RO16.01.2019
RS16.01.2019
SE16.01.2019
SK16.01.2019
SM16.01.2019
IE19.02.2019
LU19.02.2019
CH28.02.2019
LI28.02.2019
BG16.04.2019
NO16.04.2019
GR17.04.2019
IS16.05.2019
PT16.05.2019
Former [2020/04]AL16.01.2019
AT16.01.2019
CZ16.01.2019
DK16.01.2019
EE16.01.2019
FI16.01.2019
HR16.01.2019
IT16.01.2019
LT16.01.2019
LV16.01.2019
MC16.01.2019
NL16.01.2019
PL16.01.2019
RO16.01.2019
RS16.01.2019
SE16.01.2019
SK16.01.2019
SM16.01.2019
LU19.02.2019
CH28.02.2019
LI28.02.2019
BG16.04.2019
NO16.04.2019
GR17.04.2019
IS16.05.2019
PT16.05.2019
Former [2019/52]AL16.01.2019
AT16.01.2019
CZ16.01.2019
DK16.01.2019
EE16.01.2019
FI16.01.2019
HR16.01.2019
IT16.01.2019
LT16.01.2019
LV16.01.2019
MC16.01.2019
NL16.01.2019
PL16.01.2019
RO16.01.2019
RS16.01.2019
SE16.01.2019
SK16.01.2019
SM16.01.2019
LU19.02.2019
BG16.04.2019
NO16.04.2019
GR17.04.2019
IS16.05.2019
PT16.05.2019
Former [2019/49]AL16.01.2019
AT16.01.2019
CZ16.01.2019
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EE16.01.2019
FI16.01.2019
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IT16.01.2019
LT16.01.2019
LV16.01.2019
MC16.01.2019
NL16.01.2019
PL16.01.2019
RO16.01.2019
RS16.01.2019
SE16.01.2019
SK16.01.2019
LU19.02.2019
BG16.04.2019
NO16.04.2019
GR17.04.2019
IS16.05.2019
PT16.05.2019
Former [2019/48]AT16.01.2019
DK16.01.2019
FI16.01.2019
HR16.01.2019
IT16.01.2019
LT16.01.2019
LV16.01.2019
MC16.01.2019
NL16.01.2019
PL16.01.2019
RS16.01.2019
SE16.01.2019
LU19.02.2019
BG16.04.2019
NO16.04.2019
GR17.04.2019
IS16.05.2019
PT16.05.2019
Former [2019/47]AT16.01.2019
FI16.01.2019
HR16.01.2019
IT16.01.2019
LT16.01.2019
LV16.01.2019
MC16.01.2019
NL16.01.2019
PL16.01.2019
RS16.01.2019
SE16.01.2019
LU19.02.2019
BG16.04.2019
NO16.04.2019
GR17.04.2019
IS16.05.2019
PT16.05.2019
Former [2019/46]AT16.01.2019
FI16.01.2019
HR16.01.2019
IT16.01.2019
LT16.01.2019
LV16.01.2019
MC16.01.2019
NL16.01.2019
PL16.01.2019
RS16.01.2019
SE16.01.2019
BG16.04.2019
NO16.04.2019
GR17.04.2019
IS16.05.2019
PT16.05.2019
Former [2019/39]FI16.01.2019
HR16.01.2019
LT16.01.2019
LV16.01.2019
NL16.01.2019
PL16.01.2019
RS16.01.2019
SE16.01.2019
BG16.04.2019
NO16.04.2019
GR17.04.2019
IS16.05.2019
PT16.05.2019
Former [2019/38]FI16.01.2019
LT16.01.2019
NL16.01.2019
PL16.01.2019
SE16.01.2019
BG16.04.2019
NO16.04.2019
GR17.04.2019
PT16.05.2019
Former [2019/37]FI16.01.2019
LT16.01.2019
NL16.01.2019
PL16.01.2019
SE16.01.2019
NO16.04.2019
GR17.04.2019
PT16.05.2019
Former [2019/35]FI16.01.2019
LT16.01.2019
NL16.01.2019
PL16.01.2019
SE16.01.2019
NO16.04.2019
PT16.05.2019
Former [2019/34]FI16.01.2019
LT16.01.2019
NL16.01.2019
SE16.01.2019
NO16.04.2019
PT16.05.2019
Former [2019/33]FI16.01.2019
LT16.01.2019
NL16.01.2019
NO16.04.2019
PT16.05.2019
Former [2019/30]NL16.01.2019
Documents cited:Search[A]WO0004920  (MEGAN HEALTH INC [US], et al) [A] 1-7 * figure 3; example 1; claim 1 *;
 [A]US2005260225  (GOLDBERG JOANNA B [US], et al) [A] 1-15 * paragraphs [0002] , [0013] - [0015] - [0036] - [0039]; claims 1,12 *;
 [A]WO2005111196  (CA NAT RESEARCH COUNCIL [CA], et al) [A] 1-15 * page 12, lines 4-13 * * page 103, line 1 - page 110, line 14 ** claims 2,11,14 *;
 [A]WO2009046449  (UNIV ARIZONA [US], et al) [A] 1-15 * paragraphs [0052] - [0058] *;
 [XDI]  - WATSON D C ET AL, "Protection of Mice against Salmonella typhimunium with an 0-Specific Polysaccharide-Protein Conjugate Vaccine", INFECTION AND IMMUNITY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, (19920101), vol. 60, no. 11, ISSN 0019-9567, pages 4679 - 4686, XP008154178 [XD] 8-15 * abstract * * page 4679, column r, paragraph 3 * * page 4680, column l, paragraph 3 * * page 4680, column r, paragraph 3 * * page 4682, column r, paragraph 4 - page 4684, column l, paragraph 1 * * page 4684, column r, paragraph 4 * [I] 1-7
International search[Y]  - TIWARI,R.P. ET AL., "Immunobiology of lipopolysaccharide(LPS) and LPS-derived immunoconjugates vaccinate mice against Salmonella typhimurium", MICROBIOL. IMMUNOL., (1998), vol. 42, no. L, pages 1 - 5, XP055162292

DOI:   http://dx.doi.org/10.1111/j.1348-0421.1998.tb01962.x
 [Y]  - DEGUSHI,K. ET AL., "Efficacy of a novel trivalent inactivated vaccine against the shedding Salmonella in a chicken challenge model", AVIAN DISEASES, (2009), vol. 53, no. 2, pages 281 - 286, XP009174244

DOI:   http://dx.doi.org/10.1637/8516-110908-Reg.1
 [Y]  - REBERS,P.A. ET AL., "The effect of formalin- killing of Pasteurella multocida on the antigenicity and extractability of its lipopolysaccharide", CARBOHYDRATE RESEARCH, (1984), vol. 133, pages 83 - 94, XP026622253

DOI:   http://dx.doi.org/10.1016/0008-6215(84)85185-X
by applicantJP2001026602
 WO2004052394
 WO2010082020
    - INFECT. IMMUN, (1992), vol. 60, pages 4679 - 4686
    - VACCINE, (2010), vol. 28, pages 7551 - 7555
    - BULL. NATL. INST. HEALTH SCI., (2008), vol. 126, pages L9 - 33
    - AVIAN DISEASES, (2009), vol. 53, pages 281 - 286
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.