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Extract from the Register of European Patents

EP About this file: EP2912034

EP2912034 - 3,4-DISUBSTITUTED OXAZOLIDINONE DERIVATIVES AND THEIR USE AS INHIBITORS OF THE CALCIUM ACTIVATED POTASSIUM CHANNEL [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  06.04.2018
Database last updated on 28.09.2024
FormerThe patent has been granted
Status updated on  28.04.2017
FormerGrant of patent is intended
Status updated on  26.01.2017
FormerExamination is in progress
Status updated on  21.12.2016
Most recent event   Tooltip17.07.2020Lapse of the patent in a contracting state
New state(s): AL		published on 19.08.2020  [2020/34]
Applicant(s)For all designated states
F. Hoffmann-La Roche AG
Grenzacherstrasse 124
4070 Basel / CH
[2017/22]
Former [2015/36]For all designated states
F.Hoffmann-La Roche AG
Grenzacherstrasse 124
4070 Basel / CH
Inventor(s)01 / GREEN, Luke
Oetlingerstrasse 52
CH-4057 Basel / CH
02 / WANG, Haiyan
Brennerstrasse 54
CH-4123 Allschwil / CH
 [2015/36]
Representative(s)Schirlin, Julien
F. Hoffmann-La Roche AG
CLP - Patent Department
Grenzacherstrasse 124
4070 Basel / CH
[2015/36]
Application number, filing date13783333.125.10.2013
[2015/36]
WO2013EP72361
Priority number, dateEP2012019031929.10.2012         Original published format: EP 12190319
[2015/36]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2014067861
Date:08.05.2014
Language:EN
[2014/19]
Type: A1 Application with search report 
No.:EP2912034
Date:02.09.2015
Language:EN
The application published by WIPO in one of the EPO official languages on 08.05.2014 takes the place of the publication of the European patent application.
[2015/36]
Type: B1 Patent specification 
No.:EP2912034
Date:31.05.2017
Language:EN
[2017/22]
Search report(s)International search report - published on:EP08.05.2014
ClassificationIPC:C07D413/04, C07D413/06, C07D263/20, C07D263/32, A61K31/421, A61K31/422, A61P7/10, A61P9/10, A61P11/06, A61P13/12, A61P19/02, A61P29/00, A61P35/00
[2015/36]
CPC:
C07D263/20 (EP,CN,US); C07D413/04 (EP,CN,US); A61P1/04 (EP);
A61P11/06 (EP); A61P13/12 (EP); A61P19/02 (EP);
A61P25/00 (EP); A61P29/00 (EP); A61P35/00 (EP);
A61P35/02 (EP); A61P37/06 (EP); A61P7/10 (EP);
A61P9/10 (EP); C07D263/32 (EP,CN,US); C07D413/06 (EP,CN,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2015/36]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:3,4-DISUBSTITUIERTE OXAZOLIDINONDERIVATE UND IHRE VERWENDUNG ALS INHIBITOREN DES CALCIUM AKTIVIERTEN KALIUMKANALS[2017/07]
English:3,4-DISUBSTITUTED OXAZOLIDINONE DERIVATIVES AND THEIR USE AS INHIBITORS OF THE CALCIUM ACTIVATED POTASSIUM CHANNEL[2015/36]
French:DÉRIVÉS D'OXAZOLIDINONE 3,4-DISUBSTITUÉS ET LEUR UTILISATION EN TANT QU'INBITEURS DU CANAL DE POTASSIUM ACTIVÉ PAR LE CALCIUM[2017/07]
Former [2015/36]3,4-DISUBSTITUIERTE OXAZOLIDINONDERIVATE UND DEREN VERWENDUNG ALS INHIBITOREN DES CALCIUMAKTIVIERTEN KALIUMKANALKANALS
Former [2015/36]DÉRIVÉS D'OXAZOLIDINONE 3,4-DISUBSTITUÉE ET LEUR UTILISATION COMME INHIBITEURS DES CANAUX POTASSIQUES ACTIVÉS PAR LE CALCIUM
Entry into regional phase29.05.2015National basic fee paid 
29.05.2015Designation fee(s) paid 
29.05.2015Examination fee paid 
Examination procedure29.05.2015Examination requested  [2015/36]
06.01.2016Amendment by applicant (claims and/or description)
23.06.2016Despatch of a communication from the examining division (Time limit: M06)
15.12.2016Reply to a communication from the examining division
27.01.2017Communication of intention to grant the patent
19.04.2017Fee for grant paid
19.04.2017Fee for publishing/printing paid
19.04.2017Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  23.06.2016
Opposition(s)01.03.2018No opposition filed within time limit [2018/19]
Fees paidRenewal fee
07.10.2015Renewal fee patent year 03
07.10.2016Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU25.10.2013
AL31.05.2017
AT31.05.2017
CY31.05.2017
CZ31.05.2017
DK31.05.2017
EE31.05.2017
ES31.05.2017
FI31.05.2017
HR31.05.2017
IT31.05.2017
LT31.05.2017
LV31.05.2017
MC31.05.2017
MK31.05.2017
NL31.05.2017
PL31.05.2017
PT31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SI31.05.2017
SK31.05.2017
SM31.05.2017
TR31.05.2017
BG31.08.2017
NO31.08.2017
GR01.09.2017
IS30.09.2017
IE25.10.2017
LU25.10.2017
MT25.10.2017
BE31.10.2017
[2020/34]
Former [2020/28]HU25.10.2013
AT31.05.2017
CY31.05.2017
CZ31.05.2017
DK31.05.2017
EE31.05.2017
ES31.05.2017
FI31.05.2017
HR31.05.2017
IT31.05.2017
LT31.05.2017
LV31.05.2017
MC31.05.2017
MK31.05.2017
NL31.05.2017
PL31.05.2017
PT31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SI31.05.2017
SK31.05.2017
SM31.05.2017
TR31.05.2017
BG31.08.2017
NO31.08.2017
GR01.09.2017
IS30.09.2017
IE25.10.2017
LU25.10.2017
MT25.10.2017
BE31.10.2017
Former [2020/15]HU25.10.2013
AT31.05.2017
CY31.05.2017
CZ31.05.2017
DK31.05.2017
EE31.05.2017
ES31.05.2017
FI31.05.2017
HR31.05.2017
IT31.05.2017
LT31.05.2017
LV31.05.2017
MC31.05.2017
MK31.05.2017
NL31.05.2017
PL31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SI31.05.2017
SK31.05.2017
SM31.05.2017
TR31.05.2017
BG31.08.2017
NO31.08.2017
GR01.09.2017
IS30.09.2017
IE25.10.2017
LU25.10.2017
MT25.10.2017
BE31.10.2017
Former [2019/51]HU25.10.2013
AT31.05.2017
CY31.05.2017
CZ31.05.2017
DK31.05.2017
EE31.05.2017
ES31.05.2017
FI31.05.2017
HR31.05.2017
IT31.05.2017
LT31.05.2017
LV31.05.2017
MC31.05.2017
MK31.05.2017
NL31.05.2017
PL31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SI31.05.2017
SK31.05.2017
SM31.05.2017
BG31.08.2017
NO31.08.2017
GR01.09.2017
IS30.09.2017
IE25.10.2017
LU25.10.2017
MT25.10.2017
BE31.10.2017
Former [2019/47]HU25.10.2013
AT31.05.2017
CY31.05.2017
CZ31.05.2017
DK31.05.2017
EE31.05.2017
ES31.05.2017
FI31.05.2017
HR31.05.2017
IT31.05.2017
LT31.05.2017
LV31.05.2017
MC31.05.2017
NL31.05.2017
PL31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SI31.05.2017
SK31.05.2017
SM31.05.2017
BG31.08.2017
NO31.08.2017
GR01.09.2017
IS30.09.2017
IE25.10.2017
LU25.10.2017
MT25.10.2017
BE31.10.2017
Former [2019/31]HU25.10.2013
AT31.05.2017
CZ31.05.2017
DK31.05.2017
EE31.05.2017
ES31.05.2017
FI31.05.2017
HR31.05.2017
IT31.05.2017
LT31.05.2017
LV31.05.2017
MC31.05.2017
NL31.05.2017
PL31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SI31.05.2017
SK31.05.2017
SM31.05.2017
BG31.08.2017
NO31.08.2017
GR01.09.2017
IS30.09.2017
IE25.10.2017
LU25.10.2017
MT25.10.2017
BE31.10.2017
Former [2018/45]AT31.05.2017
CZ31.05.2017
DK31.05.2017
EE31.05.2017
ES31.05.2017
FI31.05.2017
HR31.05.2017
IT31.05.2017
LT31.05.2017
LV31.05.2017
MC31.05.2017
NL31.05.2017
PL31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SI31.05.2017
SK31.05.2017
SM31.05.2017
BG31.08.2017
NO31.08.2017
GR01.09.2017
IS30.09.2017
IE25.10.2017
LU25.10.2017
MT25.10.2017
BE31.10.2017
Former [2018/43]AT31.05.2017
CZ31.05.2017
DK31.05.2017
EE31.05.2017
ES31.05.2017
FI31.05.2017
HR31.05.2017
IT31.05.2017
LT31.05.2017
LV31.05.2017
MC31.05.2017
NL31.05.2017
PL31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SI31.05.2017
SK31.05.2017
SM31.05.2017
BG31.08.2017
NO31.08.2017
GR01.09.2017
IS30.09.2017
LU25.10.2017
MT25.10.2017
BE31.10.2017
Former [2018/36]AT31.05.2017
CZ31.05.2017
DK31.05.2017
EE31.05.2017
ES31.05.2017
FI31.05.2017
HR31.05.2017
IT31.05.2017
LT31.05.2017
LV31.05.2017
MC31.05.2017
NL31.05.2017
PL31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SI31.05.2017
SK31.05.2017
SM31.05.2017
BG31.08.2017
NO31.08.2017
GR01.09.2017
IS30.09.2017
LU25.10.2017
BE31.10.2017
Former [2018/30]AT31.05.2017
CZ31.05.2017
DK31.05.2017
EE31.05.2017
ES31.05.2017
FI31.05.2017
HR31.05.2017
IT31.05.2017
LT31.05.2017
LV31.05.2017
MC31.05.2017
NL31.05.2017
PL31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SI31.05.2017
SK31.05.2017
SM31.05.2017
BG31.08.2017
NO31.08.2017
GR01.09.2017
IS30.09.2017
Former [2018/25]AT31.05.2017
CZ31.05.2017
DK31.05.2017
EE31.05.2017
ES31.05.2017
FI31.05.2017
HR31.05.2017
IT31.05.2017
LT31.05.2017
LV31.05.2017
NL31.05.2017
PL31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SI31.05.2017
SK31.05.2017
SM31.05.2017
BG31.08.2017
NO31.08.2017
GR01.09.2017
IS30.09.2017
Former [2018/11]AT31.05.2017
CZ31.05.2017
DK31.05.2017
EE31.05.2017
ES31.05.2017
FI31.05.2017
HR31.05.2017
IT31.05.2017
LT31.05.2017
LV31.05.2017
NL31.05.2017
PL31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SK31.05.2017
SM31.05.2017
BG31.08.2017
NO31.08.2017
GR01.09.2017
IS30.09.2017
Former [2018/10]AT31.05.2017
CZ31.05.2017
DK31.05.2017
EE31.05.2017
ES31.05.2017
FI31.05.2017
HR31.05.2017
LT31.05.2017
LV31.05.2017
NL31.05.2017
RO31.05.2017
RS31.05.2017
SE31.05.2017
SK31.05.2017
BG31.08.2017
NO31.08.2017
GR01.09.2017
IS30.09.2017
Former [2018/09]AT31.05.2017
DK31.05.2017
EE31.05.2017
ES31.05.2017
FI31.05.2017
HR31.05.2017
LT31.05.2017
LV31.05.2017
NL31.05.2017
RS31.05.2017
SE31.05.2017
BG31.08.2017
NO31.08.2017
GR01.09.2017
IS30.09.2017
Former [2017/52]AT31.05.2017
ES31.05.2017
FI31.05.2017
HR31.05.2017
LT31.05.2017
LV31.05.2017
NL31.05.2017
RS31.05.2017
SE31.05.2017
BG31.08.2017
NO31.08.2017
GR01.09.2017
IS30.09.2017
Former [2017/50]AT31.05.2017
ES31.05.2017
FI31.05.2017
HR31.05.2017
LT31.05.2017
LV31.05.2017
RS31.05.2017
SE31.05.2017
BG31.08.2017
NO31.08.2017
GR01.09.2017
IS30.09.2017
Former [2017/49]AT31.05.2017
ES31.05.2017
FI31.05.2017
HR31.05.2017
LT31.05.2017
NO31.08.2017
GR01.09.2017
IS30.09.2017
Cited inInternational searchWO9731892  [ ] (SANKYO CO [JP], et al);
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 [X]EP1254895  (EISAI CO LTD [JP]) [X] 1-16 * page 79, line 46 - line 49 *;
 [X]WO2007109098  (AZEVAN PHARMACEUTICALS INC [US], et al) [X] 1-20 * page 35, lines 3-10 and the 2-oxo-imidazolidine compounds of the tables wherein R10 represents an alkyl or a phenyl * * page 36, the 2-oxo-imidazolidine compound of the second table wherein R10 represents a phenyl * * page 48 - page 49; examples 1, 2 *;
 [X]WO2010123997  (ACHAOGEN INC [US], et al) [X] 1-16 * pages 51-52; step 2 of example 5 *;
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DOI:   http://dx.doi.org/10.2174/157017810791514814
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DOI:   http://dx.doi.org/10.1248/cpb.33.84
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