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Extract from the Register of European Patents

EP About this file: EP2917233

EP2917233 - ALBUMIN VARIANTS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  27.11.2020
Database last updated on 14.06.2024
FormerGrant of patent is intended
Status updated on  25.02.2020
FormerExamination is in progress
Status updated on  07.02.2020
FormerGrant of patent is intended
Status updated on  18.06.2019
FormerExamination is in progress
Status updated on  09.12.2016
Most recent event   Tooltip27.11.2020Application deemed to be withdrawnpublished on 30.12.2020  [2020/53]
Applicant(s)For all designated states
Albumedix Ltd
Castle Court, 59 Castle Boulevard
Nottingham NG7 1FD / GB
[2018/31]
Former [2016/33]For all designated states
Albumedix A/S
Lottenborgvej 26
2800 Kgs. Lyngby / DK
Former [2015/38]For all designated states
Novozymes Biopharma DK A/S
Krogshoejvej 36
2880 Bagsvaerd / DK
Inventor(s)01 / CAMERON, Jason
24 Lees Road
Mapperley
Nottingham Nottinghamshire NG3 6HB / GB
02 / DELAHAY, Karen
18 Belvoir Crescent
Langar
Nottingham Nottinghamshire NG13 9HU / GB
03 / NIELSEN, Jens Erik
Hoejgaardsvej 15B
3520 Farum / DK
04 / PLUMRIDGE, Andrew
103 Malthouse Road
Ilkeston Derbyshire DE7 4PX / GB
05 / ANDERSEN, Jan Terje
Hallagerbakken 66F
1256 Oslo / NO
[N/P]
Former [2015/38]01 / CAMERON, Jason
24 Lees Road
Mapperley
Nottingham Nottinghamshire NG3 6HB / GB
02 / DELAHAY, Karen
18 Belvoir Crescent
Langar
Nottingham Nottinghamshire NG13 9HU / GB
03 / NIELSEN, Jens Erik
Hoejgaardsvej 15B
3520 Farum / DK
04 / PLUMRIDGE, Andrew
103 Malthouse Road
Ilkeston Derbyshire DE7 4PX / GB
05 / ANDERSEN, Jan Terje
Professor Lochmannsgate 6A
0559 Oslo / NO
Representative(s)Williams, Rachel Clare
Albumedix Ltd
Mabel Street
Nottingham NG2 3ED / GB
[N/P]
Former [2015/38]Williams, Rachel Clare
Novozymes Biopharma UK Limited
Castle Court
59 Castle Boulevard
Nottingham
Nottinghamshire NG7 1FD / GB
Application number, filing date13789000.008.11.2013
[2015/38]
WO2013EP73426
Priority number, dateEP2012019185608.11.2012         Original published format: EP 12191856
[2015/38]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2014072481
Date:15.05.2014
Language:EN
[2014/20]
Type: A1 Application with search report 
No.:EP2917233
Date:16.09.2015
Language:EN
The application published by WIPO in one of the EPO official languages on 15.05.2014 takes the place of the publication of the European patent application.
[2015/38]
Search report(s)International search report - published on:EP15.05.2014
(Supplementary) European search report - dispatched on:EP08.08.2016
ClassificationIPC:C07K14/765, A61K38/38, C12N15/62, // A61K39/385
[2019/21]
CPC:
C07K14/765 (EP,GB,RU,US); A61K38/00 (RU); A61K38/385 (EP,GB,US);
A61K39/385 (EP,US); A61P43/00 (EP); C07K2319/00 (EP,US);
C07K2319/31 (EP,US) (-)
Former IPC [2015/38]C07K14/765, A61K38/38, C12N15/62
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2015/38]
TitleGerman:ALBUMINVARIANTEN[2015/38]
English:ALBUMIN VARIANTS[2015/38]
French:VARIANTS D'ALBUMINE[2015/38]
Entry into regional phase08.06.2015National basic fee paid 
08.06.2015Designation fee(s) paid 
08.06.2015Examination fee paid 
Examination procedure08.06.2015Examination requested  [2015/38]
24.12.2015Amendment by applicant (claims and/or description)
08.08.2016Despatch of a communication from the examining division to which search results under Rule 164(2) EPC are annexed (Time limit: M06) [2016/36]
08.08.2016Despatch of a communication from the examining division (Time limit: M06)
11.05.2017Reply to a communication from the examining division
22.09.2017Despatch of a communication from the examining division (Time limit: M06)
03.04.2018Reply to a communication from the examining division
23.05.2018Despatch of a communication from the examining division (Time limit: M06)
22.02.2019Reply to a communication from the examining division
19.06.2019Communication of intention to grant the patent
29.10.2019Fee for grant paid
29.10.2019Fee for publishing/printing paid
04.02.2020Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
26.02.2020Communication of intention to grant the patent
08.07.2020Application deemed to be withdrawn, date of legal effect  [2020/53]
13.08.2020Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time  [2020/53]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  08.08.2016
Request for further processing for:The application is deemed to be withdrawn due to failure to fulfill actions required for granting the patent
04.02.2020Request for further processing filed
04.02.2020Full payment received (date of receipt of payment)
Request granted
11.02.2020Decision despatched
The application is deemed to be withdrawn due to failure to reply to the examination report
22.02.2019Request for further processing filed
22.02.2019Full payment received (date of receipt of payment)
Request granted
04.02.2019Decision despatched
The application is deemed to be withdrawn due to failure to reply to the examination report
11.05.2017Request for further processing filed
11.05.2017Full payment received (date of receipt of payment)
Request granted
18.09.2017Decision despatched
Fees paidRenewal fee
30.11.2015Renewal fee patent year 03
30.11.2016Renewal fee patent year 04
30.11.2017Renewal fee patent year 05
30.11.2018Renewal fee patent year 06
02.12.2019Renewal fee patent year 07
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[XDI]WO2011051489  (NOVOZYMES BIOPHARMA DK AS [DK], et al) [XD] 1-3,12,13,21-24,28,30-34,39-41,43-64 * the whole document * [I] 4-7,14-20,25-27,29,35-38,42;
 [XI]WO2011124718  (NOVOZYMES AS [DK], et al) [X] 1-3,12,13,21-24,28,30-34,39-41,43-64 * the whole document * * figure -; claim 13; tables 12a,12b * [I] 4-7,14-20,25-27,29,35-38,42;
 [XI]WO2012059486  (NOVOZYMES BIOPHARMA DK AS [DK], et al) [X] 1-3,12,13,21-24,28,30-34,39-41,43-64 * figures 1-2; example -; claim -; table 1 * * the whole document * [I] 4-7,14-20,25-27,29,35-38,42;
 [XDPI]WO2012150319  (NOVOZYMES BIOPHARMA DK AS [DK], et al) [XDP] 1-3,12,13,21-24,28,30-34,39-41,43-64 * the whole document * * figures 1-2, 22; tables 5, 7, 9, 16 * [I] 4-7,14-20,25-27,29,35-38,42;
 [AD]  - MASAKI OTAGIRI ET AL, "Pharmaceutically Important Pre- and Posttranslational Modifications on Human Serum Albumin", BIOLOGICAL & PHARMACEUTICAL BULLETIN, (20090101), vol. 32, no. 4, doi:10.1248/bpb.32.527, ISSN 0918-6158, pages 527 - 534, XP055054558 [AD] 1-7,12-64 * the whole document *

DOI:   http://dx.doi.org/10.1248/bpb.32.527
 [A]  - JAN TERJE ANDERSEN ET AL, "Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor", NATURE COMMUNICATIONS, (20120103), vol. 3, doi:10.1038/ncomms1607, page 610, XP055097625 [A] 1-7,12-64 * the whole document *

DOI:   http://dx.doi.org/10.1038/ncomms1607
 [A]  - Jan Terje Andersen ET AL, Nature Communications, (20120103), URL: http://www.nature.com/ncomms/journal/v3/n1/extref/ncomms1607-s1.pdf, (20140121), XP055097637 [A] 1-7,12-64
 [AD]  - CHAITY CHAUDHURY ET AL, "Albumin Binding to FcRn: Distinct from the FcRn-IgG Interaction", BIOCHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 45, no. 15, doi:10.1021/BI052628Y, ISSN 0006-2960, (20060418), pages 4983 - 4990, (20060322), XP002629973 [AD] 1-7,12-64 * the whole document *

DOI:   http://dx.doi.org/10.1021/bi052628y
 [AD]  - IWAO ET AL, "Changes of net charge and alpha-helical content affect the pharmacokinetic properties of human serum albumin", BIOCHIMICA ET BIOPHYSICA ACTA (BBA) - PROTEINS & PROTEOMICS, ELSEVIER, NETHERLANDS, (20070919), vol. 1774, no. 12, doi:10.1016/J.BBAPAP.2007.09.001, ISSN 1570-9639, pages 1582 - 1590, XP022385158 [AD] 1-7,12-64 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.bbapap.2007.09.001
 [AD]  - J. TERJE ANDERSEN ET AL, "Cross-species Binding Analyses of Mouse and Human Neonatal Fc Receptor Show Dramatic Differences in Immunoglobulin G and Albumin Binding", JOURNAL OF BIOLOGICAL CHEMISTRY, (20100212), vol. 285, no. 7, doi:10.1074/jbc.M109.081828, ISSN 0021-9258, pages 4826 - 4836, XP055022597 [AD] 1-7,12-64 * the whole document *

DOI:   http://dx.doi.org/10.1074/jbc.M109.081828
 [ADP]  - MICHAEL M. SCHMIDT ET AL, "Crystal Structure of an HSA/FcRn Complex Reveals Recycling by Competitive Mimicry of HSA Ligands at a pH-Dependent Hydrophobic Interface", STRUCTURE, (20131010), vol. 21, no. 11, doi:10.1016/j.str.2013.08.022, ISSN 0969-2126, pages 1966 - 1978, XP055097728 [ADP] 1-7,12-64 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.str.2013.08.022
 [ADP]  - Michael M Schmidt ET AL, "Supplemental Information to: Crystal Structure of an HSA/FcRn Complex Reveals Recycling by Competitive Mimicry of HSA Ligands at a pH-Dependent Hydrophobic Interface", Structure, Volume 21, 1966-1978, (20131010), URL: http://dx.doi.org/10.1016/j.str.2013.08.022, (20140122), XP055097774 [ADP] 1-7,12-64 * the whole document *
ExaminationWO2011051489
 WO2011124718
 WO2012059486
 WO2012150319
    - MASAKI OTAGIRI ET AL, "Pharmaceutically Important Pre- and Posttranslational Modifications on Human Serum Albumin", BIOLOGICAL & PHARMACEUTICAL BULLETIN, (20090101), vol. 32, no. 4, doi:10.1248/bpb.32.527, ISSN 0918-6158, pages 527 - 534, XP055054558

DOI:   http://dx.doi.org/10.1248/bpb.32.527
    - JAN TERJE ANDERSEN ET AL, "Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor", NATURE COMMUNICATIONS, (20120103), vol. 3, doi:10.1038/ncomms1607, page 610, XP055097625

DOI:   http://dx.doi.org/10.1038/ncomms1607
    - Jan Terje Andersen ET AL, Nature Communications, (20120103), URL: http://www.nature.com/ncomms/journal/v3/n1/pdf/ncomms1607.pdf, (20160712), XP055097637
    - CHAITY CHAUDHURY ET AL, "Albumin Binding to FcRn: Distinct from the FcRn-IgG Interaction", BIOCHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 45, no. 15, doi:10.1021/BI052628Y, ISSN 0006-2960, (20060418), pages 4983 - 4990, (20060322), XP002629973

DOI:   http://dx.doi.org/10.1021/bi052628y
    - IWAO ET AL, "Changes of net charge and alpha-helical content affect the pharmacokinetic properties of human serum albumin", BIOCHIMICA ET BIOPHYSICA ACTA (BBA) - PROTEINS & PROTEOMICS, ELSEVIER, NETHERLANDS, (20071201), vol. 1774, no. 12, doi:10.1016/J.BBAPAP.2007.09.001, ISSN 1570-9639, pages 1582 - 1590, XP022385158

DOI:   http://dx.doi.org/10.1016/j.bbapap.2007.09.001
    - J. TERJE ANDERSEN ET AL, "Cross-species Binding Analyses of Mouse and Human Neonatal Fc Receptor Show Dramatic Differences in Immunoglobulin G and Albumin Binding", JOURNAL OF BIOLOGICAL CHEMISTRY, (20100212), vol. 285, no. 7, doi:10.1074/jbc.M109.081828, ISSN 0021-9258, pages 4826 - 4836, XP055022597

DOI:   http://dx.doi.org/10.1074/jbc.M109.081828
    - MICHAEL M. SCHMIDT ET AL, "Crystal Structure of an HSA/FcRn Complex Reveals Recycling by Competitive Mimicry of HSA Ligands at a pH-Dependent Hydrophobic Interface", STRUCTURE, (20131101), vol. 21, no. 11, doi:10.1016/j.str.2013.08.022, ISSN 0969-2126, pages 1966 - 1978, XP055097728

DOI:   http://dx.doi.org/10.1016/j.str.2013.08.022
    - Michael M Schmidt ET AL, "Supplemental Information to: Crystal Structure of an HSA/FcRn Complex Reveals Recycling by Competitive Mimicry of HSA Ligands at a pH-Dependent Hydrophobic Interface", Structure, Volume 21, 1966-1978, (20131010), URL: http://www.sciencedirect.com/science/MiamiMultiMediaURL/1-s2.0-S0969212613003432/1-s2.0-S0969212613003432-mmc1.pdf/272027/html/S0969212613003432/ef71cb44f4aa0d03a06d22cf6ab10b87/mmc1.pdf, (20160712), XP055097774
    - "SubName: Full=Serum albumin {ECO:0000313|Ensembl:ENSMMUP00000005101};", UniProt, (20110727), Database accession no. F7HCH0, URL: EBI, XP002759777
    - R. A. GIBBS ET AL, "Evolutionary and Biomedical Insights from the Rhesus Macaque Genome", SCIENCE, (20070413), vol. 316, no. 5822, doi:10.1126/science.1139247, ISSN 0036-8075, pages 222 - 234, XP055019956

DOI:   http://dx.doi.org/10.1126/science.1139247
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.