EP2852689 - NANO46 GENES AND METHODS TO PREDICT BREAST CANCER OUTCOME [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 16.10.2020 Database last updated on 20.05.2024 | |
Former | The patent has been granted Status updated on 08.11.2019 | ||
Former | Grant of patent is intended Status updated on 02.07.2019 | ||
Former | Examination is in progress Status updated on 21.04.2017 | Most recent event Tooltip | 08.07.2022 | Lapse of the patent in a contracting state New state(s): MK | published on 10.08.2022 [2022/32] | Applicant(s) | For all designated states Nanostring Technologies, Inc. 530 Fairview Avenue North, Suite 2000 Seattle, WA 98109 / US | For all designated states The University of North Carolina at Chapel Hill 100 Europa Drive, Suite 430 Chapel Hill, NC 27517 / US | For all designated states University of Utah Research Foundation 615 Arapeen Drive, Suite 310 Salt Lake City, UT 84108 / US | For all designated states Washington University One Brookings Drive Saint Louis, MO 63130 / US | For all designated states British Columbia Cancer Agency Branch 675 West 10th Avenue Vancouver, British Columbia V5Z 1L3 / CA | [2019/50] |
Former [2015/14] | For all designated states Nanostring Technologies, Inc. 530 Fairview Avenue North, Suite 2000 Seattle, WA 98109 / US | ||
For all designated states The University of North Carolina at Chapel Hill 100 Europa Drive, Suite 430 Chapel Hill, NC 27517 / US | |||
For all designated states University of Utah Research Foundation 615 Arapeen Drive, Suite 310 Salt Lake City, UT 84108 / US | |||
For all designated states Washington University One Brookings Drive Saint Louis, MO 63130 / US | |||
For all designated states British Columbia Cancer Agency Branch 675 West 10th Avenue Vancouver, British Columbia V5Z 1L3 / CA | Inventor(s) | 01 /
FERREE, Sean M. 7018 3rd Avenue NW Seattle, WA 98117 / US | 02 /
STORHOFF, James Justin 6520 36th Avenue NW Seattle, WA 98117 / US | 03 /
PARKER, Joel S. 1113 Churchwood Drive Apex, NC 27502 / US | 04 /
PEROU, Charles M. 103 Oak Spring Court Carrboro, NC 27510 / US | 05 /
ELLIS, Matthew J. 226 Spencer Road St. Louis, MO 63119 / US | 06 /
BERNARD, Philip S. 1375 East Bryan Avenue Salt Lake City, UT 84105 / US | 07 /
NIELSEN, Torsten O. 4360 Canterbury Crescent North Vancouver, BC V7R 3N6 / CA | [2015/14] | Representative(s) | Cooley (UK) LLP 22 Bishopsgate London EC2N 4BQ / GB | [N/P] |
Former [2019/50] | Cooley (UK) LLP Dashwood 69 Old Broad Street London EC2M 1QS / GB | ||
Former [2015/14] | Jappy, John William Graham Gill Jennings & Every LLP The Broadgate Tower 20 Primrose Street London EC2A 2ES / GB | Application number, filing date | 13794236.3 | 22.05.2013 | [2019/50] | WO2013US42157 | Priority number, date | US201261650209P | 22.05.2012 Original published format: US 201261650209 P | US201361753673P | 17.01.2013 Original published format: US 201361753673 P | [2015/14] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO2013177245 | Date: | 28.11.2013 | Language: | EN | [2013/48] | Type: | A2 Application without search report | No.: | EP2852689 | Date: | 01.04.2015 | Language: | EN | The application published by WIPO in one of the EPO official languages on 28.11.2013 takes the place of the publication of the European patent application. | [2015/14] | Type: | B1 Patent specification | No.: | EP2852689 | Date: | 11.12.2019 | Language: | EN | [2019/50] | Search report(s) | International search report - published on: | US | 29.01.2015 | (Supplementary) European search report - dispatched on: | EP | 12.04.2016 | Classification | IPC: | C12Q1/68 | [2015/14] | CPC: |
C12Q1/6886 (EP,CN,US);
C12Q2600/118 (EP,CN,US);
C12Q2600/158 (EP,CN,US)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2015/14] | Extension states | BA | 26.11.2014 | ME | 26.11.2014 | Title | German: | NANO46-GENE UND VERFAHREN ZUR VORHERSAGE VON BRUSTKREBSERGEBNISSEN | [2015/14] | English: | NANO46 GENES AND METHODS TO PREDICT BREAST CANCER OUTCOME | [2015/14] | French: | GÈNES NANO-46 ET PROCÉDÉS DE PRÉDICTION DE L'ÉVOLUTION DU CANCER DU SEIN | [2015/14] | Entry into regional phase | 26.11.2014 | National basic fee paid | 26.11.2014 | Search fee paid | 26.11.2014 | Designation fee(s) paid | 26.11.2014 | Examination fee paid | Examination procedure | 26.11.2014 | Examination requested [2015/14] | 14.11.2016 | Amendment by applicant (claims and/or description) | 21.04.2017 | Despatch of a communication from the examining division (Time limit: M06) | 11.10.2017 | Reply to a communication from the examining division | 16.02.2018 | Despatch of a communication from the examining division (Time limit: M06) | 17.08.2018 | Reply to a communication from the examining division | 20.02.2019 | Despatch of a communication from the examining division (Time limit: M02) | 02.05.2019 | Reply to a communication from the examining division | 03.07.2019 | Communication of intention to grant the patent | 04.11.2019 | Fee for grant paid | 04.11.2019 | Fee for publishing/printing paid | 04.11.2019 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 21.04.2017 | Opposition(s) | 14.09.2020 | No opposition filed within time limit [2020/47] | Fees paid | Renewal fee | 27.05.2015 | Renewal fee patent year 03 | 27.05.2016 | Renewal fee patent year 04 | 30.05.2017 | Renewal fee patent year 05 | 29.05.2018 | Renewal fee patent year 06 | 28.05.2019 | Renewal fee patent year 07 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 22.05.2013 | AL | 11.12.2019 | AT | 11.12.2019 | CY | 11.12.2019 | CZ | 11.12.2019 | DK | 11.12.2019 | EE | 11.12.2019 | FI | 11.12.2019 | HR | 11.12.2019 | LT | 11.12.2019 | LV | 11.12.2019 | MC | 11.12.2019 | MK | 11.12.2019 | MT | 11.12.2019 | NL | 11.12.2019 | PL | 11.12.2019 | RO | 11.12.2019 | RS | 11.12.2019 | SE | 11.12.2019 | SI | 11.12.2019 | SK | 11.12.2019 | SM | 11.12.2019 | TR | 11.12.2019 | BG | 11.03.2020 | NO | 11.03.2020 | GR | 12.03.2020 | IS | 11.04.2020 | PT | 06.05.2020 | LU | 22.05.2020 | BE | 31.05.2020 | [2022/32] |
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PT | 06.05.2020 | ||
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PT | 06.05.2020 | ||
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Former [2020/21] | NO | 11.03.2020 | Documents cited: | Search | [I]EP1641810 (GENOMIC HEALTH [US]) [I] 1-15 * the whole document *; | [X]WO2008150512 (UNIV LOUISVILLE RES FOUND [US], et al) [X] 1-15 * the whole document *; | [I]WO2009108215 (AVIARADX INC [US], et al) [I] 1-15 * the whole document *; | [X]WO2009158143 (UNIV NORTH CAROLINA [US], et al) [X] 1-15 * the whole document *; | [I]WO2011120984 (SIVIDON DIAGNOSTICS GMBH [DE], et al) [I] 1-15 * the whole document *; | [X] - PARKER JOEL S ET AL, "Supervised risk predictor of breast cancer based on intrinsic subtypes", JOURNAL OF CLINICAL ONCOLOGY, AMERICAN SOCIETY OF CLINICAL ONCOLOGY, US, (20090310), vol. 27, no. 8, doi:10.1200/JCO.2008.18.1370, ISSN 0732-183X, pages 1160 - 1167, XP009124878 [X] 1-15 * the whole document * DOI: http://dx.doi.org/10.1200/JCO.2008.18.1370 | [I] - MULLINS M ET AL, "Agreement in breast cancer classification between microarray and quantitative reverse transcription PCR from fresh-frozen and formalin-fixed, paraffin-embedded tissues", CLINICAL CHEMISTRY, AMERICAN ASSOCIATION FOR CLINICAL CHEMISTRY, WASHINGTON, DC, vol. 53, no. 7, doi:10.1373/CLINCHEM.2006.083725, ISSN 0009-9147, (20070701), pages 1273 - 1279, (20070524), XP002553359 [I] 1-15 * the whole document * DOI: http://dx.doi.org/10.1373/clinchem.2006.083725 | [I] - PLUCIENNIK ELZBIETA ET AL, "Breast cancer relapse prediction based on multi-gene RT-PCR algorithm.", MEDICAL SCIENCE MONITOR : INTERNATIONAL MEDICAL JOURNAL OF EXPERIMENTAL AND CLINICAL RESEARCH MAR 2010, (201003), vol. 16, no. 3, ISSN 1643-3750, pages CR132 - CR136, XP002755989 [I] 1-15 * the whole document * | [I] - SORLIE T ET AL, "Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, NATIONAL ACADEMY OF SCIENCES, US, (20010911), vol. 98, no. 19, doi:10.1073/PNAS.191367098, ISSN 0027-8424, pages 10869 - 10874, XP002215483 [I] 1-15 * the whole document * DOI: http://dx.doi.org/10.1073/pnas.191367098 | [X] - "AFFYMETRIX GENECHIP HUMAN GENOME U133 ARRAY SET HG-U133A", GEO, (20020311), XP002506341 [X] 8-11 * the whole document * | International search | [Y]US2010015607 (GEISS GARY K [US], et al); | [X]US2011145176 (PEROU CHARLES M [US], et al); | [A] - VAN DE VIJVER, MJ ET AL., "A Gene - Expression Signature As A Predictor Of Survival In Breast Cancer.", THE NEW ENGLAND JOUMAL OF MEDICINE., (20021219), vol. 347, no. 25, pages 1999 - 2009, XP008032093 DOI: http://dx.doi.org/10.1056/NEJMoa021967 | by applicant | US5384261 | US5708153 | US5770358 | US5789162 | US5800992 | US5856174 | US5922591 | US6020135 | US6033860 | US6040138 | US6040193 | US6344316 | EP1641810 | WO2007061876 | WO2007076129 | WO2007076132 | US2008032293 | WO2008124847 | US2009299640 | WO2009158143 | US2010015607 | WO2010019826 | US2010047924 | US2010261026 | US8415102 | - PARKER JOEL S et al., "Supervised risk predictor of breast cancer based on intrinsic subtypes", J. of Clinincal Oncology, Americal Soc. of Clinical Oncology, (20190310), vol. 27, no. 8, doi:doi:10.1200/JCO.2008.18.1370, pages 1160 - 1167, XP009124878 DOI: http://dx.doi.org/10.1200/JCO.2008.18.1370 | - PEROU et al., Nature, (20000000), vol. 406, no. 6797, pages 747 - 52 | - SORLIE et al., PNAS, (20010000), vol. 98, no. 19, pages 10869 - 74 | - NIELSEN et al., Clin. Cancer Res., (20090000), vol. 16, no. 21, pages 5222 - 5232 | - JAY R. HARRIS et al., Diseases of the breast, Lippincott Williams & Wilkins, pages 458 - 472 | - NARASHIMAN; CHU, PNAS, (20020000), vol. 99, pages 6567 - 6572 | - WEIS et al., TIG, (19920000), vol. 8, pages 263 - 64 | - SCHENA et al., Science, (19950000), vol. 270, pages 467 - 70 | - GEISS et al., Nature Biotechnology, (20080000), vol. 26, no. 3, pages 317 - 325 | - QUACKENBUSH, Nat. Genet., (20020000), vol. 32, pages 496 - 501 | - BENITO et al., Bioinformatics, (20040000), vol. 20, no. 1, pages 105 - 114 | - ROUZIER et al., J Clin Oncol, (20050000), vol. 23, pages 8331 - 9 | - SPRUANCE et al., Antimicrob. Agents & Chemo, (20040000), vol. 48, pages 2787 - 92 |