EP2917186 - ALKYL AMIDE-SUBSTITUTED PYRIMIDINE COMPOUNDS USEFUL IN THE MODULATION OF IL-12, IL-23 AND/OR IFN [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 24.08.2018 Database last updated on 17.07.2024 | |
Former | The patent has been granted Status updated on 15.09.2017 | ||
Former | Grant of patent is intended Status updated on 25.05.2017 | ||
Former | Examination is in progress Status updated on 10.05.2017 | ||
Former | Grant of patent is intended Status updated on 23.01.2017 | Most recent event Tooltip | 17.07.2020 | Lapse of the patent in a contracting state New state(s): AL | published on 19.08.2020 [2020/34] | Applicant(s) | For all designated states Bristol-Myers Squibb Company Route 206 and Province Line Road Princeton, NJ 08543 / US | [2015/38] | Inventor(s) | 01 /
SANTELLA, Joseph B. c/o Bristol-Myers Squibb Company Route 206&Province Line Road Princeton, New Jersey 08543 / US | 02 /
MOSLIN, Ryan M. c/o Bristol-Myers Squibb Company Route 206&Province Line Road Princeton, New Jersey 08543 / US | 03 /
WEINSTEIN, David S. c/o Bristol-Myers Squibb Company Route 206&Province Line Road Princeton, New Jersey 08543 / US | 04 /
WROBLESKI, Stephen T. c/o Bristol-Myers Squibb Company Route 206&Province Line Road Princeton, New Jersey 08543 / US | 05 /
TOKARSKI, John S. c/o Bristol-Myers Squibb Company Route 206&Province Line Road Princeton, New Jersey 08543 / US | [2015/38] | Representative(s) | Reitstötter Kinzebach Patentanwälte Sternwartstraße 4 81679 München / DE | [N/P] |
Former [2015/38] | Reitstötter Kinzebach Patentanwälte Sternwartstrasse 4 81679 München / DE | Application number, filing date | 13795913.6 | 07.11.2013 | [2015/38] | WO2013US68866 | Priority number, date | US201261723827P | 08.11.2012 Original published format: US 201261723827 P | [2015/38] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2014074670 | Date: | 15.05.2014 | Language: | EN | [2014/20] | Type: | A1 Application with search report | No.: | EP2917186 | Date: | 16.09.2015 | Language: | EN | The application published by WIPO in one of the EPO official languages on 15.05.2014 takes the place of the publication of the European patent application. | [2015/38] | Type: | B1 Patent specification | No.: | EP2917186 | Date: | 18.10.2017 | Language: | EN | [2017/42] | Search report(s) | International search report - published on: | EP | 15.05.2014 | Classification | IPC: | C07D239/95, A61K31/513, A61P35/00, A61P37/00, A61P29/00 | [2015/38] | CPC: |
C07D239/48 (EP,US);
A61P29/00 (EP);
A61P35/00 (EP);
A61P37/00 (EP);
A61P37/06 (EP);
A61P43/00 (EP);
C07D239/95 (EP,US)
(-)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2015/38] | Extension states | BA | Not yet paid | ME | Not yet paid | Title | German: | ALKYLAMID-SUBSTITUIERTE PYRIMIDINVERBINDUNGEN ZUR VERWENDUNG BEI DER MODULATION ON IL-12, IL-23 UND/ODER IFN | [2015/38] | English: | ALKYL AMIDE-SUBSTITUTED PYRIMIDINE COMPOUNDS USEFUL IN THE MODULATION OF IL-12, IL-23 AND/OR IFN | [2015/38] | French: | COMPOSÉS DE PYRIMIDINE SUBSTITUÉS PAR ALKYLAMIDE UTILES DANS LA MODULATION D'IL-12, IL-23 ET/OU IFN | [2015/38] | Entry into regional phase | 03.06.2015 | National basic fee paid | 03.06.2015 | Designation fee(s) paid | 03.06.2015 | Examination fee paid | Examination procedure | 03.06.2015 | Examination requested [2015/38] | 08.02.2016 | Amendment by applicant (claims and/or description) | 08.07.2016 | Despatch of a communication from the examining division (Time limit: M04) | 13.10.2016 | Reply to a communication from the examining division | 24.01.2017 | Communication of intention to grant the patent | 04.05.2017 | Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO | 26.05.2017 | Communication of intention to grant the patent | 05.09.2017 | Fee for grant paid | 05.09.2017 | Fee for publishing/printing paid | 05.09.2017 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 08.07.2016 | Opposition(s) | 19.07.2018 | No opposition filed within time limit [2018/39] | Fees paid | Renewal fee | 10.11.2015 | Renewal fee patent year 03 | 10.11.2016 | Renewal fee patent year 04 |
Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 07.11.2013 | AL | 18.10.2017 | AT | 18.10.2017 | CY | 18.10.2017 | CZ | 18.10.2017 | DK | 18.10.2017 | EE | 18.10.2017 | FI | 18.10.2017 | HR | 18.10.2017 | LT | 18.10.2017 | LV | 18.10.2017 | MC | 18.10.2017 | MK | 18.10.2017 | NL | 18.10.2017 | PL | 18.10.2017 | PT | 18.10.2017 | RO | 18.10.2017 | RS | 18.10.2017 | SE | 18.10.2017 | SI | 18.10.2017 | SK | 18.10.2017 | SM | 18.10.2017 | TR | 18.10.2017 | IE | 07.11.2017 | LU | 07.11.2017 | MT | 07.11.2017 | BE | 30.11.2017 | CH | 30.11.2017 | LI | 30.11.2017 | BG | 18.01.2018 | NO | 18.01.2018 | GR | 19.01.2018 | IS | 18.02.2018 | [2020/34] |
Former [2020/28] | HU | 07.11.2013 | |
AT | 18.10.2017 | ||
CY | 18.10.2017 | ||
CZ | 18.10.2017 | ||
DK | 18.10.2017 | ||
EE | 18.10.2017 | ||
FI | 18.10.2017 | ||
HR | 18.10.2017 | ||
LT | 18.10.2017 | ||
LV | 18.10.2017 | ||
MC | 18.10.2017 | ||
MK | 18.10.2017 | ||
NL | 18.10.2017 | ||
PL | 18.10.2017 | ||
PT | 18.10.2017 | ||
RO | 18.10.2017 | ||
RS | 18.10.2017 | ||
SE | 18.10.2017 | ||
SI | 18.10.2017 | ||
SK | 18.10.2017 | ||
SM | 18.10.2017 | ||
TR | 18.10.2017 | ||
IE | 07.11.2017 | ||
LU | 07.11.2017 | ||
MT | 07.11.2017 | ||
BE | 30.11.2017 | ||
CH | 30.11.2017 | ||
LI | 30.11.2017 | ||
BG | 18.01.2018 | ||
NO | 18.01.2018 | ||
GR | 19.01.2018 | ||
IS | 18.02.2018 | ||
Former [2020/16] | HU | 07.11.2013 | |
AT | 18.10.2017 | ||
CY | 18.10.2017 | ||
CZ | 18.10.2017 | ||
DK | 18.10.2017 | ||
EE | 18.10.2017 | ||
FI | 18.10.2017 | ||
HR | 18.10.2017 | ||
LT | 18.10.2017 | ||
LV | 18.10.2017 | ||
MC | 18.10.2017 | ||
MK | 18.10.2017 | ||
NL | 18.10.2017 | ||
PL | 18.10.2017 | ||
RO | 18.10.2017 | ||
RS | 18.10.2017 | ||
SE | 18.10.2017 | ||
SI | 18.10.2017 | ||
SK | 18.10.2017 | ||
SM | 18.10.2017 | ||
TR | 18.10.2017 | ||
IE | 07.11.2017 | ||
LU | 07.11.2017 | ||
MT | 07.11.2017 | ||
BE | 30.11.2017 | ||
CH | 30.11.2017 | ||
LI | 30.11.2017 | ||
BG | 18.01.2018 | ||
NO | 18.01.2018 | ||
GR | 19.01.2018 | ||
IS | 18.02.2018 | ||
Former [2019/51] | HU | 07.11.2013 | |
AT | 18.10.2017 | ||
CY | 18.10.2017 | ||
CZ | 18.10.2017 | ||
DK | 18.10.2017 | ||
EE | 18.10.2017 | ||
FI | 18.10.2017 | ||
HR | 18.10.2017 | ||
LT | 18.10.2017 | ||
LV | 18.10.2017 | ||
MC | 18.10.2017 | ||
MK | 18.10.2017 | ||
NL | 18.10.2017 | ||
PL | 18.10.2017 | ||
RO | 18.10.2017 | ||
RS | 18.10.2017 | ||
SE | 18.10.2017 | ||
SI | 18.10.2017 | ||
SK | 18.10.2017 | ||
SM | 18.10.2017 | ||
IE | 07.11.2017 | ||
LU | 07.11.2017 | ||
MT | 07.11.2017 | ||
BE | 30.11.2017 | ||
CH | 30.11.2017 | ||
LI | 30.11.2017 | ||
BG | 18.01.2018 | ||
NO | 18.01.2018 | ||
GR | 19.01.2018 | ||
IS | 18.02.2018 | ||
Former [2019/47] | HU | 07.11.2013 | |
AT | 18.10.2017 | ||
CY | 18.10.2017 | ||
CZ | 18.10.2017 | ||
DK | 18.10.2017 | ||
EE | 18.10.2017 | ||
FI | 18.10.2017 | ||
HR | 18.10.2017 | ||
LT | 18.10.2017 | ||
LV | 18.10.2017 | ||
MC | 18.10.2017 | ||
NL | 18.10.2017 | ||
PL | 18.10.2017 | ||
RO | 18.10.2017 | ||
RS | 18.10.2017 | ||
SE | 18.10.2017 | ||
SI | 18.10.2017 | ||
SK | 18.10.2017 | ||
SM | 18.10.2017 | ||
IE | 07.11.2017 | ||
LU | 07.11.2017 | ||
MT | 07.11.2017 | ||
BE | 30.11.2017 | ||
CH | 30.11.2017 | ||
LI | 30.11.2017 | ||
BG | 18.01.2018 | ||
NO | 18.01.2018 | ||
GR | 19.01.2018 | ||
IS | 18.02.2018 | ||
Former [2019/31] | HU | 07.11.2013 | |
AT | 18.10.2017 | ||
CZ | 18.10.2017 | ||
DK | 18.10.2017 | ||
EE | 18.10.2017 | ||
FI | 18.10.2017 | ||
HR | 18.10.2017 | ||
LT | 18.10.2017 | ||
LV | 18.10.2017 | ||
MC | 18.10.2017 | ||
NL | 18.10.2017 | ||
PL | 18.10.2017 | ||
RO | 18.10.2017 | ||
RS | 18.10.2017 | ||
SE | 18.10.2017 | ||
SI | 18.10.2017 | ||
SK | 18.10.2017 | ||
SM | 18.10.2017 | ||
IE | 07.11.2017 | ||
LU | 07.11.2017 | ||
MT | 07.11.2017 | ||
BE | 30.11.2017 | ||
CH | 30.11.2017 | ||
LI | 30.11.2017 | ||
BG | 18.01.2018 | ||
NO | 18.01.2018 | ||
GR | 19.01.2018 | ||
IS | 18.02.2018 | ||
Former [2018/52] | AT | 18.10.2017 | |
CZ | 18.10.2017 | ||
DK | 18.10.2017 | ||
EE | 18.10.2017 | ||
FI | 18.10.2017 | ||
HR | 18.10.2017 | ||
LT | 18.10.2017 | ||
LV | 18.10.2017 | ||
MC | 18.10.2017 | ||
NL | 18.10.2017 | ||
PL | 18.10.2017 | ||
RO | 18.10.2017 | ||
RS | 18.10.2017 | ||
SE | 18.10.2017 | ||
SI | 18.10.2017 | ||
SK | 18.10.2017 | ||
SM | 18.10.2017 | ||
IE | 07.11.2017 | ||
LU | 07.11.2017 | ||
MT | 07.11.2017 | ||
BE | 30.11.2017 | ||
CH | 30.11.2017 | ||
LI | 30.11.2017 | ||
BG | 18.01.2018 | ||
NO | 18.01.2018 | ||
GR | 19.01.2018 | ||
IS | 18.02.2018 | ||
Former [2018/50] | AT | 18.10.2017 | |
CZ | 18.10.2017 | ||
DK | 18.10.2017 | ||
EE | 18.10.2017 | ||
FI | 18.10.2017 | ||
HR | 18.10.2017 | ||
LT | 18.10.2017 | ||
LV | 18.10.2017 | ||
MC | 18.10.2017 | ||
NL | 18.10.2017 | ||
PL | 18.10.2017 | ||
RO | 18.10.2017 | ||
RS | 18.10.2017 | ||
SE | 18.10.2017 | ||
SK | 18.10.2017 | ||
SM | 18.10.2017 | ||
IE | 07.11.2017 | ||
LU | 07.11.2017 | ||
MT | 07.11.2017 | ||
BE | 30.11.2017 | ||
CH | 30.11.2017 | ||
LI | 30.11.2017 | ||
BG | 18.01.2018 | ||
NO | 18.01.2018 | ||
GR | 19.01.2018 | ||
IS | 18.02.2018 | ||
Former [2018/45] | AT | 18.10.2017 | |
CZ | 18.10.2017 | ||
DK | 18.10.2017 | ||
EE | 18.10.2017 | ||
FI | 18.10.2017 | ||
HR | 18.10.2017 | ||
LT | 18.10.2017 | ||
LV | 18.10.2017 | ||
MC | 18.10.2017 | ||
NL | 18.10.2017 | ||
PL | 18.10.2017 | ||
RO | 18.10.2017 | ||
RS | 18.10.2017 | ||
SE | 18.10.2017 | ||
SK | 18.10.2017 | ||
SM | 18.10.2017 | ||
IE | 07.11.2017 | ||
LU | 07.11.2017 | ||
MT | 07.11.2017 | ||
CH | 30.11.2017 | ||
LI | 30.11.2017 | ||
BG | 18.01.2018 | ||
NO | 18.01.2018 | ||
GR | 19.01.2018 | ||
IS | 18.02.2018 | ||
Former [2018/43] | AT | 18.10.2017 | |
CZ | 18.10.2017 | ||
DK | 18.10.2017 | ||
EE | 18.10.2017 | ||
FI | 18.10.2017 | ||
HR | 18.10.2017 | ||
LT | 18.10.2017 | ||
LV | 18.10.2017 | ||
MC | 18.10.2017 | ||
NL | 18.10.2017 | ||
PL | 18.10.2017 | ||
RO | 18.10.2017 | ||
RS | 18.10.2017 | ||
SE | 18.10.2017 | ||
SK | 18.10.2017 | ||
SM | 18.10.2017 | ||
LU | 07.11.2017 | ||
MT | 07.11.2017 | ||
CH | 30.11.2017 | ||
LI | 30.11.2017 | ||
BG | 18.01.2018 | ||
NO | 18.01.2018 | ||
GR | 19.01.2018 | ||
IS | 18.02.2018 | ||
Former [2018/40] | AT | 18.10.2017 | |
CZ | 18.10.2017 | ||
DK | 18.10.2017 | ||
EE | 18.10.2017 | ||
FI | 18.10.2017 | ||
HR | 18.10.2017 | ||
LT | 18.10.2017 | ||
LV | 18.10.2017 | ||
MC | 18.10.2017 | ||
NL | 18.10.2017 | ||
PL | 18.10.2017 | ||
RO | 18.10.2017 | ||
RS | 18.10.2017 | ||
SE | 18.10.2017 | ||
SK | 18.10.2017 | ||
SM | 18.10.2017 | ||
LU | 07.11.2017 | ||
CH | 30.11.2017 | ||
LI | 30.11.2017 | ||
BG | 18.01.2018 | ||
NO | 18.01.2018 | ||
GR | 19.01.2018 | ||
IS | 18.02.2018 | ||
Former [2018/38] | AT | 18.10.2017 | |
CZ | 18.10.2017 | ||
DK | 18.10.2017 | ||
EE | 18.10.2017 | ||
FI | 18.10.2017 | ||
HR | 18.10.2017 | ||
LT | 18.10.2017 | ||
LV | 18.10.2017 | ||
MC | 18.10.2017 | ||
NL | 18.10.2017 | ||
PL | 18.10.2017 | ||
RS | 18.10.2017 | ||
SE | 18.10.2017 | ||
SK | 18.10.2017 | ||
SM | 18.10.2017 | ||
LU | 07.11.2017 | ||
CH | 30.11.2017 | ||
LI | 30.11.2017 | ||
BG | 18.01.2018 | ||
NO | 18.01.2018 | ||
GR | 19.01.2018 | ||
IS | 18.02.2018 | ||
Former [2018/37] | AT | 18.10.2017 | |
CZ | 18.10.2017 | ||
DK | 18.10.2017 | ||
EE | 18.10.2017 | ||
FI | 18.10.2017 | ||
HR | 18.10.2017 | ||
LT | 18.10.2017 | ||
LV | 18.10.2017 | ||
MC | 18.10.2017 | ||
NL | 18.10.2017 | ||
PL | 18.10.2017 | ||
RS | 18.10.2017 | ||
SE | 18.10.2017 | ||
SK | 18.10.2017 | ||
SM | 18.10.2017 | ||
CH | 30.11.2017 | ||
LI | 30.11.2017 | ||
BG | 18.01.2018 | ||
NO | 18.01.2018 | ||
GR | 19.01.2018 | ||
IS | 18.02.2018 | ||
Former [2018/36] | AT | 18.10.2017 | |
CZ | 18.10.2017 | ||
DK | 18.10.2017 | ||
EE | 18.10.2017 | ||
FI | 18.10.2017 | ||
HR | 18.10.2017 | ||
LT | 18.10.2017 | ||
LV | 18.10.2017 | ||
MC | 18.10.2017 | ||
NL | 18.10.2017 | ||
PL | 18.10.2017 | ||
RS | 18.10.2017 | ||
SE | 18.10.2017 | ||
SK | 18.10.2017 | ||
CH | 30.11.2017 | ||
LI | 30.11.2017 | ||
BG | 18.01.2018 | ||
NO | 18.01.2018 | ||
GR | 19.01.2018 | ||
IS | 18.02.2018 | ||
Former [2018/35] | AT | 18.10.2017 | |
CZ | 18.10.2017 | ||
DK | 18.10.2017 | ||
EE | 18.10.2017 | ||
FI | 18.10.2017 | ||
HR | 18.10.2017 | ||
LT | 18.10.2017 | ||
LV | 18.10.2017 | ||
MC | 18.10.2017 | ||
NL | 18.10.2017 | ||
RS | 18.10.2017 | ||
SE | 18.10.2017 | ||
SK | 18.10.2017 | ||
CH | 30.11.2017 | ||
LI | 30.11.2017 | ||
BG | 18.01.2018 | ||
NO | 18.01.2018 | ||
GR | 19.01.2018 | ||
IS | 18.02.2018 | ||
Former [2018/24] | AT | 18.10.2017 | |
FI | 18.10.2017 | ||
HR | 18.10.2017 | ||
LT | 18.10.2017 | ||
LV | 18.10.2017 | ||
NL | 18.10.2017 | ||
RS | 18.10.2017 | ||
SE | 18.10.2017 | ||
BG | 18.01.2018 | ||
NO | 18.01.2018 | ||
GR | 19.01.2018 | ||
IS | 18.02.2018 | ||
Former [2018/22] | FI | 18.10.2017 | |
LT | 18.10.2017 | ||
NL | 18.10.2017 | ||
NO | 18.01.2018 | ||
Former [2018/17] | NL | 18.10.2017 | Cited in | International search | [X]EP1518855 (YAMANOUCHI PHARMA CO LTD [JP]) [X] 1-3,5,7,8,13-15 * claims 1,7,14 * * page 62; compound 247 *; | [X]WO2006035069 (TIBOTEC PHARM LTD [IE], et al) [X] 1-5,7,13,14 * claims 1,11,12 * * pages 39,40; compounds 11,23,24 *; | [I]WO2010106097 (BOEHRINGER INGELHEIM INT [DE], et al) [I] 1-5,7,8,13-15* claims 1, 13,14 *; | [X]WO2011065800 (OSCOTEC INC [KR], et al) [X] 1-8,12-14 * claim 1 * * pages 19,21,22; compounds 179,206,212 *; | [X]WO2012145569 (SIGNAL PHARM LLC [US], et al) [X] 1-4,7,8,13-15 * page 258; compound 206 * * claims 1,54,56-59 *; | [X] - HISAMICHI H ET AL, "Corrigendum to ''Synthetic studies on novel Syk inhibitors. Part 1: Synthesis and structure-activity relationships of pyrimidine-5-carboxamide derivatives'' [Bioorg. Med. Chem. 13 (2005) 4936-4951]", BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON, GB, vol. 13, no. 22, ISSN 0968-0896, (20051115), pages 6277 - 6279, (20051115), XP027638222 [X] 1-4,7,8,13-15 * compound 14e * |