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Extract from the Register of European Patents

EP About this file: EP2935624

EP2935624 - A NOVEL LIGASE ACTIVITY [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  07.09.2018
Database last updated on 19.10.2024
FormerThe patent has been granted
Status updated on  29.09.2017
FormerGrant of patent is intended
Status updated on  18.05.2017
FormerExamination is in progress
Status updated on  25.01.2017
Most recent event   Tooltip17.07.2020Lapse of the patent in a contracting state
New state(s): AL		published on 19.08.2020  [2020/34]
Applicant(s)For all designated states
New England Biolabs, Inc.
240 County Road
Ipswich, MA 01938 / US
[2015/44]
Inventor(s)01 / LOHMAN, Gregory
9 Cleveland Street ¤1
Sommerville, MA 02143 / US
02 / EVANS, Thomas, C.
45 Fox Run Road
Topsfield, MA 01983 / US
03 / McREYNOLDS, Larry A.
25 Pickman Road
Beverly, MA 01915 / US
 [2017/44]
Former [2015/44]01 / LOHMAN, Gregory
255 Garden Street 16
Cambridge, MA 02138 / US
02 / EVANS, Thomas, C.
45 Fox Run Road
Topsfield, MA 01983 / US
03 / McREYNOLDS, Larry A.
25 Pickman Road
Beverly, MA 01915 / US
Representative(s)Griffin, Philippa Jane, et al
Mathys & Squire The Shard
32 London Bridge Street
London SE1 9SG / GB
[N/P]
Former [2015/44]Griffin, Philippa Jane, et al
Mathys & Squire LLP The Shard
32 London Bridge Street
London SE1 9SG / GB
Application number, filing date13822026.419.12.2013
[2015/44]
WO2013US76684
Priority number, dateUS201261745244P21.12.2012         Original published format: US 201261745244 P
US20131382948914.03.2013         Original published format: US201313829489
[2015/44]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2014100473
Date:26.06.2014
Language:EN
[2014/26]
Type: A1 Application with search report 
No.:EP2935624
Date:28.10.2015
Language:EN
The application published by WIPO in one of the EPO official languages on 26.06.2014 takes the place of the publication of the European patent application.
[2015/44]
Type: B1 Patent specification 
No.:EP2935624
Date:01.11.2017
Language:EN
[2017/44]
Search report(s)International search report - published on:EP26.06.2014
ClassificationIPC:C12Q1/68
[2015/44]
CPC:
C12Q1/6862 (EP,US); C12N9/93 (US); C12N9/00 (EP,US);
C12Q1/6853 (EP,US); C12Y605/01003 (EP,US); C12Q2521/501 (EP,US);
C12Q2561/125 (EP,US) (-)
C-Set:
C12Q1/6853, C12Q2521/501 (US,EP);
C12Q1/6862, C12Q2521/501, C12Q2561/125 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2015/44]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:NEUARTIGE LIGASEAKTIVITÄT[2015/44]
English:A NOVEL LIGASE ACTIVITY[2015/44]
French:NOUVELLE ACTIVITÉ DE LIGASE[2015/44]
Entry into regional phase07.07.2015National basic fee paid 
07.07.2015Designation fee(s) paid 
07.07.2015Examination fee paid 
Examination procedure07.07.2015Amendment by applicant (claims and/or description)
07.07.2015Examination requested  [2015/44]
29.06.2016Despatch of a communication from the examining division (Time limit: M04)
12.10.2016Reply to a communication from the examining division
16.01.2017Despatch of a communication from the examining division (Time limit: M04)
13.02.2017Reply to a communication from the examining division
19.05.2017Communication of intention to grant the patent
25.09.2017Fee for grant paid
25.09.2017Fee for publishing/printing paid
25.09.2017Receipt of the translation of the claim(s)
Divisional application(s)EP17193020.9  / EP3318645
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  29.06.2016
Opposition(s)02.08.2018No opposition filed within time limit [2018/41]
Fees paidRenewal fee
10.12.2015Renewal fee patent year 03
21.12.2016Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU19.12.2013
AL01.11.2017
AT01.11.2017
CY01.11.2017
CZ01.11.2017
DK01.11.2017
EE01.11.2017
ES01.11.2017
FI01.11.2017
GR01.11.2017
HR01.11.2017
IT01.11.2017
LT01.11.2017
LV01.11.2017
MC01.11.2017
MK01.11.2017
NL01.11.2017
PL01.11.2017
PT01.11.2017
RO01.11.2017
RS01.11.2017
SE01.11.2017
SI01.11.2017
SK01.11.2017
SM01.11.2017
TR01.11.2017
IE19.12.2017
LU19.12.2017
MT19.12.2017
BE31.12.2017
CH31.12.2017
LI31.12.2017
BG01.02.2018
NO01.02.2018
IS01.03.2018
[2020/34]
Former [2020/30]HU19.12.2013
AT01.11.2017
CY01.11.2017
CZ01.11.2017
DK01.11.2017
EE01.11.2017
ES01.11.2017
FI01.11.2017
GR01.11.2017
HR01.11.2017
IT01.11.2017
LT01.11.2017
LV01.11.2017
MC01.11.2017
MK01.11.2017
NL01.11.2017
PL01.11.2017
PT01.11.2017
RO01.11.2017
RS01.11.2017
SE01.11.2017
SI01.11.2017
SK01.11.2017
SM01.11.2017
TR01.11.2017
IE19.12.2017
LU19.12.2017
MT19.12.2017
BE31.12.2017
CH31.12.2017
LI31.12.2017
BG01.02.2018
NO01.02.2018
IS01.03.2018
Former [2020/28]HU19.12.2013
AT01.11.2017
CY01.11.2017
CZ01.11.2017
DK01.11.2017
EE01.11.2017
ES01.11.2017
FI01.11.2017
HR01.11.2017
IT01.11.2017
LT01.11.2017
LV01.11.2017
MC01.11.2017
MK01.11.2017
NL01.11.2017
PL01.11.2017
PT01.11.2017
RO01.11.2017
RS01.11.2017
SE01.11.2017
SI01.11.2017
SK01.11.2017
SM01.11.2017
TR01.11.2017
IE19.12.2017
LU19.12.2017
MT19.12.2017
BE31.12.2017
CH31.12.2017
LI31.12.2017
BG01.02.2018
NO01.02.2018
IS01.03.2018
Former [2020/16]HU19.12.2013
AT01.11.2017
CY01.11.2017
CZ01.11.2017
DK01.11.2017
EE01.11.2017
ES01.11.2017
FI01.11.2017
HR01.11.2017
IT01.11.2017
LT01.11.2017
LV01.11.2017
MC01.11.2017
MK01.11.2017
NL01.11.2017
PL01.11.2017
RO01.11.2017
RS01.11.2017
SE01.11.2017
SI01.11.2017
SK01.11.2017
SM01.11.2017
TR01.11.2017
IE19.12.2017
LU19.12.2017
MT19.12.2017
BE31.12.2017
CH31.12.2017
LI31.12.2017
BG01.02.2018
NO01.02.2018
IS01.03.2018
Former [2019/52]HU19.12.2013
AT01.11.2017
CY01.11.2017
CZ01.11.2017
DK01.11.2017
EE01.11.2017
ES01.11.2017
FI01.11.2017
HR01.11.2017
IT01.11.2017
LT01.11.2017
LV01.11.2017
MC01.11.2017
MK01.11.2017
NL01.11.2017
PL01.11.2017
RO01.11.2017
RS01.11.2017
SE01.11.2017
SI01.11.2017
SK01.11.2017
SM01.11.2017
IE19.12.2017
LU19.12.2017
MT19.12.2017
BE31.12.2017
CH31.12.2017
LI31.12.2017
BG01.02.2018
NO01.02.2018
IS01.03.2018
Former [2019/31]HU19.12.2013
AT01.11.2017
CY01.11.2017
CZ01.11.2017
DK01.11.2017
EE01.11.2017
ES01.11.2017
FI01.11.2017
HR01.11.2017
IT01.11.2017
LT01.11.2017
LV01.11.2017
MC01.11.2017
NL01.11.2017
PL01.11.2017
RO01.11.2017
RS01.11.2017
SE01.11.2017
SI01.11.2017
SK01.11.2017
SM01.11.2017
IE19.12.2017
LU19.12.2017
MT19.12.2017
BE31.12.2017
CH31.12.2017
LI31.12.2017
BG01.02.2018
NO01.02.2018
IS01.03.2018
Former [2019/30]AT01.11.2017
CY01.11.2017
CZ01.11.2017
DK01.11.2017
EE01.11.2017
ES01.11.2017
FI01.11.2017
HR01.11.2017
IT01.11.2017
LT01.11.2017
LV01.11.2017
MC01.11.2017
NL01.11.2017
PL01.11.2017
RO01.11.2017
RS01.11.2017
SE01.11.2017
SI01.11.2017
SK01.11.2017
SM01.11.2017
IE19.12.2017
LU19.12.2017
MT19.12.2017
BE31.12.2017
CH31.12.2017
LI31.12.2017
BG01.02.2018
NO01.02.2018
IS01.03.2018
Former [2018/52]AT01.11.2017
CY01.11.2017
CZ01.11.2017
DK01.11.2017
EE01.11.2017
ES01.11.2017
FI01.11.2017
HR01.11.2017
IT01.11.2017
LT01.11.2017
LV01.11.2017
NL01.11.2017
PL01.11.2017
RO01.11.2017
RS01.11.2017
SE01.11.2017
SI01.11.2017
SK01.11.2017
SM01.11.2017
IE19.12.2017
LU19.12.2017
MT19.12.2017
BE31.12.2017
CH31.12.2017
LI31.12.2017
BG01.02.2018
NO01.02.2018
IS01.03.2018
Former [2018/50]AT01.11.2017
CY01.11.2017
CZ01.11.2017
DK01.11.2017
EE01.11.2017
ES01.11.2017
FI01.11.2017
HR01.11.2017
IT01.11.2017
LT01.11.2017
LV01.11.2017
NL01.11.2017
PL01.11.2017
RO01.11.2017
RS01.11.2017
SE01.11.2017
SK01.11.2017
SM01.11.2017
IE19.12.2017
LU19.12.2017
MT19.12.2017
BE31.12.2017
BG01.02.2018
NO01.02.2018
IS01.03.2018
Former [2018/45]AT01.11.2017
CY01.11.2017
CZ01.11.2017
DK01.11.2017
EE01.11.2017
ES01.11.2017
FI01.11.2017
HR01.11.2017
IT01.11.2017
LT01.11.2017
LV01.11.2017
NL01.11.2017
PL01.11.2017
RO01.11.2017
RS01.11.2017
SE01.11.2017
SK01.11.2017
SM01.11.2017
IE19.12.2017
LU19.12.2017
MT19.12.2017
BG01.02.2018
NO01.02.2018
IS01.03.2018
Former [2018/43]AT01.11.2017
CY01.11.2017
CZ01.11.2017
DK01.11.2017
EE01.11.2017
ES01.11.2017
FI01.11.2017
HR01.11.2017
IT01.11.2017
LT01.11.2017
LV01.11.2017
NL01.11.2017
PL01.11.2017
RO01.11.2017
RS01.11.2017
SE01.11.2017
SK01.11.2017
SM01.11.2017
LU19.12.2017
MT19.12.2017
BG01.02.2018
NO01.02.2018
IS01.03.2018
Former [2018/40]AT01.11.2017
CY01.11.2017
CZ01.11.2017
DK01.11.2017
EE01.11.2017
ES01.11.2017
FI01.11.2017
HR01.11.2017
IT01.11.2017
LT01.11.2017
LV01.11.2017
NL01.11.2017
PL01.11.2017
RO01.11.2017
RS01.11.2017
SE01.11.2017
SK01.11.2017
SM01.11.2017
BG01.02.2018
NO01.02.2018
IS01.03.2018
Former [2018/39]AT01.11.2017
CY01.11.2017
CZ01.11.2017
DK01.11.2017
EE01.11.2017
ES01.11.2017
FI01.11.2017
HR01.11.2017
IT01.11.2017
LT01.11.2017
LV01.11.2017
NL01.11.2017
PL01.11.2017
RS01.11.2017
SE01.11.2017
SK01.11.2017
SM01.11.2017
BG01.02.2018
NO01.02.2018
IS01.03.2018
Former [2018/37]AT01.11.2017
CY01.11.2017
CZ01.11.2017
DK01.11.2017
EE01.11.2017
ES01.11.2017
FI01.11.2017
HR01.11.2017
LT01.11.2017
LV01.11.2017
NL01.11.2017
PL01.11.2017
RS01.11.2017
SE01.11.2017
SK01.11.2017
SM01.11.2017
BG01.02.2018
NO01.02.2018
IS01.03.2018
Former [2018/35]AT01.11.2017
CY01.11.2017
CZ01.11.2017
DK01.11.2017
EE01.11.2017
ES01.11.2017
FI01.11.2017
HR01.11.2017
LT01.11.2017
LV01.11.2017
NL01.11.2017
RS01.11.2017
SE01.11.2017
SK01.11.2017
BG01.02.2018
NO01.02.2018
IS01.03.2018
Former [2018/24]AT01.11.2017
ES01.11.2017
FI01.11.2017
HR01.11.2017
LT01.11.2017
LV01.11.2017
NL01.11.2017
RS01.11.2017
SE01.11.2017
BG01.02.2018
NO01.02.2018
IS01.03.2018
Former [2018/22]ES01.11.2017
FI01.11.2017
LT01.11.2017
NL01.11.2017
NO01.02.2018
Cited inInternational search[XI]WO0179420  (MOLECULAR STAGING INC [US]) [X] 1,3,7-10,13 * page 4, line 7 - line 12 * * page 28, line 17 - page 29, line 22; figure 1; claims 1-36 * [I] 2,4,13-17,19;
 [XI]  - C. K. Ho ET AL, "Characterization of an ATP-dependent DNA", Journal of Virology, (19970101), pages 1931 - 1937, URL: http://jvi.asm.org/content/71/3/1931.full.pdf, (20140306), XP055105858 [X] 1,3,5-7 * the whole document * [I] 4
 [XI]  - Mark Odell ET AL, "Footprinting of Chlorella Virus DNA Ligase Bound at a Nick in Duplex DNA", J. Biol. Chem., doi:10.1074/jbc.274.20.14032, (19990514), pages 14032 - 14039, URL: http://www.jbc.org/content/274/20/14032.full.pdf, (20140307), XP055106103 [X] 1,3,5-7 * the whole document * [I] 4

DOI:   http://dx.doi.org/10.1074/jbc.274.20.14032
 [XI]  - NILSSON M ET AL, "RNA-templated DNA ligation for transcript analysis", NUCLEIC ACIDS RESEARCH, OXFORD : OXFORD UNIV. PRESS, 1974-ANFANGS: LONDON : INFORMATION RETRIEVAL LTD, GB, (20010115), vol. 29, no. 2, doi:10.1093/NAR/29.2.578, ISSN 0305-1048, pages 578 - 581, XP002211638 [X] 1,5,7-12 * the whole document * [I] 2,4,16-18

DOI:   http://dx.doi.org/10.1093/nar/29.2.578
 [XI]  - BULLARD DESMOND R ET AL, "Direct comparison of nick-joining activity of the nucleic acid ligases from bacteriophage T4", BIOCHEMICAL JOURNAL, PUBLISHED BY PORTLAND PRESS ON BEHALF OF THE BIOCHEMICAL SOCIETY, (20060815), vol. 398, no. 1, doi:10.1042/BJ20060313, ISSN 0264-6021, pages 135 - 144, XP002467857 [X] 1,3,7-10,13 * abstract * [I] 2,4,13-17,19

DOI:   http://dx.doi.org/10.1042/BJ20060313
 [I]  - V SRISKANDA ET AL, "Specificity and fidelity of strand joining by Chlorella virus DNA ligase", NUCLEIC ACIDS RESEARCH, (19980801), vol. 26, no. 15, doi:10.1093/nar/26.15.3536, pages 3536 - 3541, XP055105855 [I] 1-19 * the whole document *

DOI:   http://dx.doi.org/10.1093/nar/26.15.3536
 [XP]  - G. J. S. LOHMAN ET AL, "Efficient DNA ligation in DNA-RNA hybrid helices by Chlorella virus DNA ligase", NUCLEIC ACIDS RESEARCH, (20131106), vol. 42, no. 3, doi:10.1093/nar/gkt1032, ISSN 0305-1048, pages 1831 - 1844, XP055105859 [XP] 1-19 * the whole document *

DOI:   http://dx.doi.org/10.1093/nar/gkt1032
by applicantUS554413
 US5429807
 US5599695
 US5871928
 US6368801
 US7361488
 US7888015
 US2011092375
 US2012244525
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.