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Extract from the Register of European Patents

EP About this file: EP2855523

EP2855523 - ANTIGEN BINDING PROTEINS THAT BIND DLL-4 [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  12.04.2019
Database last updated on 02.07.2024
FormerExamination is in progress
Status updated on  23.12.2016
Most recent event   Tooltip12.04.2019Application deemed to be withdrawnpublished on 15.05.2019  [2019/20]
Applicant(s)For all designated states
Sorrento Therapeutics, Inc.
6042 Cornerstone Ct. West
Suite B
San Diego, CA 92121 / US
[2015/15]
Inventor(s)01 / GROS, Edwige
967 Beryl Street
San Diego, CA 92109 / US
02 / ZHANG, Yanliang
10945 Corte Mejillones
San Diego, CA 92130 / US
03 / ZHOU, Heyue
10936 Via Banco
San Diego, CA 92126 / US
04 / GASTWIRT, Randy
4083 Sequoia Street
San Diego, CA 92109 / US
 [2015/15]
Representative(s)Sterling IP
Orion House
Bessemer Road
Welwyn Garden City AL7 1HH / GB
[2015/15]
Application number, filing date13847493.728.05.2013
WO2013US42912
Priority number, dateUS201261654019P31.05.2012         Original published format: US 201261654019 P
[2015/15]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2014062245
Date:24.04.2014
Language:EN
[2014/17]
Type: A2 Application without search report 
No.:EP2855523
Date:08.04.2015
Language:EN
The application published by WIPO in one of the EPO official languages on 24.04.2014 takes the place of the publication of the European patent application.
[2015/15]
Search report(s)International search report - published on:US09.10.2014
(Supplementary) European search report - dispatched on:EP20.01.2016
ClassificationIPC:C07K16/28, C07K16/22, A61K39/395, C12P21/08
[2016/07]
CPC:
C07K16/28 (EP,US); C07K16/22 (US); A61P35/00 (EP);
A61P35/02 (EP); C07K2317/21 (EP,US); C07K2317/76 (EP,US);
C07K2317/92 (EP,US) (-)
Former IPC [2015/15]C07K16/22, A61K39/395, C12P21/08
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2015/15]
TitleGerman:ANTIGENBINDENDE PROTEINE ZUM BINDEN VON DLL-4[2015/15]
English:ANTIGEN BINDING PROTEINS THAT BIND DLL-4[2015/15]
French:PROTÉINES LIANT L'ANTIGÈNE QUI LIENT DLL-4[2015/15]
Entry into regional phase30.12.2014National basic fee paid 
30.12.2014Search fee paid 
30.12.2014Designation fee(s) paid 
30.12.2014Examination fee paid 
Examination procedure30.12.2014Examination requested  [2015/15]
21.11.2016Amendment by applicant (claims and/or description)
03.01.2017Despatch of a communication from the examining division (Time limit: M06)
17.10.2017Reply to a communication from the examining division
22.11.2017Despatch of a communication from the examining division (Time limit: M04)
20.03.2018Reply to a communication from the examining division
01.12.2018Application deemed to be withdrawn, date of legal effect  [2019/20]
07.01.2019Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2019/20]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  03.01.2017
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
17.10.2017Request for further processing filed
17.10.2017Full payment received (date of receipt of payment)
Request granted
25.10.2017Decision despatched
The application is deemed to be withdrawn due to failure to indicate the wish to proceed further with the application
21.11.2016Request for further processing filed
21.11.2016Full payment received (date of receipt of payment)
Request granted
14.12.2016Decision despatched
The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
21.11.2016Request for further processing filed
21.11.2016Full payment received (date of receipt of payment)
Request granted
14.12.2016Decision despatched
Fees paidRenewal fee
20.05.2015Renewal fee patent year 03
27.05.2016Renewal fee patent year 04
26.05.2017Renewal fee patent year 05
Penalty fee
Additional fee for renewal fee
31.05.201806   M06   Not yet paid
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Documents cited:Search[A]WO2008042236  (ONCOMED PHARM INC [US], et al) [A] 1-12* example - *;
 [I]WO2008076379  (REGENERON PHARMA [US], et al) [I] 1-12 * example - *;
 [I]WO2010032060  (MEDIMMUNE LLC [US], et al) [I] 1-12 * examples 6,8,10 * * tables 14,18-21 *;
 [I]US2010292312  (YAN MINHONG [US], et al) [I] 1-12 * examples 2-8,10-12 *;
 [I]US2011117079  (BENATUIL LORENZO [US], et al) [I] 1-12 * example - * * tables 22,23 *
International search[A]US2003059937  (RUBEN STEVEN M [US], et al);
 [A]US2008025980  (HARDY BRITTA [IL], et al);
 [A]US2010292312  (YAN MINHONG [US], et al);
 [A]US2011117079  (BENATUIL LORENZO [US], et al);
 [A]  - AKAHORI, Y., "IMMUNOGLOBULIN HEAVY CHAIN VHDJ REGION, PARTIAL [HOMO SAPIENS]", GENBANK, (20020702), Database accession no. BAC01307.1, XP003034291
 [A]  - TIAN, C ET AL., "Immunodominance Of The VH1-46 Antibody Gene Segment In The Primary Repertoire Of Human Rotavirus-Specific B Cells Is Reduced In The Memory Compartment Through Somatic Mutation Of Nondominant Clones.", J IMMUNOL., (20080301), vol. 180, no. 5, pages 3279 - 3288, XP055174364
 [A]  - CHAPAL, N ET AL., "Thyroid Peroxidase Autoantibodies Obtained From Random Single Chain Fv Libraries Contain The Same Heavy/Light Chain Combinations As Occur In Vivo.", ENDOCRINOLOGY., (200111), vol. 142, no. 11, pages 4740 - 4750, XP055174390

DOI:   http://dx.doi.org/10.1210/en.142.11.4740
 [A]  - JIMENEZ-GOMEZ, G ET AL., "Modulated Selection Of IGHV Gene Somatic Hypermutation During Systemic Maturation Of Human Plasma Cells.", J LEUKOC BIOL., (201003), vol. 87, no. 3, pages 523 - 530, XP055174392

DOI:   http://dx.doi.org/10.1189/jlb.0709514
 [A]  - COMBRIATO, G ET AL., "V-Lambda and J-Lambda-C-Lambda Gene Segments Of The Human Immunoglobulin Lambda Light Chain Locus Are Separated By 14 Kb And Rearrange By A Deletion Mechanism.", EUROPEAN JOURNAL OF IMMUNOLOGY, (199106), vol. 21, no. 6, pages 1513 - 1522, XP055174401
 [A]  - SHRINER, A ET AL., "Analysis Of The Young And Elderly Variable Gene Repertoire In Response To Pneumococcal Polysaccharides Using A Reconstituted SCID Mouse Model.", VACCINE., (20061130), vol. 24, no. 49-50, pages 7159 - 7166, XP028011449

DOI:   http://dx.doi.org/10.1016/j.vaccine.2006.06.055
 [A]  - KUROSAWA, Y., "IMMUNOGLOBULIN KAPPA LIGHT CHAIN [HOMO SAPIENS]", GENBANK, (20090106), Database accession no. BAH04733.1, XP003034292
 [A]  - ADDERSON, E ET AL., "Immunoglobulin Light Chain Variable Region Gene Sequences For Human Antibodies To Haemophilus influenzae Type b Capsular Polysaccharide Are Dominated By A Limited Number Of V-Kappa and V-Lambda Segments And VJ Combinations.", J CLIN INVEST., (199203), vol. 89, no. 3, pages 729 - 738, XP009106771

DOI:   http://dx.doi.org/10.1172/JCI115649
 [A]  - TIAN, C ET AL., "Evidence For Preferential Ig Gene Usage And Differential TdT And Exonuclease Activities In Human Naive And Memory B Cells.", MOL IMMUNOL., (200703), vol. 44, no. 9, pages 2173 - 2183, XP005834035

DOI:   http://dx.doi.org/10.1016/j.molimm.2006.11.020
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.