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Extract from the Register of European Patents

EP About this file: EP2732817

EP2732817 - A compound for use in treating injury associated with exposure to phosgene or chlorine gas [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  30.06.2017
Database last updated on 14.09.2024
Most recent event   Tooltip10.07.2020Lapse of the patent in a contracting state
New state(s): IS		published on 12.08.2020  [2020/33]
Applicant(s)For all designated states
National Jewish Health
1400 Jackson Street
Denver, CO 80206 / US
[2014/21]
Inventor(s)01 / Day, Brian J.
1400 Jackson Street
Denver, CO 80206 / US
02 / White, Carl W.
1400 Jackson Street
Denver, CO 80206 / US
 [2014/21]
Representative(s)HGF
1 City Walk
Leeds LS11 9DX / GB
[N/P]
Former [2016/34]HGF Limited
1 City Walk
Leeds LS11 9DX / GB
Former [2014/21]HGF Limited
Belgrave Hall
Belgrave Street
Leeds
LS2 8DD / GB
Application number, filing date14154916.226.05.2009
[2014/21]
Priority number, dateUS20080055919P23.05.2008         Original published format: US 55919 P
[2014/21]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2732817
Date:21.05.2014
Language:EN
[2014/21]
Type: B1 Patent specification 
No.:EP2732817
Date:24.08.2016
Language:EN
[2016/34]
Search report(s)(Supplementary) European search report - dispatched on:EP01.04.2014
ClassificationIPC:A61K31/409, A61K31/4178, A61K31/427, A61K31/555, A61K45/06, A61P11/00, A61P17/00, A61P39/00
[2014/21]
CPC:
A61K31/4178 (EP,US); A61K31/409 (EP,US); A61K31/427 (EP,US);
A61K31/555 (EP,US); A61K45/06 (EP,US); A61P1/00 (EP);
A61P11/00 (EP); A61P17/00 (EP); A61P17/02 (EP);
A61P35/00 (EP); A61P39/00 (EP); A61P39/02 (EP);
A61P39/06 (EP); A61P43/00 (EP) (-)
C-Set:
A61K31/409, A61K2300/00 (EP,US);
A61K31/4178, A61K2300/00 (US,EP);
A61K31/427, A61K2300/00 (US,EP);
A61K31/555, A61K2300/00 (US,EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2016/34]
Former [2014/21]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:Verbindung zur Verwendung bei der Behandlung von Verletzungen aufgrund der Exposition gegenüber Phosgen oder Chlorgas[2014/21]
English:A compound for use in treating injury associated with exposure to phosgene or chlorine gas[2014/21]
French:Composé destiné à être utilisé dans le traitement d'une lésion associée à l'exposition à du phosgène ou du chlore gazeux[2014/21]
Examination procedure21.11.2014Amendment by applicant (claims and/or description)
21.11.2014Examination requested  [2015/01]
01.09.2015Despatch of a communication from the examining division (Time limit: M04)
04.01.2016Reply to a communication from the examining division
04.03.2016Communication of intention to grant the patent
28.06.2016Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
28.06.2016Fee for grant paid
28.06.2016Fee for publishing/printing paid
07.07.2016Information about intention to grant a patent
07.07.2016Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP09805313.5  / EP2300003
Opposition(s)26.05.2017No opposition filed within time limit [2017/31]
Fees paidRenewal fee
12.02.2014Renewal fee patent year 03
12.02.2014Renewal fee patent year 04
12.02.2014Renewal fee patent year 05
12.09.2014Renewal fee patent year 06
12.05.2015Renewal fee patent year 07
27.05.2016Renewal fee patent year 08
Penalty fee
Additional fee for renewal fee
31.05.201406   M06   Fee paid on   12.09.2014
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU26.05.2009
CY24.08.2016
CZ24.08.2016
EE24.08.2016
HR24.08.2016
LT24.08.2016
LV24.08.2016
MC24.08.2016
MK24.08.2016
PL24.08.2016
RO24.08.2016
SI24.08.2016
SK24.08.2016
TR24.08.2016
BG24.11.2016
NO24.11.2016
GR25.11.2016
IS24.12.2016
PT26.12.2016
[2020/33]
Former [2020/15]HU26.05.2009
CY24.08.2016
CZ24.08.2016
EE24.08.2016
HR24.08.2016
LT24.08.2016
LV24.08.2016
MC24.08.2016
MK24.08.2016
PL24.08.2016
RO24.08.2016
SI24.08.2016
SK24.08.2016
TR24.08.2016
BG24.11.2016
NO24.11.2016
GR25.11.2016
PT26.12.2016
Former [2019/52]HU26.05.2009
CY24.08.2016
CZ24.08.2016
EE24.08.2016
HR24.08.2016
LT24.08.2016
LV24.08.2016
MC24.08.2016
MK24.08.2016
PL24.08.2016
RO24.08.2016
SI24.08.2016
SK24.08.2016
BG24.11.2016
NO24.11.2016
GR25.11.2016
PT26.12.2016
Former [2019/46]HU26.05.2009
CY24.08.2016
CZ24.08.2016
EE24.08.2016
HR24.08.2016
LT24.08.2016
LV24.08.2016
MC24.08.2016
PL24.08.2016
RO24.08.2016
SI24.08.2016
SK24.08.2016
BG24.11.2016
NO24.11.2016
GR25.11.2016
PT26.12.2016
Former [2019/31]HU26.05.2009
CZ24.08.2016
EE24.08.2016
HR24.08.2016
LT24.08.2016
LV24.08.2016
MC24.08.2016
PL24.08.2016
RO24.08.2016
SI24.08.2016
SK24.08.2016
BG24.11.2016
NO24.11.2016
GR25.11.2016
PT26.12.2016
Former [2018/06]CZ24.08.2016
EE24.08.2016
HR24.08.2016
LT24.08.2016
LV24.08.2016
MC24.08.2016
PL24.08.2016
RO24.08.2016
SI24.08.2016
SK24.08.2016
BG24.11.2016
NO24.11.2016
GR25.11.2016
PT26.12.2016
Former [2017/37]CZ24.08.2016
EE24.08.2016
HR24.08.2016
LT24.08.2016
LV24.08.2016
PL24.08.2016
RO24.08.2016
SI24.08.2016
SK24.08.2016
BG24.11.2016
NO24.11.2016
GR25.11.2016
PT26.12.2016
Former [2017/32]CZ24.08.2016
EE24.08.2016
HR24.08.2016
LT24.08.2016
LV24.08.2016
PL24.08.2016
RO24.08.2016
SK24.08.2016
BG24.11.2016
NO24.11.2016
GR25.11.2016
PT26.12.2016
Former [2017/13]HR24.08.2016
LT24.08.2016
LV24.08.2016
NO24.11.2016
GR25.11.2016
PT26.12.2016
Former [2017/11]HR24.08.2016
LT24.08.2016
NO24.11.2016
GR25.11.2016
PT26.12.2016
Former [2017/09]LT24.08.2016
NO24.11.2016
Former [2017/07]LT24.08.2016
Documents cited:Search[YA]WO0043395  (NAT JEWISH MED & RES CENTER [US], et al) [Y] 1,3-7,9-12 * page 5, paragraph 1 * * page 6, paragraph 1 - page 8, paragraph 3 * * page 14, paragraph 1 - page 15, paragraph 1 * * claims 1, 2, 11, 17-19 * * figure 1C * [A] 2,8;
 [A]WO02060383  (NAT JEWISH MED & RES CENTER [US], et al) [A] 1-12 * page 2, paragraph 3 * * page 5, paragraph 2 - page 6, paragraph 2 * * page 8, paragraph 5 - page 9, paragraph 2 * * page 15, paragraph 2 - page 16, paragraph 1 * * page 19, paragraph 2 - page 20, paragraph 2 * * page 21, paragraph 1 * * claims 11, 15-19 * * figures 1A-H, 9 *;
 [A]WO02078670  (NEURON THERAPEUTICS INC [US]) [A] 1-12 * page 3, lines 11-20 * * page 4, line 14 * * page 6; table par. 1 * * claims 1, 16 *;
 [T]WO2011028935  (UNIV COLORADO [US], et al) [T] 1-12 * page 14, paragraph [0053] - page 15 * * page 18, paragraph [0066] * * page 19, paragraph [0070] - page 21, paragraph [0072] * * page 25, paragraph [0083] - page 26 * * page 28, paragraph [0092] * * claims 1, 11, 14-17 * * figure 1 *;
 [Y]  - AKDUR OKHAN ET AL, "Experimental Inhalation of Chlorine Gas Produced with a Different Method; Effects of N-Acetyl Cysteine on Acute Pulmonary Damage", TOXICOLOGY MECHANISMS AND METHODS, (20080101), vol. 18, no. 9, ISSN 1537-6524, pages 739 - 743, XP008168162 [Y] 1,3-7,9-12 * abstract * * page 739, paragraph l - page 740, column 1, paragraph 1 * * page 742, column 1, paragraph 2 * * page 742, column 2, paragraph 3 * * page 743, column 1, paragraph 2 *

DOI:   http://dx.doi.org/10.1080/15376510802354912
 [A]  - QIN XU-JUN ET AL, "[Effect of acute phosgene inhalation on antioxidant enzymes, nitric oxide and nitric-oxide synthase in rats].", MEDLINE, US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US, (200406), Database accession no. NLM15256156, XP002721669 [A] 1-12 * abstract *
    [ ] - QIN XU-JUN ET AL, "[Effect of acute phosgene inhalation on antioxidant enzymes, nitric oxide and nitric-oxide synthase in rats].", ZHONGHUA LAO DONG WEI SHENG ZHI YE BING ZA ZHI = ZHONGHUA LAODONG WEISHENG ZHIYEBING ZAZHI = CHINESE JOURNAL OF INDUSTRIAL HYGIENE AND OCCUPATIONAL DISEASES JUN 2004, (200406), vol. 22, no. 3, ISSN 1001-9391, pages 200 - 202
 [AP]  - GOULD NEAL S ET AL, "A Role for Mitochondrial Oxidative Stress in Sulfur Mustard Analog 2-Chloroethyl Ethyl Sulfide-Induced Lung Cell Injury and Antioxidant Protection", JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, (200903), vol. 328, no. 3, ISSN 0022-3565, pages 732 - 739 URL, XP002669844 [AP] 1-12 * abstract * * page 733, column 1, paragraphs 1-2 * * page 735, column 2, paragraph 4 * * figure 4 * * page 737, column 2, paragraph 2 * * page 739, column 1, paragraph 2 *

DOI:   http://dx.doi.org/10.1124/JPET.108.145037
 [AP]  - O'NEILL HEIDI C ET AL, "Catalytic Antioxidant AEOL 10150 Ameliorates 2-Chloroethyl Ethyl Sulfide (CEES)-Induced Lung Injury in Rats", FREE RADICAL BIOLOGY & MEDICINE, & 15TH ANNUAL MEETING OF THE SOCIETY-FOR-FREE-RADICAL-BIOLOGY-AND-MEDI CINE; INDIANAPOLIS, IN, USA; NOVEMBER 19 -23, 2008, (2008), vol. 45, no. Suppl. 1, ISSN 0891-5849, page S89, XP002669845 [AP] 1-12 * the whole document *
 [T]  - TOBY MCGOVERN ET AL, "AEOL10150: A novel therapeutic for rescue treatment after toxic gas lung injury", FREE RADICAL BIOLOGY AND MEDICINE, ELSEVIER SCIENCE, US, vol. 50, no. 5, doi:10.1016/J.FREERADBIOMED.2010.12.001, ISSN 0891-5849, (20101213), pages 602 - 608, (20101213), XP028133805 [T] 1-12 * abstract * * page 608, column 1, paragraphs 4-5 *

DOI:   http://dx.doi.org/10.1016/j.freeradbiomed.2010.12.001
by applicantUS4861760
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 US5212162
 US5403841
 WO9605309
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 US2007149498
    - BERGE ET AL., "Pharmaceutical Salts", JOURNAL OFPHARMACEUTICAL SCIENCE, (1977), vol. 66, doi:doi:10.1002/jps.2600660104, pages 1 - 19, XP002675560

DOI:   http://dx.doi.org/10.1002/jps.2600660104
    - ALFONSO R. GENNARO, Pharmaceutical Sciences 17th Ed.,, MACK PUB. CO.
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.