blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP2805726

EP2805726 - Macrocyclic hepatitis C serine protease inhibitors [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  08.03.2019
Database last updated on 03.09.2024
FormerThe patent has been granted
Status updated on  30.03.2018
FormerGrant of patent is intended
Status updated on  20.11.2017
FormerExamination is in progress
Status updated on  31.10.2016
Most recent event   Tooltip08.03.2019No opposition filed within time limitpublished on 10.04.2019  [2019/15]
Applicant(s)For all designated states
Enanta Pharmaceuticals, Inc.
500 Arsenal Street
Watertown, MA 02472 / US
For all designated states
AbbVie Ireland Unlimited Company
70 Sir John Rogerson's Quay
Dublin 2 / IE
[2017/17]
Former [2014/48]For all designated states
Enanta Pharmaceuticals, Inc.
500 Arsenal Street
Watertown, MA 02472 / US
For all designated states
AbbVie Bahamas Limited
Sassoon House
Shirley Street & Victoria Avenue
New Providence, Nassau / BS
Inventor(s)01 / Ku, Yiyin
23 River
Buffalo Grove, IL 60089 / US
02 / Or, Yat, Sun
169 Fayette Street
Watertown, MA 02472 / US
03 / Wagaw, Sable, H.
251 E Washington Ave
Lake Bluff, IL 60044-2156 / US
04 / Engstrom, Ken
96 Alexandria Ct.
Mundelein, IL 60060 / US
05 / Grieme, Tim
4942 Winchester Ave. Apt. 2
Chicago, IL 60604 / US
06 / Sheikh, Ahmad
700 Pine St.
Deerfield, IL 60015 / US
07 / Mei, Jianzhang
319 Whitmore Lane
Lake Forest, IL 60045 / US
08 / McDaniel, Keith, F.
26029 W. Laurel Ct.
Wauconda, IL 60084 / US
09 / Chen, Hui-ju
4 Crows Nest Ct.
Grayslake, IL 60030 / US
10 / Shanley, Jason, P.
902 N. Winchester Ave. Floor 3
Chicago, IL 60622 / US
11 / Kempf, Dale, J.
256 Tyler Ct.
Libertyville, IL 60048 / US
12 / Grampovnik, David, J.
2500 N. Walnut St.
Waukegan, IL 02451 / US
13 / Gai, Yonghua
13 Valley View Drive
North Grafton, MA 01536 / US
14 / Sun, Ying
220 School Street ST 6
Waltham, MA 02451 / US
15 / Liu, Dong
20 Rich St. Apt. 2
Newton, MA 02451 / US
 [2018/18]
Former [2014/48]01 / Ku, Yiyin
23 River
Buffalo Grove, IL 60089 / US
02 / Or, Yat, Sun
169 Fayette Street
Watertown, MA 02472 / US
03 / Wagaw, Sable, H.
2311 Ridgeway
Evanston, IL 60201 / US
04 / Engstrom, Ken
96 Alexandria Ct.
Mundelein, IL 60060 / US
05 / Grieme, Tim
4942 Winchester Ave. Apt. 2
Chicago, IL 60604 / US
06 / Sheikh, Ahmad
700 Pine St.
Deerfield, IL 60015 / US
07 / Mei, Jianzhang
319 Whitmore Lane
Lake Forest, IL 60045 / US
08 / McDaniel, Keith, F.
26029 W. Laurel Ct.
Wauconda, IL 60084 / US
09 / Chen, Hui-ju
4 Crows Nest Ct.
Grayslake, IL 60030 / US
10 / Shanley, Jason, P.
902 N. Winchester Ave. Floor 3
Chicago, IL 60622 / US
11 / Kempf, Dale, J.
256 Tyler Ct.
Libertyville, IL 60048 / US
12 / Grampovnik, David, J.
2500 N. Walnut St.
Waukegan, IL 02451 / US
13 / Gai, Yonghua
13 Valley View Drive
North Grafton, MA 01536 / US
14 / Sun, Ying
220 School Street ST 6
Waltham, MA 02451 / US
15 / Liu, Dong
20 Rich St. Apt. 2
Newton, MA 02451 / US
Representative(s)Modiano, Micaela Nadia
Modiano & Partners
Thierschstrasse 11
80538 München / DE
[2014/48]
Application number, filing date14181565.410.09.2009
[2014/48]
Priority number, dateUS20080191725P11.09.2008         Original published format: US 191725 P
US20090209689P10.03.2009         Original published format: US 209689 P
[2014/48]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2805726
Date:26.11.2014
Language:EN
[2014/48]
Type: B1 Patent specification 
No.:EP2805726
Date:02.05.2018
Language:EN
[2018/18]
Search report(s)(Supplementary) European search report - dispatched on:EP28.10.2014
ClassificationIPC:A61K38/00, A61K38/12, C07D487/04
[2014/48]
CPC:
C07D487/04 (EP,KR,US); C07K5/0804 (CN); C07K1/113 (US);
A61K31/407 (KR); A61K31/4709 (KR); A61P1/16 (EP);
A61P31/12 (EP); A61P31/14 (EP); A61P31/18 (EP);
A61P43/00 (EP); A61K38/00 (CN) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2015/28]
Former [2014/48]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  SM,  TR 
TitleGerman:Makrocyclische Hepatitis-C-Serinprotease-Inhibitoren[2014/48]
English:Macrocyclic hepatitis C serine protease inhibitors[2014/48]
French:Inhibiteurs macrocycliques de la protéase de la sérine de l'hépatite C[2014/48]
Examination procedure25.05.2015Amendment by applicant (claims and/or description)
25.05.2015Examination requested  [2015/28]
24.06.2016Despatch of a communication from the examining division (Time limit: M04)
20.10.2016Reply to a communication from the examining division
07.04.2017Despatch of a communication from the examining division (Time limit: M02)
14.06.2017Reply to a communication from the examining division
14.07.2017Despatch of a communication from the examining division (Time limit: M02)
18.09.2017Reply to a communication from the examining division
21.11.2017Communication of intention to grant the patent
23.03.2018Fee for grant paid
23.03.2018Fee for publishing/printing paid
23.03.2018Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP09813360.6  / EP2340029
EP12160779.0  / EP2468285
Opposition(s)05.02.2019No opposition filed within time limit [2019/15]
Fees paidRenewal fee
20.08.2014Renewal fee patent year 03
20.08.2014Renewal fee patent year 04
20.08.2014Renewal fee patent year 05
20.08.2014Renewal fee patent year 06
08.09.2015Renewal fee patent year 07
08.09.2016Renewal fee patent year 08
11.09.2017Renewal fee patent year 09
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[XYI]WO2004093798  (ENANTA PHARM INC [US], et al) [X] 1-4,13-16 * the whole document * [Y] 1-4,11,13-15 [I] 1-16;
 [Y]WO2007001406  (CHIRON CORP [US], et al) [Y] 1-4,11,13,14 * page 49; claims 1, 33-35 *;
 [Y]WO2007014926  (TIBOTEC PHARM LTD [IE], et al) [Y] 1-4,11,13-15 * pages 7, 35; claims 1, 20-23 *;
 [XPI]WO2009073719  (ENANTA PHARM INC [US], et al) [XP] 1-4,13,14 * examples 32a, 32b; claims 1, 4-5 *[I] 1-16
by applicantUS5861297
 WO9907733
 WO9950230
 WO0009543
 WO0059929
 US2002037998
 US6921753
 US2007043180
    - S. TAN; A. PAUSE; Y. SHI; N. SONENBERG, "Hepatitis C Therapeutics: Current Status and Emerging Strategies", NATURE REV. DRNG DISCOV., (2002), vol. 1, doi:doi:10.1038/nrd937, pages 867 - 881, XP001204206

DOI:   http://dx.doi.org/10.1038/nrd937
    - S. TAN; A. PAUSE; Y. SHI; N. SONENBERG, "Hepatitis C Therapeutics: Current Status and Emerging Strategies", NATURE REV. DRUG DISCOV., (2002), vol. 1, doi:doi:10.1038/nrd937, pages 867 - 881, XP001204206

DOI:   http://dx.doi.org/10.1038/nrd937
    - J. PHARMACEUTICAL SCIENCES, (1977), vol. 66, pages 1 - 19
    - WIDDER, ET AL., Methods in Enzymology, ACADEMIC PRESS, (1985), vol. 4
    - "chapter 5", KROGSGAARD-LARSEN, ET AL., Design and Application of Prodrugs, Textbook of Drug Design and Development, (1991), pages 113 - 191
    - BUNDGAARD ET AL., JOURNAL OF DRUG DELIVER REVIEWS, (1992), vol. 8, pages 1 - 38
    - BUNDGAARD, J., PHARMACEUTICAL SCIENCES, (1988), vol. 77, page 285
    - J. MED. CHEM., (1996), vol. 39, page 10
    - LOHMANN ET AL., SCIENCE, (1999), vol. 285, no. 5424, pages 110 - 113
    - BLIGHT ET AL., J VIROL, (2003), vol. 77, no. 5, pages 3181 - 3190
    - BLIGHT ET AL., SCIENCE, (2000), vol. 290, no. 5498, pages 1972 - 1974
    - MO ET AL., ANTIMICROB AGENTS CHEMOTHER, (2005), vol. 49, no. 10, pages 4305 - 4314
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.