blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News flashes

New version of the European Patent Register - SPC information for Unitary Patents.

2024-03-06

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP2865381

EP2865381 - ITK inhibitors for treating blood cell malignancies [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  13.04.2018
Database last updated on 06.07.2024
FormerRequest for examination was made
Status updated on  01.01.2018
Most recent event   Tooltip13.04.2018Application deemed to be withdrawnpublished on 16.05.2018  [2018/20]
Applicant(s)For all designated states
Pharmacyclics, Inc.
995 East Arques Avenue
Sunnyvale, CA 94085 / US
[2015/18]
Inventor(s)01 / Flynn, Gary A
9750 North Cliff View Place
Tuscan, AZ 85737 / US
02 / Lee, Sandra Aeyoung
Apartment C
15003 Dickens Street, Apt. C
Sherman Oaks, CA 91403 / US
03 / Faris, Mary
2538 Almaden Court
Los Angeles, CA 90077 / US
04 / Brandt, David William
4426 Daisy Court
Moorpark, CA 93021 / US
05 / Chakravarty, Subrata
28233 Canterbury Court
Valencia, CA 91354 / US
 [2015/18]
Representative(s)HGF
4th Floor
Merchant Exchange
17-19 Whitworth Street West
Manchester M1 5WG / GB
[N/P]
Former [2015/18]Shah, Punita
HGF Limited
4th Floor, Merchant Exchange
17-19 Whitworth Street West
Manchester M1 5WG / GB
Application number, filing date14183381.418.05.2007
[2015/18]
Priority number, dateUS20060801074P18.05.2006         Original published format: US 801074 P
US20060869664P12.12.2006         Original published format: US 869664 P
[2015/18]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2865381
Date:29.04.2015
Language:EN
[2015/18]
Search report(s)(Supplementary) European search report - dispatched on:EP31.03.2015
ClassificationIPC:A61K31/445, A61K31/495, A61K31/4035, A61K31/472, A61K31/341, A61K31/5375, A61K31/496, A61K31/5377, A61K31/54, A61K31/551, A61P37/00, A61K31/33
[2015/18]
CPC:
A61K31/538 (EP,US); A61K31/137 (EP,US); A61K31/33 (EP,US);
A61K31/40 (EP,US); A61K31/4035 (EP,US); A61K31/445 (EP,US);
A61K31/47 (EP,US); A61K31/495 (EP,US); A61K31/5375 (EP,US);
A61K31/5377 (EP,US); A61P1/02 (EP); A61P1/04 (EP);
A61P1/16 (EP); A61P11/06 (EP); A61P13/12 (EP);
A61P17/00 (EP); A61P19/02 (EP); A61P21/00 (EP);
A61P25/00 (EP); A61P25/02 (EP); A61P29/00 (EP);
A61P3/10 (EP); A61P35/00 (EP); A61P35/02 (EP);
A61P37/00 (EP); A61P37/02 (EP); A61P37/06 (EP);
A61P43/00 (EP); A61P7/00 (EP); A61P7/02 (EP);
A61P7/04 (EP); A61P7/06 (EP); C07D207/08 (EP,US);
C07D207/14 (EP,US); C07D209/44 (EP,US); C07D211/10 (EP,US);
C07D211/26 (EP,US); C07D211/30 (EP,US); C07D217/04 (EP,US);
C07D265/36 (EP,US); C07D295/108 (EP,US); C07D295/185 (EP,US);
C07D295/192 (EP,US); C07D295/215 (EP,US); C07D307/52 (EP,US);
C07D307/80 (EP,US); C07D317/54 (EP,US); C07D319/18 (EP,US);
C07D333/56 (EP,US); C07D401/04 (EP,US); C07D401/06 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2015/18]
TitleGerman:ITK-Hemmer zur Behandlung von bösartigen Blutzellenerkrankungen[2015/18]
English:ITK inhibitors for treating blood cell malignancies[2015/18]
French:Inhibiteurs de ITK pour le traitement des cancers des cellules sanguines[2015/18]
Examination procedure03.09.2014Examination requested  [2015/18]
10.02.2016Amendment by applicant (claims and/or description)
01.12.2017Application deemed to be withdrawn, date of legal effect  [2018/20]
02.01.2018Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2018/20]
Parent application(s)   TooltipEP07795056.6  / EP2027087
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
10.02.2016Request for further processing filed
10.02.2016Full payment received (date of receipt of payment)
Request granted
22.02.2016Decision despatched
Fees paidRenewal fee
03.09.2014Renewal fee patent year 03
03.09.2014Renewal fee patent year 04
03.09.2014Renewal fee patent year 05
03.09.2014Renewal fee patent year 06
03.09.2014Renewal fee patent year 07
03.09.2014Renewal fee patent year 08
12.05.2015Renewal fee patent year 09
10.05.2016Renewal fee patent year 10
Penalty fee
Additional fee for renewal fee
31.05.201711   M06   Not yet paid
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[X]US2004067990  (BARRISH JOEL C [US], et al) [X] 1,2,6 * paragraphs [0005] , [0176] *;
 [XY]  - BROWN G R G R ET AL, "Naphthyl ketones: a new class of Janus kinase 3 inhibitors", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, AMSTERDAM, NL, (20000301), vol. 10, no. 6, doi:10.1016/S0960-894X(00)00051-2, ISSN 0960-894X, pages 575 - 579, XP004190942 [X] 13-15 * tables 1,2 * [Y] 1-20

DOI:   http://dx.doi.org/10.1016/S0960-894X(00)00051-2
 [X]  - HUANG YUNSHENG ET AL, "Synthesis and hypolipidemic evaluation of beta-alkylaminopropiophenone and beta-alkylaminopropio-2'-naphthone derivatives in rodents", DIE PHARMAZIE, GOVI VERLAG PHARMAZEUTISCHER VERLAG GMBH, ESCHBORN, DE, (19960101), vol. 51, no. 4, ISSN 0031-7144, pages 199 - 206, XP001526819 [X] 13-15 * table 1 *
 [Y]  - SUDBECK E A ET AL, "STRUCTURE-BASED DESIGN OF SPECIFIC INHIBITORS OF JANUS KINASE 3 AS APOPTOSIS-INDUCING ANTILEUKEMIC AGENTS", CLINICAL CANCER RESEARCH, THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, (19990601), vol. 5, no. 6, ISSN 1078-0432, pages 1569 - 1582, XP000939043 [Y] 1-20 * the whole document *
 [Y]  - AMIN HESHAM M ET AL, "Inhibition of JAK3 induces apoptosis and decreases anaplastic lymphoma kinase activity in anaplastic large cell lymphoma.", ONCOGENE 21 AUG 2003, (20030821), vol. 22, no. 35, ISSN 0950-9232, pages 5399 - 5407, XP002736144 [Y] 1-20 * the whole document *

DOI:   http://dx.doi.org/10.1038/sj.onc.1206849
by applicantUS2005215582
 US2004077695
 US3845770
 US3916899
 US3536809
 US3598123
 US3944064
 US4008719
    - MAO ET AL., J. BIOL. CHEM., (2001), vol. 276, pages 41435 - 41443
    - BROWN ET AL., J. BIOL. CHEM., (2004), vol. 279, pages 18727 - 18732
    - SLICHENMEYER, W.J.; ELLIOTT, W.C.; FRY, D.W., SEMIN. ONEOL., (2001), vol. 28, pages 80 - 85
    - SHIMAMURA, T; JI, H.; MINAMI, Y.; THOMAS, R. K.; LOWELL, A.M.; SHA, K.; GREULICH, H.; GLATT, K.A.; MEYERSON, M.; SHAPIRO, I., CANCER RES., (2006), vol. 66, pages 6487 - 6491
    - EXP HEMATOL., (2006), vol. 34, pages 284 - 88
    - LEUK. LYMPHOMA., (2006), vol. 47, pages 521 - 29
    - LEUK. LYMPHOMA., (1992), vol. 7, pages 79 - 86
    - J. VIROL., (2006), vol. 79, pages 9449 - 57
    - NEOPLASIA, (2005), vol. 7, pages 984 - 91
    - OLIGONUCLEOTIDES, vol. 15, pages 85 - 93
    - TRANSFUS. APHER. SCI., (2005), vol. 32, pages 197 - 203
    - NATURE, (1991), vol. 17, pages 254 - 56
    - CELL. MOL. IMMUNOL., (2005), vol. 2, pages 461 - 65
    - PROC. NATL. ACAD. SCI. USA, (2005), vol. 102, pages 11823 - 28
    - ARTHRITIS RHEUM., (2004), vol. 50, pages 3250 - 59
    - CLIN. EXP. IMMUNOL., (1995), vol. 99, pages 294 - 302
    - J. CLIN. INVEST., (2006), vol. 116, pages 905 - 15
    - J. CLIN. INVEST., (2006), vol. 116, pages 961 - 973
    - ENDOCRINOL., (2006), vol. 147, pages 754 - 61
    - EXP MOL PATHOL., (2004), vol. 77, pages 161 - 67
    - J. RHEUMATOL. SUPPL., (1983), vol. 11, pages 114 - 17
    - RHEUMATOL., (2005), vol. 32, pages 1071 - 75
    - BRAIN PATHOL., (2002), vol. 12, pages 420 - 29
    - J. CLIN. INVEST., (2002), vol. 110, pages 955 - 63
    - VET. PATHOL., (1995), vol. 32, pages 337 - 45
    - IMMUNOL. INVEST., (2006), vol. 3, pages 47 - 61
    - ARCH. DERMATOL. RES., (2006), vol. 297, pages 333 - 44
    - J. EXP. MED., (2000), vol. 191, pages 899 - 906
    - J. VET. MED. SCI., (2006), vol. 68, pages 65 - 68
    - LIVER INT., (2005), vol. 25, pages 595 - 603
    - J. CLIN. INVEST., (1993), vol. 91, pages 1507 - 15
    - J. IMMUNOL., (2002), vol. 169, pages 4889 - 96
    - ISR. J. MED. SCI., (1979), vol. 15, pages 348 - 55
    - SURGERY, (2000), vol. 128, pages 999 - 1006
    - J. NEUROIMMUNOL., (1999), vol. 98, pages 130 - 35
    - AM. J. PATHOL., (1985), vol. 120, pages 323 - 25
    - BONE, (1997), vol. 20, pages 515 - 20
    - HAEMOPHILIA, (2005), vol. 11, pages 227 - 32
    - PROC. NATL. ACAD. SCI. USA, (1997), vol. 94, pages 233 - 36
    - PAIN, (2004), vol. 110, pages 56 - 63
    - ANN. NEUROL., (2001), vol. 49, pages 712 - 20
    - J. NEUROSCI. RES:, (1996), vol. 44, pages 58 - 65
    - EUR. J. IMMUNOL., (2002), vol. 32, pages 1147 - 56
    - HAEMATOLOGICA, (2003), vol. 88, pages 679 - 87
    - CURR. TOP. MICROBIOL. IMMUNOL., (2005), vol. 293, pages 153 - 77
    - J. IMMUNOL., (2005), vol. 175, pages 2475 - 83
    - INFLAMM. RES., (2004), vol. 53, pages 72 - 77
    - VET. PATHOL., (2006), vol. 43, pages 2 - 14
    - J. BIOL. CHEM., (2001), vol. 276, page 13821
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.