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Extract from the Register of European Patents

EP About this file: EP2839860

EP2839860 - Pyrrolobenzodiazepines and conjugates thereof [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  06.03.2020
Database last updated on 24.04.2024
FormerThe patent has been granted
Status updated on  29.03.2019
FormerGrant of patent is intended
Status updated on  01.01.2019
FormerExamination is in progress
Status updated on  15.01.2017
Most recent event   Tooltip06.03.2020No opposition filed within time limitpublished on 08.04.2020  [2020/15]
Applicant(s)For all designated states
MedImmune Limited
Milstein Building Granta Park Cambridge
CB21 6GH / GB
[2015/43]
Former [2015/09]For all designated states
Spirogen Sàrl
Rue Saint-Pierre2
1003 Lausanne / CH
Inventor(s)01 / Howard, Philip Wilson
Spirogen Limited The QMB Innovation Centre
42 New Road
London, Greater London E1 2AX / GB
 [2015/09]
Representative(s)Mewburn Ellis LLP
Aurora Building
Counterslip
Bristol BS1 6BX / GB
[N/P]
Former [2019/18]Mewburn Ellis LLP
City Tower
40 Basinghall Street
London EC2V 5DE / GB
Former [2015/09]Watson, Robert James
Mewburn Ellis LLP
33 Gutter Lane
London EC2V 8AS / GB
Application number, filing date14191079.411.10.2013
[2015/09]
Priority number, dateUS201261712928P12.10.2012         Original published format: US 201261712928 P
[2015/09]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2839860
Date:25.02.2015
Language:EN
[2015/09]
Type: B1 Patent specification 
No.:EP2839860
Date:01.05.2019
Language:EN
[2019/18]
Search report(s)(Supplementary) European search report - dispatched on:EP22.01.2015
ClassificationIPC:A61K47/68, A61K47/65, A61P39/00, A61P35/00, C07D487/04, C07D519/00
[2018/52]
CPC:
A61K47/6855 (EP,KR,US); C07D487/04 (EP,EA,KR,US); C07D519/00 (EP,EA,US);
A61K39/395 (KR); A61K45/06 (KR,US); A61K47/65 (EP,KR,US);
A61K47/6803 (EP,KR,US); A61K47/6891 (KR); A61P35/00 (EP,EA);
A61P39/00 (EP); A61K2039/505 (KR); A61K2300/00 (KR);
Y02P20/582 (EP,KR,US) (-)
Former IPC [2015/09]A61P39/00, A61K47/48, A61P35/00
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2015/40]
Former [2015/09]AL,  AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  RS,  SE,  SI,  SK,  SM,  TR 
Extension statesBA19.08.2015
ME19.08.2015
TitleGerman:Pyrrolobenzodiazepine und Konjugate davon[2015/09]
English:Pyrrolobenzodiazepines and conjugates thereof[2015/09]
French:Pyrrolobenzodiazépines et ses conjugués[2015/09]
Examination procedure19.08.2015Amendment by applicant (claims and/or description)
19.08.2015Examination requested  [2015/40]
06.06.2016Despatch of a communication from the examining division (Time limit: M06)
16.01.2017Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
24.03.2017Reply to a communication from the examining division
13.03.2018Cancellation of oral proceeding that was planned for 13.04.2018
21.03.2018Despatch of a communication from the examining division (Time limit: M04)
13.04.2018Date of oral proceedings (cancelled)
03.07.2018Reply to a communication from the examining division
02.01.2019Communication of intention to grant the patent
20.03.2019Fee for grant paid
20.03.2019Fee for publishing/printing paid
20.03.2019Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP13780100.7  / EP2766048
Opposition(s)04.02.2020No opposition filed within time limit [2020/15]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
24.03.2017Request for further processing filed
24.03.2017Full payment received (date of receipt of payment)
Request granted
07.04.2017Decision despatched
Fees paidRenewal fee
26.10.2015Renewal fee patent year 03
24.10.2016Renewal fee patent year 04
25.10.2017Renewal fee patent year 05
25.10.2018Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[YD]WO2011130598  (SPIROGEN LTD [GB], et al) [YD] 1-15 * compound 80 (page 149, 134) *;
 [Y]  - STEPHEN C. ALLEY ET AL, "Contribution of Linker Stability to the Activities of Anticancer Immunoconjugates", BIOCONJUGATE CHEMISTRY, (20080301), vol. 19, no. 3, doi:10.1021/bc7004329, ISSN 1043-1802, pages 759 - 765, XP055037546 [Y] 1-15 * abstract, section "Discussion" *

DOI:   http://dx.doi.org/10.1021/bc7004329
 [Y]  - Richard P Haughland, "Section 2.1: Introduction to Thiol Modification and Detection", The Handbook - A guide to Fluorescent Probes and Labeling Technologies, Invitrogen Corp., (20050101), pages 96 - 98, XP055096281 [Y] 1-15 * section "Iodoacetamides" and "Maleimides" *
Examination   - Greg T Hermanson, "Thiol-Reactive Chemical Reactions", Bioconjugate Techniques, SAN DIEGO, CA, US, ACADEMIC PRESS, (19960101), pages 146 - 148, XP055275993
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