EP2956146 - STEM CELL MICROPARTICLES AND MIRNA [Right-click to bookmark this link] | Status | Patent maintained as amended Status updated on 15.07.2022 Database last updated on 11.05.2024 | |
Former | The patent has been granted Status updated on 05.10.2018 | ||
Former | Grant of patent is intended Status updated on 26.09.2018 | ||
Former | Examination is in progress Status updated on 21.08.2018 | ||
Former | Grant of patent is intended Status updated on 17.05.2018 | ||
Former | Examination is in progress Status updated on 28.04.2017 | Most recent event Tooltip | 15.07.2022 | Patent maintained (B2 publication) | published on 17.08.2022 [2022/33] | Applicant(s) | For all designated states Reneuron Limited 10 Nugent Road Surrey Research Park Guildford Surrey GU2 7AF / GB | [2015/52] | Inventor(s) | 01 /
STEVANATO, Lara Reneuron Limited 10 Nugent Road Surrey Research Park Guildford Surrey GU2 7AF / GB | 02 /
CORTELING, Randolph Reneuron Limited 10 Nugent Road Surrey Research Park Guildford Surrey GU2 7AF / GB | 03 /
SINDEN, John Reneuron Limited 10 Nugent Road Surrey Research Park Guildford Surrey GU2 7AF / GB | [2015/52] | Representative(s) | Elkington and Fife LLP Prospect House 8 Pembroke Road Sevenoaks, Kent TN13 1XR / GB | [2022/33] |
Former [2018/45] | Truscott, Glyn John Elkington and Fife LLP Thavies Inn House 3-4 Holborn Circus London EC1N 2HA / GB | ||
Former [2015/52] | Carpmaels & Ransford LLP One Southampton Row London WC1B 5HA / GB | Application number, filing date | 14706666.6 | 12.02.2014 | [2015/52] | WO2014GB50411 | Priority number, date | GB20130002468 | 12.02.2013 Original published format: GB 201302468 | [2015/52] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2014125276 | Date: | 21.08.2014 | Language: | EN | [2014/34] | Type: | A1 Application with search report | No.: | EP2956146 | Date: | 23.12.2015 | Language: | EN | The application published by WIPO in one of the EPO official languages on 21.08.2014 takes the place of the publication of the European patent application. | [2015/52] | Type: | B1 Patent specification | No.: | EP2956146 | Date: | 07.11.2018 | Language: | EN | [2018/45] | Type: | B2 New European patent specification | No.: | EP2956146 | Date: | 17.08.2022 | Language: | EN | [2022/33] | Search report(s) | International search report - published on: | EP | 21.08.2014 | Classification | IPC: | A61P25/28, A61P11/00, A61P9/00, A61K35/30, A61K31/713, A61K31/7105 | [2018/22] | CPC: |
A61K31/7105 (EP,US);
A61K31/713 (EP,US);
A61K35/30 (EP,US);
A61P1/04 (EP);
A61P11/00 (EP);
A61P11/06 (EP);
A61P17/02 (EP);
A61P19/02 (EP);
A61P21/02 (EP);
A61P25/00 (EP);
A61P25/16 (EP);
A61P25/18 (EP);
A61P25/24 (EP);
A61P25/28 (EP);
A61P27/02 (EP);
A61P29/00 (EP);
A61P3/00 (EP);
A61P3/10 (EP);
A61P37/06 (EP);
A61P9/00 (EP);
A61P9/04 (EP);
| C-Set: |
A61K31/713, A61K2300/00 (EP,US)
|
Former IPC [2015/52] | A61K31/711, A61P25/28, A61P11/00, A61P9/00, A61K35/30 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2015/52] | Title | German: | STAMMZELLENMIKROPARTIKEL UND MIRNA | [2015/52] | English: | STEM CELL MICROPARTICLES AND MIRNA | [2015/52] | French: | MICROPARTICULES DE CELLULES SOUCHES ET MIARN | [2015/52] | Biological material | This application mentions deposited biological material, check the file for details | Entry into regional phase | 03.09.2015 | National basic fee paid | 03.09.2015 | Designation fee(s) paid | 03.09.2015 | Examination fee paid | Examination procedure | 03.09.2015 | Examination requested [2015/52] | 14.04.2016 | Amendment by applicant (claims and/or description) | 28.04.2017 | Despatch of a communication from the examining division (Time limit: M04) | 06.09.2017 | Reply to a communication from the examining division | 18.05.2018 | Communication of intention to grant the patent | 16.08.2018 | Fee for grant paid | 16.08.2018 | Fee for publishing/printing paid | 20.08.2018 | Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO | 26.09.2018 | Information about intention to grant a patent | 26.09.2018 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 28.04.2017 | Opposition(s) | Opponent(s) | 01
07.08.2019
ADMISSIBLE Pajaro Limited 12 New Fetter Lane London EC4A 1JP / GB Opponent's representative Bird & Bird LLP Maximiliansplatz 22 80333 München / DE | [2019/37] | 22.08.2019 | Invitation to proprietor to file observations on the notice of opposition | 31.12.2019 | Reply of patent proprietor to notice(s) of opposition | 17.09.2020 | Cancellation of oral proceeding that was planned for 17.11.2020 | 17.11.2020 | Date of oral proceedings | 15.11.2021 | Legal effect of interlocutory decision in opposition | 15.11.2021 | Date of oral proceedings | 13.12.2021 | Despatch of interlocutory decision in opposition | 13.12.2021 | Despatch of minutes of oral proceedings | 31.03.2022 | Despatch of communication that the patent will be maintained as amended | 07.07.2022 | Fee for printing new specification paid | Fees paid | Renewal fee | 10.02.2016 | Renewal fee patent year 03 | 10.02.2017 | Renewal fee patent year 04 | 14.02.2018 | Renewal fee patent year 05 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 12.02.2014 | AL | 07.11.2018 | AT | 07.11.2018 | CY | 07.11.2018 | CZ | 07.11.2018 | DK | 07.11.2018 | EE | 07.11.2018 | FI | 07.11.2018 | HR | 07.11.2018 | IT | 07.11.2018 | LT | 07.11.2018 | LV | 07.11.2018 | MC | 07.11.2018 | MK | 07.11.2018 | NL | 07.11.2018 | PL | 07.11.2018 | RO | 07.11.2018 | RS | 07.11.2018 | SE | 07.11.2018 | SI | 07.11.2018 | SK | 07.11.2018 | SM | 07.11.2018 | TR | 07.11.2018 | BG | 07.02.2019 | NO | 07.02.2019 | GR | 08.02.2019 | IE | 12.02.2019 | LU | 12.02.2019 | MT | 12.02.2019 | BE | 28.02.2019 | CH | 28.02.2019 | LI | 28.02.2019 | IS | 07.03.2019 | PT | 07.03.2019 | [2022/31] |
Former [2021/32] | HU | 12.02.2014 | |
AL | 07.11.2018 | ||
AT | 07.11.2018 | ||
CY | 07.11.2018 | ||
CZ | 07.11.2018 | ||
DK | 07.11.2018 | ||
EE | 07.11.2018 | ||
FI | 07.11.2018 | ||
HR | 07.11.2018 | ||
IT | 07.11.2018 | ||
LT | 07.11.2018 | ||
LV | 07.11.2018 | ||
MC | 07.11.2018 | ||
NL | 07.11.2018 | ||
PL | 07.11.2018 | ||
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SM | 07.11.2018 | ||
TR | 07.11.2018 | ||
BG | 07.02.2019 | ||
NO | 07.02.2019 | ||
GR | 08.02.2019 | ||
IE | 12.02.2019 | ||
LU | 12.02.2019 | ||
MT | 12.02.2019 | ||
BE | 28.02.2019 | ||
CH | 28.02.2019 | ||
LI | 28.02.2019 | ||
IS | 07.03.2019 | ||
PT | 07.03.2019 | ||
Former [2021/26] | AL | 07.11.2018 | |
AT | 07.11.2018 | ||
CY | 07.11.2018 | ||
CZ | 07.11.2018 | ||
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MC | 07.11.2018 | ||
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PL | 07.11.2018 | ||
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SK | 07.11.2018 | ||
SM | 07.11.2018 | ||
TR | 07.11.2018 | ||
BG | 07.02.2019 | ||
NO | 07.02.2019 | ||
GR | 08.02.2019 | ||
IE | 12.02.2019 | ||
LU | 12.02.2019 | ||
MT | 12.02.2019 | ||
BE | 28.02.2019 | ||
CH | 28.02.2019 | ||
LI | 28.02.2019 | ||
IS | 07.03.2019 | ||
PT | 07.03.2019 | ||
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MC | 07.11.2018 | ||
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PL | 07.11.2018 | ||
RO | 07.11.2018 | ||
RS | 07.11.2018 | ||
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SI | 07.11.2018 | ||
SK | 07.11.2018 | ||
SM | 07.11.2018 | ||
TR | 07.11.2018 | ||
BG | 07.02.2019 | ||
NO | 07.02.2019 | ||
GR | 08.02.2019 | ||
IE | 12.02.2019 | ||
LU | 12.02.2019 | ||
MT | 12.02.2019 | ||
BE | 28.02.2019 | ||
CH | 28.02.2019 | ||
LI | 28.02.2019 | ||
IS | 07.03.2019 | ||
PT | 07.03.2019 | ||
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SK | 07.11.2018 | ||
SM | 07.11.2018 | ||
TR | 07.11.2018 | ||
BG | 07.02.2019 | ||
NO | 07.02.2019 | ||
GR | 08.02.2019 | ||
IE | 12.02.2019 | ||
LU | 12.02.2019 | ||
BE | 28.02.2019 | ||
CH | 28.02.2019 | ||
LI | 28.02.2019 | ||
IS | 07.03.2019 | ||
PT | 07.03.2019 | ||
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SK | 07.11.2018 | ||
SM | 07.11.2018 | ||
BG | 07.02.2019 | ||
NO | 07.02.2019 | ||
GR | 08.02.2019 | ||
IE | 12.02.2019 | ||
LU | 12.02.2019 | ||
BE | 28.02.2019 | ||
CH | 28.02.2019 | ||
LI | 28.02.2019 | ||
IS | 07.03.2019 | ||
PT | 07.03.2019 | ||
Former [2020/09] | AL | 07.11.2018 | |
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NL | 07.11.2018 | ||
PL | 07.11.2018 | ||
RO | 07.11.2018 | ||
RS | 07.11.2018 | ||
SE | 07.11.2018 | ||
SI | 07.11.2018 | ||
SK | 07.11.2018 | ||
SM | 07.11.2018 | ||
BG | 07.02.2019 | ||
NO | 07.02.2019 | ||
GR | 08.02.2019 | ||
IE | 12.02.2019 | ||
LU | 12.02.2019 | ||
CH | 28.02.2019 | ||
LI | 28.02.2019 | ||
IS | 07.03.2019 | ||
PT | 07.03.2019 | ||
Former [2020/04] | AL | 07.11.2018 | |
AT | 07.11.2018 | ||
CZ | 07.11.2018 | ||
DK | 07.11.2018 | ||
EE | 07.11.2018 | ||
FI | 07.11.2018 | ||
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IT | 07.11.2018 | ||
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MC | 07.11.2018 | ||
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PL | 07.11.2018 | ||
RO | 07.11.2018 | ||
RS | 07.11.2018 | ||
SE | 07.11.2018 | ||
SI | 07.11.2018 | ||
SK | 07.11.2018 | ||
SM | 07.11.2018 | ||
BG | 07.02.2019 | ||
NO | 07.02.2019 | ||
GR | 08.02.2019 | ||
LU | 12.02.2019 | ||
CH | 28.02.2019 | ||
LI | 28.02.2019 | ||
IS | 07.03.2019 | ||
PT | 07.03.2019 | ||
Former [2019/50] | AL | 07.11.2018 | |
AT | 07.11.2018 | ||
CZ | 07.11.2018 | ||
DK | 07.11.2018 | ||
EE | 07.11.2018 | ||
FI | 07.11.2018 | ||
HR | 07.11.2018 | ||
IT | 07.11.2018 | ||
LT | 07.11.2018 | ||
LV | 07.11.2018 | ||
MC | 07.11.2018 | ||
NL | 07.11.2018 | ||
PL | 07.11.2018 | ||
RO | 07.11.2018 | ||
RS | 07.11.2018 | ||
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SI | 07.11.2018 | ||
SK | 07.11.2018 | ||
SM | 07.11.2018 | ||
BG | 07.02.2019 | ||
NO | 07.02.2019 | ||
GR | 08.02.2019 | ||
LU | 12.02.2019 | ||
IS | 07.03.2019 | ||
PT | 07.03.2019 | ||
Former [2019/47] | AL | 07.11.2018 | |
AT | 07.11.2018 | ||
CZ | 07.11.2018 | ||
DK | 07.11.2018 | ||
EE | 07.11.2018 | ||
FI | 07.11.2018 | ||
HR | 07.11.2018 | ||
IT | 07.11.2018 | ||
LT | 07.11.2018 | ||
LV | 07.11.2018 | ||
MC | 07.11.2018 | ||
NL | 07.11.2018 | ||
PL | 07.11.2018 | ||
RO | 07.11.2018 | ||
RS | 07.11.2018 | ||
SE | 07.11.2018 | ||
SK | 07.11.2018 | ||
SM | 07.11.2018 | ||
BG | 07.02.2019 | ||
NO | 07.02.2019 | ||
GR | 08.02.2019 | ||
LU | 12.02.2019 | ||
IS | 07.03.2019 | ||
PT | 07.03.2019 | ||
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AT | 07.11.2018 | ||
CZ | 07.11.2018 | ||
DK | 07.11.2018 | ||
EE | 07.11.2018 | ||
FI | 07.11.2018 | ||
HR | 07.11.2018 | ||
IT | 07.11.2018 | ||
LT | 07.11.2018 | ||
LV | 07.11.2018 | ||
MC | 07.11.2018 | ||
NL | 07.11.2018 | ||
PL | 07.11.2018 | ||
RO | 07.11.2018 | ||
RS | 07.11.2018 | ||
SE | 07.11.2018 | ||
SK | 07.11.2018 | ||
SM | 07.11.2018 | ||
BG | 07.02.2019 | ||
NO | 07.02.2019 | ||
GR | 08.02.2019 | ||
IS | 07.03.2019 | ||
PT | 07.03.2019 | ||
Former [2019/40] | AL | 07.11.2018 | |
AT | 07.11.2018 | ||
CZ | 07.11.2018 | ||
DK | 07.11.2018 | ||
EE | 07.11.2018 | ||
FI | 07.11.2018 | ||
HR | 07.11.2018 | ||
IT | 07.11.2018 | ||
LT | 07.11.2018 | ||
LV | 07.11.2018 | ||
NL | 07.11.2018 | ||
PL | 07.11.2018 | ||
RO | 07.11.2018 | ||
RS | 07.11.2018 | ||
SE | 07.11.2018 | ||
SK | 07.11.2018 | ||
SM | 07.11.2018 | ||
BG | 07.02.2019 | ||
NO | 07.02.2019 | ||
GR | 08.02.2019 | ||
IS | 07.03.2019 | ||
PT | 07.03.2019 | ||
Former [2019/37] | AL | 07.11.2018 | |
AT | 07.11.2018 | ||
CZ | 07.11.2018 | ||
DK | 07.11.2018 | ||
EE | 07.11.2018 | ||
FI | 07.11.2018 | ||
HR | 07.11.2018 | ||
IT | 07.11.2018 | ||
LT | 07.11.2018 | ||
LV | 07.11.2018 | ||
NL | 07.11.2018 | ||
PL | 07.11.2018 | ||
RO | 07.11.2018 | ||
RS | 07.11.2018 | ||
SE | 07.11.2018 | ||
SM | 07.11.2018 | ||
BG | 07.02.2019 | ||
NO | 07.02.2019 | ||
GR | 08.02.2019 | ||
IS | 07.03.2019 | ||
PT | 07.03.2019 | ||
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AT | 07.11.2018 | ||
CZ | 07.11.2018 | ||
DK | 07.11.2018 | ||
FI | 07.11.2018 | ||
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IT | 07.11.2018 | ||
LT | 07.11.2018 | ||
LV | 07.11.2018 | ||
NL | 07.11.2018 | ||
PL | 07.11.2018 | ||
RS | 07.11.2018 | ||
SE | 07.11.2018 | ||
BG | 07.02.2019 | ||
NO | 07.02.2019 | ||
GR | 08.02.2019 | ||
IS | 07.03.2019 | ||
PT | 07.03.2019 | ||
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AT | 07.11.2018 | ||
DK | 07.11.2018 | ||
FI | 07.11.2018 | ||
HR | 07.11.2018 | ||
IT | 07.11.2018 | ||
LT | 07.11.2018 | ||
LV | 07.11.2018 | ||
NL | 07.11.2018 | ||
RS | 07.11.2018 | ||
SE | 07.11.2018 | ||
BG | 07.02.2019 | ||
NO | 07.02.2019 | ||
GR | 08.02.2019 | ||
IS | 07.03.2019 | ||
PT | 07.03.2019 | ||
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AT | 07.11.2018 | ||
FI | 07.11.2018 | ||
HR | 07.11.2018 | ||
LT | 07.11.2018 | ||
LV | 07.11.2018 | ||
NL | 07.11.2018 | ||
RS | 07.11.2018 | ||
SE | 07.11.2018 | ||
BG | 07.02.2019 | ||
NO | 07.02.2019 | ||
GR | 08.02.2019 | ||
IS | 07.03.2019 | ||
PT | 07.03.2019 | ||
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HR | 07.11.2018 | ||
LT | 07.11.2018 | ||
LV | 07.11.2018 | ||
NL | 07.11.2018 | ||
RS | 07.11.2018 | ||
SE | 07.11.2018 | ||
BG | 07.02.2019 | ||
NO | 07.02.2019 | ||
GR | 08.02.2019 | ||
IS | 07.03.2019 | ||
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FI | 07.11.2018 | ||
HR | 07.11.2018 | ||
LT | 07.11.2018 | ||
LV | 07.11.2018 | ||
NL | 07.11.2018 | ||
SE | 07.11.2018 | ||
BG | 07.02.2019 | ||
NO | 07.02.2019 | ||
GR | 08.02.2019 | ||
IS | 07.03.2019 | ||
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FI | 07.11.2018 | ||
HR | 07.11.2018 | ||
LT | 07.11.2018 | ||
LV | 07.11.2018 | ||
NL | 07.11.2018 | ||
BG | 07.02.2019 | ||
NO | 07.02.2019 | ||
IS | 07.03.2019 | ||
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LT | 07.11.2018 | ||
BG | 07.02.2019 | ||
NO | 07.02.2019 | ||
IS | 07.03.2019 | ||
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IS | 07.03.2019 | ||
Former [2019/20] | LT | 07.11.2018 | |
NO | 07.02.2019 | Cited in | International search | [A]WO2009105044 (AGENCY SCIENCE TECH & RES [SG], et al) [A] 1-10* abstract *; | [Y]KR20100081003 (SNU R&DB FOUNDATION [KR]) [Y] 4,5 * abstract *; | [Y]WO2011062244 (KURODA MASAHIKO [JP], et al) [Y] 4,5 * abstract *; | [Y]WO2011069100 (UNIV DUKE [US], et al) [Y] 1-10 * page 106; claims 5,11; sequence 950 *; | [Y]WO2011149354 (VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG [NL], et al) [Y] 1-10 * page 64; claim 6; sequence 142 * | by applicant | US5753506 | US5851832 | US6468794 | US6777233 | WO2005121318 | EP1645626 | US7416888 | US7514259 | WO2009105044 | WO2012004611 | - HASSANI; O'REILLY; PEARSE; STROEMER ET AL., PLOS ONE., (2012), vol. 7, no. L 1 | - AMBROS ET AL., RNA, (2003), vol. 9, pages 277 - 279 | - BANERJEE, S.; WILLIAMSON, D.; HABIB, N.; GORDON, M.; CHATAWAY, J., AGE AND AGEING, (2011), vol. 40, pages 7 - 13 | - CHUNG, CELL STEM CELL, (2008), vol. 2, pages 113 - 117 | - DING, D. C.; SHYU, W. C.; LIN S. Z., CELL TRANSPLANT, (2011), vol. 20, pages 5 - 14 | - EINSTEIN, O.; BEN-HUR, T., ARCH NEUROL, (2008), vol. 65, pages 452 - 456 | - HASSANI Z; O'REILLY J; PEARSE Y; STROEMER P; TANG E; SINDEN J; PRICE J; THURET S, "Human neural progenitor cell engraftment increases neurogenesis and microglial recruitment in the brain of rats with stroke", PLOS ONE, (20121121), vol. 7, no. 11, page E50444 | - HODGES ET AL., CELL TRANSPLANT., (2007), vol. 16, no. 2, pages 101 - 15 | - HORIE, N.; PEREIRA, N.P.; NIIZUMA, K.; SUN, G. ET AL., STEM CELLS, (2011), vol. 29, pages 274 - 285 | - KATSUDA; KOSAKA; TAKESHITA; OCHIYA, PROTEOMICS, (2013), vol. 00, pages 1 - 17 | - KATSUDA; TSUCHIYA; KOSAKA; YOSHIOKA; TAKAGAKI; OKI; TAKESHITA; SAKAI; KURODA; OCHIYA, SCIENTIFIC REPORTS, (2013), vol. 3, no. 1197, pages 1 - 11 | - KLIMANSKAYA ET AL., NATURE, (2006), vol. 444, pages 481 - 485 | - KORNBLUM, STROKE, (2007), vol. 38, pages 810 - 816 | - LAI ET AL., "Proteolytic Potential of the MSC Exosome Proteome: Implications for an Exosome-Mediated Delivery of Therapeutic Proteasome", INTERNATIONAL JOURNAL OF PROTEOMICS, (2012), page 14 | - LITTLEWOOD, T. D.; HANCOCK, D. C.; DANIELIAN, P. S. ET AL., NUCLEIC ACID RESEARCH, (1995), vol. 23, pages 1686 - 1690 | - MILJAN, E.A.; SINDEN, J.D., CURRENT OPINION IN MOLECULAR THERAPEUTICS, (2009), vol. 4, pages 394 - 403 | - MILJAN EA; HINES SJ; PANDE P; CORTELING RL; HICKS C; ZBARSKY V; UMACHANDRAN, M; SOWINSKI P; RICHARDSON S; TANG E, "Implantation of c-mycER TAM immortalized human mesencephalic-derived clonal cell lines ameliorates behavior dysfunction in a rat model of Parkinson's disease", STEM CELLS DEV., (200903), vol. 18, no. 2, pages 307 - 19 | - MITCHELL ET AL., JOURNAL OF IMMUNOLOGICAL METHODS, (2008), vol. 335, pages 98 - 105 | - POLLOCK ET AL., EXP NEUROL., (200605), vol. 199, no. 1, pages 143 - 55 | - MARK F PITTENGER; ALASTAIR M MACKAY; STEPHEN C BECK; RAMA K JAISWAL ET AL., SCIENCE, (19990402), vol. 284, page 5411 | - SMITH, E. J.; STROEMER, R.P.; GORENKOVA, N.; NAKAJIMA, M. ET AL., STEM CELLS, (2012), vol. 30, pages 785 - 796 | - STEVENATO, L.; CORTELING, R.; STROEMER, P.; HOPE, A. ET AL., BMC NEUROSCIENCE, (2009), vol. 10, page 86 | - STROEMER, P.; PATEL, S.; HOPE, A.; OLIVEIRA, C.; POLLOCK, K.; SINDEN, J., NEUROREHABIL NEURAL REPAIR, (2009), vol. 23, pages 895 - 909 | - THERY, C.; OSTROWSKI, M.; SEGURA, E. ET AL., NATURE REVIEWS IMMUNOLOGY, (2009), vol. 9, pages 581 - 593 | - TIMMERS, L.; LIM, S. K.; ARSLAN, F.; ARMSTRONG, J. S ET AL., STEM CELL RES, (2007), vol. 1, pages 129 - 137 | - YUAN, S.J.; MARTIN, J; ELIA, J.; FLIPPIN, J. ET AL., PLOS ONE, (2011), vol. 6, page E17540 | Opposition | WO2009105044 | KR20100081003 | WO2011062244 | WO2011069100 | WO2011149354 | - FENG-MEI et al., "Radon-Induced Alterations in Micro-RNA Expression Profiles in Transformed BEAS2B Cells", Journal of Environmental Toxicology Part. A, (20130100), vol. 76, no. 2, XP055628748 DOI: http://dx.doi.org/10.1080/15287394.2013.738176 | - STEVANATO et al., "Investigation of Content, Stoichiometry and Transfer of miRNA from Human Neural Stem Cell Line Derived Exosomes", PLOS One, (20160111), vol. 11, no. 1, page e0146353, XP055628746 DOI: http://dx.doi.org/10.1371/journal.pone.0146353 | - LOTVALL et al., "Cell to Cell Signalling via Exosomes Through es RNA", Cell Adhesion & Migration, (20070700), vol. 1, no. 3, pages 156 - 158, XP002546816 | - VAN BALKOM et al., "Exosomes and the kidney: prospects for diagnosis and therapy of renal diseases", Kidney International, (20110831), vol. 80, no. 11, pages 1138 - 1145, XP055177367 DOI: http://dx.doi.org/10.1038/ki.2011.292 | - THERY et al., "EXOSOMES: COMPOSITION, BIOGENESIS AND FUNCTION", Immunology, (20020800), vol. 2, no. 8, pages 569 - 579, XP001127450 | - "15 Oligonucleotides and 17", Crommelin Daan J. A. et al, Pharmaceutical Biotechnology: fundamentals and Applications. 4th ed., Springer, (20130000), pages 306-314, 318-321, 357-360, 363-364, 368, 370-371, 395 - 399, XP055628744 | - XIN et al., "Exosome-Mediated Transfer of miR-133b from Multipotent Mesenchymal Stromal Cells to Neural Cells Contributes to Neurite Outgrowth", STEM CELLS, (20120718), vol. 30, no. 7, pages 1556 - 1564, XP055073957 DOI: http://dx.doi.org/10.1002/stem.1129 | - FENG-MEI et al., "Radon-Induced Alterations in Micro-RNA Expression Profiles in Transformed BEAS2B Cells", Journal of Environmental Toxicology Part. A, (20130100), vol. 76, no. 2 |