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EP2986599
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EP About this file: EP2986599
| EP2986599 - N-PIPERIDIN-3-YLBENZAMIDE DERIVATIVES FOR TREATING CARDIOVASCULAR DISEASES [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 19.10.2018 Database last updated on 14.06.2024 | |
| Former | Examination is in progress Status updated on 18.11.2016 | Most recent event Tooltip | 19.10.2018 | Application deemed to be withdrawn | published on 21.11.2018 [2018/47] | Applicant(s) | For all designated states Pfizer Inc. 235 East 42nd Street New York, NY 10017 / US | [2016/08] | Inventor(s) | 01 /
DAROUT, Etzer 29 Maple Avenue Apt. 2 Sharon, MA 02067 / US | 02 /
DULLEA, Robert 63 Fairway Drive Groton, Massachusetts 01450 / US | 03 /
HAWKINS, Julie Jia Li 1 Grey Fox Lane Weston, Connecticut 06883 / US | 04 /
LONDREGAN, Allyn T. 26 Chapel Road Barrington, Rhode Island 02806 / US | 05 /
LORIA, Paula M. 13 Town Clerk Rd Killingworth, Connecticut 06419 / US | 06 /
MAGUIRE, Bruce 17 Waterhouse Lane Chester, Connecticut 06412 / US | 07 /
MCCLURE, Kim F. 12 Willow Drive Mystic, Connecticut 06355 / US | 08 /
PETERSEN, Donna N. 107 Forsyth Road Salem, Connecticut 06420 / US | 09 /
PIOTROWSKI, David W. 19 Beacon Hill Drive Waterford, Connecticut 06385 / US | [2016/22] |
| Former [2016/14] | 01 /
DAROUT, Etzer 29 Maple Avenue Apt. 2 Sharon, MA 02067 / US | ||
| 02 /
DULLEA, Robert 63 Fairway Drive Groton, Massachusetts 01450 / US | |||
| 03 /
HAWKINS, Julie Jia Li 1 Grey Fox Lane Weston, Connecticut 06883 / US | |||
| 04 /
LONDREGAN, Allyn T. 26 Chapel Road Barrington, Rhode Island 02806 / US | |||
| 05 /
LORIA, Paula M. 38 River Road Killingworth, Connecticut 06419 / US | |||
| 06 /
MAGUIRE, Bruce 17 Waterhouse Lane Chester, Connecticut 06412 / US | |||
| 07 /
MCCLURE, Kim F. 12 Willow Drive Mystic, Connecticut 06355 / US | |||
| 08 /
PETERSEN, Donna N. 107 Forsyth Road Salem, Connecticut 06420 / US | |||
| 09 /
PIOTROWSKI, David W. 19 Beacon Hill Drive Waterford, Connecticut 06385 / US | |||
| Former [2016/08] | 01 /
DAROUT, Etzer 700 Huron Avenue Apt. 2H Cambridge, Massachusetts 02138 / US | ||
| 02 /
DULLEA, Robert 63 Fairway Drive Groton, Massachusetts 01450 / US | |||
| 03 /
HAWKINS, Julie Jia Li 1 Grey Fox Lane Weston, Connecticut 06883 / US | |||
| 04 /
LONDREGAN, Allyn T. 26 Chapel Road Barrington, Rhode Island 02806 / US | |||
| 05 /
LORIA, Paula M. 38 River Road Killingworth, Connecticut 06419 / US | |||
| 06 /
MAGUIRE, Bruce 17 Waterhouse Lane Chester, Connecticut 06412 / US | |||
| 07 /
MCCLURE, Kim F. 12 Willow Drive Mystic, Connecticut 06355 / US | |||
| 08 /
PETERSEN, Donna N. 107 Forsyth Road Salem, Connecticut 06420 / US | |||
| 09 /
PIOTROWSKI, David W. 19 Beacon Hill Drive Waterford, Connecticut 06385 / US | Representative(s) | Pfizer European Patent Department 23-25 avenue du Docteur Lannelongue 75668 Paris Cedex 14 / FR | [2016/08] | Application number, filing date | 14718777.7 | 03.04.2014 | [2016/08] | WO2014IB60407 | Priority number, date | US201361812864P | 17.04.2013 Original published format: US 201361812864 P | US201361880336P | 20.09.2013 Original published format: US 201361880336 P | US201361898667P | 01.11.2013 Original published format: US 201361898667 P | [2016/08] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2014170786 | Date: | 23.10.2014 | Language: | EN | [2014/43] | Type: | A1 Application with search report | No.: | EP2986599 | Date: | 24.02.2016 | Language: | EN | The application published by WIPO in one of the EPO official languages on 23.10.2014 takes the place of the publication of the European patent application. | [2016/08] | Search report(s) | International search report - published on: | EP | 23.10.2014 | Classification | IPC: | C07D401/14, C07D413/14, A61K31/4725, A61K31/519, C07D471/04, C07D487/04, A61P7/00 | [2016/08] | CPC: |
C07D401/14 (EP,RU,US);
A61K31/519 (RU,US);
A61K31/4545 (EP,RU,US);
A61K31/4725 (EP,RU,US);
A61K45/06 (US);
A61P13/12 (EP);
A61P25/28 (EP);
A61P27/02 (EP);
A61P29/00 (EP);
A61P3/00 (EP);
A61P3/06 (EP);
A61P3/10 (EP);
A61P43/00 (EP);
A61P7/00 (EP);
A61P7/02 (EP);
A61P9/00 (EP);
A61P9/04 (EP);
A61P9/10 (EP);
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2016/08] | Title | German: | N-PIPERIDIN-3-YLBENZAMID-DERIVATE ZUR BEHANDLUNG VON HERZ-KREISLAUF-ERKRANKUNGEN | [2016/08] | English: | N-PIPERIDIN-3-YLBENZAMIDE DERIVATIVES FOR TREATING CARDIOVASCULAR DISEASES | [2016/08] | French: | DÉRIVÉS DE N-PIPÉRIDIN-3-YLBENZAMIDE DANS LE TRAITEMENT DES MALADIES CARDIOVASCULAIRES | [2016/08] | Entry into regional phase | 17.11.2015 | National basic fee paid | 17.11.2015 | Designation fee(s) paid | 17.11.2015 | Examination fee paid | Examination procedure | 28.09.2015 | Amendment by applicant (claims and/or description) | 17.11.2015 | Examination requested [2016/08] | 18.11.2016 | Despatch of a communication from the examining division (Time limit: M06) | 17.05.2017 | Reply to a communication from the examining division | 09.02.2018 | Despatch of a communication from the examining division (Time limit: M04) | 20.06.2018 | Application deemed to be withdrawn, date of legal effect [2018/47] | 13.07.2018 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2018/47] | Fees paid | Renewal fee | 02.05.2016 | Renewal fee patent year 03 | 02.05.2017 | Renewal fee patent year 04 | Penalty fee | Additional fee for renewal fee | 30.04.2018 | 05 M06 Not yet paid |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Cited in | International search | [A]WO2009072649 (DAINIPPON SUMITOMO PHARMA CO [JP], et al) [A] 1-44 * Formula (I);; example 58; claim - *; | [XA]WO2011051961 (CADILA HEALTHCARE LTD [IN], et al) [X] 22-34 * example -; claim - * [A] 1-21,35-44; | [X] - SEIDAH NABIL G, "PCSK9 as a therapeutic target of dyslipidemia", EXPERT OPINION ON THERAPEUTIC TARGETS, ASHLEY PUBLICATIONS, LONDON, GB, (20090101), vol. 13, no. 1, doi:10.1517/14728220802600715, ISSN 1472-8222, pages 19 - 28, XP008101389 [X] 22-34 * Paragraph 2.1 * DOI: http://dx.doi.org/10.1517/14728220802600715 | by applicant | HU151865 | CZ128471 | SE168308 | DD55956 | BE639386 | JPS485585B | US2161938 | US2357985 | US2500444 | AT168063B | DE860217 | US2661372 | US2661373 | DE905738 | FR1103113 | GB740932 | US2769015 | US2783241 | GB769757 | US2809194 | US2816118 | GB795174 | GB803372 | SU115905 | GB807826 | US2882271 | GB824547 | US2937169 | BE587225 | GB851287 | GB856409 | US2965655 | US2965656 | US2970082 | GB861367 | GB862248 | US2976289 | DE1102973 | DE1102750 | US2980699 | US2980679 | US3009911 | US3010965 | US3012042 | GB885078 | US3055904 | US3056836 | US3058882 | GB909357 | BE620829 | US3072653 | CH366523 | US3081230 | US3108097 | US3119826 | FR1365504 | US3152173 | FR2790M | US3160641 | US3164588 | FR1390056 | GB984810 | US3183243 | US3188329 | US3228943 | FR1460571 | GB1025578 | US3254076 | US3255241 | US3261859 | US3262977 | US3262852 | US3265573 | US3267104 | US3267103 | NL6605692 | US3282938 | US3299067 | US3309406 | US3334096 | GB1077603 | US3337628 | US3338899 | US3350400 | US3355463 | US3356692 | US3360518 | US3371014 | DE1265758 | US3384642 | US3399192 | US3408387 | US3422107 | CH469002 | US3432545 | CH472404 | US3459756 | GB1160925 | BE730345 | DE1910481 | US3485847 | US3501769 | US3509164 | US3511836 | US3520919 | US3527761 | US3532685 | DE2020464 | US3542870 | US3551493 | US3563997 | US3565911 | US3567777 | US3634583 | US3655663 | US3663607 | US3663570 | US3663597 | US3665002 | US3669968 | DE2213044 | US3723476 | US3758506 | US3770724 | US3773939 | DE2240599 | US3799934 | US3818021 | US3819702 | US3836671 | DE2334404 | US3850941 | US3853923 | US3857952 | US3857981 | US3870720 | US3873600 | US3895030 | US3910924 | US3929836 | US3932400 | US3935267 | US3935259 | US3940489 | DE2521113 | US3961071 | US3960891 | US3962238 | US3983140 | US3985758 | US3997666 | US4010273 | US4012444 | US4018824 | US4018890 | US4018929 | US4034009 | US4035750 | US4038313 | US4045482 | US4046889 | US4059622 | US4062950 | DE2728641 | US4105776 | US4129565 | US4146643 | US4154839 | US4171370 | US4174439 | US4188390 | US4189438 | US4217305 | US4217307 | US4220649 | US4231938 | US4242453 | US4248883 | US4252984 | US4252825 | US4252721 | US4254256 | USRE30577E | US4264611 | US4273765 | EP0041491 | US4337201 | US4338322 | US4340541 | US4344949 | US4346227 | BE893553 | US4374829 | US4385051 | US4394382 | US4405644 | US4410520 | US4444784 | EP0106275 | US4448784 | US4450171 | US4451455 | US4452813 | US4452790 | US4452811 | US4463176 | US4466972 | US4470972 | US4503067 | US4508727 | US4508729 | US4555502 | US4567175 | US4572909 | US4587258 | US4598089 | US4623714 | US4634765 | US4639436 | US4654362 | US4663325 | US4672068 | US4678783 | US4692464 | US4699905 | US4701559 | US4703063 | US4705797 | US4739073 | US4786635 | US4801599 | US4804770 | US4808605 | US4847271 | US4879303 | US4885284 | US4892875 | EP0363934 | US4933361 | US4952592 | EP0395768 | US5011930 | US5011859 | US5026554 | US5041432 | US5051534 | US5064856 | US5064864 | US5084461 | EP0468434 | US5091524 | US5102915 | US5120729 | EP0491226 | US5138069 | US5157116 | US5185351 | US5192772 | US5196444 | WO9312069 | US5270317 | US5273995 | US5274143 | WO9400480 | US5278171 | WO9401404 | FR2697250 | WO9410150 | EP0304063 | US5391571 | US5399578 | US5420305 | US5502199 | US5504078 | WO9610559 | US5510379 | US5512548 | US5512565 | JPH08143457 | US5540917 | WO9626948 | EP0738510 | WO9639384 | WO9639385 | WO9640640 | US5602151 | US5643874 | US5728704 | WO9823593 | US5866578 | US6140343 | US6197786 | USRE37314E | WO02064549 | WO02064130 | US6579879 | US2003225158 | US6723752 | - HALEBLIAN, J PHARM SCI, (197508), vol. 64, no. 8, pages 1269 - 1288 | - LOUIS F. FIESER; MARY FIESER, Reagents for Organic Synthesis, WILEY, vol. 1-19 | - Beilsteins Handbuch der organischen Chemie, 4, Aufl., SPRINGER-VERLAG, vol. 4 | - LOPEZ-RODRIGUEZ; MARIA L., BIOORG. MED. CHEM., (2004), vol. 12, pages 5181 - 5184 | - BILODEAU, MARK T. ET AL., ORG. LETT., (2002), pages 3127 - 3129 | - LONDREGAN, ALLYN ET AL., ORG. LETT., (2011), pages 1840 - 1843 | - LAUDER ET AL., J. AM. CHEM. SOC., vol. 39, pages 659 - 68 | - ST. MAURICE ET AL., BIOCHEM., vol. 43, pages 2524 - 2532 | - LOPEZ-RODRIGUEZ; MARIA L. ET AL., BIOORG. MED. CHEM., (2004), vol. 12, pages 5181 - 5184 | - ROH ET AL., EUR. J. ORG. CHEM., (2012), pages 6101 - 6118 | - CHARTON, J. ET AL., TETRAHEDRON LETT., (2007), pages 1479 - 1483 | - METH. ENZYMOL., (1981), vol. 71, pages 455 - 509 | - METH ENZYMOL., (1975), vol. 35, pages 155 - 160 | - METH. ENZYMOL., (1985), vol. 110, pages 19 - 26 | - METH. ENZYMOL., (1985), vol. 110, pages 9 - 19 | - E.I. MERCER, PROG.LIP. RES., (1993), vol. 32, pages 357 - 416 | - J. ANTIBIOT., (1996), vol. 49, no. 8, pages 815 - 816 | - BIOORG. MED. CHEM. LETT., (1996), vol. 6, pages 1951 - 1954 | - WETTERAU, J. R., SCIENCE, (1992), vol. 258, page 999 | - METH. ENZYMOL., (1969), vol. 15, pages 393 - 454 | - METH. ENZYMOL., (1985), vol. 110, pages 359 - 373 | - CURR. OP. THER. PATENTS, (1993), pages 861 - 4 | - BIOCHIM. BIOPHYS. ACTA, (1984), vol. 794, pages 466 - 471 | - FEBS LETT., (1989), vol. 244, pages 347 - 350 | - J. LIPID RES., (1993), vol. 34, pages 377 - 395 | - HEIDER ET AL., JOURNAL OF LIPID RESEARCH., (1983), vol. 24, page 1127 | - METHODS ENZYMOL., vol. 286, pages 190 - 231 | - C.K. ABRAMS ET AL., GASTROENTEROLOGY, (1987), vol. 92, page 125 | - PETERSEN ET AL., LIEBIG'S ANNALEN, (1949), vol. 562, pages 205 - 229 | - KITAHARA ET AL., J. ANTIBIOTICS, (1987), vol. 40, no. 11, pages 1647 - 1650 | - UMEZAWA ET AL., J. ANTIBIOTICS, (1980), vol. 33, pages 1594 - 1596 | - J. MED. CHEM., (1998), vol. 41, pages 2934 - 2938 | - J. MALONE, DIABETES, (1980), vol. 29, pages 861 - 864 | - ANALYT. BIOCHEM, (2000), vol. 280, pages 329 - 331 | - BIOCHEMISTRY, (1969), vol. 8, page 4214 | - METHODS ENZYMOL., (1955), vol. 1, page 149 | - CLIFTON ET AL., JOURNAL OF MEDICINAL CHEMISTRY, (1982), vol. 25, page 670 | - SEEMAN ET AL., HELV. CHIM. ACTA, (1971), vol. 54, page 241 | - ULOTH ET AL., JOURNAL OF MEDICINAL CHEMISTRY, (1966), vol. 9, page 88 | - KENNEDY ET AL., JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, (1955), vol. 77, page 250 | - KENNEDY, JOURNAL OF BIOLOGICAL CHEMISTRY, (1956), vol. 222, page 185 | - HERMANN ET AL., JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, (1979), vol. 101, page 1540 | - BLICKE ET AL., JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, (1942), vol. 64, page 1722 | - GOLDBERG, CHEM. PROD. CHEM. NEWS, (1954), vol. 17, page 371 | - J. CHEM. SOC., (1958), page 2426 | - BAXTER ET AL., JOURNAL OF THE CHEMICAL SOCIETY, (1949), page 30 | - CORRIGAN ET AL., JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, (1945), vol. 67, page 1894 | - WALTER ET AL., JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, (1941), vol. 63, page 2771 | - HAMBURG ET AL., ARCH. BIOCHEM. BIOPHYS., (1958), vol. 76, page 252 | - BADGETT ET AL., JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, (1947), vol. 69, page 2907 | - BIOCHEM. BIOPHYS. RES. COMMUN., (1961), vol. 6, page 210 | - BUDAVERI,, Merck Index, Twelfth Edition,, (1996), page 1353 | - KORBONITS ET AL., ACTA. PHARM. HUNG., (1968), vol. 38, page 98 | - TSCHITSCHIBABIN, ANNALEN, (1930), vol. 479, page 303 | - FREUDENBERG ET AL., BER, (1957), vol. 90, page 957 | - MCMANUS ET AL., "136th Am. Soc. Meeting (Atlantic City", ABSTRACT OF PAPERS, (195909), pages 13 - 0 | - CLOSE ET AL., JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, (1960), vol. 82, page 1132 | - DESTEVENS ET AL., EXPERIENTIA, (1960), vol. 16, page 113 | - OLIVIER, REC. TRAV. CHIM., (1918), vol. 37, page 307 | - ARTERIOSCLER THROMB VASC BIOL, (2012), vol. 32, pages 1585 - 1595 | - "Cell-Free Protein Synthesis Systems with Extracts from Cultured Human Cells", S. MIKAMI; T. KOBAYASHI; H. IMATAKA ET AL., Methods in Molecular Biology, HUMANA PRESS, (2010), vol. 607, pages 43 - 52 | - CHEN ET AL., J PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, (2001), vol. 26, page 63 | US20030720942 | US20040552114 | US20040807838 |