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Extract from the Register of European Patents

EP About this file: EP3013814

EP3013814 - SUBSTITUTED TETRAHYDROCARBAZOLE AND CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  20.04.2018
Database last updated on 17.05.2024
FormerThe patent has been granted
Status updated on  12.05.2017
FormerGrant of patent is intended
Status updated on  10.05.2017
FormerRequest for examination was made
Status updated on  05.04.2017
FormerGrant of patent is intended
Status updated on  21.11.2016
Most recent event   Tooltip20.04.2018No opposition filed within time limitpublished on 23.05.2018  [2018/21]
Applicant(s)For all designated states
Bristol-Myers Squibb Company
Route 206 and Province Line Road
Princeton, NJ 08543 / US
[2016/18]
Inventor(s)01 / TINO, Joseph A.
c/o Bristol-Myers Squibb Company
Route 206 & Province Line Road
Princeton, New Jersey 08543 / US
02 / SRIVASTAVA, Anurag S.
c/o Bristol-Myers Squibb Company
Route 206 & Province Line Road
Princeton, New Jersey 08543 / US
03 / KO, Soo Sung
7 Aston Circle
Hockessin, Delaware 19707 / US
04 / GALELLA, Michael A.
c/o Bristol-Myers Squibb Company
Route 206 & Province Line Road
Princeton, New Jersey 08543 / US
05 / LANGEVINE, Charles M.
580 Flatbush Avenue, 1M
Brooklyn, New York 11225 / US
06 / DELUCCA, George V.
c/o Bristol-Myers Squibb Company
Route 206 & Province Line Road
Princeton, New Jersey 08543 / US
07 / LIU, Qingjie
c/o Bristol-Myers Squibb Company
Route 206 & Province Line Road
Princeton, New Jersey 08543 / US
08 / BATT, Douglas G.
c/o Bristol-Myers Squibb Company
Route 206 & Province Line Road
Princeton, New Jersey 08543 / US
09 / WATTERSON, Scott Hunter
c/o Bristol-Myers Squibb Company
Route 206 & Province Line Road
Princeton, New Jersey 08543 / US
10 / SHI, Qing
c/o Bristol-Myers Squibb Company
Route 206 & Province Line Road
Princeton, New Jersey 08543 / US
11 / BERTRAND, Myra Beaudoin
c/o Bristol-Myers Squibb Company
Route 206 & Province Line Road
Princeton, New Jersey 08543 / US
 [2017/24]
Former [2016/18]01 / TINO, Joseph A.
c/o Bristol-Myers Squibb Company
Route 206 & Province Line Road
Princeton, New Jersey 08543 / US
02 / SRIVASTAVA, Anurag S.
c/o Bristol-Myers Squibb Company
Route 206 & Province Line Road
Princeton, New Jersey 08543 / US
03 / KO, Soo Sung
7 Aston Circle
Hockessin, Delaware 19707 / US
04 / GALELLA, Michael A.
c/o Bristol-Myers Squibb Company
Route 206 & Province Line Road
Princeton, New Jersey 08543 / US
05 / LANGEVINE, Charles M.
580 Flatbush Avenue, 1M
Brooklyn, New York 11225 / US
06 / DELUCCA, George V.
c/o Bristol-Myers Squibb Company
Route 206 & Province Line Road
Princeton, New Jersey 08543 / US
07 / LIU, Qingjie
c/o Bristol-Myers Squibb Company
Route 206 & Province Line Road
Princeton, New Jersey 08543 / US
08 / BATT, Douglas G.
c/o Bristol-Myers Squibb Company
Route 206 & Province Line Road
Princeton, New Jersey 08543 / US
09 / WATTERSON, Scott Hunter
c/o Bristol-Myers Squibb Company
Route 206&Province Line Road
Princeton
New Jersey 08543 / US
10 / SHI, Qing
c/o Bristol-Myers Squibb Company
Route 206 & Province Line Road
Princeton, New Jersey 08543 / US
11 / BERTRAND, Myra Beaudoin
c/o Bristol-Myers Squibb Company
Route 206 & Province Line Road
Princeton, New Jersey 08543 / US
Representative(s)Beacham, Annabel Rose
Dehns
St Bride's House
10 Salisbury Square
London EC4Y 8JD / GB
[2016/18]
Application number, filing date14740094.925.06.2014
[2016/18]
WO2014US43978
Priority number, dateUS201361839141P25.06.2013         Original published format: US 201361839141 P
[2016/18]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2014210085
Date:31.12.2014
Language:EN
[2014/53]
Type: A1 Application with search report 
No.:EP3013814
Date:04.05.2016
Language:EN
The application published by WIPO in one of the EPO official languages on 31.12.2014 takes the place of the publication of the European patent application.
[2016/18]
Type: B1 Patent specification 
No.:EP3013814
Date:14.06.2017
Language:EN
[2017/24]
Search report(s)International search report - published on:EP31.12.2014
ClassificationIPC:C07D403/10, C07D471/04, C07D513/04, A61K31/429, A61K31/513, A61K31/517, A61K31/522, A61P37/00, A61P29/00
[2016/18]
CPC:
C07D513/04 (EP,US); A61K31/517 (US); A61P19/02 (EP);
A61P25/28 (EP); A61P29/00 (EP); A61P35/00 (EP);
A61P37/00 (EP); A61P37/02 (EP); A61P37/06 (EP);
A61P43/00 (EP); C07D209/88 (EP,US); C07D239/70 (EP,US);
C07D403/10 (EP,US); C07D471/04 (EP,US); C07B2200/07 (EP,US);
C07B2200/13 (EP,US) (-)
C-Set:
C07D209/88, C07B2200/07 (US);
C07D209/88, C07B2200/13 (US);
C07D239/70, C07B2200/07 (US);
C07D239/70, C07B2200/13 (US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/18]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:ALS KINASEHEMMER GEEIGNETE SUBSTITUIERTE TETRAHYDROCARBAZOL- UND CARBAZOL-CARBOXAMID-VERBINDUNGEN[2016/18]
English:SUBSTITUTED TETRAHYDROCARBAZOLE AND CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS[2016/18]
French:COMPOSÉS CARBOXAMIDE DE CARBAZOLE ET DE TÉTRAHYDROCARBAZOLE SUBSTITUÉS CONVENANT COMME INHIBITEURS DE KINASES[2016/18]
Entry into regional phase20.01.2016National basic fee paid 
20.01.2016Designation fee(s) paid 
20.01.2016Examination fee paid 
Examination procedure20.01.2016Examination requested  [2016/18]
18.08.2016Amendment by applicant (claims and/or description)
22.11.2016Communication of intention to grant the patent
31.03.2017Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
31.03.2017Fee for grant paid
31.03.2017Fee for publishing/printing paid
09.05.2017Information about intention to grant a patent
09.05.2017Receipt of the translation of the claim(s)
Opposition(s)15.03.2018No opposition filed within time limit [2018/21]
Fees paidRenewal fee
10.06.2016Renewal fee patent year 03
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Cited inInternational search[A]WO2011159857  (BRISTOL MYERS SQUIBB CO [US], et al) [A] 1-13 * example - *;
 [A]US8084620  (LIU QINGJIE [US], et al) [A] 1-13 * example - *;
 [A]  - YAN LOU ET AL, "Bruton's Tyrosine Kinase Inhibitors: Approaches to Potent and Selective Inhibition, Preclinical and Clinical Evaluation for Inflammatory Diseases and B Cell Malignancies", JOURNAL OF MEDICINAL CHEMISTRY, (20120524), vol. 55, no. 10, doi:10.1021/jm300035p, ISSN 0022-2623, pages 4539 - 4550, XP055080230 [A] 1-13 * example - *

DOI:   http://dx.doi.org/10.1021/jm300035p
by applicantUS4200750
 WO2011159857
 US8084620
 US8242260
    - LAPLANTE ET AL., J. MED. CHEM., (2011), vol. 54, pages 7005 - 7022
    - WHITE ET AL., J. CHROMATOGRAPHY A, (2005), vol. 1074, pages 175 - 185
    - "Design and Application of Prodrugs", BUNDGAARD, H. ET AL., A Textbook of Drug Design and Development, HARWOOD ACADEMIC PUBLISHERS, (1991), pages 113 - 191
    - CHOU ET AL., ADV. ENZYME REGUL., (1984), vol. 22, pages 27 - 55
    - HERAVI, M.M. ET AL., TETRAHEDRON, (2012), vol. 68, page 9145
    - ISHIYAMA, T. ET AL., TETRAHEDRON, (2001), vol. 57, page 9813
    - CAO, J. ET AL., SYNTHETIC COMMUN., (2009), vol. 39, page 205
    - WU, F. ET AL., J. ORG. CHEM., (2004), vol. 69, page 9307
    - JACOBSEN, M.F. ET AL., J. ORG. CHEM., (2006), vol. 71, page 9183
    - HIRSCH, J. ET AL., J. ORG. CHEM., (1986), vol. 51, page 2218
    - KAMATA, J. ET AL., CHEM. PHARM. BULL., (2004), vol. 52, page 1071
    - STILL, W.C. ET AL., J. ORG. CHEM., (1978), vol. 43, page 2923
    - COSIER, J. ET AL., J. APPL. CRYST., (1986), vol. 19, page 105
    - PARDANANI, A, LEUKEMIA, (2012), vol. 26, pages 1449 - 1451
    - UETRECHT, CHEM. RES. TOXICOL., (1999), vol. 12, pages 387 - 395
    - NAKAYAMA, DRUG METABOLISM AND DISPOSITION, (2009), vol. 37, no. 9, pages 1970 - 1977
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.