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Extract from the Register of European Patents

EP About this file: EP2957910

EP2957910 - USE OF IGF-1 AS A REAGENT FOR EARLY DIAGNOSIS AND/OR PROGNOSIS OF ALZHEIMER DISEASE [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  01.09.2017
Database last updated on 19.10.2024
FormerRequest for examination was made
Status updated on  20.04.2017
Most recent event   Tooltip01.09.2017Application deemed to be withdrawnpublished on 04.10.2017  [2017/40]
Applicant(s)For all designated states
Consejo Superior De Investigaciones Científicas (CSIC)
Serrano 117
28006 Madrid / ES
For all designated states
Universidad Autónoma De Madrid (UAM)
Ciudad Universitaria de Cantoblanco C/ Einstein 3
28049 Madrid / ES
[N/P]
Former [2015/52]For all designated states
Consejo Superior De Investigaciones Científicas (CSIC)
Serrano 117
28006 Madrid / ES
For all designated states
Universidad Autónoma De Madrid (UAM)
Ciudad Universitaria de Cantoblanco C/ Einstein 3
28049 Madrid / ES
Inventor(s)01 / TRUEBA SAIZ, Angel
Consejo Superior De Investigaciones Científicas
(CSIC)
C/ Serrano 117
28006 Madrid / ES
02 / TORRES ALEMAN, Ignacio
Consejo Superior De Investigaciones Científicas
(CSIC)
C/ Serrano 117
28006 Madrid / ES
03 / CAVADA MARTINEZ, Carmen
Universidad Autónoma De Madrid
Ciudad Universitaria de
Cantoblanco
C/ Einstein 3
28049 Madrid / ES
04 / NUÑEZ MOLINA, Angel
Universidad Autónoma De Madrid
Ciudad Universitaria de
Cantoblanco
C/ Einstein 3
28049 Madrid / ES
 [2015/52]
Representative(s)Pons
Glorieta Rubén Darío 4
28010 Madrid / ES
[N/P]
Former [2015/52]Pons Ariño, Angel
Pons Patentes y Marcas Internacional, S.L.
Glorieta Rubén Dario 4
28010 Madrid / ES
Application number, filing date14751079.612.02.2014
[2015/52]
WO2014ES70103
Priority number, dateES2013003018713.02.2013         Original published format: ES 201330187
[2015/52]
Filing languageES
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2014125150
Date:21.08.2014
Language:ES
[2014/34]
Type: A1 Application with search report 
No.:EP2957910
Date:23.12.2015
Language:EN
[2015/52]
Search report(s)International search report - published on:ES21.08.2014
(Supplementary) European search report - dispatched on:EP16.08.2016
ClassificationIPC:A61K38/30, A61K31/5513, G01N33/53, G01N33/68
[2016/37]
CPC:
A61K38/30 (EP,US); A61K49/0004 (US); A61B5/372 (US);
A61B5/384 (US); A61K31/5513 (EP,US); A61K45/06 (EP,US);
G01N33/6896 (EP,US); A61B2503/40 (EP); A61B2503/42 (EP);
A61B5/369 (EP); A61B5/4088 (EP); A61B5/4842 (EP);
A61B5/4848 (EP); G01N2333/475 (EP,US); G01N2800/2821 (EP,US) (-)
C-Set:
A61K31/5513, A61K2300/00 (US,EP);
A61K38/30, A61K2300/00 (EP,US)
Former IPC [2015/52]G01N33/53, A61K38/30
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2015/52]
TitleGerman:VERWENDUNG VON IGF-1 ALS REAGENZ ZUR FRÜHDIAGNOSE UND/ODER PROGNOSE DER ALZHEIMER-KRANKHEIT[2015/52]
English:USE OF IGF-1 AS A REAGENT FOR EARLY DIAGNOSIS AND/OR PROGNOSIS OF ALZHEIMER DISEASE[2015/52]
French:UTILISATION D'IGF-1 COMME RÉACTIF DE DIAGNOSTIC ET/OU PRONOSTIC PRÉCOCE DE LA MALADIE D'ALZHEIMER[2015/52]
Entry into regional phase09.09.2015Translation filed 
09.09.2015National basic fee paid 
09.09.2015Search fee paid 
09.09.2015Designation fee(s) paid 
09.09.2015Examination fee paid 
Examination procedure09.09.2015Examination requested  [2015/52]
14.03.2017Application deemed to be withdrawn, date of legal effect  [2017/40]
21.04.2017Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2017/40]
Fees paidRenewal fee
05.02.2016Renewal fee patent year 03
Penalty fee
Additional fee for renewal fee
28.02.201704   M06   Not yet paid
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[A]WO2008095261  (POWMRI LTD [AU], et al) [A] 1-14 * page 4, line 12 - line 20; claim - *;
 [XY]WO2008153929  (MASSACHUSETTS INST TECHNOLOGY [US], et al) [X] 7,8,10 * claims 1, 5, 20 * [Y] 7-13;
 [XY]US2009130216  (CARTT STEVE [US], et al) [X] 7,8,10,11 * paragraph [0135] * [Y] 7-13;
 [A]  - SCHUBIGER P A ET AL, "EVALUATION OF A MULTICENTER STUDY WITH IOMAZENIL A BENZODIAZEPINE RECEPTOR LIGAND", NUCLEAR MEDICINE COMMUNICATIONS, (1991), vol. 12, no. 7, ISSN 0143-3636, pages 569 - 582, XP009191099 [A] 1-14 * abstract *
 [XPI]  - TRUEBA-SÁIZ A ET AL, "Loss of serum IGF-I input to the brain as an early biomarker of disease onset in Alzheimer mice.", TRANSLATIONAL PSYCHIATRY 2013, (2013), vol. 3, ISSN 2158-3188, page e330, XP055290973 [XP] 1-6 * the whole document * [I] 1-14

DOI:   http://dx.doi.org/10.1038/tp.2013.102
International search[A]US5017470  (AROONSAKUL CHAOVANEE [US]);
 [A]WO2006060753  (RHODE ISLAND HOSPITAL [US], et al);
 [A]  - VARDY EMMA R L C ET AL., "Increased circulating insulin-like growth factor-1 in late-onset Alzheimer's disease..", JOURNAL OF ALZHEIMER&APOS DISEASE, JAD NETHERLANDS, (20071130), vol. 12, no. 4, pages 285 - 290, XP055273600
    [ ] - PUBMED
 [A]  - THAM A ET AL., "Insulin-like growth factors and insulin-like growth factor binding proteins in cerebrospinal fluid and serum of patients with dementia of the Alzheimer type..", JOURNAL OF NEURAL TRANSMISSION. PARKINSON'S DISEASE AND DEMENTIA SECTION AUSTRIA, (19921130), vol. 5, no. 3, pages 165 - 176, XP008123476
 [A]  - SALEHI ZIVAR ET AL., "Insulin like growth factor-1 and insulin like growth factor binding proteins in the cerebrospinal fluid and serum from patients with Alzheimer's disease..", BIOFACTORS, OXFORD , ENGLAND) NETHERLANDS, (20071130), vol. 33, no. 2, pages 99 - 106, XP055273638

DOI:   http://dx.doi.org/10.1002/biof.5520330202
by applicantEP0792458
 ES2259270
 EP1385531
 EP1509621
    - SELKOE, D.J., NEURON, (2001), vol. 32, pages 177 - 180
    - BLUM-DEGEN, D. ET AL., J. NEURAL TRANSM., (1995), pages 139 - 147
    - CARRO, E.; TORRES-AIEMAN, I., J PHARMACOL., (2004), vol. 490, pages 127 - 133
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.