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Extract from the Register of European Patents

EP About this file: EP2986113

EP2986113 - COMPOSITIONS AND METHODS FOR THE TREATMENT OF BRAIN INJURY [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  02.07.2021
Database last updated on 20.05.2024
FormerThe patent has been granted
Status updated on  24.07.2020
FormerGrant of patent is intended
Status updated on  17.03.2020
FormerExamination is in progress
Status updated on  11.01.2019
Most recent event   Tooltip27.04.2024Lapse of the patent in a contracting state
New state(s): MK		published on 29.05.2024 [2024/22]
Applicant(s)For all designated states
The Children's Hospital of Philadelphia
3401 Civic Center Boulevard
Philadelphia, PA 19104 / US
[2017/50]
Former [2016/08]For all designated states
The Children's Hospital of Philadelphia
34th Street & Civic Center Boulevard
Philadelphia, PA 19104 / US
Inventor(s)01 / COHEN, Akiva, S.
115 Maple Avenue
Bala Cynwyd, PA 19004 / US
 [2016/08]
Representative(s)Potter Clarkson
Chapel Quarter
Mount Street
Nottingham NG1 6HQ / GB
[N/P]
Former [2020/35]Potter Clarkson
The Belgrave Centre
Talbot Street
Nottingham NG1 5GG / GB
Former [2016/08]Potter Clarkson LLP
The Belgrave Centre
Talbot Street
Nottingham NG1 5GG / GB
Application number, filing date14785796.515.04.2014
[2016/08]
WO2014US34142
Priority number, dateUS201361812352P16.04.2013         Original published format: US 201361812352 P
US201361883526P27.09.2013         Original published format: US 201361883526 P
[2016/08]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2014172341
Date:23.10.2014
Language:EN
[2014/43]
Type: A1 Application with search report 
No.:EP2986113
Date:24.02.2016
Language:EN
The application published by WIPO in one of the EPO official languages on 23.10.2014 takes the place of the publication of the European patent application.
[2016/08]
Type: B1 Patent specification 
No.:EP2986113
Date:26.08.2020
Language:EN
[2020/35]
Search report(s)International search report - published on:US23.10.2014
(Supplementary) European search report - dispatched on:EP19.12.2016
ClassificationIPC:A61K31/195
[2020/16]
CPC:
A61K31/198 (EP,US); A61K9/0053 (US); A61P25/00 (EP)
Former IPC [2017/03]A01N37/12, A61P25/00
Former IPC [2016/08]A01N37/12
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/08]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:ZUSAMMENSETZUNGEN UND VERFAHREN ZUR BEHANDLUNG VON GEHIRNVERLETZUNGEN[2016/08]
English:COMPOSITIONS AND METHODS FOR THE TREATMENT OF BRAIN INJURY[2016/08]
French:COMPOSITIONS ET MÉTHODES POUR LE TRAITEMENT DES LÉSIONS CÉRÉBRALES[2016/08]
Entry into regional phase16.11.2015National basic fee paid 
16.11.2015Search fee paid 
16.11.2015Designation fee(s) paid 
16.11.2015Examination fee paid 
Examination procedure16.11.2015Examination requested  [2016/08]
13.07.2017Amendment by applicant (claims and/or description)
14.01.2019Despatch of a communication from the examining division (Time limit: M06)
11.07.2019Reply to a communication from the examining division
18.03.2020Communication of intention to grant the patent
17.07.2020Fee for grant paid
17.07.2020Fee for publishing/printing paid
17.07.2020Receipt of the translation of the claim(s)
Opposition(s)27.05.2021No opposition filed within time limit [2021/31]
Fees paidRenewal fee
25.04.2016Renewal fee patent year 03
10.04.2017Renewal fee patent year 04
11.06.2018Renewal fee patent year 05
15.04.2019Renewal fee patent year 06
31.03.2020Renewal fee patent year 07
Penalty fee
Additional fee for renewal fee
30.04.201805   M06   Fee paid on   11.06.2018
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU15.04.2014
AL26.08.2020
AT26.08.2020
CY26.08.2020
CZ26.08.2020
DK26.08.2020
EE26.08.2020
FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
MC26.08.2020
MK26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
SI26.08.2020
SK26.08.2020
SM26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
IE15.04.2021
LU15.04.2021
BE30.04.2021
CH30.04.2021
LI30.04.2021
[2024/22]
Former [2023/30]HU15.04.2014
AL26.08.2020
AT26.08.2020
CY26.08.2020
CZ26.08.2020
DK26.08.2020
EE26.08.2020
FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
MC26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
SI26.08.2020
SK26.08.2020
SM26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
IE15.04.2021
LU15.04.2021
BE30.04.2021
CH30.04.2021
LI30.04.2021
Former [2023/29]HU15.04.2014
AL26.08.2020
AT26.08.2020
CZ26.08.2020
DK26.08.2020
EE26.08.2020
FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
MC26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
SI26.08.2020
SK26.08.2020
SM26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
IE15.04.2021
LU15.04.2021
BE30.04.2021
CH30.04.2021
LI30.04.2021
Former [2022/34]AL26.08.2020
AT26.08.2020
CZ26.08.2020
DK26.08.2020
EE26.08.2020
FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
MC26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
SI26.08.2020
SK26.08.2020
SM26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
IE15.04.2021
LU15.04.2021
BE30.04.2021
CH30.04.2021
LI30.04.2021
Former [2022/23]AL26.08.2020
AT26.08.2020
CZ26.08.2020
DK26.08.2020
EE26.08.2020
FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
MC26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
SI26.08.2020
SK26.08.2020
SM26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
IE15.04.2021
LU15.04.2021
CH30.04.2021
LI30.04.2021
Former [2022/21]AL26.08.2020
AT26.08.2020
CZ26.08.2020
DK26.08.2020
EE26.08.2020
FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
MC26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
SI26.08.2020
SK26.08.2020
SM26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
PT28.12.2020
IE15.04.2021
LU15.04.2021
CH30.04.2021
LI30.04.2021
Former [2022/10]AL26.08.2020
AT26.08.2020
CZ26.08.2020
DK26.08.2020
EE26.08.2020
FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
MC26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
SI26.08.2020
SK26.08.2020
SM26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
PT28.12.2020
LU15.04.2021
CH30.04.2021
LI30.04.2021
Former [2022/04]AL26.08.2020
AT26.08.2020
CZ26.08.2020
DK26.08.2020
EE26.08.2020
FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
MC26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
SI26.08.2020
SK26.08.2020
SM26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
LU15.04.2021
Former [2021/50]AL26.08.2020
AT26.08.2020
CZ26.08.2020
DK26.08.2020
EE26.08.2020
FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
MC26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
SI26.08.2020
SK26.08.2020
SM26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
Former [2021/36]AL26.08.2020
AT26.08.2020
CZ26.08.2020
DK26.08.2020
EE26.08.2020
FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
SI26.08.2020
SK26.08.2020
SM26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
Former [2021/28]AL26.08.2020
AT26.08.2020
CZ26.08.2020
DK26.08.2020
EE26.08.2020
FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
SK26.08.2020
SM26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
Former [2021/25]AL26.08.2020
AT26.08.2020
CZ26.08.2020
DK26.08.2020
EE26.08.2020
FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
SM26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
Former [2021/24]AT26.08.2020
CZ26.08.2020
DK26.08.2020
EE26.08.2020
FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
SM26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
Former [2021/23]CZ26.08.2020
DK26.08.2020
EE26.08.2020
FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
SM26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
Former [2021/22]CZ26.08.2020
DK26.08.2020
EE26.08.2020
FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
NL26.08.2020
PL26.08.2020
RO26.08.2020
RS26.08.2020
SE26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
Former [2021/21]DK26.08.2020
FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
NL26.08.2020
PL26.08.2020
RS26.08.2020
SE26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
Former [2021/12]FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
NL26.08.2020
PL26.08.2020
RS26.08.2020
SE26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
Former [2021/10]FI26.08.2020
HR26.08.2020
LT26.08.2020
LV26.08.2020
PL26.08.2020
RS26.08.2020
SE26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
IS26.12.2020
PT28.12.2020
Former [2021/09]FI26.08.2020
LT26.08.2020
SE26.08.2020
BG26.11.2020
NO26.11.2020
GR27.11.2020
PT28.12.2020
Former [2021/08]FI26.08.2020
LT26.08.2020
SE26.08.2020
BG26.11.2020
NO26.11.2020
PT28.12.2020
Former [2021/07]FI26.08.2020
LT26.08.2020
NO26.11.2020
Documents cited:Search[I]WO2007064618  (NOVARTIS AG [CH], et al) [I] 1-8 * page 17, paragraph 3 *;
 [I]US2009170786  (GREENBERG NORMAN ALAN [US]) [I] 1-8 * column 2, lines 16-29 *;
 [X]  - HARAGUCHI TAMAMI ET AL, "Evaluation of the odour of Aminoleban EN, taste-masked with flavoured powders, by human and electronic noses", JOURNAL OF PHARMACY AND PHARMACO, JOHN WILEY & SONS LTD, GB, (20130401), vol. 65, no. 4, ISSN 2042-7158, pages 503 - 511, XP009192718 [X] 1-8 * page 503 - page 504 *
 [A]  - Junji Mukai ET AL, "The effect of taste-odour interactions on the palatability of nutritional products for liver failure", Asian Journal of Pharmaceutical Sciences, (20090101), pages 46 - 55, URL: http://www.asianjps.com:8080/Jweb_ajps/CN/article/downloadArticleFile.do?attachType=PDF&id=162, XP055326699 [A] 1-8 * abstract *
International search[A]US5028622  (PLAITAKIS ANDREAS [US]);
 [X]US2004087490  (TROUP JOHN P [CH], et al);
 [A]US2011065715  (STRITTMATTER STEPHEN M [US], et al);
 [Y]  - AQUILANI ET AL., "Branched-chain amino acids enhance the cognitive recovery of patients with severe traumatic brain injury.", ARCH PHYS MED REHABIL., (2005), vol. 86, no. 9, page 1732, XP005110287

DOI:   http://dx.doi.org/10.1016/j.apmr.2005.03.022
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