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Extract from the Register of European Patents

EP About this file: EP3004134

EP3004134 - PEPTIDE LIGATION [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  03.01.2020
Database last updated on 05.10.2024
FormerThe patent has been granted
Status updated on  25.01.2019
FormerGrant of patent is intended
Status updated on  23.01.2019
FormerExamination is in progress
Status updated on  17.01.2019
FormerGrant of patent is intended
Status updated on  13.09.2018
FormerExamination is in progress
Status updated on  16.03.2018
Most recent event   Tooltip01.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 03.08.2022  [2022/31]
Applicant(s)For all designated states
The University of Sydney
Parramatta Road
Sydney
New South Wales 2006 / AU
[2019/08]
Former [2016/15]For all designated states
The University Of Sydney
Parramatta Road The University of Sydney
New South Wales 2006 / AU
Inventor(s)01 / PAYNE, Richard, J.
Unit 11
1 Gibson Street
Camperdown NSW 2050 / AU
02 / THOMPSON, Robert, E.
25/471 South Dowling Street
Surry Hills NSW 2026 / AU
 [2016/15]
Representative(s)V.O.
P.O. Box 87930
2508 DH Den Haag / NL
[2016/15]
Application number, filing date14806955.204.06.2014
[2016/15]
WO2014AU00583
Priority number, dateAU2013090200604.06.2013         Original published format: AU 2013902006
[2016/15]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2014194361
Date:11.12.2014
Language:EN
[2014/50]
Type: A1 Application with search report 
No.:EP3004134
Date:13.04.2016
Language:EN
The application published by WIPO in one of the EPO official languages on 11.12.2014 takes the place of the publication of the European patent application.
[2016/15]
Type: B1 Patent specification 
No.:EP3004134
Date:27.02.2019
Language:EN
[2019/09]
Search report(s)International search report - published on:AU11.12.2014
(Supplementary) European search report - dispatched on:EP16.03.2017
ClassificationIPC:C07K1/107, C07C319/02, C07C321/04, C07K7/06, C07K7/08, C07C319/14, C07C323/59
[2017/02]
CPC:
C07C319/02 (EP,US); C07K1/062 (US); C07C319/14 (EP,US);
C07K1/026 (EP,US); C07K1/1072 (EP,US); C07K7/08 (US);
Y02P20/55 (EP,US) (-)
C-Set:
C07C319/02, C07C323/58 (US,EP);
C07C319/02, C07C323/59 (US,EP);
C07C319/14, C07C323/59 (EP,US)
Former IPC [2016/15]C07K1/107, C07C319/02, C07C321/04, C07K7/06, C07K7/08
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/15]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:PEPTIDLIGATION[2016/15]
English:PEPTIDE LIGATION[2016/15]
French:LIGATURE PEPTIDIQUE[2016/15]
Entry into regional phase17.11.2015National basic fee paid 
17.11.2015Search fee paid 
17.11.2015Designation fee(s) paid 
17.11.2015Examination fee paid 
Examination procedure17.11.2015Examination requested  [2016/15]
28.09.2017Amendment by applicant (claims and/or description)
20.03.2018Despatch of a communication from the examining division (Time limit: M04)
04.05.2018Reply to a communication from the examining division
14.09.2018Communication of intention to grant the patent
15.01.2019Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
15.01.2019Fee for grant paid
15.01.2019Fee for publishing/printing paid
23.01.2019Information about intention to grant a patent
23.01.2019Receipt of the translation of the claim(s)
Opposition(s)28.11.2019No opposition filed within time limit [2020/06]
Fees paidRenewal fee
27.06.2016Renewal fee patent year 03
27.06.2017Renewal fee patent year 04
27.06.2018Renewal fee patent year 05
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU04.06.2014
AL27.02.2019
AT27.02.2019
CY27.02.2019
CZ27.02.2019
EE27.02.2019
ES27.02.2019
FI27.02.2019
HR27.02.2019
IT27.02.2019
LT27.02.2019
LV27.02.2019
MK27.02.2019
MT27.02.2019
NL27.02.2019
PL27.02.2019
RO27.02.2019
RS27.02.2019
SE27.02.2019
SI27.02.2019
SK27.02.2019
SM27.02.2019
TR27.02.2019
BG27.05.2019
NO27.05.2019
GR28.05.2019
IS27.06.2019
PT27.06.2019
[2022/31]
Former [2021/34]HU04.06.2014
AL27.02.2019
AT27.02.2019
CY27.02.2019
CZ27.02.2019
EE27.02.2019
ES27.02.2019
FI27.02.2019
HR27.02.2019
IT27.02.2019
LT27.02.2019
LV27.02.2019
MT27.02.2019
NL27.02.2019
PL27.02.2019
RO27.02.2019
RS27.02.2019
SE27.02.2019
SI27.02.2019
SK27.02.2019
SM27.02.2019
TR27.02.2019
BG27.05.2019
NO27.05.2019
GR28.05.2019
IS27.06.2019
PT27.06.2019
Former [2021/33]HU04.06.2014
AL27.02.2019
AT27.02.2019
CY27.02.2019
CZ27.02.2019
EE27.02.2019
ES27.02.2019
FI27.02.2019
HR27.02.2019
IT27.02.2019
LT27.02.2019
LV27.02.2019
NL27.02.2019
PL27.02.2019
RO27.02.2019
RS27.02.2019
SE27.02.2019
SI27.02.2019
SK27.02.2019
SM27.02.2019
TR27.02.2019
BG27.05.2019
NO27.05.2019
GR28.05.2019
IS27.06.2019
PT27.06.2019
Former [2021/26]AL27.02.2019
AT27.02.2019
CY27.02.2019
CZ27.02.2019
EE27.02.2019
ES27.02.2019
FI27.02.2019
HR27.02.2019
IT27.02.2019
LT27.02.2019
LV27.02.2019
NL27.02.2019
PL27.02.2019
RO27.02.2019
RS27.02.2019
SE27.02.2019
SI27.02.2019
SK27.02.2019
SM27.02.2019
TR27.02.2019
BG27.05.2019
NO27.05.2019
GR28.05.2019
IS27.06.2019
PT27.06.2019
Former [2020/17]AL27.02.2019
AT27.02.2019
CZ27.02.2019
EE27.02.2019
ES27.02.2019
FI27.02.2019
HR27.02.2019
IT27.02.2019
LT27.02.2019
LV27.02.2019
NL27.02.2019
PL27.02.2019
RO27.02.2019
RS27.02.2019
SE27.02.2019
SI27.02.2019
SK27.02.2019
SM27.02.2019
TR27.02.2019
BG27.05.2019
NO27.05.2019
GR28.05.2019
IS27.06.2019
PT27.06.2019
Former [2020/13]AL27.02.2019
AT27.02.2019
CZ27.02.2019
EE27.02.2019
ES27.02.2019
FI27.02.2019
HR27.02.2019
IT27.02.2019
LT27.02.2019
LV27.02.2019
NL27.02.2019
PL27.02.2019
RO27.02.2019
RS27.02.2019
SE27.02.2019
SI27.02.2019
SK27.02.2019
SM27.02.2019
BG27.05.2019
NO27.05.2019
GR28.05.2019
IS27.06.2019
PT27.06.2019
Former [2020/03]AL27.02.2019
AT27.02.2019
CZ27.02.2019
EE27.02.2019
ES27.02.2019
FI27.02.2019
HR27.02.2019
IT27.02.2019
LT27.02.2019
LV27.02.2019
NL27.02.2019
PL27.02.2019
RO27.02.2019
RS27.02.2019
SE27.02.2019
SK27.02.2019
SM27.02.2019
BG27.05.2019
NO27.05.2019
GR28.05.2019
IS27.06.2019
PT27.06.2019
Former [2019/52]AL27.02.2019
CZ27.02.2019
EE27.02.2019
ES27.02.2019
FI27.02.2019
HR27.02.2019
IT27.02.2019
LT27.02.2019
LV27.02.2019
NL27.02.2019
PL27.02.2019
RO27.02.2019
RS27.02.2019
SE27.02.2019
SK27.02.2019
SM27.02.2019
BG27.05.2019
NO27.05.2019
GR28.05.2019
IS27.06.2019
PT27.06.2019
Former [2019/51]AL27.02.2019
CZ27.02.2019
EE27.02.2019
ES27.02.2019
FI27.02.2019
HR27.02.2019
IT27.02.2019
LT27.02.2019
LV27.02.2019
NL27.02.2019
RO27.02.2019
RS27.02.2019
SE27.02.2019
SK27.02.2019
SM27.02.2019
BG27.05.2019
NO27.05.2019
GR28.05.2019
IS27.06.2019
PT27.06.2019
Former [2019/49]AL27.02.2019
CZ27.02.2019
EE27.02.2019
ES27.02.2019
FI27.02.2019
HR27.02.2019
IT27.02.2019
LT27.02.2019
LV27.02.2019
NL27.02.2019
RO27.02.2019
RS27.02.2019
SE27.02.2019
SK27.02.2019
BG27.05.2019
NO27.05.2019
GR28.05.2019
IS27.06.2019
PT27.06.2019
Former [2019/47]ES27.02.2019
FI27.02.2019
HR27.02.2019
IT27.02.2019
LT27.02.2019
LV27.02.2019
NL27.02.2019
RS27.02.2019
SE27.02.2019
BG27.05.2019
NO27.05.2019
GR28.05.2019
IS27.06.2019
PT27.06.2019
Former [2019/46]FI27.02.2019
HR27.02.2019
IT27.02.2019
LT27.02.2019
LV27.02.2019
NL27.02.2019
RS27.02.2019
SE27.02.2019
BG27.05.2019
NO27.05.2019
GR28.05.2019
IS27.06.2019
PT27.06.2019
Former [2019/39]FI27.02.2019
HR27.02.2019
LT27.02.2019
LV27.02.2019
NL27.02.2019
RS27.02.2019
SE27.02.2019
BG27.05.2019
NO27.05.2019
GR28.05.2019
IS27.06.2019
PT27.06.2019
Former [2019/38]FI27.02.2019
LT27.02.2019
NL27.02.2019
SE27.02.2019
BG27.05.2019
NO27.05.2019
GR28.05.2019
PT27.06.2019
Former [2019/37]FI27.02.2019
LT27.02.2019
NL27.02.2019
SE27.02.2019
NO27.05.2019
GR28.05.2019
PT27.06.2019
Former [2019/34]FI27.02.2019
LT27.02.2019
NL27.02.2019
SE27.02.2019
NO27.05.2019
PT27.06.2019
Former [2019/33]FI27.02.2019
LT27.02.2019
NO27.05.2019
PT27.06.2019
Documents cited:Search   [ ] - No further relevant documents disclosed
International search[X]  - CAS, (20041116), Database accession no. 781601-14-7, URL: STN, XP055297229 [X] 40-43 * 4-mercapto-glutamic acid *
 [X]  - CAS, (20030305), Database accession no. 496919-12-1, URL: STN, XP055297234 [X] 40-43 * 3-mercapto-L-aspartic acid *
 [X]  - KRASNOV V. P. et al., "Synthesis of 4-mercaptoglytamic acid derivatives", Russian Journal of Organic Chemistry ''., (19990000), vol. 35, no. 4, pages 572 - 577, XP 008181363 [X] 40-43 * Scheme 2 and compound VIII page 573 *
 [XY]  - SHIBATA N. et al., "Electrophilic sulfenylation in a stereocontrolled synthesis of protected (2R,3R)-3-mercaptoaspartic acid from L-aspartic acid", Tetrahedron, (19960000), vol. 52, no. 39, pages 12839 - 12852, XP 055297177 [X] 1-16 * Scheme 1 and compound 8 page 12840, compound 13 page 12841, Scheme 4 page 12842, compound 18 Scheme 5, compound 22 Scheme 7 page 12843 and compound 24 and 25 Scheme 9 page 12844 Whole document * [Y] 17-18, 20, 22-26, 28, 30-35 and 37
 [XY]  - SHIBATA N . et al., "A stereocontrolled synthesis of protected (2R,3R)-3- mercaptoaspartic acid via a beta-aspartyl enolate sulfenylation", Synlett., (19960000), vol. 6, doi:doi:10.1055/s-1996-5490, pages 519 - 520, XP 001182595 [X] 1-16 * Scheme 1 page 519, compound 7 page 519, compound 12 Scheme 2 and Scheme 3 page 519 and compounds 18 19, 20 and 21 Scheme 4 page 520 Whole document * [Y] 17-18, 20, 22-26, 28, 30-35 and 37
 [Y]  - HASSE C. et al., "Native Chemical Ligation at Valine", Angew. Chem. Int. Ed., (20080000), vol. 47, pages 6807 - 6810, XP 008146650 [Y] 17-18, 20, 22-26, 28, 31-35 and 37 * see Fig. 1 page 6808 and Fig. 2 page 6809 *
 [Y]  - SIMAN P. et al., "Chemical Synthesis and Expression of the HIV-1 Rev Protein", ChemBioChem., (20110000), vol. 12, pages 1097 - 1104, XP 000051763 [Y] 17-18, 20, 22-26, 28, 30-35 and 37 * "One-pot synthesis of Rev protein" page 1102 *
 [Y]  - CHEN J . et al., "A program tor ligation at threonine sites: application to the controlled total synthesis of glycopeptides", Tetrahedron ., (20100000), vol. 66, doi:doi:10.1016/j.tet.2010.01.067, pages 2277 - 2283, XP 026932573 [Y] 17-18, 20, 22-26, 28, 31-35 and 37 * Table 1 page 2279 *
 [Y]  - TAN Z. et al., "Insights into the Finer Issues of Native Chemical Ligation: An Approach to Cascade Ligations", Angew. Chem. Int. Ed., (20100000), vol. 49, pages 9500 - 9503, XP 055297182 [Y] 17-18, 20, 22-26, 28, 31-35 and 37 * Table 1 page 9501 *
 [A]  - SIMAN P. et al., "Native chemical ligation at glutamine", Organic Letters., (20120000), vol. 14, no. 6, pages 1520 - 1523, XP 055297183 [A] 1-43 * see whole document especially Scheme 2 page 1521 and the last paragraph column 1 page 1523 *
 [PX]  - THOMPSON, R. E. et al., "Chemoselective Peptide Ligation-Desulfurization at Aspaitate", Angew. Chem. Int. Ed., (20130000), vol. 52, no. 37, pages 9723 - 9727, XP 055297184 [PX] 1-18 and 20-43 * see whole document *
 [PX]  - THOMPSON, R. E. et al., "Trifluoroethanethiol: An Additive for Efficient One-Pot Peptide Ligation -Desulfurization Chemistry", J. Am. Chem. Soc., (20140000), vol. 136, pages 8161 - 8164, XP 055297185 [PX] 1-43 * see whole document *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.