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Extract from the Register of European Patents

EP About this file: EP3046586

EP3046586 - METHODS OF TREATMENT USING BIS-POLYMER LIPID-PEPTIDE CONJUGATES AND NANOPARTICLES THEREOF [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  13.05.2022
Database last updated on 20.07.2024
FormerThe patent has been granted
Status updated on  12.06.2021
FormerGrant of patent is intended
Status updated on  04.10.2020
FormerExamination is in progress
Status updated on  06.04.2018
Most recent event   Tooltip27.04.2024Lapse of the patent in a contracting state
New state(s): MK		published on 29.05.2024  [2024/22]
Applicant(s)For all designated states
The Regents of the University of California
1111 Franklin Street, 12th Floor
Oakland, CA 94607 / US
[2016/30]
Inventor(s)01 / XU, Ting
2122 Jefferson Avenue
Berkeley, California 94703 / US
02 / DUBE, Nikhil
1977 Garden Avenue (207)
Burlingame, California 94704 / US
 [2017/01]
Former [2016/30]01 / XU, Ting
2122 Jefferson Avenue
Berkeley, California 94703 / US
02 / DUBE, Nikhil
2533 Hillegass Avenue 206
Berkeley, California 94704 / US
Representative(s)J A Kemp LLP
80 Turnmill Street
London EC1M 5QU / GB
[N/P]
Former [2021/27]J A Kemp LLP
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Former [2016/30]Campbell, Patrick John Henry
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Application number, filing date14845308.718.09.2014
[2016/30]
WO2014US56287
Priority number, dateUS201361880068P19.09.2013         Original published format: US 201361880068 P
US201361889324P10.10.2013         Original published format: US 201361889324 P
[2016/30]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2015042252
Date:26.03.2015
Language:EN
[2015/12]
Type: A1 Application with search report 
No.:EP3046586
Date:27.07.2016
Language:EN
The application published by WIPO in one of the EPO official languages on 26.03.2015 takes the place of the publication of the European patent application.
[2016/30]
Type: B1 Patent specification 
No.:EP3046586
Date:07.07.2021
Language:EN
[2021/27]
Search report(s)International search report - published on:US26.03.2015
(Supplementary) European search report - dispatched on:EP20.04.2017
ClassificationIPC:A61K9/00, A61K31/704, A61K31/337, A61K9/16, A61K9/127, A61K49/00, A61K31/436, A61K51/12, A61K9/107, A61K47/42, A61K47/60, A61K47/54
[2020/37]
CPC:
A61K47/42 (EP); A61K31/337 (EP); A61K31/436 (EP);
A61K31/704 (EP); A61K47/543 (EP); A61K47/60 (EP);
A61K49/0082 (EP); A61K51/1227 (EP); A61K9/0019 (EP);
A61K9/107 (EP); A61K9/1271 (EP); A61K9/1658 (EP) (-)
Former IPC [2017/20]A61K9/00, A61K47/42, A61K9/107, A61K51/12, A61K31/436, A61K49/00, A61K9/127, A61K9/16, A61K31/337, A61K31/704
Former IPC [2016/30]A61K47/42
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/30]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:BEHANDLUNGSVERFAHREN MIT BIS-POLYMER-LIPIDPEPTID-KONJUGATEN UND NANOPARTIKELN DARAUS[2016/30]
English:METHODS OF TREATMENT USING BIS-POLYMER LIPID-PEPTIDE CONJUGATES AND NANOPARTICLES THEREOF[2016/30]
French:PROCÉDÉS DE TRAITEMENT AU MOYEN DE CONJUGUÉS BIS-POLYMÈRES PEPTIDE-LIPIDE ET DE LEURS NANOPARTICULES[2016/30]
Entry into regional phase12.04.2016National basic fee paid 
12.04.2016Search fee paid 
12.04.2016Designation fee(s) paid 
12.04.2016Examination fee paid 
Examination procedure12.04.2016Examination requested  [2016/30]
17.11.2017Amendment by applicant (claims and/or description)
10.04.2018Despatch of a communication from the examining division (Time limit: M06)
05.10.2018Reply to a communication from the examining division
14.01.2020Despatch of a communication from the examining division (Time limit: M06)
08.07.2020Reply to a communication from the examining division
05.10.2020Communication of intention to grant the patent
12.03.2021Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time
25.05.2021Fee for grant paid
25.05.2021Fee for publishing/printing paid
25.05.2021Receipt of the translation of the claim(s)
Opposition(s)08.04.2022No opposition filed within time limit [2022/24]
Request for further processing for:The application is deemed to be withdrawn due to failure to fulfill actions required for granting the patent
25.05.2021Request for further processing filed
25.05.2021Full payment received (date of receipt of payment)
Request granted
03.06.2021Decision despatched
Fees paidRenewal fee
27.09.2016Renewal fee patent year 03
27.09.2017Renewal fee patent year 04
27.09.2018Renewal fee patent year 05
27.09.2019Renewal fee patent year 06
29.03.2021Renewal fee patent year 07
Penalty fee
Additional fee for renewal fee
30.09.202007   M06   Fee paid on   29.03.2021
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU18.09.2014
AL07.07.2021
AT07.07.2021
CY07.07.2021
CZ07.07.2021
DK07.07.2021
EE07.07.2021
ES07.07.2021
FI07.07.2021
HR07.07.2021
IT07.07.2021
LT07.07.2021
LV07.07.2021
MC07.07.2021
MK07.07.2021
NL07.07.2021
PL07.07.2021
RO07.07.2021
RS07.07.2021
SE07.07.2021
SI07.07.2021
SK07.07.2021
SM07.07.2021
IE18.09.2021
LU18.09.2021
BE30.09.2021
CH30.09.2021
FR30.09.2021
LI30.09.2021
BG07.10.2021
GB07.10.2021
NO07.10.2021
GR08.10.2021
IS07.11.2021
PT08.11.2021
DE01.04.2022
[2024/22]
Former [2023/30]HU18.09.2014
AL07.07.2021
AT07.07.2021
CY07.07.2021
CZ07.07.2021
DK07.07.2021
EE07.07.2021
ES07.07.2021
FI07.07.2021
HR07.07.2021
IT07.07.2021
LT07.07.2021
LV07.07.2021
MC07.07.2021
NL07.07.2021
PL07.07.2021
RO07.07.2021
RS07.07.2021
SE07.07.2021
SI07.07.2021
SK07.07.2021
SM07.07.2021
IE18.09.2021
LU18.09.2021
BE30.09.2021
CH30.09.2021
FR30.09.2021
LI30.09.2021
BG07.10.2021
GB07.10.2021
NO07.10.2021
GR08.10.2021
IS07.11.2021
PT08.11.2021
DE01.04.2022
Former [2023/27]HU18.09.2014
AL07.07.2021
AT07.07.2021
CZ07.07.2021
DK07.07.2021
EE07.07.2021
ES07.07.2021
FI07.07.2021
HR07.07.2021
IT07.07.2021
LT07.07.2021
LV07.07.2021
MC07.07.2021
NL07.07.2021
PL07.07.2021
RO07.07.2021
RS07.07.2021
SE07.07.2021
SI07.07.2021
SK07.07.2021
SM07.07.2021
IE18.09.2021
LU18.09.2021
BE30.09.2021
CH30.09.2021
FR30.09.2021
LI30.09.2021
BG07.10.2021
GB07.10.2021
NO07.10.2021
GR08.10.2021
IS07.11.2021
PT08.11.2021
DE01.04.2022
Former [2022/37]AL07.07.2021
AT07.07.2021
CZ07.07.2021
DK07.07.2021
EE07.07.2021
ES07.07.2021
FI07.07.2021
HR07.07.2021
IT07.07.2021
LT07.07.2021
LV07.07.2021
MC07.07.2021
NL07.07.2021
PL07.07.2021
RO07.07.2021
RS07.07.2021
SE07.07.2021
SI07.07.2021
SK07.07.2021
SM07.07.2021
IE18.09.2021
LU18.09.2021
BE30.09.2021
CH30.09.2021
FR30.09.2021
LI30.09.2021
BG07.10.2021
GB07.10.2021
NO07.10.2021
GR08.10.2021
IS07.11.2021
PT08.11.2021
DE01.04.2022
Former [2022/36]AL07.07.2021
AT07.07.2021
CZ07.07.2021
DK07.07.2021
EE07.07.2021
ES07.07.2021
FI07.07.2021
HR07.07.2021
IT07.07.2021
LT07.07.2021
LV07.07.2021
MC07.07.2021
NL07.07.2021
PL07.07.2021
RO07.07.2021
RS07.07.2021
SE07.07.2021
SI07.07.2021
SK07.07.2021
SM07.07.2021
IE18.09.2021
LU18.09.2021
BE30.09.2021
FR30.09.2021
BG07.10.2021
GB07.10.2021
NO07.10.2021
GR08.10.2021
IS07.11.2021
PT08.11.2021
DE01.04.2022
Former [2022/35]AL07.07.2021
AT07.07.2021
CZ07.07.2021
DK07.07.2021
EE07.07.2021
ES07.07.2021
FI07.07.2021
HR07.07.2021
LT07.07.2021
LV07.07.2021
MC07.07.2021
NL07.07.2021
PL07.07.2021
RO07.07.2021
RS07.07.2021
SE07.07.2021
SI07.07.2021
SK07.07.2021
SM07.07.2021
IE18.09.2021
LU18.09.2021
BE30.09.2021
FR30.09.2021
BG07.10.2021
GB07.10.2021
NO07.10.2021
GR08.10.2021
IS07.11.2021
PT08.11.2021
DE01.04.2022
Former [2022/34]AL07.07.2021
AT07.07.2021
CZ07.07.2021
DK07.07.2021
EE07.07.2021
ES07.07.2021
FI07.07.2021
HR07.07.2021
LT07.07.2021
LV07.07.2021
MC07.07.2021
NL07.07.2021
PL07.07.2021
RO07.07.2021
RS07.07.2021
SE07.07.2021
SI07.07.2021
SK07.07.2021
SM07.07.2021
LU18.09.2021
BE30.09.2021
FR30.09.2021
BG07.10.2021
NO07.10.2021
GR08.10.2021
IS07.11.2021
PT08.11.2021
DE01.04.2022
Former [2022/33]AL07.07.2021
AT07.07.2021
CZ07.07.2021
DK07.07.2021
EE07.07.2021
ES07.07.2021
FI07.07.2021
HR07.07.2021
LT07.07.2021
LV07.07.2021
MC07.07.2021
NL07.07.2021
PL07.07.2021
RO07.07.2021
RS07.07.2021
SE07.07.2021
SI07.07.2021
SK07.07.2021
SM07.07.2021
BE30.09.2021
BG07.10.2021
NO07.10.2021
GR08.10.2021
IS07.11.2021
PT08.11.2021
DE01.04.2022
Former [2022/29]AL07.07.2021
AT07.07.2021
CZ07.07.2021
DK07.07.2021
EE07.07.2021
ES07.07.2021
FI07.07.2021
HR07.07.2021
LT07.07.2021
LV07.07.2021
MC07.07.2021
NL07.07.2021
PL07.07.2021
RO07.07.2021
RS07.07.2021
SE07.07.2021
SI07.07.2021
SK07.07.2021
SM07.07.2021
BG07.10.2021
NO07.10.2021
GR08.10.2021
IS07.11.2021
PT08.11.2021
Former [2022/25]AT07.07.2021
CZ07.07.2021
DK07.07.2021
EE07.07.2021
ES07.07.2021
FI07.07.2021
HR07.07.2021
LT07.07.2021
LV07.07.2021
MC07.07.2021
NL07.07.2021
PL07.07.2021
RO07.07.2021
RS07.07.2021
SE07.07.2021
SK07.07.2021
SM07.07.2021
BG07.10.2021
NO07.10.2021
GR08.10.2021
IS07.11.2021
PT08.11.2021
Former [2022/24]AT07.07.2021
CZ07.07.2021
DK07.07.2021
EE07.07.2021
ES07.07.2021
FI07.07.2021
HR07.07.2021
LT07.07.2021
LV07.07.2021
MC07.07.2021
NL07.07.2021
PL07.07.2021
RO07.07.2021
RS07.07.2021
SE07.07.2021
SK07.07.2021
BG07.10.2021
NO07.10.2021
GR08.10.2021
IS07.11.2021
PT08.11.2021
Former [2022/21]AT07.07.2021
DK07.07.2021
ES07.07.2021
FI07.07.2021
HR07.07.2021
LT07.07.2021
LV07.07.2021
NL07.07.2021
PL07.07.2021
RS07.07.2021
SE07.07.2021
BG07.10.2021
NO07.10.2021
GR08.10.2021
IS07.11.2021
PT08.11.2021
Former [2022/11]AT07.07.2021
ES07.07.2021
FI07.07.2021
HR07.07.2021
LT07.07.2021
LV07.07.2021
NL07.07.2021
PL07.07.2021
RS07.07.2021
SE07.07.2021
BG07.10.2021
NO07.10.2021
GR08.10.2021
IS07.11.2021
PT08.11.2021
Former [2022/09]AT07.07.2021
ES07.07.2021
FI07.07.2021
LT07.07.2021
NL07.07.2021
RS07.07.2021
SE07.07.2021
BG07.10.2021
NO07.10.2021
PT08.11.2021
Former [2022/08]AT07.07.2021
ES07.07.2021
FI07.07.2021
LT07.07.2021
NL07.07.2021
SE07.07.2021
BG07.10.2021
NO07.10.2021
Former [2022/07]AT07.07.2021
LT07.07.2021
NL07.07.2021
NO07.10.2021
Documents cited:Search[X]  - HE DONG ET AL, "Long-Circulating 15 nm Micelles Based on Amphiphilic 3-Helix Peptide-PEG Conjugates", ACS NANO, (20120626), vol. 6, no. 6, doi:10.1021/nn301142r, ISSN 1936-0851, pages 5320 - 5329, XP055046013 [X] 1-6 * Scheme 1; Materials and methods; Second paragraph on page 5322;; figures 1, 3, 5-6 *

DOI:   http://dx.doi.org/10.1021/nn301142r
International search[A]US2013101628  (WEBBER MATTHEW J [US], et al);
 [Y]US2013121917  (XU TING [US], et al);
 [Y]WO2013100704  (HANMI SCIENCE CO LTD [KR])
by applicantUS6953575
 US7534613
 US8309355
    - DONG et al., ACS NANO, (20120000), vol. 6, no. 6, pages 5320 - 5329
    - SACHSE, A. et al., Investigative Radiology, (19970000), vol. 32, no. 1, pages 44 - 50
    - LIEBERMAN, Pharmaceutical Dosage Forms, (19920000), vol. 1-3
    - NISSENBAUM, E.T., Trends in Biotech., (20080000), vol. 26, no. 8, pages 442 - 449
    - ELBAYOUMI, T.A.TORCHILIN, V.P., Eur. J. Nucl. Med. Mol. Imaging, (20060000), vol. 33, pages 1196 - 1205
    - Nanomedicine and Nanobiotechnology, (20080000), vol. 1, no. 1, pages 69 - 83
    - MOUGIN-DEGRAEF, M. et al., Int 7 J. Pharmaceutics, (20070000), vol. 344, pages 110 - 117
    - BOGDANOV, A.A. et al., Adv. Drug Del. Rev., (19990000), vol. 37, pages 279 - 293
    - TORCHILIN, V.P., Curr. Pharm. Biotech., (20000000), vol. 1, pages 183 - 215
    - GOLDSPIEL et al., Clinical Pharmacy, (19930000), vol. 12, pages 488 - 505
    - WUWU, Biotherapy, (19910000), vol. 3, pages 87 - 95
    - TOLSTOSHEV, Ann. Rev. Pharmacol. Toxicol., (19930000), vol. 32, pages 573 - 596
    - MULLIGAN, Science, (19930000), vol. 260, pages 926 - 932
    - MORGANANDERSON, Ann. Rev. Biochem., (19930000), vol. 62, pages 191 - 217
    - TIBTECH, (19930500), vol. 11, no. 5, pages 155 - 215
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.