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Extract from the Register of European Patents

EP About this file: EP3054969

EP3054969 - AGONISTS OF GUANYLATE CYCLASE USEFUL FOR THE TREATMENT OF OPIOID INDUCED DYSFUNCTIONS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  14.01.2022
Database last updated on 05.10.2024
FormerThe patent has been granted
Status updated on  05.02.2021
FormerGrant of patent is intended
Status updated on  17.09.2020
FormerExamination is in progress
Status updated on  27.07.2020
FormerGrant of patent is intended
Status updated on  23.04.2020
FormerExamination is in progress
Status updated on  19.01.2018
Most recent event   Tooltip06.09.2024Lapse of the patent in a contracting state
New state(s): MT		published on 09.10.2024 [2024/41]
Applicant(s)For all designated states
Bausch Health Ireland Limited
3013 Lake Drive
Citywest Business Campus
Dublin 24 / IE
[2019/42]
Former [2017/15]For all designated states
Synergy Pharmaceuticals Inc.
420 Lexington Avenue
Suite 2012
New York, NY 10170 / US
Former [2016/33]For all designated states
Synergy Pharmaceuticals Inc.
420 Lexington Avenue
New York, NY 10170 / US
Inventor(s)01 / SHAILUBHAI, Kunwar
2707 Baldeagle Circle
Audubon, Pennsylvania 19403 / US
02 / PALEJWALA, Vaseem
2029 Church Avenue
Scotch Plains, New Jersey 07076 / US
 [2016/33]
Representative(s)Bassil, Nicholas Charles
Kilburn & Strode LLP
Lacon London
84 Theobalds Road
London WC1X 8NL / GB
[2021/10]
Former [2016/33]Cooley (UK) LLP
Dashwood
69 Old Broad Street
London EC2M 1QS / GB
Application number, filing date14851594.310.10.2014
[2016/33]
WO2014US60157
Priority number, dateUS201361889308P10.10.2013         Original published format: US 201361889308 P
[2016/33]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2015054649
Date:16.04.2015
Language:EN
[2015/15]
Type: A2 Application without search report 
No.:EP3054969
Date:17.08.2016
Language:EN
The application published by WIPO in one of the EPO official languages on 16.04.2015 takes the place of the publication of the European patent application.
[2016/33]
Type: B1 Patent specification 
No.:EP3054969
Date:10.03.2021
Language:EN
[2021/10]
Search report(s)International search report - published on:US06.08.2015
(Supplementary) European search report - dispatched on:EP15.02.2017
ClassificationIPC:A61K38/10, A61K38/00, A61K38/12, A61P1/10
[2017/11]
CPC:
A61K31/135 (EP,IL,US); A61K38/10 (IL,US); A61K31/192 (EP,IL,US);
A61K31/222 (EP,IL,US); A61K31/4468 (EP,IL,US); A61K31/451 (EP,IL,US);
A61K31/485 (EP,IL,US); A61K31/519 (EP,IL,US); A61K31/53 (EP,IL,US);
A61K38/04 (EP,IL,US); A61K38/51 (EP,IL,US); A61K45/06 (IL,US);
A61P1/04 (EP,IL); A61P1/10 (EP,IL,US); A61P11/00 (EP,IL);
A61P43/00 (EP,IL) (-)
C-Set:
A61K31/135, A61K2300/00 (EP,US);
A61K31/192, A61K2300/00 (US,EP);
A61K31/222, A61K2300/00 (EP,US);
A61K31/4468, A61K2300/00 (EP,US);
A61K31/451, A61K2300/00 (EP,US);
A61K31/485, A61K2300/00 (US,EP);
A61K31/519, A61K2300/00 (US,EP);
A61K31/53, A61K2300/00 (US,EP)
(-)
Former IPC [2016/33]A61K38/10, A61K38/00, A61K38/12
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/33]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:GUNAYLATCYCLASE-CYCLASE-AGONISTEN ZUR BEHANDLUNG VON OPIOIDINDUZIERTEN STÖRUNGEN[2016/33]
English:AGONISTS OF GUANYLATE CYCLASE USEFUL FOR THE TREATMENT OF OPIOID INDUCED DYSFUNCTIONS[2016/33]
French:AGONISTES DE GUANYLATE CYCLASE UTILES POUR LE TRAITEMENT DE TROUBLES INDUITS PAR LES OPIOÏDES[2016/33]
Entry into regional phase25.04.2016National basic fee paid 
25.04.2016Search fee paid 
25.04.2016Designation fee(s) paid 
25.04.2016Examination fee paid 
Examination procedure25.04.2016Examination requested  [2016/33]
13.09.2017Amendment by applicant (claims and/or description)
22.01.2018Despatch of a communication from the examining division (Time limit: M06)
01.08.2018Reply to a communication from the examining division
19.11.2018Despatch of a communication from the examining division (Time limit: M06)
28.06.2019Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
23.08.2019Reply to a communication from the examining division
21.10.2019Despatch of a communication from the examining division (Time limit: M04)
20.02.2020Reply to a communication from the examining division
24.04.2020Communication of intention to grant the patent
24.07.2020Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
18.09.2020Communication of intention to grant the patent
27.01.2021Fee for grant paid
27.01.2021Fee for publishing/printing paid
27.01.2021Receipt of the translation of the claim(s)
Opposition(s)13.12.2021No opposition filed within time limit [2022/07]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
23.08.2019Request for further processing filed
23.08.2019Full payment received (date of receipt of payment)
Request granted
04.09.2019Decision despatched
Fees paidRenewal fee
27.10.2016Renewal fee patent year 03
27.10.2017Renewal fee patent year 04
29.10.2018Renewal fee patent year 05
11.10.2019Renewal fee patent year 06
09.10.2020Renewal fee patent year 07
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU10.10.2014
AL10.03.2021
AT10.03.2021
CY10.03.2021
CZ10.03.2021
DK10.03.2021
EE10.03.2021
ES10.03.2021
FI10.03.2021
HR10.03.2021
IT10.03.2021
LT10.03.2021
LV10.03.2021
MC10.03.2021
MK10.03.2021
MT10.03.2021
NL10.03.2021
PL10.03.2021
RO10.03.2021
RS10.03.2021
SE10.03.2021
SI10.03.2021
SK10.03.2021
SM10.03.2021
TR10.03.2021
BG10.06.2021
NO10.06.2021
GR11.06.2021
IS10.07.2021
PT12.07.2021
IE10.10.2021
LU10.10.2021
BE31.10.2021
CH31.10.2021
LI31.10.2021
[2024/41]
Former [2024/29]HU10.10.2014
AL10.03.2021
AT10.03.2021
CY10.03.2021
CZ10.03.2021
DK10.03.2021
EE10.03.2021
ES10.03.2021
FI10.03.2021
HR10.03.2021
IT10.03.2021
LT10.03.2021
LV10.03.2021
MC10.03.2021
MK10.03.2021
NL10.03.2021
PL10.03.2021
RO10.03.2021
RS10.03.2021
SE10.03.2021
SI10.03.2021
SK10.03.2021
SM10.03.2021
TR10.03.2021
BG10.06.2021
NO10.06.2021
GR11.06.2021
IS10.07.2021
PT12.07.2021
IE10.10.2021
LU10.10.2021
BE31.10.2021
CH31.10.2021
LI31.10.2021
Former [2024/22]HU10.10.2014
AL10.03.2021
AT10.03.2021
CY10.03.2021
CZ10.03.2021
DK10.03.2021
EE10.03.2021
ES10.03.2021
FI10.03.2021
HR10.03.2021
IT10.03.2021
LT10.03.2021
LV10.03.2021
MC10.03.2021
MK10.03.2021
NL10.03.2021
PL10.03.2021
RO10.03.2021
RS10.03.2021
SE10.03.2021
SI10.03.2021
SK10.03.2021
SM10.03.2021
BG10.06.2021
NO10.06.2021
GR11.06.2021
IS10.07.2021
PT12.07.2021
IE10.10.2021
LU10.10.2021
BE31.10.2021
CH31.10.2021
LI31.10.2021
Former [2023/30]HU10.10.2014
AL10.03.2021
AT10.03.2021
CY10.03.2021
CZ10.03.2021
DK10.03.2021
EE10.03.2021
ES10.03.2021
FI10.03.2021
HR10.03.2021
IT10.03.2021
LT10.03.2021
LV10.03.2021
MC10.03.2021
NL10.03.2021
PL10.03.2021
RO10.03.2021
RS10.03.2021
SE10.03.2021
SI10.03.2021
SK10.03.2021
SM10.03.2021
BG10.06.2021
NO10.06.2021
GR11.06.2021
IS10.07.2021
PT12.07.2021
IE10.10.2021
LU10.10.2021
BE31.10.2021
CH31.10.2021
LI31.10.2021
Former [2023/29]HU10.10.2014
AL10.03.2021
AT10.03.2021
CZ10.03.2021
DK10.03.2021
EE10.03.2021
ES10.03.2021
FI10.03.2021
HR10.03.2021
IT10.03.2021
LT10.03.2021
LV10.03.2021
MC10.03.2021
NL10.03.2021
PL10.03.2021
RO10.03.2021
RS10.03.2021
SE10.03.2021
SI10.03.2021
SK10.03.2021
SM10.03.2021
BG10.06.2021
NO10.06.2021
GR11.06.2021
IS10.07.2021
PT12.07.2021
IE10.10.2021
LU10.10.2021
BE31.10.2021
CH31.10.2021
LI31.10.2021
Former [2022/48]AL10.03.2021
AT10.03.2021
CZ10.03.2021
DK10.03.2021
EE10.03.2021
ES10.03.2021
FI10.03.2021
HR10.03.2021
IT10.03.2021
LT10.03.2021
LV10.03.2021
MC10.03.2021
NL10.03.2021
PL10.03.2021
RO10.03.2021
RS10.03.2021
SE10.03.2021
SI10.03.2021
SK10.03.2021
SM10.03.2021
BG10.06.2021
NO10.06.2021
GR11.06.2021
IS10.07.2021
PT12.07.2021
IE10.10.2021
LU10.10.2021
BE31.10.2021
CH31.10.2021
LI31.10.2021
Former [2022/37]AL10.03.2021
AT10.03.2021
CZ10.03.2021
DK10.03.2021
EE10.03.2021
ES10.03.2021
FI10.03.2021
HR10.03.2021
IT10.03.2021
LT10.03.2021
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MC10.03.2021
NL10.03.2021
PL10.03.2021
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SE10.03.2021
SI10.03.2021
SK10.03.2021
SM10.03.2021
BG10.06.2021
NO10.06.2021
GR11.06.2021
IS10.07.2021
PT12.07.2021
LU10.10.2021
BE31.10.2021
CH31.10.2021
LI31.10.2021
Former [2022/35]AL10.03.2021
AT10.03.2021
CZ10.03.2021
DK10.03.2021
EE10.03.2021
ES10.03.2021
FI10.03.2021
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IT10.03.2021
LT10.03.2021
LV10.03.2021
MC10.03.2021
NL10.03.2021
PL10.03.2021
RO10.03.2021
RS10.03.2021
SE10.03.2021
SI10.03.2021
SK10.03.2021
SM10.03.2021
BG10.06.2021
NO10.06.2021
GR11.06.2021
IS10.07.2021
PT12.07.2021
LU10.10.2021
BE31.10.2021
Former [2022/33]AL10.03.2021
AT10.03.2021
CZ10.03.2021
DK10.03.2021
EE10.03.2021
ES10.03.2021
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GR11.06.2021
IS10.07.2021
PT12.07.2021
BE31.10.2021
Former [2022/23]AL10.03.2021
AT10.03.2021
CZ10.03.2021
DK10.03.2021
EE10.03.2021
ES10.03.2021
FI10.03.2021
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IT10.03.2021
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NL10.03.2021
PL10.03.2021
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RS10.03.2021
SE10.03.2021
SI10.03.2021
SK10.03.2021
SM10.03.2021
BG10.06.2021
NO10.06.2021
GR11.06.2021
IS10.07.2021
PT12.07.2021
Former [2022/13]AL10.03.2021
AT10.03.2021
CZ10.03.2021
DK10.03.2021
EE10.03.2021
ES10.03.2021
FI10.03.2021
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LT10.03.2021
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NL10.03.2021
PL10.03.2021
RO10.03.2021
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SE10.03.2021
SI10.03.2021
SK10.03.2021
SM10.03.2021
BG10.06.2021
NO10.06.2021
GR11.06.2021
PT12.07.2021
Former [2022/10]AL10.03.2021
AT10.03.2021
CZ10.03.2021
DK10.03.2021
EE10.03.2021
ES10.03.2021
FI10.03.2021
HR10.03.2021
LT10.03.2021
LV10.03.2021
NL10.03.2021
PL10.03.2021
RO10.03.2021
RS10.03.2021
SE10.03.2021
SK10.03.2021
SM10.03.2021
BG10.06.2021
NO10.06.2021
GR11.06.2021
PT12.07.2021
Former [2022/08]AL10.03.2021
AT10.03.2021
CZ10.03.2021
DK10.03.2021
EE10.03.2021
ES10.03.2021
FI10.03.2021
HR10.03.2021
LT10.03.2021
LV10.03.2021
NL10.03.2021
PL10.03.2021
RO10.03.2021
RS10.03.2021
SE10.03.2021
SK10.03.2021
SM10.03.2021
BG10.06.2021
NO10.06.2021
GR11.06.2021
IS10.07.2021
PT12.07.2021
Former [2022/07]AL10.03.2021
AT10.03.2021
CZ10.03.2021
EE10.03.2021
ES10.03.2021
FI10.03.2021
HR10.03.2021
LT10.03.2021
LV10.03.2021
NL10.03.2021
PL10.03.2021
RO10.03.2021
RS10.03.2021
SE10.03.2021
SK10.03.2021
SM10.03.2021
BG10.06.2021
NO10.06.2021
GR11.06.2021
IS10.07.2021
PT12.07.2021
Former [2021/52]AT10.03.2021
CZ10.03.2021
EE10.03.2021
ES10.03.2021
FI10.03.2021
HR10.03.2021
LT10.03.2021
LV10.03.2021
NL10.03.2021
PL10.03.2021
RO10.03.2021
RS10.03.2021
SE10.03.2021
SK10.03.2021
SM10.03.2021
BG10.06.2021
NO10.06.2021
GR11.06.2021
IS10.07.2021
PT12.07.2021
Former [2021/51]AT10.03.2021
CZ10.03.2021
EE10.03.2021
ES10.03.2021
FI10.03.2021
HR10.03.2021
LT10.03.2021
LV10.03.2021
NL10.03.2021
RO10.03.2021
RS10.03.2021
SE10.03.2021
SK10.03.2021
SM10.03.2021
BG10.06.2021
NO10.06.2021
GR11.06.2021
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PT12.07.2021
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SE10.03.2021
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BG10.06.2021
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CZ10.03.2021
EE10.03.2021
FI10.03.2021
HR10.03.2021
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NL10.03.2021
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SE10.03.2021
SM10.03.2021
BG10.06.2021
NO10.06.2021
GR11.06.2021
Former [2021/46]AT10.03.2021
FI10.03.2021
HR10.03.2021
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LV10.03.2021
NL10.03.2021
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SE10.03.2021
SM10.03.2021
BG10.06.2021
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GR11.06.2021
Former [2021/43]FI10.03.2021
HR10.03.2021
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LV10.03.2021
NL10.03.2021
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Former [2021/37]FI10.03.2021
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LT10.03.2021
LV10.03.2021
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Former [2021/36]FI10.03.2021
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NO10.06.2021
Documents cited:Search[XI]US2010120694  (SHAILUBHAI KUNWAR [US], et al) [X] 1-15 * claims 4-9 * * paragraph [0098] * * the whole document * [I] 1-15;
 [XY]US2010152118  (SHAILUBHAI KUNWAR [US]) [X] 1-15 * paragraphs [0025] , [0 80] , [ 114] , [0 86] , [0 83] , [0 84] , [0 85] * [Y] 1-15;
 [XI]WO2012037380  (SYNERGY PHARMACEUTICALS INC [US], et al) [X] 1-15 * the whole document * [I] 1-15;
 [Y]  - Anonymous, "Plecanatide Eases Chronic Constipation", (20130524), URL: http://www.medscape.com/viewarticle/804738, (20170203), XP055341895 [Y] 1-15 * the whole document *
International search[A]US2012220526  (SHAILUBHAI KUNWAR [US], et al);
 [X]US2012237593  (COMISKEY STEPHEN [US], et al);
by applicantUS3773919
 US4503030
 US4522811
 US4668506
 US4713244
 US4767628
 EP0326151
 WO9001329
 US4910021
 US4931279
 US5007790
 EP0467389
 US5108758
 US5134122
 US5175003
 US5192741
 US5236704
 WO9324150
 WO9406452
 WO9415587
 US5358502
 US5445832
 WO9704744
 US5609590
 US5612052
 WO9726015
 US5672659
 WO9740085
 WO9813029
 WO9825642
 US5840860
 JPH10324642
 US5866619
 US5877224
 US5893985
 US5912014
 US5922356
 US5952314
 US5968895
 US5972389
 US5980945
 US6011011
 US6086918
 WO0101964
 US6180608
 WO0112233
 US6234464
 WO0149249
 WO0149311
 WO0174175
 US6309633
 US2002019446
 US6368629
 WO0230398
 WO0238129
 WO0243767
 US6403130
 WO02058672
 WO02072075
 WO02072033
 WO02072034
 WO02074247
 US2002176841
 WO03007913
 US6531152
 US2003064105
 US2003068384
 US2003082575
 WO03035029
 WO03035041
 US2003108885
 WO03053401
 US2003138488
 US2003171296
 US6620422
 WO03075887
 WO03086297
 US2003216307
 US6667060
 WO03105812
 WO2004019872
 WO2004041195
 WO2004052339
 WO2004064769
 WO2004076632
 WO2004112711
 WO2005027878
 WO2005030182
 WO2005048998
 WO2005063156
 WO2005063206
 US2006019347
 WO2014151206
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.