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Extract from the Register of European Patents

EP About this file: EP3071040

EP3071040 - METHOD FOR SCALABLE SKELETAL MUSCLE LINEAGE SPECIFICATION AND CULTIVATION [Right-click to bookmark this link]
StatusPatent maintained as amended
Status updated on  25.11.2022
Database last updated on 19.07.2024
FormerThe patent has been granted
Status updated on  05.12.2019
FormerGrant of patent is intended
Status updated on  18.07.2019
FormerExamination is in progress
Status updated on  16.02.2018
Most recent event   Tooltip20.01.2023Change - lapse in a contracting state
State(s) deleted from list of lapses: NL		published on 22.02.2023  [2023/08]
Applicant(s)For all designated states
The Curators of the University of Missouri
316 University Hall
Columbia, MO 65211 / US
For all designated states
Upside Foods, Inc.
804 Heinz Avenue
Berkeley CA 94710 / US
[2021/35]
Former [2020/16]For all designated states
The Curators of the University of Missouri
316 University Hall
Columbia, MO 65211 / US
For all designated states
MEMPHIS MEATS, INC.
804 Heinz Avenue
Berkeley, CA 94710 / US
Former [2016/39]For all designated states
The Curators of the University of Missouri
316 University Hall
Columbia, MO 65211 / US
For all designated states
MEMPHIS MEATS, INC.
1933 Davis St.
Suite 312
San Leandro, CA 94577 / US
Inventor(s)01 / GENOVESE, Nicholas, J.
c/o Memphis Meats, Inc.
804 Heinz Avenue
Berkeley, CA 94710 / US
02 / ROBERTS, R., Michael
University of Missouri
240B Bond Life Science Center
Columbia, MO 65211 / US
03 / TELUGU, Bhanu, Prakash, V., L.
c/o Memphis Meats, Inc.
804 Heinz Avenue
Berkeley, CA 94710 / US
 [2020/16]
Former [2016/39]01 / GENOVESE, Nicholas, J.
1517 Hayden Street
Hayward, CA 94545 / US
02 / ROBERTS, R., Michael
University of Missouri
240B Bond Life Science Center
Columbia, MO 65211 / US
03 / TELUGU, Bhanu, Prakash, V., L.
University of Maryland - College Park
Dept. of Animal and Avian Sciences
College Park, MD 20742 / US
Representative(s)Mewburn Ellis LLP
Aurora Building
Counterslip
Bristol BS1 6BX / GB
[2022/52]
Former [2016/39]Loo, Chi Ching, et al
Albright IP Limited
County House
Bayshill Road
Cheltenham, Gloucestershire GL50 3BA / GB
Application number, filing date14858383.430.10.2014
[2016/39]
WO2014US63250
Priority number, dateUS201361962068P30.10.2013         Original published format: US 201361962068 P
[2016/39]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2015066377
Date:07.05.2015
Language:EN
[2015/18]
Type: A1 Application with search report 
No.:EP3071040
Date:28.09.2016
Language:EN
The application published by WIPO in one of the EPO official languages on 07.05.2015 takes the place of the publication of the European patent application.
[2016/39]
Type: B1 Patent specification 
No.:EP3071040
Date:01.01.2020
Language:EN
[2020/01]
Type: B2 New European patent specification 
No.:EP3071040
Date:28.12.2022
Language:EN
[2022/52]
Search report(s)International search report - published on:US07.05.2015
(Supplementary) European search report - dispatched on:EP19.05.2017
ClassificationIPC:A01N63/00, A01N65/00, A61K35/35, C12N5/10, A61K35/28, C12N5/077, A23L13/00, A61K35/545
[2017/25]
CPC:
C12N5/0658 (EP,IL,US); A23L13/00 (EP,IL,US); A61K35/28 (EP,IL);
A61K35/545 (EP,IL); C12N5/10 (EP,IL,US); A23V2002/00 (IL,US);
C12N2501/392 (EP,IL,US); C12N2501/40 (IL,US); C12N2501/415 (EP,IL,US);
C12N2501/60 (EP,IL,US); C12N2501/602 (IL,US); C12N2501/603 (EP,IL,US);
C12N2501/604 (EP,IL,US); C12N2501/72 (EP,IL,US); C12N2501/727 (EP,IL,US);
C12N2501/999 (EP,IL,US); C12N2506/02 (EP,IL,US); C12N2506/45 (EP,IL,US) (-)
Former IPC [2016/39]A01N63/00, A01N65/00, A61K35/35
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/39]
TitleGerman:VERFAHREN ZUR SKALIERBAREN SKELETTMUSKEL-STAMMZELLENSPEZIFIKATION UND -KULTIVIERUNG[2016/39]
English:METHOD FOR SCALABLE SKELETAL MUSCLE LINEAGE SPECIFICATION AND CULTIVATION[2016/39]
French:PROCÉDÉ DESTINÉ À SPÉCIFIER ET CULTIVER UNE LIGNÉE DE MUSCLE SQUELETTIQUE ÉVOLUTIVE[2016/39]
Entry into regional phase23.05.2016National basic fee paid 
23.05.2016Search fee paid 
23.05.2016Designation fee(s) paid 
23.05.2016Examination fee paid 
Examination procedure23.05.2016Examination requested  [2016/39]
18.12.2017Amendment by applicant (claims and/or description)
19.02.2018Despatch of a communication from the examining division (Time limit: M06)
28.09.2018Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
10.12.2018Reply to a communication from the examining division
19.07.2019Communication of intention to grant the patent
22.11.2019Fee for grant paid
22.11.2019Fee for publishing/printing paid
22.11.2019Receipt of the translation of the claim(s)
Divisional application(s)EP19220227.3   Application deemed to be withdrawn  : 01.07.2020
Opposition(s)Opponent(s)01  01.10.2020  05.10.2020  ADMISSIBLE
Gleiss Große Schrell und Partner mbB
Leitzstrasse 45
70469 Stuttgart / DE
Opponent's representative
Schrell, Andreas, et al, et al
Gleiss Große Schrell und Partner mbB
Patentanwälte Rechtsanwälte
Leitzstrasse 45
70469 Stuttgart / DE
 [2020/46]
13.10.2020Invitation to proprietor to file observations on the notice of opposition
22.02.2021Reply of patent proprietor to notice(s) of opposition
16.02.2022Legal effect of interlocutory decision in opposition
16.02.2022Date of oral proceedings
01.04.2022Despatch of interlocutory decision in opposition
01.04.2022Despatch of minutes of oral proceedings
22.08.2022Despatch of communication that the patent will be maintained as amended
17.11.2022Fee for printing new specification paid
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
10.12.2018Request for further processing filed
10.12.2018Full payment received (date of receipt of payment)
Request granted
20.12.2018Decision despatched
Fees paidRenewal fee
27.10.2016Renewal fee patent year 03
25.10.2017Renewal fee patent year 04
24.10.2018Renewal fee patent year 05
25.10.2019Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU30.10.2014
AL01.01.2020
AT01.01.2020
CY01.01.2020
CZ01.01.2020
DK01.01.2020
EE01.01.2020
FI01.01.2020
HR01.01.2020
LT01.01.2020
LV01.01.2020
MC01.01.2020
MK01.01.2020
MT01.01.2020
PL01.01.2020
RO01.01.2020
RS01.01.2020
SE01.01.2020
SI01.01.2020
SK01.01.2020
SM01.01.2020
TR01.01.2020
BG01.04.2020
NO01.04.2020
GR02.04.2020
IS01.05.2020
PT27.05.2020
GB30.10.2020
IE30.10.2020
LU30.10.2020
BE31.10.2020
CH31.10.2020
LI31.10.2020
[2023/08]
Former [2022/34]HU30.10.2014
AL01.01.2020
AT01.01.2020
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MK01.01.2020
MT01.01.2020
PL01.01.2020
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SK01.01.2020
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TR01.01.2020
BG01.04.2020
NO01.04.2020
GR02.04.2020
IS01.05.2020
PT27.05.2020
GB30.10.2020
IE30.10.2020
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CH31.10.2020
LI31.10.2020
NL01.11.2020
Former [2022/31]HU30.10.2014
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AT01.01.2020
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LT01.01.2020
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MK01.01.2020
MT01.01.2020
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SI01.01.2020
SK01.01.2020
SM01.01.2020
TR01.01.2020
BG01.04.2020
NO01.04.2020
GR02.04.2020
IS01.05.2020
PT27.05.2020
GB30.10.2020
IE30.10.2020
LU30.10.2020
BE31.10.2020
CH31.10.2020
FR31.10.2020
LI31.10.2020
NL01.11.2020
Former [2022/30]HU30.10.2014
AL01.01.2020
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CZ01.01.2020
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LT01.01.2020
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MC01.01.2020
MT01.01.2020
PL01.01.2020
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SI01.01.2020
SK01.01.2020
SM01.01.2020
TR01.01.2020
BG01.04.2020
NO01.04.2020
GR02.04.2020
IS01.05.2020
PT27.05.2020
GB30.10.2020
IE30.10.2020
LU30.10.2020
BE31.10.2020
CH31.10.2020
FR31.10.2020
LI31.10.2020
NL01.11.2020
Former [2022/27]HU30.10.2014
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PT27.05.2020
GB30.10.2020
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BG01.04.2020
NO01.04.2020
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IS01.05.2020
PT27.05.2020
GB30.10.2020
IE30.10.2020
LU30.10.2020
BE31.10.2020
CH31.10.2020
FR31.10.2020
LI31.10.2020
NL01.11.2020
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PT27.05.2020
GB30.10.2020
IE30.10.2020
LU30.10.2020
BE31.10.2020
CH31.10.2020
FR31.10.2020
LI31.10.2020
NL01.11.2020
DE01.05.2021
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MC01.01.2020
PL01.01.2020
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SM01.01.2020
BG01.04.2020
NO01.04.2020
GR02.04.2020
IS01.05.2020
PT27.05.2020
GB30.10.2020
LU30.10.2020
BE31.10.2020
CH31.10.2020
FR31.10.2020
LI31.10.2020
NL01.11.2020
DE01.05.2021
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BG01.04.2020
NO01.04.2020
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IS01.05.2020
PT27.05.2020
LU30.10.2020
BE31.10.2020
CH31.10.2020
FR31.10.2020
LI31.10.2020
NL01.11.2020
DE01.05.2021
Former [2021/36]AT01.01.2020
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BG01.04.2020
NO01.04.2020
GR02.04.2020
IS01.05.2020
PT27.05.2020
LU30.10.2020
BE31.10.2020
FR31.10.2020
NL01.11.2020
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MC01.01.2020
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SI01.01.2020
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SM01.01.2020
BG01.04.2020
NO01.04.2020
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IS01.05.2020
PT27.05.2020
LU30.10.2020
FR31.10.2020
NL01.11.2020
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PT27.05.2020
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NL01.11.2020
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SI01.01.2020
SK01.01.2020
SM01.01.2020
BG01.04.2020
NO01.04.2020
GR02.04.2020
IS01.05.2020
PT27.05.2020
LU30.10.2020
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HR01.01.2020
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PL01.01.2020
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BG01.04.2020
NO01.04.2020
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Documents cited:Search[X]US2013004466  (TREMBLAY JACQUES P [CA], et al) [X] 1,3,5,12,13,15 * the whole document * * claims 9-16 * * figures 8, 10; examples 8-10 *;
 [X]WO2013073246  (UNIV KYOTO [JP], et al) [X] 1-6,13,15 * page 3, paragraph 007 * * page 35, paragraph 0087 - page 51, paragraph 0115; figure 9 * * page 12, paragraph 0028 * * the whole document *;
 [T]  - NICHOLAS J. GENOVESE ET AL, "Enhanced Development of Skeletal Myotubes from Porcine Induced Pluripotent Stem Cells", SCIENTIFIC REPORTS, (20170206), vol. 7, doi:10.1038/srep41833, page 41833, XP055369888

DOI:   http://dx.doi.org/10.1038/srep41833
International search[X]EP0435617  (UNIV GEORGIA RES FOUND [US]);
 [Y]WO9309236  (BAYLOR COLLEGE MEDICINE [US]);
 [Y]US2011191871  (WALSH KENNETH [US], et al)
Examination   - MARK J POST ED - SERDAROGLU M, "Cultured meat from stem cells: Challenges and prospects", MEAT SCIENCE, ELSEVIER SCIENCE, GB, vol. 92, no. 3, doi:10.1016/J.MEATSCI.2012.04.008, ISSN 0309-1740, (20120403), pages 297 - 301, (20120411), XP028504027

DOI:   http://dx.doi.org/10.1016/j.meatsci.2012.04.008
OppositionUS2013004466
 WO2013073246
    - RINKEVICH, BARUCH, "Cell cultures from marine invertebrates: new insights for capturing endless sternness", Marine Biotechnology, (20110107), vol. 13, no. 3, doi:10.1007/s10126-010-9354-3, pages 345 - 354, XP019910939

DOI:   http://dx.doi.org/10.1007/s10126-010-9354-3
    - NOWAK-IMIALEK, MONIKA et al., "Pluripotent cells in farm animals: state of the art and future perspectives", Reproduction, Fertility and Development, (20120000), vol. 25, no. 1, pages 103 - 128, XP055738782

DOI:   http://dx.doi.org/10.1071/RD12265
    - BHAT, ZUHAIB FAYAZ et al., "Animal-free meat biofabrication", American Journal of Food Technology, (20110515), vol. 6, no. 6, pages 441 - 459, XP0557387824
    - GENOVESE, NICHOLAS J. et al., "Enhanced development of skeletal myotubes from porcine induced pluripotent stem cells", Scientific reports, (20170000), vol. 7, doi:10.1038/srep41833, page 41833, XP055369888

DOI:   http://dx.doi.org/10.1038/srep41833
    - MOLKENTIN, JEFFERY D. et al., "Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins", Cell, (19951229), vol. 83, no. 7, pages 1125 - 1136, XP055369889

DOI:   http://dx.doi.org/10.2337/diab.18.4.206
    - SCHNAPP, ESTHER et al., "Induced early expression of mrf4 but not myog rescues myogenesis in the myod/myf5 double-morphant zebrafish embryo", Journal of Cell Science, (20090215), vol. 122, no. 4, pages 481 - 488, XP055738790

DOI:   http://dx.doi.org/10.1242/jcs.038356
    - BLACK, BRIAN L. et al., "Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins", Annual review of cell and developmental biology, (19980000), vol. 14, no. 1, doi:10.1146/annurev.cellbio.14.1.167, pages 167 - 196, XP000981549

DOI:   http://dx.doi.org/10.1146/annurev.cellbio.14.1.167
    - CHEN, ZIRONG et al., "DNA methyltransferase inhibitor CDA-II inhibits myogenic differentiation", Biochemical and biophysical research communications, (20120600), vol. 422, no. 3, pages 522 - 526, XP055738792

DOI:   http://dx.doi.org/10.1016/j.bbrc.2012.05.068
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