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Extract from the Register of European Patents

EP About this file: EP2907525

EP2907525 - DIBENZOCYCLOOCTENE-COMPOUNDS FOR BIOORTHOGONAL REACTIONS [Right-click to bookmark this link]
Former [2015/34]Alkynes and methods of reacting alkynes with 1,3-dipole-functional compounds
[2017/50]
StatusNo opposition filed within time limit
Status updated on  22.03.2019
Database last updated on 08.06.2024
FormerThe patent has been granted
Status updated on  13.04.2018
FormerGrant of patent is intended
Status updated on  24.11.2017
FormerExamination is in progress
Status updated on  20.03.2017
FormerRequest for examination was made
Status updated on  25.11.2016
Most recent event   Tooltip10.07.2020Lapse of the patent in a contracting state
New state(s): CY, HU, IS		published on 12.08.2020  [2020/33]
Applicant(s)For all designated states
University Of Georgia Research Foundation, Inc.
Boyd Graduate Studies Research Center
Athens, GA 30602-7411 / US
[2015/34]
Inventor(s)01 / Boons, Geert-Jan
103 Georgetown Drive
Athens, GA 30605 / US
02 / Guo, Jun
Central China Normal University, College of Chem.
152 Luoyu Rd
Wuhan 430079 / CN
03 / Ning, Xinghai
1130 Stone Shoals Terrace
Watkinsville, GA 30677 / US
04 / Wolfert, Margaretha
103 Georgetown Drive
Athens, GA 30605 / US
 [2018/20]
Former [2015/34]01 / Boons, Geert-Jan
1321 Lake Wellbrook Drive
Georgia, 30606 Athens / US
02 / Guo, Jun
123 Benedict Court
Georgia, 30605 Athens / US
03 / Ning, Xinghai
2091 S. Milledge Avenue, Apt. A22
Georgia, 30605 Athens / US
04 / Wolfert, Margaretha
1321 Lake Wellbrook Drive
Georgia, 30606 Athens / US
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[2015/34]
Application number, filing date15156184.221.11.2008
[2015/34]
Priority number, dateUS2007000402121.11.2007         Original published format: US 4021
US2007000767414.12.2007         Original published format: US 7674
US2008013706125.07.2008         Original published format: US 137061
[2015/34]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP2907525
Date:19.08.2015
Language:EN
[2015/34]
Type: A3 Search report 
No.:EP2907525
Date:02.12.2015
Language:EN
[2015/49]
Type: B1 Patent specification 
No.:EP2907525
Date:16.05.2018
Language:EN
[2018/20]
Search report(s)(Supplementary) European search report - dispatched on:EP03.11.2015
ClassificationIPC:C07D249/16, C07D261/20, C07D271/12, C07D307/94, C07D311/90, C07H21/00, C07D495/04, C07K2/00, C07K14/00, A61K49/00, A61K47/54, A61K47/61, A61K47/62, A61K47/64, A61K47/69
[2017/49]
CPC:
A61K49/0021 (EP,CN,US); C07C35/37 (EP,CN,US); C07C251/58 (US);
A61K47/54 (EP,US); A61K47/542 (US); A61K47/61 (US);
A61K47/62 (US); A61K47/64 (US); A61K47/6803 (US);
A61K47/6921 (EP,CN,US); A61K49/0043 (EP,CN,US); A61K49/0052 (EP,CN,US);
A61P37/04 (EP); C07C211/42 (EP,CN,US); C07C251/44 (EP,CN,US);
C07C271/34 (US); C07C49/683 (EP,CN,US); C07D249/16 (EP,CN,US);
C07D261/20 (EP,CN,US); C07D271/12 (EP,CN,US); C07D307/94 (EP,CN,US);
C07D311/90 (EP,CN,US); C07D495/04 (EP,CN,US); C07H21/00 (EP,US);
C07K14/00 (US); C07K2/00 (US); G01N33/582 (US);
C07C2603/36 (EP,CN,US) (-)
Former IPC [2015/34]A61K47/48, A61K49/10, C07C35/37, C07C49/683, C07C211/42, C07C251/44, C07D249/18, C07D263/52, C07D271/12
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2016/28]
Former [2015/34]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
Extension statesAL31.05.2016
BA31.05.2016
MK31.05.2016
RS31.05.2016
TitleGerman:DIBENZOCYCLOOCTEN-VERBINDUNGEN FUER BIOORTHOGONALE REAKTIONEN[2017/50]
English:DIBENZOCYCLOOCTENE-COMPOUNDS FOR BIOORTHOGONAL REACTIONS[2018/20]
French:COMPOSÉS DIBENZOCYCLOOCTEN POUR DES RÉACTIONS BIOORTHOGONALES[2017/50]
Former [2015/34]ALKINE UND VERFAHREN ZUR REAKTION VON ALKINEN MIT 1,3-DIPOLFUNKTIONALEN VERBINDUNGEN
Former [2015/34]Alkynes and methods of reacting alkynes with 1,3-dipole-functional compounds
Former [2015/34]ALCYNES ET PROCÉDÉS DE RÉACTION D'ALCYNES AVEC DES COMPOSÉS 1,3-DIPOLAIRES FONCTIONNELS
Examination procedure08.09.2015Despatch of communication that the application is refused, reason: Examination on filing A.90(5) {1}
31.05.2016Amendment by applicant (claims and/or description)
31.05.2016Examination requested  [2016/28]
17.03.2017Despatch of a communication from the examining division (Time limit: M04)
26.07.2017Reply to a communication from the examining division
22.11.2017Communication of intention to grant the patent
03.04.2018Fee for grant paid
03.04.2018Fee for publishing/printing paid
03.04.2018Receipt of the translation of the claim(s)
Appeal following examination19.10.2015Appeal received
19.10.2015Statement of grounds filed
02.11.2015Interlocutory revision of appeal
Parent application(s)   TooltipEP08852196.8  / EP2222341
Opposition(s)19.02.2019No opposition filed within time limit [2019/17]
Fees paidRenewal fee
18.06.2015Renewal fee patent year 03
18.06.2015Renewal fee patent year 04
18.06.2015Renewal fee patent year 05
18.06.2015Renewal fee patent year 06
18.06.2015Renewal fee patent year 07
30.11.2015Renewal fee patent year 08
28.11.2016Renewal fee patent year 09
27.11.2017Renewal fee patent year 10
Opt-out from the exclusive  Tooltip
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU21.11.2008
AT16.05.2018
CY16.05.2018
CZ16.05.2018
EE16.05.2018
ES16.05.2018
FI16.05.2018
HR16.05.2018
IT16.05.2018
LT16.05.2018
LV16.05.2018
MC16.05.2018
PL16.05.2018
PT16.05.2018
RO16.05.2018
SI16.05.2018
SK16.05.2018
TR16.05.2018
BG16.08.2018
NO16.08.2018
GR17.08.2018
IS16.09.2018
IE21.11.2018
LU21.11.2018
MT21.11.2018
BE30.11.2018
CH30.11.2018
LI30.11.2018
[2020/32]
Former [2020/28]AT16.05.2018
CZ16.05.2018
EE16.05.2018
ES16.05.2018
FI16.05.2018
HR16.05.2018
IT16.05.2018
LT16.05.2018
LV16.05.2018
MC16.05.2018
PL16.05.2018
PT16.05.2018
RO16.05.2018
SI16.05.2018
SK16.05.2018
TR16.05.2018
BG16.08.2018
NO16.08.2018
GR17.08.2018
IE21.11.2018
LU21.11.2018
MT21.11.2018
BE30.11.2018
CH30.11.2018
LI30.11.2018
Former [2020/16]AT16.05.2018
CZ16.05.2018
EE16.05.2018
ES16.05.2018
FI16.05.2018
HR16.05.2018
IT16.05.2018
LT16.05.2018
LV16.05.2018
MC16.05.2018
PL16.05.2018
RO16.05.2018
SI16.05.2018
SK16.05.2018
TR16.05.2018
BG16.08.2018
NO16.08.2018
GR17.08.2018
IE21.11.2018
LU21.11.2018
MT21.11.2018
BE30.11.2018
CH30.11.2018
LI30.11.2018
Former [2020/08]AT16.05.2018
CZ16.05.2018
EE16.05.2018
ES16.05.2018
FI16.05.2018
HR16.05.2018
IT16.05.2018
LT16.05.2018
LV16.05.2018
MC16.05.2018
PL16.05.2018
RO16.05.2018
SI16.05.2018
SK16.05.2018
BG16.08.2018
NO16.08.2018
GR17.08.2018
IE21.11.2018
LU21.11.2018
MT21.11.2018
BE30.11.2018
CH30.11.2018
LI30.11.2018
Former [2019/51]AT16.05.2018
CZ16.05.2018
EE16.05.2018
ES16.05.2018
FI16.05.2018
HR16.05.2018
IT16.05.2018
LT16.05.2018
LV16.05.2018
MC16.05.2018
PL16.05.2018
RO16.05.2018
SI16.05.2018
SK16.05.2018
BG16.08.2018
NO16.08.2018
GR17.08.2018
IE21.11.2018
LU21.11.2018
BE30.11.2018
CH30.11.2018
LI30.11.2018
Former [2019/48]AT16.05.2018
CZ16.05.2018
EE16.05.2018
ES16.05.2018
FI16.05.2018
HR16.05.2018
IT16.05.2018
LT16.05.2018
LV16.05.2018
MC16.05.2018
PL16.05.2018
RO16.05.2018
SI16.05.2018
SK16.05.2018
BG16.08.2018
NO16.08.2018
GR17.08.2018
IE21.11.2018
LU21.11.2018
CH30.11.2018
LI30.11.2018
Former [2019/40]AT16.05.2018
CZ16.05.2018
EE16.05.2018
ES16.05.2018
FI16.05.2018
HR16.05.2018
IT16.05.2018
LT16.05.2018
LV16.05.2018
MC16.05.2018
PL16.05.2018
RO16.05.2018
SI16.05.2018
SK16.05.2018
BG16.08.2018
NO16.08.2018
GR17.08.2018
LU21.11.2018
CH30.11.2018
LI30.11.2018
Former [2019/34]AT16.05.2018
CZ16.05.2018
EE16.05.2018
ES16.05.2018
FI16.05.2018
HR16.05.2018
IT16.05.2018
LT16.05.2018
LV16.05.2018
MC16.05.2018
PL16.05.2018
RO16.05.2018
SI16.05.2018
SK16.05.2018
BG16.08.2018
NO16.08.2018
GR17.08.2018
LU21.11.2018
Former [2019/33]AT16.05.2018
CZ16.05.2018
EE16.05.2018
ES16.05.2018
FI16.05.2018
HR16.05.2018
IT16.05.2018
LT16.05.2018
LV16.05.2018
MC16.05.2018
PL16.05.2018
RO16.05.2018
SI16.05.2018
SK16.05.2018
BG16.08.2018
NO16.08.2018
GR17.08.2018
Former [2019/26]AT16.05.2018
CZ16.05.2018
EE16.05.2018
ES16.05.2018
FI16.05.2018
HR16.05.2018
IT16.05.2018
LT16.05.2018
LV16.05.2018
PL16.05.2018
RO16.05.2018
SI16.05.2018
SK16.05.2018
BG16.08.2018
NO16.08.2018
GR17.08.2018
Former [2019/11]AT16.05.2018
CZ16.05.2018
EE16.05.2018
ES16.05.2018
FI16.05.2018
HR16.05.2018
IT16.05.2018
LT16.05.2018
LV16.05.2018
PL16.05.2018
RO16.05.2018
SK16.05.2018
BG16.08.2018
NO16.08.2018
GR17.08.2018
Former [2019/10]AT16.05.2018
CZ16.05.2018
EE16.05.2018
ES16.05.2018
FI16.05.2018
HR16.05.2018
LT16.05.2018
LV16.05.2018
PL16.05.2018
RO16.05.2018
SK16.05.2018
BG16.08.2018
NO16.08.2018
GR17.08.2018
Former [2019/09]EE16.05.2018
ES16.05.2018
FI16.05.2018
HR16.05.2018
LT16.05.2018
LV16.05.2018
BG16.08.2018
NO16.08.2018
GR17.08.2018
Former [2018/52]ES16.05.2018
FI16.05.2018
HR16.05.2018
LT16.05.2018
LV16.05.2018
BG16.08.2018
NO16.08.2018
GR17.08.2018
Former [2018/51]ES16.05.2018
FI16.05.2018
HR16.05.2018
LT16.05.2018
LV16.05.2018
BG16.08.2018
NO16.08.2018
Former [2018/50]ES16.05.2018
FI16.05.2018
HR16.05.2018
LT16.05.2018
BG16.08.2018
NO16.08.2018
Former [2018/47]ES16.05.2018
FI16.05.2018
LT16.05.2018
NO16.08.2018
Documents cited:Search[A]WO2007039858  (KONINKL PHILIPS ELECTRONICS NV [NL], et al) [A] 1 * the whole document *;
 [A]  - PRESCHER JENNIFER A ET AL, "Chemistry in living systems", NATURE CHEMICAL BIOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US, (20050601), vol. 1, no. 1, ISSN 1552-4450, pages 13 - 21, XP002410570 [A] 1 * page 17: "Strain-promoted Cycloaddition" *

DOI:   http://dx.doi.org/10.1038/nchembio0605-13
 [XP]  - X NING ET AL., "Visualizing Metabolically Labeled Glycoconjugates of Living Cells by Copper-Free and Fast Huisgen Cycloaddition", ANGEW CHEM INT ED, (20080214), vol. 47, pages 2253 - 2255, XP002522848 [XP] 1-8 * the whole document *

DOI:   http://dx.doi.org/10.1002/ANIE.200705456
by applicant   - BINDER ET AL., MACROMOL. RAPID COMMUN, (2008), vol. 29, pages 952 - 981
    - BASKIN ET AL., QSAR COMB. SCI., (2007), vol. 26, pages 1211 - 1219
    - CODELLI ET AL., J. AM. CHEM. SOC., (2008), vol. 130, pages 11486 - 11493
    - JOHNSON ET AL., CHEM. COMMUN., (2008), pages 3064 - J066
    - SLETTEN ET AL., ORGANIC LETTERS, (2008), vol. 10, pages 3097 - 3099
    - LAUGHLIN ET AL., SCIENCE, (2008), vol. 320, pages 664 - 667
    - NISHIYAMA, ADV. POLYM. SCI., (2006), vol. 193, pages 67 - 101
    - GAUCHER ET AL., J.CONTROL. RELEASE, (2005), vol. 109, pages 169 - 188
    - CHOI ET AL., J. DISPERSION SCI. TECH., (2003), vol. 24, pages 475 - 487
    - LAVASANIFAR ET AL., ADV. DRUG DELIVERY REV., (2002), vol. 54, pages 169 - 190
    - ROSIER ET AL., ADV. DRUG DELIVERY REV., (2001), vol. 53, pages 95 - 108
    - KOLB; SHARPLESS, DRUG DISCOVERY TODAY, (2003), vol. 8, pages 1128 - 1137
    - DEDOLA ET AL., ORG. BIOMOL. CHEM., (2007), vol. 5, pages 1006 - 1017
    - MOSES; MOORHOUSE, CHEM. SOC. REV., (2007), vol. 36, pages 1249 - 1262
    - NANDIVADA ET AL., ADV.MATER., (2007), vol. 19, pages 2197 - 2208
    - WU; FOKIN, ALDRICHIMICA ACTA, (2007), vol. 40, pages 7 - 17
    - ROSTOVTSEV ET AL., ANGEW. CHEM., (2002), vol. 114, pages 2708 - 2711
    - ROSTOVTSEV ET AL., ANGEW. CHEM. INT. ED., (2002), vol. 41, pages 2596 - 2599
    - TORNOE ET AL., J.ORG. CHEM., (2002), vol. 67, pages 3057 - 3064
    - CHIN ET AL., SCIENCE, (2003), vol. 301, pages 964 - 967
    - WANG ET AL., J. AM. CHEM. SOC., (2003), vol. 125, pages 3192 - 3193
    - KHO ET AL., PROC.NATL.ACAD. SCI. USA, (2004), vol. 101, pages 12479 - 12484
    - GIERLICH ET AL., ORG. LETT., (2006), vol. 8, pages 3639 - 3642
    - LINK ET AL., PROC. NATL. ACAD. SCI. USA, (2006), vol. 103, pages 10180 - 10185
    - SPEERS ET AL., J. AM. CHEM. SOC., (2003), vol. 125, pages 4686 - 4687
    - SUN ET AL., BIOCONJUGATE CHEM, (2006), vol. 17, pages 52 - 57
    - PRESCHER; BERTOZZI, NAT. CHEM. BIOL., (2005), vol. 1, pages 13 - 21
    - HANSON ET AL., J. AM. CHEM. SOC., (2007), vol. 129, pages 7266 - 7267
    - SIVAKUMAR ET AL., ORG. LETT, (2004), vol. 6, pages 4603 - 4606
    - LINK; TIRREL, J. AM. CHEM. SOC., (2003), vol. 125, pages 11164 - 11165
    - TUMER ET AL., J. AM. CHEM. SOC., (1973), vol. 95, pages 790 - 792
    - AGARD ET AL., J. AM. CHEM. SOC., (2004), vol. 126, pages 15046 - 15047
    - VANBERKEL ET AL., CHEM-BIOCHEM, (2007), vol. 8, pages 1504 - 1508
    - TURNER, J.AM. CHEM. SOC., (1973), vol. 95, pages 790 - 792
    - AGARD ET AL., ACS CHEM. BIOL., (2006), vol. 1, pages 644 - 648
    - JUNG ET AL., J.ORG. CHEM., (1978), vol. 43, pages 3698 - 3701
    - JUNG; MILLER, J. AM. CHEM. SOC., (1981), vol. 103, pages 1984 - 1992
    - SEITZ ET AL., ANGEW. CHEM., (1969), vol. 81, pages 427 - 428
    - SEITZ ET AL., ANGEW. CHEM. INT. ED. ENGL., (1969), vol. 8, pages 447 - 448
    - LUCHANSKY; BERTOZZI, CHEM-BIOCHEM, (2004), vol. 5, pages 1706 - 1709
    - BASKIN ET AL., PROC. NATL. ACAD. SCI. USA, (2007), vol. 104, pages 16793 - 16797
    - DEDOLA ET AL., ORG. BIOMOL. CHEM., (2007), vol. 5, page 1006
    - KOLB; SHARPLESS, DRUG DIS. TODAY, (2003), vol. 8, page 1128
    - MOSES; MOORHOUSE, CHEM. SOC. REV., (2007), vol. 36, page 1249
    - NANDIVADA ET AL., ADV. MATER., (2007), vol. 19, page 2197
    - WU; FOKIN, ALDRICHIMICA ACTA, (2007), vol. 40, page 7
    - AGARD ET AL., ACS CHEM. BIOL., (2006), vol. 1, page 644
    - CHIN ET AL., SCIENCE, (2003), vol. 301, page 964
    - GICRLICH ET AL., ORG. LETT., (2006), vol. 8, page 3639
    - KHO ET AL., PROC. NAT/. ACAD. SCI., (2004), vol. 101, page 12479
    - LINK ET AL., PROC. NATL.ACAD.SCI., (2006), vol. 103, page 10180
    - ; WANG ET AL., J. AM. CHEM. SOC., (2003), vol. 125, page 3192
    - SPEERS ET AL., J. AM. CHEM. SOC., (2003), vol. 125, page 4686
    - SUN ET AL., BIOCONJUGATE CHEM., (2006), vol. 17, page 52
    - PRESCHER; BERTOZZI, NAT. CHEM. BIOL., (2005), vol. 1, page 13
    - HANSON ET AL., J. AM. CHEM. SOC., (2007), vol. 129, page 7266
    - SIVAKUMAR ET AL., ORG. LETT., (2004), vol. 6, page 4603
    - TOO, EXPERT REV. PROTEOMICS, (2007), vol. 4, page 603
    - BANTSCHEFF ET AL., ANAL. BIOANAL. CHEM, (2007), vol. 389, page 1017
    - LAU ET AL., PROTEAMICS, (2007), vol. 7, page 2787
    - HANSON ET AL., J. AAM. CHEM. SOC., (2007), vol. 129, page 7266
    - TOO, EXPERT REV. PROFEOMICS, (2007), vol. 4, page 603
    - BANTSCHEFF, ANAL. BIOANAL. CHON., (2007), vol. 389, page 1017
    - LAU ET AL., PROTEOMICS, (2007), vol. 7, page 2787
    - CHAFFINS, S.; BRETTREICH, M.; WUDL, F., SYNTHESIS, (2002), pages 1191 - 1194
    - DICKEN ET AL., J. ORG. CHEM., (1982), vol. 47, pages 2047 - 2051
    - INOUYE ET AL., BULL. CHEM. SOC. JPN., (1983), vol. 56, pages 3541 - 3542
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.