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Extract from the Register of European Patents

EP About this file: EP3018216

EP3018216 - RECURRENT GENE FUSIONS IN PROSTATE CANCER [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  19.07.2019
Database last updated on 28.05.2024
FormerThe patent has been granted
Status updated on  10.08.2018
FormerGrant of patent is intended
Status updated on  15.03.2018
FormerExamination is in progress
Status updated on  04.08.2017
FormerRequest for examination was made
Status updated on  18.11.2016
Most recent event   Tooltip23.07.2021Lapse of the patent in a contracting state
New state(s): MT
published on 25.08.2021  [2021/34]
Applicant(s)For all designated states
The Regents of The University of Michigan
1600 Huron Parkway, 2nd Floor
Ann Arbor, MI 48109-2590 / US
[2016/19]
Inventor(s)01 / Chinnaiyan, Arul M.
51300 Plymouth Valley Drive
Plymouth, MI 48170 / US
02 / Tomlins, Scott
793 Fletch St.
Ann Arbor, MI 48103 / US
 [2016/19]
Representative(s)Mewburn Ellis LLP
Aurora Building
Counterslip
Bristol BS1 6BX / GB
[N/P]
Former [2016/19]Walton, Seán Malcolm
Mewburn Ellis LLP
City Tower
40 Basinghall Street
London EC2V 5DE / GB
Application number, filing date15185944.403.07.2008
[2016/19]
Priority number, dateUS2007082555206.07.2007         Original published format: US 825552
[2016/19]
Previously filed application, dateEP2012017958803.07.2008
[2016/19]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP3018216
Date:11.05.2016
Language:EN
[2016/19]
Type: B1 Patent specification 
No.:EP3018216
Date:12.09.2018
Language:EN
[2018/37]
Search report(s)(Supplementary) European search report - dispatched on:EP11.04.2016
ClassificationIPC:C12Q1/68
[2016/19]
CPC:
C12Q1/6886 (EP,US); C12Q2600/106 (EP); C12Q2600/118 (EP);
C12Q2600/136 (EP); C12Q2600/156 (EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2016/51]
Former [2016/19]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:REZIDIVIERENDE GENFUSIONEN BEI PROSTATAKREBS[2016/19]
English:RECURRENT GENE FUSIONS IN PROSTATE CANCER[2016/19]
French:FUSIONS DE GÈNE RÉCURRENTES DANS LE CANCER DE LA PROSTATE[2016/19]
Examination procedure18.09.2015Date on which the examining division has become responsible
11.11.2016Examination requested  [2016/51]
13.01.2017Despatch of communication that the application is deemed to be withdrawn, reason: reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report not received in time
03.03.2017Amendment by applicant (claims and/or description)
02.08.2017Despatch of a communication from the examining division (Time limit: M02)
04.10.2017Reply to a communication from the examining division
16.03.2018Communication of intention to grant the patent
17.07.2018Fee for grant paid
17.07.2018Fee for publishing/printing paid
17.07.2018Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP08772418.3  / EP2167689
EP12179588.4  / EP2604701
Opposition(s)13.06.2019No opposition filed within time limit [2019/34]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
03.03.2017Request for further processing filed
03.03.2017Full payment received (date of receipt of payment)
Request granted
15.03.2017Decision despatched
Fees paidRenewal fee
06.10.2015Renewal fee patent year 03
06.10.2015Renewal fee patent year 04
06.10.2015Renewal fee patent year 05
06.10.2015Renewal fee patent year 06
06.10.2015Renewal fee patent year 07
06.10.2015Renewal fee patent year 08
27.07.2016Renewal fee patent year 09
27.07.2017Renewal fee patent year 10
27.07.2018Renewal fee patent year 11
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU03.07.2008
AT12.09.2018
CY12.09.2018
CZ12.09.2018
DK12.09.2018
EE12.09.2018
ES12.09.2018
FI12.09.2018
HR12.09.2018
IT12.09.2018
LT12.09.2018
LV12.09.2018
MC12.09.2018
MT12.09.2018
NL12.09.2018
PL12.09.2018
RO12.09.2018
SE12.09.2018
SI12.09.2018
SK12.09.2018
TR12.09.2018
BG12.12.2018
NO12.12.2018
GR13.12.2018
IS12.01.2019
PT12.01.2019
[2021/34]
Former [2021/32]HU03.07.2008
AT12.09.2018
CY12.09.2018
CZ12.09.2018
DK12.09.2018
EE12.09.2018
ES12.09.2018
FI12.09.2018
HR12.09.2018
IT12.09.2018
LT12.09.2018
LV12.09.2018
MC12.09.2018
NL12.09.2018
PL12.09.2018
RO12.09.2018
SE12.09.2018
SI12.09.2018
SK12.09.2018
TR12.09.2018
BG12.12.2018
NO12.12.2018
GR13.12.2018
IS12.01.2019
PT12.01.2019
Former [2021/26]AT12.09.2018
CY12.09.2018
CZ12.09.2018
DK12.09.2018
EE12.09.2018
ES12.09.2018
FI12.09.2018
HR12.09.2018
IT12.09.2018
LT12.09.2018
LV12.09.2018
MC12.09.2018
NL12.09.2018
PL12.09.2018
RO12.09.2018
SE12.09.2018
SI12.09.2018
SK12.09.2018
TR12.09.2018
BG12.12.2018
NO12.12.2018
GR13.12.2018
IS12.01.2019
PT12.01.2019
Former [2020/17]AT12.09.2018
CZ12.09.2018
DK12.09.2018
EE12.09.2018
ES12.09.2018
FI12.09.2018
HR12.09.2018
IT12.09.2018
LT12.09.2018
LV12.09.2018
MC12.09.2018
NL12.09.2018
PL12.09.2018
RO12.09.2018
SE12.09.2018
SI12.09.2018
SK12.09.2018
TR12.09.2018
BG12.12.2018
NO12.12.2018
GR13.12.2018
IS12.01.2019
PT12.01.2019
Former [2020/14]AT12.09.2018
CZ12.09.2018
DK12.09.2018
EE12.09.2018
ES12.09.2018
FI12.09.2018
HR12.09.2018
IT12.09.2018
LT12.09.2018
LV12.09.2018
MC12.09.2018
NL12.09.2018
PL12.09.2018
RO12.09.2018
SE12.09.2018
SI12.09.2018
SK12.09.2018
BG12.12.2018
NO12.12.2018
GR13.12.2018
IS12.01.2019
PT12.01.2019
Former [2019/37]AT12.09.2018
CZ12.09.2018
DK12.09.2018
EE12.09.2018
ES12.09.2018
FI12.09.2018
HR12.09.2018
IT12.09.2018
LT12.09.2018
LV12.09.2018
NL12.09.2018
PL12.09.2018
RO12.09.2018
SE12.09.2018
SI12.09.2018
SK12.09.2018
BG12.12.2018
NO12.12.2018
GR13.12.2018
IS12.01.2019
PT12.01.2019
Former [2019/34]AT12.09.2018
CZ12.09.2018
DK12.09.2018
EE12.09.2018
ES12.09.2018
FI12.09.2018
HR12.09.2018
IT12.09.2018
LT12.09.2018
LV12.09.2018
NL12.09.2018
PL12.09.2018
RO12.09.2018
SE12.09.2018
SK12.09.2018
BG12.12.2018
NO12.12.2018
GR13.12.2018
IS12.01.2019
PT12.01.2019
Former [2019/26]AT12.09.2018
CZ12.09.2018
EE12.09.2018
ES12.09.2018
FI12.09.2018
HR12.09.2018
IT12.09.2018
LT12.09.2018
LV12.09.2018
NL12.09.2018
PL12.09.2018
RO12.09.2018
SE12.09.2018
SK12.09.2018
BG12.12.2018
NO12.12.2018
GR13.12.2018
IS12.01.2019
PT12.01.2019
Former [2019/23]AT12.09.2018
CZ12.09.2018
EE12.09.2018
ES12.09.2018
FI12.09.2018
HR12.09.2018
IT12.09.2018
LT12.09.2018
LV12.09.2018
NL12.09.2018
PL12.09.2018
RO12.09.2018
SE12.09.2018
SK12.09.2018
BG12.12.2018
NO12.12.2018
GR13.12.2018
IS12.01.2019
Former [2019/22]CZ12.09.2018
FI12.09.2018
HR12.09.2018
IT12.09.2018
LT12.09.2018
LV12.09.2018
NL12.09.2018
PL12.09.2018
RO12.09.2018
SE12.09.2018
BG12.12.2018
NO12.12.2018
GR13.12.2018
IS12.01.2019
Former [2019/21]FI12.09.2018
HR12.09.2018
IT12.09.2018
LT12.09.2018
LV12.09.2018
NL12.09.2018
SE12.09.2018
BG12.12.2018
NO12.12.2018
GR13.12.2018
IS12.01.2019
Former [2019/20]FI12.09.2018
HR12.09.2018
LT12.09.2018
LV12.09.2018
NL12.09.2018
SE12.09.2018
BG12.12.2018
NO12.12.2018
GR13.12.2018
Former [2019/12]FI12.09.2018
HR12.09.2018
LT12.09.2018
LV12.09.2018
SE12.09.2018
BG12.12.2018
NO12.12.2018
GR13.12.2018
Former [2019/11]FI12.09.2018
HR12.09.2018
LT12.09.2018
SE12.09.2018
BG12.12.2018
NO12.12.2018
GR13.12.2018
Former [2019/10]FI12.09.2018
LT12.09.2018
SE12.09.2018
BG12.12.2018
NO12.12.2018
GR13.12.2018
Former [2019/08]FI12.09.2018
LT12.09.2018
NO12.12.2018
Former [2019/07]LT12.09.2018
Documents cited:Search[X]WO2007033187  (UNIV MICHIGAN [US], et al) [X] 1-10 * claims 1-15,24,34 *;
 [XP]  - HELGESON BETH E ET AL, "Characterization of TMPRSS2:ETV5 and SLC45A3:ETV5 gene fusions in prostate cancer.", CANCER RESEARCH 1 JAN 2008, (20080101), vol. 68, no. 1, ISSN 1538-7445, pages 73 - 80, XP007906828 [XP] 1-10 * page 73, column l, paragraph 4 * * figures 3a,3c *

DOI:   http://dx.doi.org/10.1158/0008-5472.CAN-07-5352
 [A]  - MEHRA ROHIT ET AL, "Comprehensive assessment of TMPRSS2 and ETS family gene aberrations in clinically localized prostate cancer.", MODERN PATHOLOGY : AN OFFICIAL JOURNAL OF THE UNITED STATES AND CANADIAN ACADEMY OF PATHOLOGY, INC MAY 2007, (200705), vol. 20, no. 5, ISSN 0893-3952, pages 538 - 544, XP007906804 [A] 1-10 * the whole document *

DOI:   http://dx.doi.org/10.1038/modpathol.3800769
 [AD]  - TOMLINS SCOTT A ET AL, "Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, US, WASHINGTON, DC, (20051028), vol. 310, no. 5748, ISSN 0036-8075, pages 644 - 648, XP002464140 [AD] 1-10 * the whole document *

DOI:   http://dx.doi.org/10.1126/science.1117679
 [A]  - CHANGMENG CAI ET AL, "ETV1 is a novel androgen receptor-regulated gene that mediates prostate cancer cell invasion", MOLECULAR ENDOCRINOLOGY, THE ENDOCRINE SOCIETY, US, vol. 21, no. 8, doi:10.1210/ME.2006-0480, ISSN 0888-8809, (20070515), pages 1835 - 1846, (20070515), XP008162981 [A] 1-10 * the whole document *

DOI:   http://dx.doi.org/10.1210/me.2006-0480
 [A]  - VELASCO ANNE MARIE ET AL, "Identification and validation of novel androgen-regulated genes in prostate cancer", ENDOCRINOLOGY, THE ENDOCRINE SOCIETY, US, (20040801), vol. 145, no. 8, doi:10.1210/EN.2004-0311, ISSN 0013-7227, pages 3913 - 3924, XP002617640 [A] 1-10 * the whole document *

DOI:   http://dx.doi.org/10.1210/en.2004-0311
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