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Extract from the Register of European Patents

EP About this file: EP3102194

EP3102194 - BETA-SUBSTITUTED GAMMA-AMINO ACIDS AND ANALOGS AS CHEMOTHERAPEUTIC AGENTS [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  06.12.2019
Database last updated on 13.07.2024
FormerExamination is in progress
Status updated on  11.06.2019
FormerRequest for examination was made
Status updated on  11.11.2016
Most recent event   Tooltip06.12.2019Withdrawal of applicationpublished on 08.01.2020  [2020/02]
Applicant(s)For all designated states
Quadriga Biosciences, Inc.
1111 West El Camino Real
Suite 109-234
Sunnyvale, California 94087 / US
[2016/50]
Inventor(s)01 / JANDELEIT, Bernd
1111 West El Camino Real
Suite 109-234
Sunnyvale, California 94087 / US
02 / FISCHER, Wolf-Nicolas
1111 West El Camino Real
Suite 109-234
Sunnyvale, California 94087 / US
03 / KOLLER, Kerry J.
1111 West El Camino Real
Suite 109-234
Sunnyvale, California 94087 / US
 [2016/50]
Representative(s)Nieuwenhuys, William Francis
Marks & Clerk LLP
15 Fetter Lane
London EC4A 1BW / GB
[N/P]
Former [2016/50]Nieuwenhuys, William Francis
Marks & Clerk LLP 90 Long Acre London
WC2E 9RA / GB
Application number, filing date15705866.003.02.2015
[2016/50]
WO2015US14299
Priority number, dateUS201461935235P03.02.2014         Original published format: US 201461935235 P
[2016/50]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2015117146
Date:06.08.2015
Language:EN
[2015/31]
Type: A1 Application with search report 
No.:EP3102194
Date:14.12.2016
Language:EN
The application published by WIPO in one of the EPO official languages on 06.08.2015 takes the place of the publication of the European patent application.
[2016/50]
Search report(s)International search report - published on:EP06.08.2015
ClassificationIPC:A61K31/197, A61K31/41, A61K31/662, C07C271/46, C07C309/66, C07C229/42, C07D257/04, C07D237/30, C07C239/20, C07C251/04, C07F9/30, A61P35/00
[2016/50]
CPC:
A61K31/197 (EP,US); A61K31/41 (EP,US); A61K31/662 (EP,US);
A61K47/542 (EP,US); A61P1/02 (EP); A61P1/04 (EP);
A61P1/16 (EP); A61P1/18 (EP); A61P11/00 (EP);
A61P11/02 (EP); A61P13/02 (EP); A61P13/08 (EP);
A61P13/10 (EP); A61P13/12 (EP); A61P15/00 (EP);
A61P17/00 (EP); A61P19/00 (EP); A61P21/00 (EP);
A61P25/00 (EP); A61P27/02 (EP); A61P35/00 (EP);
A61P35/02 (EP); A61P5/00 (EP); A61P9/00 (EP);
C07C229/08 (US); C07C229/42 (EP,US); C07C237/30 (EP,US);
C07C239/18 (EP,US); C07C239/20 (EP,US); C07C271/46 (EP,US);
C07C309/69 (EP,US); C07D257/04 (EP,US); C07F9/3264 (EP,US);
C07F9/48 (US); C07F9/4816 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/50]
TitleGerman:BETA-SUBSTITUIERTE GAMMA-AMINOSÄUREN UND ANALOGA ALS CHEMOTHERAPEUTIKA[2016/50]
English:BETA-SUBSTITUTED GAMMA-AMINO ACIDS AND ANALOGS AS CHEMOTHERAPEUTIC AGENTS[2016/50]
French:ACIDES GAMMA-AMINÉS BÊTA-SUBSTITUÉS ET ANALOGUES EN TANT QU'AGENTS CHIMIOTHÉRAPEUTIQUES[2016/50]
Entry into regional phase03.08.2016National basic fee paid 
03.08.2016Designation fee(s) paid 
03.08.2016Examination fee paid 
Examination procedure03.08.2016Examination requested  [2016/50]
03.08.2016Date on which the examining division has become responsible
20.03.2017Amendment by applicant (claims and/or description)
14.06.2019Despatch of a communication from the examining division (Time limit: M06)
02.12.2019Application withdrawn by applicant  [2020/02]
Fees paidRenewal fee
30.08.2017Renewal fee patent year 03
14.02.2018Renewal fee patent year 04
13.02.2019Renewal fee patent year 05
Penalty fee
Additional fee for renewal fee
28.02.201703   M06   Fee paid on   30.08.2017
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Cited inInternational search[X]WO2004054566  (WARNER LAMBERT CO [US], et al) [X] 1-3,9,12-21,28,31-33,40-43,45,58-61,67,68 * the whole document * * page 18, line 29 - page 19, line 3 * * page 20, lines 3-14 * * page 20, line 24 - page 21, line 20 *;
 [X]WO2012011125  (CONNEXIOS LIFE SCIENCES PVT LTD [IN], et al) [X] 1-3,9,12-18,21,22,25,28-30,33,41-43,63-70 * the whole document * * example 93 *;
 [X]  - DOMKIENE, V. ET AL, "Toxicity and antineoplastic activity of alkylating compounds derived from L-histidine", CA, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, (1974), Database accession no. 1974:128258, URL: STN, XP002738278 [X] 1-9,16-18,21,22,25-28,40-43,63-70 * abstract *
 [X]  - DAGIENE, M. ET AL, "Carcinogenic peptides. X. Derivatives of N.alpha.-bis(2-chloroethyl)aminophenylacetyl-L-histidine", CA, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, Database accession no. 1970:13046, URL: STN, XP002738279 [X] 1-9,16-18,21,22,25-28,40-43,63-66 * abstract *
 [X]  - DOMKIENE, V. ET AL, "Comparative studies of alkylating peptide like histidine derivatives", HCAPLUS, Database accession no. 1972:483626, URL: STN, XP002738280 [X] 1-9,16-18,21,22,25-28,40-43,63-66 * abstract *
 [X]  - FENG XU ET AL, "Discovery of a novel potent GABAreceptor agonist", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, AMSTERDAM, NL, vol. 21, no. 21, doi:10.1016/J.BMCL.2011.08.006, ISSN 0960-894X, (20110801), pages 6582 - 6585, (20110817), XP028308820 [X] 1-3,9,12-22,25-30,33,63-68 * the whole document * * table 1 *

DOI:   http://dx.doi.org/10.1016/j.bmcl.2011.08.006
 [A]  - PAULAITYTE, N. ET AL, "Development of a spectrophotometric method for the determination of alkylating agents with .gamma.-(4-nitrobenzyl)pyridine", CA, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, Database accession no. 1974:22450, URL: STN, XP002738281 [A] 1-72 * abstract *
 [A]  - AGADZHANYAN, TS. E. ET AL, "Biologically active polymers. VI. Synthesis of poly- and copolypeptides containing cytotoxic groups", ARMYANSKII KHIMICHESKII ZHURNAL , 28(8), 662-6 CODEN: AYKZAN; ISSN: 0515-9628, (1975), XP008175885 [A] 1-72
Examination   - BENAKLI K ET AL, "PREPARATION OF NEW CHLORAMBUCIL ANALOGS BY BIS-SRN1 METHODOLOGY", SYNTHETIC COMMUNICATIONS, TAYLOR & FRANCIS INC, PHILADELPHIA, PA; US, (20020101), vol. 32, no. 12, doi:10.1081/SCC-120004080, ISSN 0039-7911, pages 1859 - 1865, XP001114918

DOI:   http://dx.doi.org/10.1081/SCC-120004080
by applicantUS3235594
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 US4339443
 US5015644
 US5602273
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 US5959113
 US6313312
 WO02066410
 US6518289
 US6818787
 WO2005110416
 US6972341
 US7109239
 WO2007021937
 US7227028
 WO2008021369
 US2008045534
 WO2008031594
 US7399785
 WO2008117175
 WO2010122089
 US8168617
 US8344028
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