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Extract from the Register of European Patents

EP About this file: EP3104860

EP3104860 - PHARMACEUTICAL COMPOUNDS AS CHK1 INHIBITORS [Right-click to bookmark this link]
Former [2016/51]PHARMACEUTICAL COMPOUNDS
[2019/39]
StatusNo opposition filed within time limit
Status updated on  05.11.2021
Database last updated on 03.10.2024
FormerThe patent has been granted
Status updated on  27.11.2020
FormerGrant of patent is intended
Status updated on  22.07.2020
FormerExamination is in progress
Status updated on  24.06.2020
FormerGrant of patent is intended
Status updated on  25.02.2020
FormerExamination is in progress
Status updated on  24.01.2020
FormerGrant of patent is intended
Status updated on  24.09.2019
FormerExamination is in progress
Status updated on  07.12.2018
FormerRequest for examination was made
Status updated on  18.11.2016
Most recent event   Tooltip06.09.2024Lapse of the patent in a contracting state
New state(s): MT
published on 09.10.2024 [2024/41]
Applicant(s)For all designated states
Sentinel Oncology Limited
181 Science Park
Milton Road
Cambridge
Cambridgeshire CB4 0GJ / GB
[2020/47]
Former [2019/19]For all designated states
Seattle Genetics, Inc.
21823 30th Drive, S.E.
Bothell, WA 98021 / US
Former [2016/51]For all designated states
Cascadian Therapeutics, Inc.
2601 Fourth Avenue, Suite 500
Seattle, WA 98121 / US
Inventor(s)01 / BOYLE, Robert George
c/o Sentinel Oncology Limited
Suite 52
23 Cambridge Science Park
Cambridge, UK CB4 0EY / GB
02 / WALKER, David Winter
c/o Sentinel Oncology Limited
Suite 52
23 Cambridge Science Park
Cambridge, UK CB4 0EY / GB
03 / BOYCE, Richard Justin
c/o Sentinel Oncology Limited
Suite 52
23 Cambridge Science Park
Cambridge, UK CB4 0EY / GB
04 / PETERSON, Scott
Cascadian Therapeutics, Inc.
2601 Fourth Avenue
Suite 500
Seattle, WA 98121 / US
05 / FAROUZ, Francine
Cascadian Therapeutics, Inc.
2601 Fourth Avenue
Suite 500
Seattle, WA 98121 / US
06 / VO, Cong Hung
Cascadian Therapeutics, Inc.
2601 Fourth Avenue
Suite 500
Seattle, WA 98121 / US
 [2019/43]
Former [2016/51]01 / BOYLE, Robert George
C/o Sentinel Oncology Limited
Suite 52
23 Cambridge Science Park
Cambridge, UK CB4 0EY / GB
02 / WALKER, David Winter
c/o Sentinel Oncology Limited
Suite 52
23 Cambridge Science Park
Cambridge, UK CB4 0EY / GB
03 / BOYCE, Richard Justin
c/o Sentinel Oncology Limited
Suite 52
23 Cambridge Science Park
Cambridge, UK CB4 0EY / GB
04 / PETERSON, Scott
Cascadian Therapeutics, Inc.
2601 Fourth Avenue
Suite 500
Seattle, WA 98121 / US
05 / FAROUZ, Francine
Cascadian Therapeutics, Inc.
2601 Fourth Avenue
Suite 500
Seattle, WA 98121 / US
06 / VO, Cong Hung
Cascadian Therapeutics, Inc.
2601 Fourth Avenue
Suite 500
Seattle, WA 98121 / US
Representative(s)Hutchins, Michael Richard, et al
Schlich
9 St Catherine's Road
Littlehampton, West Sussex BN17 5HS / GB
[2016/51]
Application number, filing date15746362.109.02.2015
[2016/51]
WO2015US15030
Priority number, dateGB2014000227710.02.2014         Original published format: GB 201402277
US201462083687P24.11.2014         Original published format: US 201462083687 P
[2016/51]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2015120390
Date:13.08.2015
Language:EN
[2015/32]
Type: A1 Application with search report 
No.:EP3104860
Date:21.12.2016
Language:EN
The application published by WIPO in one of the EPO official languages on 13.08.2015 takes the place of the publication of the European patent application.
[2016/51]
Type: B1 Patent specification 
No.:EP3104860
Date:30.12.2020
Language:EN
[2020/53]
Search report(s)International search report - published on:US13.08.2015
(Supplementary) European search report - dispatched on:EP13.07.2017
ClassificationIPC:A61K31/4965, A61K31/497, C07D403/12, A61P35/00
[2017/33]
CPC:
A61K31/497 (EP,IL,KR,RU,US); A61K31/4155 (EP,KR,RU,US); C07D403/12 (EP,IL,KR,RU,US);
A61K31/454 (EP,IL,RU,US); A61K31/4545 (IL); A61K31/5377 (EP,IL,RU,US);
A61K31/551 (EP,US); A61K31/5513 (IL); A61K31/661 (RU);
A61K45/06 (EP,KR,RU,US); A61P35/00 (EP,RU); A61P35/02 (EP);
A61P43/00 (EP); C07D401/10 (EP,RU,US); C07D401/14 (EP,IL,KR,RU,US);
C07D403/04 (IL); C07D403/14 (EP,IL,KR,RU,US); C07D405/14 (EP,IL,KR,RU,US);
C07D413/14 (EP,IL,KR,RU,US); A61K2300/00 (KR) (-)
C-Set:
A61K31/4155, A61K2300/00 (EP,US);
A61K31/497, A61K2300/00 (US,EP)
Former IPC [2016/51]A61K31/4965, A61K31/497, C07D403/12
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/51]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:PHARMAZEUTISCHE VERBINDUNGEN ALS CHK1-INHIBITOREN[2019/39]
English:PHARMACEUTICAL COMPOUNDS AS CHK1 INHIBITORS[2019/39]
French:COMPOSÉS PHARMACEUTIQUES COMME INHIBITEURS DE CHK1[2019/39]
Former [2016/51]PHARMAZEUTISCHE VERBINDUNGEN
Former [2016/51]PHARMACEUTICAL COMPOUNDS
Former [2016/51]COMPOSÉS PHARMACEUTIQUES
Entry into regional phase31.08.2016National basic fee paid 
31.08.2016Search fee paid 
31.08.2016Designation fee(s) paid 
31.08.2016Examination fee paid 
Examination procedure09.12.2015Request for preliminary examination filed
International Preliminary Examining Authority: US
31.08.2016Examination requested  [2016/51]
31.08.2016Date on which the examining division has become responsible
09.02.2018Amendment by applicant (claims and/or description)
07.12.2018Despatch of a communication from the examining division (Time limit: M04)
10.04.2019Reply to a communication from the examining division
25.09.2019Communication of intention to grant the patent
22.01.2020Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
26.02.2020Communication of intention to grant the patent
24.06.2020Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
23.07.2020Communication of intention to grant the patent
17.11.2020Fee for grant paid
17.11.2020Fee for publishing/printing paid
17.11.2020Receipt of the translation of the claim(s)
Divisional application(s)EP20207986.9  / EP3811944
Opposition(s)01.10.2021No opposition filed within time limit [2021/49]
Fees paidRenewal fee
10.02.2017Renewal fee patent year 03
14.02.2018Renewal fee patent year 04
27.02.2019Renewal fee patent year 05
20.02.2020Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU09.02.2015
AL30.12.2020
AT30.12.2020
CY30.12.2020
CZ30.12.2020
DK30.12.2020
EE30.12.2020
ES30.12.2020
FI30.12.2020
HR30.12.2020
IT30.12.2020
LT30.12.2020
LV30.12.2020
MC30.12.2020
MK30.12.2020
MT30.12.2020
NL30.12.2020
PL30.12.2020
RO30.12.2020
RS30.12.2020
SE30.12.2020
SI30.12.2020
SK30.12.2020
SM30.12.2020
LU09.02.2021
BG30.03.2021
NO30.03.2021
GR31.03.2021
IS30.04.2021
PT30.04.2021
[2024/41]
Former [2024/22]HU09.02.2015
AL30.12.2020
AT30.12.2020
CY30.12.2020
CZ30.12.2020
DK30.12.2020
EE30.12.2020
ES30.12.2020
FI30.12.2020
HR30.12.2020
IT30.12.2020
LT30.12.2020
LV30.12.2020
MC30.12.2020
MK30.12.2020
NL30.12.2020
PL30.12.2020
RO30.12.2020
RS30.12.2020
SE30.12.2020
SI30.12.2020
SK30.12.2020
SM30.12.2020
LU09.02.2021
BG30.03.2021
NO30.03.2021
GR31.03.2021
IS30.04.2021
PT30.04.2021
Former [2023/33]HU09.02.2015
AL30.12.2020
AT30.12.2020
CY30.12.2020
CZ30.12.2020
DK30.12.2020
EE30.12.2020
ES30.12.2020
FI30.12.2020
HR30.12.2020
IT30.12.2020
LT30.12.2020
LV30.12.2020
MC30.12.2020
NL30.12.2020
PL30.12.2020
RO30.12.2020
RS30.12.2020
SE30.12.2020
SI30.12.2020
SK30.12.2020
SM30.12.2020
LU09.02.2021
BG30.03.2021
NO30.03.2021
GR31.03.2021
IS30.04.2021
PT30.04.2021
Former [2023/30]HU09.02.2015
AL30.12.2020
AT30.12.2020
CY30.12.2020
CZ30.12.2020
DK30.12.2020
EE30.12.2020
ES30.12.2020
FI30.12.2020
HR30.12.2020
IT30.12.2020
LT30.12.2020
LV30.12.2020
MC30.12.2020
NL30.12.2020
PL30.12.2020
RO30.12.2020
RS30.12.2020
SE30.12.2020
SI30.12.2020
SK30.12.2020
LU09.02.2021
BG30.03.2021
NO30.03.2021
GR31.03.2021
IS30.04.2021
PT30.04.2021
Former [2023/27]HU09.02.2015
AL30.12.2020
AT30.12.2020
CZ30.12.2020
DK30.12.2020
EE30.12.2020
ES30.12.2020
FI30.12.2020
HR30.12.2020
IT30.12.2020
LT30.12.2020
LV30.12.2020
MC30.12.2020
NL30.12.2020
PL30.12.2020
RO30.12.2020
RS30.12.2020
SE30.12.2020
SI30.12.2020
SK30.12.2020
LU09.02.2021
BG30.03.2021
NO30.03.2021
GR31.03.2021
IS30.04.2021
PT30.04.2021
Former [2022/23]AL30.12.2020
AT30.12.2020
CZ30.12.2020
DK30.12.2020
EE30.12.2020
ES30.12.2020
FI30.12.2020
HR30.12.2020
IT30.12.2020
LT30.12.2020
LV30.12.2020
MC30.12.2020
NL30.12.2020
PL30.12.2020
RO30.12.2020
RS30.12.2020
SE30.12.2020
SI30.12.2020
SK30.12.2020
LU09.02.2021
BG30.03.2021
NO30.03.2021
GR31.03.2021
IS30.04.2021
PT30.04.2021
Former [2022/13]AL30.12.2020
AT30.12.2020
CZ30.12.2020
DK30.12.2020
EE30.12.2020
ES30.12.2020
FI30.12.2020
HR30.12.2020
IT30.12.2020
LT30.12.2020
LV30.12.2020
MC30.12.2020
NL30.12.2020
PL30.12.2020
RO30.12.2020
RS30.12.2020
SE30.12.2020
SI30.12.2020
SK30.12.2020
LU09.02.2021
BG30.03.2021
NO30.03.2021
GR31.03.2021
PT30.04.2021
Former [2022/10]AL30.12.2020
AT30.12.2020
CZ30.12.2020
DK30.12.2020
EE30.12.2020
ES30.12.2020
FI30.12.2020
HR30.12.2020
IT30.12.2020
LT30.12.2020
LV30.12.2020
MC30.12.2020
NL30.12.2020
PL30.12.2020
RO30.12.2020
RS30.12.2020
SE30.12.2020
SK30.12.2020
LU09.02.2021
BG30.03.2021
NO30.03.2021
GR31.03.2021
PT30.04.2021
Former [2021/51]AL30.12.2020
AT30.12.2020
CZ30.12.2020
DK30.12.2020
EE30.12.2020
ES30.12.2020
FI30.12.2020
HR30.12.2020
IT30.12.2020
LT30.12.2020
LV30.12.2020
MC30.12.2020
NL30.12.2020
PL30.12.2020
RO30.12.2020
RS30.12.2020
SE30.12.2020
SK30.12.2020
LU09.02.2021
BG30.03.2021
NO30.03.2021
GR31.03.2021
IS30.04.2021
PT30.04.2021
Former [2021/49]AL30.12.2020
AT30.12.2020
CZ30.12.2020
DK30.12.2020
EE30.12.2020
FI30.12.2020
HR30.12.2020
IT30.12.2020
LT30.12.2020
LV30.12.2020
MC30.12.2020
NL30.12.2020
PL30.12.2020
RO30.12.2020
RS30.12.2020
SE30.12.2020
SK30.12.2020
LU09.02.2021
BG30.03.2021
NO30.03.2021
GR31.03.2021
IS30.04.2021
PT30.04.2021
Former [2021/48]AL30.12.2020
AT30.12.2020
CZ30.12.2020
EE30.12.2020
FI30.12.2020
HR30.12.2020
IT30.12.2020
LT30.12.2020
LV30.12.2020
MC30.12.2020
NL30.12.2020
PL30.12.2020
RO30.12.2020
RS30.12.2020
SE30.12.2020
SK30.12.2020
LU09.02.2021
BG30.03.2021
NO30.03.2021
GR31.03.2021
IS30.04.2021
PT30.04.2021
Former [2021/47]AL30.12.2020
AT30.12.2020
CZ30.12.2020
EE30.12.2020
FI30.12.2020
HR30.12.2020
LT30.12.2020
LV30.12.2020
MC30.12.2020
NL30.12.2020
PL30.12.2020
RO30.12.2020
RS30.12.2020
SE30.12.2020
SK30.12.2020
LU09.02.2021
BG30.03.2021
NO30.03.2021
GR31.03.2021
IS30.04.2021
PT30.04.2021
Former [2021/45]AL30.12.2020
AT30.12.2020
CZ30.12.2020
EE30.12.2020
FI30.12.2020
HR30.12.2020
LT30.12.2020
LV30.12.2020
MC30.12.2020
NL30.12.2020
PL30.12.2020
RO30.12.2020
RS30.12.2020
SE30.12.2020
SK30.12.2020
BG30.03.2021
NO30.03.2021
GR31.03.2021
IS30.04.2021
PT30.04.2021
Former [2021/42]AT30.12.2020
CZ30.12.2020
EE30.12.2020
FI30.12.2020
HR30.12.2020
LT30.12.2020
LV30.12.2020
MC30.12.2020
NL30.12.2020
PL30.12.2020
RO30.12.2020
RS30.12.2020
SE30.12.2020
SK30.12.2020
BG30.03.2021
NO30.03.2021
GR31.03.2021
IS30.04.2021
PT30.04.2021
Former [2021/41]AT30.12.2020
CZ30.12.2020
EE30.12.2020
FI30.12.2020
HR30.12.2020
LT30.12.2020
LV30.12.2020
MC30.12.2020
NL30.12.2020
PL30.12.2020
RO30.12.2020
RS30.12.2020
SE30.12.2020
SK30.12.2020
BG30.03.2021
NO30.03.2021
GR31.03.2021
PT30.04.2021
Former [2021/39]AT30.12.2020
CZ30.12.2020
EE30.12.2020
FI30.12.2020
HR30.12.2020
LT30.12.2020
LV30.12.2020
NL30.12.2020
PL30.12.2020
RO30.12.2020
RS30.12.2020
SE30.12.2020
SK30.12.2020
BG30.03.2021
NO30.03.2021
GR31.03.2021
PT30.04.2021
Former [2021/37]AT30.12.2020
CZ30.12.2020
EE30.12.2020
FI30.12.2020
HR30.12.2020
LT30.12.2020
LV30.12.2020
NL30.12.2020
RO30.12.2020
RS30.12.2020
SE30.12.2020
SK30.12.2020
BG30.03.2021
NO30.03.2021
GR31.03.2021
PT30.04.2021
Former [2021/36]CZ30.12.2020
EE30.12.2020
FI30.12.2020
HR30.12.2020
LT30.12.2020
LV30.12.2020
NL30.12.2020
RO30.12.2020
RS30.12.2020
SE30.12.2020
SK30.12.2020
BG30.03.2021
NO30.03.2021
GR31.03.2021
PT30.04.2021
Former [2021/35]CZ30.12.2020
FI30.12.2020
HR30.12.2020
LT30.12.2020
LV30.12.2020
NL30.12.2020
RO30.12.2020
RS30.12.2020
SE30.12.2020
SK30.12.2020
BG30.03.2021
NO30.03.2021
GR31.03.2021
PT30.04.2021
Former [2021/34]CZ30.12.2020
FI30.12.2020
HR30.12.2020
LT30.12.2020
LV30.12.2020
NL30.12.2020
RS30.12.2020
SE30.12.2020
BG30.03.2021
NO30.03.2021
GR31.03.2021
PT30.04.2021
Former [2021/33]FI30.12.2020
HR30.12.2020
LT30.12.2020
LV30.12.2020
RS30.12.2020
SE30.12.2020
BG30.03.2021
NO30.03.2021
GR31.03.2021
PT30.04.2021
Former [2021/28]FI30.12.2020
HR30.12.2020
LV30.12.2020
RS30.12.2020
SE30.12.2020
BG30.03.2021
NO30.03.2021
GR31.03.2021
Former [2021/24]FI30.12.2020
LV30.12.2020
RS30.12.2020
SE30.12.2020
BG30.03.2021
NO30.03.2021
GR31.03.2021
Former [2021/23]FI30.12.2020
LV30.12.2020
RS30.12.2020
SE30.12.2020
NO30.03.2021
GR31.03.2021
Former [2021/22]FI30.12.2020
RS30.12.2020
NO30.03.2021
Former [2021/20]FI30.12.2020
Documents cited:Search[XYI]WO2005009435  (PFIZER [US], et al);
 [Y]WO2010077758  (LILLY CO ELI [US], et al);
International search[Y]WO2010077758  (LILLY CO ELI [US], et al);
 [Y]US2013065900  (BOYLE ROBERT GEORGE [GB], et al);
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.