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Extract from the Register of European Patents

EP About this file: EP3119795

EP3119795 - GEMCITABINE ANALOGS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  15.03.2019
Database last updated on 02.09.2024
FormerRequest for examination was made
Status updated on  23.12.2016
FormerThe international publication has been made
Status updated on  09.11.2016
Most recent event   Tooltip15.03.2019Application deemed to be withdrawnpublished on 17.04.2019  [2019/16]
Applicant(s)For all designated states
NUCORION PHARMACEUTICALS, INC.
2711 Centerville Road, Suite 400
Willmington, DE 19808 / US
[2017/04]
Inventor(s)01 / TAGGART, David, J.
243 N. Stanwood Road
Columbus, OH 43209 / US
02 / CAO, Sheng
139 E. Fairmount Avenue
Milwaukee, WI 53217 / US
03 / SUO, Zucai
8120 Holyrood Court
Dublin, OH 43017 / US
 [2017/04]
Representative(s)Harris, Jennifer Lucy, et al
Kilburn & Strode LLP
Lacon London
84 Theobalds Road
London WC1X 8NL / GB
[N/P]
Former [2017/04]Harris, Jennifer Lucy, et al
Kilburn & Strode LLP 20 Red Lion Street
London WC1R 4PJ / GB
Application number, filing date15758660.327.02.2015
[2017/04]
WO2015US18184
Priority number, dateUS201461947050P03.03.2014         Original published format: US 201461947050 P
[2017/04]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2015134334
Date:11.09.2015
Language:EN
[2015/36]
Type: A1 Application with search report 
No.:EP3119795
Date:25.01.2017
Language:EN
The application published by WIPO in one of the EPO official languages on 11.09.2015 takes the place of the publication of the European patent application.
[2017/04]
Search report(s)International search report - published on:AU11.09.2015
(Supplementary) European search report - dispatched on:EP12.02.2018
ClassificationIPC:C07H19/06, C07H19/11, C07H19/10, A61K31/7068, A61P31/22, A61P31/20, A61P31/18, A61P31/14, A61P35/00, A61K45/06
[2017/49]
CPC:
C07H19/06 (EP,US); A61K45/06 (EP,US); A61P31/14 (EP);
A61P31/18 (EP); A61P31/20 (EP); A61P31/22 (EP);
A61P35/00 (EP); C07H19/10 (EP,US); C07H19/11 (EP,US);
A61K31/706 (EP,US); A61K31/7064 (EP,US); A61K31/7068 (EP,US);
Y02A50/30 (EP,US) (-)
Former IPC [2017/04]C07H19/11, C07H19/10, C07H19/06, A61K31/7068, A61P31/22, A61P31/20, A61P31/18, A61P31/14, A61P35/00
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/04]
TitleGerman:GEMCITABIN-ANALOGA[2017/04]
English:GEMCITABINE ANALOGS[2017/04]
French:ANALOGUES DE GEMCITABINE[2017/04]
Entry into regional phase21.09.2016National basic fee paid 
21.09.2016Search fee paid 
21.09.2016Designation fee(s) paid 
21.09.2016Examination fee paid 
Examination procedure21.09.2016Examination requested  [2017/04]
21.09.2016Date on which the examining division has become responsible
30.05.2017Amendment by applicant (claims and/or description)
12.09.2018Application deemed to be withdrawn, date of legal effect  [2019/16]
17.10.2018Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2019/16]
Fees paidRenewal fee
10.02.2017Renewal fee patent year 03
14.02.2018Renewal fee patent year 04
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Documents cited:Search[YA]WO2013142525  (ALIOS BIOPHARMA INC [US]) [Y] 1,2,4,6-8,14-18 * Claims, in particular claims 1-2, 86 and 155 and examples * [A] 5;
 [YA]WO2012040126  (ALIOS BIOPHARMA INC [US], et al) [Y] 1,2,4,6-8,14-18 * Claims, in particular claims 1, 52 and 64-83 and examples * [A] 5;
 [A]WO2006065525  (LILLY CO ELI [US], et al) [A] 1,2,4-8,14-18 * Claims 1 and 6-10 *;
 [YPA]WO2014074725  (OHIO STATE INNOVATION FOUNDATION [US]) [YP] 1,2,4,6-8,14-18 * Claims, in particular claims 1, 76 and 87; Examples * [A] 5;
 [E]WO2015081133  (IDENIX PHARMACEUTICALS INC [US]) [E] 1,2,4-8,14-18 * Claims, in particular claims 1, 3, 44-47; Examples *
 [A]  - WU WEIDONG ET AL, "Synthesis and biological activity of a gemcitabine phosphoramidate prodrug", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, vol. 50, no. 15, doi:10.1021/JM070269U, ISSN 0022-2623, (20070726), pages 3743 - 3746, (20070629), XP002474645 [A] 1,2,4-8,14-18 * Whole document, in particular compound 6 in scheme 2 *

DOI:   http://dx.doi.org/10.1021/jm070269u
 [YA]  - CUIRONG ZHAO ET AL, "Synthesis and Biological Evaluation of Oral Prodrugs Based on the Structure of Gemcitabine", CHEMICAL BIOLOGY & DRUG DESIGN., GB, (20120925), vol. 80, no. 3, doi:10.1111/j.1747-0285.2012.01422.x, ISSN 1747-0277, pages 479 - 488, XP055289724 [Y] 1,2,4,6-8,14-18 * Whole document, in particular Figure 1 and compound 5a in Table 1 * [A] 5

DOI:   http://dx.doi.org/10.1111/j.1747-0285.2012.01422.x
International search[A]WO2013142525  (ALIOS BIOPHARMA INC [US]) [A] 1-48 * see Examples 24, 38 and 108 pages 141, 163 and 250; Formulas (I) and (II) paragraph [0084]; paragraph [0194] *;
 [A]WO2012040126  (ALIOS BIOPHARMA INC [US], et al) [A] 1-48 * Examples 14, 44, 55, 68 and table 7 pages 154, 181, 192 and 218-231; Formula (I) paragraph [0087]; paragraphs [0149]-[0152] *;
 [PX]WO2014145207  (OHIO STATE INNOVATION FOUNDATION [US]) [PX] 25, 26, 28b, 29a and 30-48 * see page 50 2nd row 1st compound, page 51 4th row 2nd compound, and page 53 2nd row 2nd compound; paragraph [00220], [00225] and [00232]; paragraphs [00262]; paragraphs [00239]-[00253] and [00296]-[00297] *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.