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Extract from the Register of European Patents

EP About this file: EP3174978

EP3174978 - PROTEIN WITH DEXTRAN-SACCHARASE ACTIVITY, AND USES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  17.07.2020
Database last updated on 03.09.2024
FormerThe patent has been granted
Status updated on  09.08.2019
FormerGrant of patent is intended
Status updated on  13.05.2019
FormerExamination is in progress
Status updated on  08.12.2017
FormerRequest for examination was made
Status updated on  15.06.2017
FormerThe international publication has been made
Status updated on  13.12.2016
Most recent event   Tooltip08.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 10.08.2022  [2022/32]
Applicant(s)For all designated states
Institut National des Sciences Appliquées de Toulouse
135 avenue de Rangueil
31077 Toulouse Cedex 4 / FR
For all designated states
Institut national de recherche pour l'agriculture, l'alimentation et l'environnement
147 Rue de l'Université
75007 Paris / FR
For all designated states
Centre National de la Recherche Scientifique
3, rue Michel-Ange
75016 Paris / FR
For all designated states
Université Paul Sabatier Toulouse III
118 route de Narbonne
31400 Toulouse / FR
[N/P]
Former [2020/24]For all designated states
Institut National des Sciences Appliquées de Toulouse
135 avenue de Rangueil
31077 Toulouse Cedex 4 / FR
For all designated states
Institut national de recherche pour l'agriculture, l'alimentation et l'environnement
147 rue de l'Université
75007 Paris / FR
For all designated states
Centre National de la Recherche Scientifique
3, rue Michel-Ange
75016 Paris / FR
For all designated states
Université Paul Sabatier Toulouse III
118 route de Narbonne
31400 Toulouse / FR
Former [2017/23]For all designated states
Institut National des Sciences Appliquées de Toulouse
135 avenue de Rangueil
31077 Toulouse Cedex 4 / FR
For all designated states
Institut National De La Recherche Agronomique
147, rue de l'Université
75007 Paris / FR
For all designated states
Centre National de la Recherche Scientifique
3, rue Michel-Ange
75016 Paris / FR
For all designated states
Université Paul Sabatier Toulouse III
118 route de Narbonne
31400 Toulouse / FR
Inventor(s)01 / VUILLEMIN, Marlène
Heslegårdsvej 8, 3-4
2900 Hellerup / DK
02 / CLAVERIE, Marion
4 Rue Sully
F-64800 Benejacq / FR
03 / MOULIS, Claire
Lazières
F-31290 Viellevigne / FR
04 / REMAUD-SIMEON, Magali
1 Rue Benjamin Charrié
F-31520 Ramonville-Saint-Agne / FR
05 / MONSAN, Pierre
22 Chemin de la Gravette
F-31700 Mondonville / FR
06 / SEVERAC, Etienne
13 Avenue de Gasgogne
F-31820 Pibrac / FR
07 / FONTAGNE-FAUCHER, Catherine
L'Haouré
Chemin de Beaupuy
F-32600 L'Isle Jourdain / FR
 [2017/23]
Representative(s)Plasseraud IP
104 Rue de Richelieu
CS92104
75080 Paris Cedex 02 / FR
[N/P]
Former [2019/37]Cabinet Plasseraud
66, rue de la Chaussée d'Antin
75440 Paris Cedex 09 / FR
Former [2017/23]Cabinet Plasseraud
66 rue de la Chaussée d'Antin
75440 Paris Cedex 09 / FR
Application number, filing date15759857.421.07.2015
[2017/23]
WO2015FR52002
Priority number, dateFR2014005726428.07.2014         Original published format: FR 1457264
[2017/23]
Filing languageFR
Procedural languageFR
PublicationType: A1 Application with search report
No.:WO2016016544
Date:04.02.2016
Language:FR
[2016/05]
Type: A1 Application with search report 
No.:EP3174978
Date:07.06.2017
Language:FR
The application published by WIPO in one of the EPO official languages on 04.02.2016 takes the place of the publication of the European patent application.
[2017/23]
Type: B1 Patent specification 
No.:EP3174978
Date:11.09.2019
Language:FR
[2019/37]
Search report(s)International search report - published on:EP04.02.2016
ClassificationIPC:C12N9/10, C12P19/08, C12P19/18, A61K8/73, A61K47/36, A61K31/721, C08B37/02, A23L29/269
[2019/20]
CPC:
C12N9/1051 (EP,US); A23L29/273 (EP,US); A61K31/721 (EP,US);
A61K47/36 (US); A61K8/73 (US); C08B37/0021 (US);
C12P19/08 (EP,US); C12P19/18 (EP,US); C12Y204/01005 (EP,US);
A23V2002/00 (US) (-)
Former IPC [2017/23]C12N9/10, C12P19/08, C12P19/18
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/23]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
TitleGerman:PROTEIN MIT DEXTRANSACCHARASEAKTIVITÄT UND VERWENDUNGEN[2017/23]
English:PROTEIN WITH DEXTRAN-SACCHARASE ACTIVITY, AND USES[2017/23]
French:PROTEINE A ACTIVITE DEXTRANE-SACCHARASE ET APPLICATIONS[2017/23]
Entry into regional phase13.12.2016National basic fee paid 
13.12.2016Designation fee(s) paid 
13.12.2016Examination fee paid 
Examination procedure13.12.2016Amendment by applicant (claims and/or description)
13.12.2016Examination requested  [2017/23]
13.12.2016Date on which the examining division has become responsible
12.12.2017Despatch of a communication from the examining division (Time limit: M06)
11.06.2018Reply to a communication from the examining division
07.08.2018Despatch of a communication from the examining division (Time limit: M06)
03.01.2019Reply to a communication from the examining division
14.05.2019Communication of intention to grant the patent
07.06.2019Fee for grant paid
07.06.2019Fee for publishing/printing paid
07.06.2019Receipt of the translation of the claim(s)
Opposition(s)15.06.2020No opposition filed within time limit [2020/34]
Fees paidRenewal fee
24.05.2017Renewal fee patent year 03
27.07.2018Renewal fee patent year 04
30.07.2019Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAL11.09.2019
AT11.09.2019
CY11.09.2019
CZ11.09.2019
DK11.09.2019
EE11.09.2019
FI11.09.2019
HR11.09.2019
LT11.09.2019
LV11.09.2019
MC11.09.2019
MK11.09.2019
MT11.09.2019
PL11.09.2019
RO11.09.2019
RS11.09.2019
SI11.09.2019
SK11.09.2019
SM11.09.2019
TR11.09.2019
BG11.12.2019
GR12.12.2019
IS12.01.2020
[2022/32]
Former [2022/27]AL11.09.2019
AT11.09.2019
CY11.09.2019
CZ11.09.2019
DK11.09.2019
EE11.09.2019
FI11.09.2019
HR11.09.2019
LT11.09.2019
LV11.09.2019
MC11.09.2019
MT11.09.2019
PL11.09.2019
RO11.09.2019
RS11.09.2019
SI11.09.2019
SK11.09.2019
SM11.09.2019
TR11.09.2019
BG11.12.2019
GR12.12.2019
IS12.01.2020
Former [2021/15]AL11.09.2019
AT11.09.2019
CZ11.09.2019
DK11.09.2019
EE11.09.2019
FI11.09.2019
HR11.09.2019
LT11.09.2019
LV11.09.2019
MC11.09.2019
PL11.09.2019
RO11.09.2019
RS11.09.2019
SI11.09.2019
SK11.09.2019
SM11.09.2019
BG11.12.2019
GR12.12.2019
IS12.01.2020
Former [2020/37]AL11.09.2019
AT11.09.2019
CZ11.09.2019
DK11.09.2019
EE11.09.2019
FI11.09.2019
HR11.09.2019
LT11.09.2019
LV11.09.2019
PL11.09.2019
RO11.09.2019
RS11.09.2019
SI11.09.2019
SK11.09.2019
SM11.09.2019
BG11.12.2019
GR12.12.2019
IS12.01.2020
Former [2020/36]AL11.09.2019
AT11.09.2019
CZ11.09.2019
DK11.09.2019
EE11.09.2019
FI11.09.2019
HR11.09.2019
LT11.09.2019
LV11.09.2019
PL11.09.2019
RO11.09.2019
RS11.09.2019
SK11.09.2019
SM11.09.2019
BG11.12.2019
GR12.12.2019
IS12.01.2020
Former [2020/27]AL11.09.2019
AT11.09.2019
CZ11.09.2019
EE11.09.2019
FI11.09.2019
HR11.09.2019
LT11.09.2019
LV11.09.2019
PL11.09.2019
RO11.09.2019
RS11.09.2019
SK11.09.2019
SM11.09.2019
BG11.12.2019
GR12.12.2019
IS24.02.2020
Former [2020/25]AL11.09.2019
AT11.09.2019
CZ11.09.2019
EE11.09.2019
FI11.09.2019
HR11.09.2019
LT11.09.2019
LV11.09.2019
PL11.09.2019
RO11.09.2019
RS11.09.2019
SK11.09.2019
BG11.12.2019
GR12.12.2019
IS24.02.2020
Former [2020/23]AL11.09.2019
AT11.09.2019
EE11.09.2019
FI11.09.2019
HR11.09.2019
LT11.09.2019
LV11.09.2019
PL11.09.2019
RO11.09.2019
RS11.09.2019
BG11.12.2019
GR12.12.2019
Former [2020/22]AL11.09.2019
EE11.09.2019
FI11.09.2019
HR11.09.2019
LT11.09.2019
LV11.09.2019
RS11.09.2019
BG11.12.2019
GR12.12.2019
Former [2020/15]AL11.09.2019
FI11.09.2019
HR11.09.2019
LT11.09.2019
LV11.09.2019
RS11.09.2019
BG11.12.2019
GR12.12.2019
Former [2020/11]FI11.09.2019
HR11.09.2019
LT11.09.2019
LV11.09.2019
RS11.09.2019
BG11.12.2019
GR12.12.2019
Former [2020/10]FI11.09.2019
LT11.09.2019
BG11.12.2019
Former [2020/09]FI11.09.2019
LT11.09.2019
Former [2020/08]LT11.09.2019
Cited inInternational search[A]EP0164656  (PFEIFER & LANGEN [DE]) [A] 11,12 * claims 1-19 *;
 [Y]US4767614  (SCARPA IOANNIS S [US], et al) [Y] 10,13 * example 1 *;
 [A]US5229277  (DAY DONAL F [US], et al) [A] 10,13 * the whole document *;
 [Y]WO2010129839  (TATE & LYLE INGREDIENTS FRANCE [FR], et al) [Y] 10,13 * example 4 *;
 [A]WO2010128859  (UNIV GRONINGEN [NL], et al) [A] 11,12 * page 9 - page 12 *;
 [Y]  - DOLS M ET AL, "Characterization of the different dextransucrase activities excreted in glucose, fructose, or sucrose medium by Leuconostoc mesenteroides NRRL B-1299", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, (199804), vol. 64, no. 4, ISSN 0099-2240, pages 1298 - 1302, XP002360116 [Y] 10,13 * page 1299 - page 1301 *

DOI:   http://dx.doi.org/10.1128/AEM.64.4.1298-1302.1998
 [Y]  - SIMPSON C ET AL, "Four glucosyltransferases, GtfJ, GtfK, GtfL, and GtfM from Streptococcus salivarius ATCC 25975", MICROBIOLOGY AND IMMUNOLOGY, CENTER FOR ACADEMIC PUBLICATIONS JAPAN|, JP, (199506), vol. 141, no. 6, ISSN 0385-5600, pages 1451 - 1460, XP002082272 [Y] 10,13 * table 2 *
 [Y]  - Anonymous, "Dextrans", (20140120), URL: https://web.archive.org/web/20140120040848/http://www.sigmaaldrich.com/life-science/biochemicals/biochemical-products.html?TablePage=22696471, (20151005), XP055218107 [Y] 10,13 * page 1 - page 2 *
 [Y]  - Vicki Caligur, "Dextran and Related Polysaccharides", BioFiles, (2008), URL: http://www.sigmaaldrich.com/content/dam/sigma-aldrich/articles/biofiles/volume3.10a17/Dextran-and-Related-Polysaccharides.pdf, (20151005), XP055218106 [Y] 10,13 * page 1 - page 2 *
 [Y]  - ELVIRA KHALIKOVA ET AL, "Microbial Dextran-Hydrolyzing Enzymes: Fundamentals and Applications", MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, (200506), vol. 69, no. 2, doi:10.1128/JMBR.69.2.306-325.2005, pages 306 - 325306, XP055218315 [Y] 10,13 * page 307 *

DOI:   http://dx.doi.org/10.1128/MMBR.69.2.306-325.2005
 [A]  - S. A. F. T. VAN HIJUM ET AL, "Structure-Function Relationships of Glucansucrase and Fructansucrase Enzymes from Lactic Acid Bacteria", MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, (200603), vol. 70, no. 1, doi:10.1128/MMBR.70.1.157-176.2006, ISSN 1092-2172, pages 157 - 176, XP055179067 [A] 1-13 * the whole document *

DOI:   http://dx.doi.org/10.1128/MMBR.70.1.157-176.2006
 [XP]  - "SubName: Full=Alternansucrase {ECO:0000313|EMBL:CDX66895.1}; EC=2.4.1.140 {ECO:0000313|EMBL:CDX66895.1};", UniProt, (20150204), Database accession no. A0A0A1IPZ8, URL: EBI, XP002745403 [XP] 1 * sequence . *
by applicantUS5229277
 EP2365084
    - MAGE; KABAT, "Immunochemical studies on dextrans", III. THE SPECIFICITIES OF RABBIT ANTIDEXTRANS, (1963), vol. 91, pages 634 - 640
    - LEMHUIS ET AL., "Glucansucrases: Three-dimensional structures, reactions, mechanism, alpha-glucan analysis and their implications in biotechnology and food applications", JOURNAL OF BIOTECHNOLOGY, (201301), vol. 163, no. 2, doi:doi:10.1016/j.jbiotec.2012.06.037, pages 250 - 272, XP055102852

DOI:   http://dx.doi.org/10.1016/j.jbiotec.2012.06.037
    - SUMNER; HOWELL, "A method for determination of invertase activity", JOURNAL OF BIOLOGICAL CHEMISTRY, (1935), vol. 108, no. 51
    - "One-step synthesis of isomalto-oligosaccharide syrups and dextrans of controlled size using engineered dextransucrase", MOULIS C; VACA MEDINA G; SUWANNARANGSEE S; MONSAN P; REMAUD-SIMEON M; POTOCKI-VERONESE G, Biocatal. Biotransformation, TAYLOR & FRANCIS, (2008), pages 141 - 151
    - KIM ET AL., "Dextran molecular size and degree of branching as a function of sucrose concentration, pH, and temperature of reaction of Leuconostoc mesenteroides B-512FMCM dextransucrase", CARBOHYDRATE RESEARCH, (2003), vol. 338, doi:doi:10.1016/S0008-6215(03)00148-4, pages 1183 - 1189, XP004424302

DOI:   http://dx.doi.org/10.1016/S0008-6215(03)00148-4
    - MOULIS ET AL., "High-level production and purification of a fully active recombinant dextransucrase from Leuconostoc mesenteroides NRRL B-512F", FEMS MICROBIOLOGY LETTERS, (200608), vol. 261, no. 2, doi:doi:10.1111/j.1574-6968.2006.00347.x, pages 203 - 210, XP002406211

DOI:   http://dx.doi.org/10.1111/j.1574-6968.2006.00347.x
    - KOTHARI ET AL., "Structural Characterization of Enzymatically Synthesized Dextran and Oligosaccharides from Leuconostoc mesenteroides NRRL B-1426 Dextransucrase. ISSN 0006-2979", BIOCHEMISTRY (MOSCOW, (2013), vol. 78, no. 10, pages 1164 - 1170
    - AMARI ET AL., "Characterization of a novel dextransucrase from Weissella confusa isolated from sourdough", APPL MICROBIOL BIOTECHNOL, (2013), vol. 97, pages 5413 - 5422
    - KRALJ ET AL., "Glucan synthesis in the genus Lactobacillus: isolation and characterization of glucansucrase genes, enzymes and glucan products from six different strains", MICROBIOLOGY, (2004), vol. 150, doi:doi:10.1099/mic.0.27321-0, pages 3681 - 3690, XP002360114

DOI:   http://dx.doi.org/10.1099/mic.0.27321-0
    - STRIEGEL ET AL., "An SEC/MALS study of alternan degradation during size-exclusion chromatographic analysis", ANAL BIOANAL CHEM, (2009), vol. 394, doi:doi:10.1007/s00216-009-2895-5, pages 1887 - 1893, XP019736608

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    - GOULAS, A. K. ET AL., "Synthesis of isomaltoligosaccharides and oligodextrans by the combined use of dextransucrase and dextransase", ENZYME MICROB. TECHNOL., (2004), vol. 35, pages 327 - 338
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DOI:   http://dx.doi.org/10.1002/jctb.1322
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.