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Extract from the Register of European Patents

EP About this file: EP3137084

EP3137084 - BENZYL AMILORIDE FOR THE TREATMENT OF PSORIASIS [Right-click to bookmark this link]
Former [2017/10]EPITHELIAL ION CHANNEL (ENAC) BLOCKERS TO TREAT PSORIASIS
[2019/28]
StatusNo opposition filed within time limit
Status updated on  30.10.2020
Database last updated on 03.10.2024
FormerThe patent has been granted
Status updated on  22.11.2019
FormerGrant of patent is intended
Status updated on  09.07.2019
FormerExamination is in progress
Status updated on  23.11.2018
FormerRequest for examination was made
Status updated on  03.02.2017
FormerThe international publication has been made
Status updated on  31.10.2016
Most recent event   Tooltip08.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 10.08.2022  [2022/32]
Applicant(s)For all designated states
The Board of Trustees of the Leland Stanford Junior University
Office of the General Counsel
Building 170, Third Floor, Main Quad
P.O. Box 20386
Stanford, CA 94305-2038 / US
For all designated states
U.S. Government Represented by the Department of Veteran Affairs
810 Vermont Avenue NW
Washington DC 20420 / US
[2019/38]
Former [2017/48]For all designated states
The Board of Trustees of the Leland Stanford Junior University
Office of the General Counsel
Building 170, 3rd Floor, Main Quad
P.O. Box 20386
Stanford, CA 94305-2038 / US
For all designated states
U.S. Government Represented by the Department of Veteran Affairs
810 Vermont Avenue NW
Washington DC 20420 / US
Former [2017/10]For all designated states
The Board of Trustees of the Leland Stanford Junior University
Office of the General Counsel
Building 170, 3rd Floor, Main Quad
P.O. Box 20386
Stanford, CA 94305-2038 / US
Inventor(s)01 / MARINKOVICH, Peter M.
43 Woodhill Drive
Redwood City, California 94061 / US
02 / BUTTE, Atul J.
2020 Monterey Avenue
Menlo Park, California 94025 / US
03 / NASRALLAH, Mazen
109 Thorndike Street
Cambridge, MA 02141 / US
04 / WINGE, Carl Gustaf Maarten
2011 California Street
Apt. 14A
Mountain View, California 94040 / US
 [2017/10]
Representative(s)Mewburn Ellis LLP
Aurora Building
Counterslip
Bristol BS1 6BX / GB
[N/P]
Former [2019/52]Mewburn Ellis LLP
City Tower
40 Basinghall Street
London EC2V 5DE / GB
Former [2017/10]Sutcliffe, Nicholas Robert, et al
Mewburn Ellis LLP
City Tower
40 Basinghall Street
London EC2V 5DE / GB
Application number, filing date15786354.901.05.2015
[2017/10]
WO2015US28820
Priority number, dateUS201461987691P02.05.2014         Original published format: US 201461987691 P
[2017/10]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2015168574
Date:05.11.2015
Language:EN
[2015/44]
Type: A1 Application with search report 
No.:EP3137084
Date:08.03.2017
Language:EN
The application published by WIPO in one of the EPO official languages on 05.11.2015 takes the place of the publication of the European patent application.
[2017/10]
Type: B1 Patent specification 
No.:EP3137084
Date:25.12.2019
Language:EN
[2019/52]
Search report(s)International search report - published on:US05.11.2015
(Supplementary) European search report - dispatched on:EP21.11.2017
ClassificationIPC:A61K31/4965, A61K45/06, A61P17/06
[2017/51]
CPC:
A61K31/4965 (EP); A61K45/06 (EP); A61P17/06 (EP)
C-Set:
A61K31/4965, A61K2300/00 (EP)
Former IPC [2017/10]A61K31/4965
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/10]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
TitleGerman:BENZYL AMILORID ZUR BEHANDLUNG VON PSORIASIS[2019/28]
English:BENZYL AMILORIDE FOR THE TREATMENT OF PSORIASIS[2019/28]
French:AMILORIDE DE BENZYLE POUR LE TRAITEMENT DU PSORIASIS[2019/28]
Former [2017/10]EPITHELIALE IONENKANALBLOCKER ZUR BEHANDLUNG VON PSORIASIS
Former [2017/10]EPITHELIAL ION CHANNEL (ENAC) BLOCKERS TO TREAT PSORIASIS
Former [2017/10]INHIBITEURS DES CANAUX SODIQUES ÉPITHÉLIAUX (ENAC) POUR TRAITER LE PSORIASIS
Entry into regional phase10.11.2016National basic fee paid 
10.11.2016Search fee paid 
10.11.2016Designation fee(s) paid 
10.11.2016Examination fee paid 
Examination procedure31.10.2016Date on which the examining division has become responsible
10.11.2016Examination requested  [2017/10]
27.03.2018Amendment by applicant (claims and/or description)
27.11.2018Despatch of a communication from the examining division (Time limit: M06)
30.05.2019Reply to a communication from the examining division
10.07.2019Communication of intention to grant the patent
18.11.2019Fee for grant paid
18.11.2019Fee for publishing/printing paid
18.11.2019Receipt of the translation of the claim(s)
Opposition(s)28.09.2020No opposition filed within time limit [2020/49]
Fees paidRenewal fee
30.05.2017Renewal fee patent year 03
25.05.2018Renewal fee patent year 04
31.05.2019Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU01.05.2015
AL25.12.2019
AT25.12.2019
CY25.12.2019
CZ25.12.2019
DK25.12.2019
EE25.12.2019
ES25.12.2019
FI25.12.2019
HR25.12.2019
IT25.12.2019
LT25.12.2019
LV25.12.2019
MK25.12.2019
NL25.12.2019
PL25.12.2019
RO25.12.2019
RS25.12.2019
SE25.12.2019
SI25.12.2019
SK25.12.2019
SM25.12.2019
TR25.12.2019
BG25.03.2020
NO25.03.2020
GR26.03.2020
IS25.04.2020
PT20.05.2020
[2022/32]
Former [2022/27]HU01.05.2015
AL25.12.2019
AT25.12.2019
CY25.12.2019
CZ25.12.2019
DK25.12.2019
EE25.12.2019
ES25.12.2019
FI25.12.2019
HR25.12.2019
IT25.12.2019
LT25.12.2019
LV25.12.2019
NL25.12.2019
PL25.12.2019
RO25.12.2019
RS25.12.2019
SE25.12.2019
SI25.12.2019
SK25.12.2019
SM25.12.2019
TR25.12.2019
BG25.03.2020
NO25.03.2020
GR26.03.2020
IS25.04.2020
PT20.05.2020
Former [2021/10]AL25.12.2019
AT25.12.2019
CZ25.12.2019
DK25.12.2019
EE25.12.2019
ES25.12.2019
FI25.12.2019
HR25.12.2019
IT25.12.2019
LT25.12.2019
LV25.12.2019
NL25.12.2019
PL25.12.2019
RO25.12.2019
RS25.12.2019
SE25.12.2019
SI25.12.2019
SK25.12.2019
SM25.12.2019
BG25.03.2020
NO25.03.2020
GR26.03.2020
IS25.04.2020
PT20.05.2020
Former [2020/51]AL25.12.2019
CZ25.12.2019
DK25.12.2019
EE25.12.2019
ES25.12.2019
FI25.12.2019
HR25.12.2019
LT25.12.2019
LV25.12.2019
NL25.12.2019
RO25.12.2019
RS25.12.2019
SE25.12.2019
SI25.12.2019
SK25.12.2019
SM25.12.2019
BG25.03.2020
NO25.03.2020
GR26.03.2020
IS25.04.2020
PT20.05.2020
Former [2020/47]AL25.12.2019
CZ25.12.2019
DK25.12.2019
EE25.12.2019
ES25.12.2019
FI25.12.2019
HR25.12.2019
LT25.12.2019
LV25.12.2019
NL25.12.2019
RO25.12.2019
RS25.12.2019
SE25.12.2019
SK25.12.2019
SM25.12.2019
BG25.03.2020
NO25.03.2020
GR26.03.2020
IS25.04.2020
PT20.05.2020
Former [2020/40]AL25.12.2019
CZ25.12.2019
EE25.12.2019
FI25.12.2019
HR25.12.2019
LT25.12.2019
LV25.12.2019
NL25.12.2019
RO25.12.2019
RS25.12.2019
SE25.12.2019
SK25.12.2019
SM25.12.2019
BG25.03.2020
NO25.03.2020
GR26.03.2020
IS25.04.2020
PT20.05.2020
Former [2020/37]AL25.12.2019
CZ25.12.2019
EE25.12.2019
FI25.12.2019
HR25.12.2019
LT25.12.2019
LV25.12.2019
NL25.12.2019
RO25.12.2019
RS25.12.2019
SE25.12.2019
SK25.12.2019
SM25.12.2019
BG25.03.2020
NO25.03.2020
GR26.03.2020
PT20.05.2020
Former [2020/36]AL25.12.2019
CZ25.12.2019
EE25.12.2019
FI25.12.2019
HR25.12.2019
LT25.12.2019
LV25.12.2019
NL25.12.2019
RO25.12.2019
RS25.12.2019
SE25.12.2019
BG25.03.2020
NO25.03.2020
GR26.03.2020
PT20.05.2020
Former [2020/35]AL25.12.2019
CZ25.12.2019
FI25.12.2019
HR25.12.2019
LT25.12.2019
LV25.12.2019
NL25.12.2019
RO25.12.2019
RS25.12.2019
SE25.12.2019
BG25.03.2020
NO25.03.2020
GR26.03.2020
Former [2020/32]AL25.12.2019
FI25.12.2019
HR25.12.2019
LT25.12.2019
LV25.12.2019
NL25.12.2019
RS25.12.2019
SE25.12.2019
BG25.03.2020
NO25.03.2020
GR26.03.2020
Former [2020/25]FI25.12.2019
HR25.12.2019
LT25.12.2019
LV25.12.2019
RS25.12.2019
SE25.12.2019
BG25.03.2020
NO25.03.2020
GR26.03.2020
Former [2020/23]FI25.12.2019
LT25.12.2019
LV25.12.2019
SE25.12.2019
BG25.03.2020
NO25.03.2020
GR26.03.2020
Former [2020/22]FI25.12.2019
LT25.12.2019
SE25.12.2019
BG25.03.2020
NO25.03.2020
Former [2020/21]NO25.03.2020
Documents cited:Search[X]WO02085367  (UAB RESEARCH FOUNDATION [US]) [X] 9,10 * example - *;
 [X]JP2006232684  (QUALITAS KK, et al) [X] 9,11 * abstract *;
 [X]US2014011817  (XIONG ZHIGANG [US], et al) [X] 9,12 * claims 37,38 *;
 [A]  - RAHMAN M ET AL, "Classical to current approach for treatment of psoriasis: a review", ENDOCRINE, METABOLIC & IMMUNE DISORDERS - DRUG TARGETS, BENTHAM SCIENCE PUBLISHERS LTD, BUSSUM, NL, (20120901), vol. 12, no. 3, doi:10.2174/187153012802002901, ISSN 1871-5303, pages 287 - 302, XP002742331 [A] 1-12 * the whole document *

DOI:   http://dx.doi.org/10.2174/187153012802002901
 [A]  - SIMONA FRATESCHI ET AL, "The Epithelial Sodium Channel ENaC and its Regulators in the Epidermal Permeability Barrier Function", THE OPEN DERMATOLOGY JOURNAL, NL, (20100101), vol. 4, no. 1, doi:10.2174/1874372201004010027, ISSN 1874-3722, pages 27 - 35, XP055422684 [A] 1-8 * page 28, column r - page 32 *

DOI:   http://dx.doi.org/10.2174/1874372201004010027
International search[Y]US6264975  (BOUCHER JR RICHARD C [US]) [Y] 2, 3 * entire document *;
 [A]US2004087480  (RANE STANLEY G [US], et al) [A] 1-12 * entire document *;
 [A]US6903105  (JOHNSON MICHAEL R [US]) [A] 1-12* entire document *;
 [XY]US2006127318  (LIEDTKE RAINER K [DE]) [X] 1, 5-7, 9, 11 * entire document * [Y] 2, 3, 8, 10;
 [A]US2007161543  (YU RUEY J [US], et al) [A] 1-12 * entire document *;
 [Y]US2011280845  (EDINGER JAMES W [US], et al) [Y] 8, 10 * entire document *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.